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The map label for this gene is argE [H]

Identifier: 66043420

GI number: 66043420

Start: 162761

End: 163918

Strand: Reverse

Name: argE [H]

Synonym: Psyr_0150

Alternate gene names: 66043420

Gene position: 163918-162761 (Counterclockwise)

Preceding gene: 66043421

Following gene: 66043419

Centisome position: 2.69

GC content: 63.99

Gene sequence:

>1158_bases
ATGAGCCCCCGCGCACTGGAAATCCTCAAGCGTCTGATCGCCTTCGACACCGTTTCGTCGGAGCCGAACATGGCGCTGAT
CGAATACGTCCGCGAACTGCTGGCCAGCAAAGGCATCGAGTCGCTGATCGTCAAGGACGAGACCGGCAAGAAAGCCAACC
TGTTCGCCAGCACCGGCCCGCGGGAAGTGCCGGGCGTGCTGCTGTCCGGCCACACCGACGTGGTTCCTGCGGCCGGTCAG
GCGTGGACGATGCCACCGTTTCAGGCGACCCTGCGTGACGGGCGCATCTACGGCCGTGGCACCTGCGACATGAAGGGCTT
TATCGCCCTGGCTATCGACGCGATGCTCGATGCTGCGGACATGCCCCTGACGCGCCCGCTGCAACTGGCGCTGTCCCATG
ACGAAGAGATCGGCTGCGTCGGCGTGCGGCGGCTGCTCGACGTCCTGCATCTGGCACCGGTACGTCCGTTCCTGTGCGTG
GTTGGCGAGCCGACCCTGATGCAGTTCGCCGTCGGTCACAAGGGCAAGGCGTCCTATCGCACCTTCTGTCGAGGTCAGGA
GGCGCATTCCTCGCTGGCCCCAAGAGCGGTCAACGCGATTCACCTGGCCAGCGACTTCATCGCCGAACTGCGCAAGAGCC
AGAAGCAGATCGAACAGCAAGGCGCGCGTGACGAGGGTTACGACATCCCTTACAGCACCGTACACATCGGCCGTATCGAT
GGCGGCAAGGCGCTGAACATCGTGCCCAACCTGTGCACCCTGGAATTCGAATACCGCAACCTGCCGGGCGACAACCCCGA
TGCGTTGCTGGAGCAGTTGCGCGAGCGTGCCGAGGTGCTGGTACGTGAAGCGCGACAGCTGTCGGGTGTGGCAGACATCG
AGATCGAGGTCATGAACGAATACCCGGCGCTGGAGACCCATCCAAGCGTTGAGGCGGTGCGCCTGCTGCACGCGTTTGCC
GAGCCGGGCACACAGCACATCAAGGTCTCGTATGGCACCGAGGGCGGCCTGTTCGCCGGGCGCCTCAACGTGCCGGTCGT
GGTTTGCGGTCCGGGTTCCATCGAGCAGGCACACAAGCCGGACGAGTTTATCGACGAGAGCCAGATGGACGCAGGCGAGC
GCTTTTTGCAGAGCCTGCTGGGCTCGCTGAAGCAGTAG

Upstream 100 bases:

>100_bases
TCAGCACCGGCACCACCAGCACCTCGATCAGCCCGTTCGACATTCGCCGGTTTGATGTCAGCCTTGTGGACAACCTCACT
GAACAGACGAGTAAAGCCTC

Downstream 100 bases:

>100_bases
AGGCTGCCGTCCGCAGGCAAATTTCAGCATCGGACGCTGCCGTTATCGCGCTTTCAGCATCCTGGACTGTGGCGTCTGCC
TAGACTGGCAATCATCCCGG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSPRALEILKRLIAFDTVSSEPNMALIEYVRELLASKGIESLIVKDETGKKANLFASTGPREVPGVLLSGHTDVVPAAGQ
AWTMPPFQATLRDGRIYGRGTCDMKGFIALAIDAMLDAADMPLTRPLQLALSHDEEIGCVGVRRLLDVLHLAPVRPFLCV
VGEPTLMQFAVGHKGKASYRTFCRGQEAHSSLAPRAVNAIHLASDFIAELRKSQKQIEQQGARDEGYDIPYSTVHIGRID
GGKALNIVPNLCTLEFEYRNLPGDNPDALLEQLRERAEVLVREARQLSGVADIEIEVMNEYPALETHPSVEAVRLLHAFA
EPGTQHIKVSYGTEGGLFAGRLNVPVVVCGPGSIEQAHKPDEFIDESQMDAGERFLQSLLGSLKQ

Sequences:

>Translated_385_residues
MSPRALEILKRLIAFDTVSSEPNMALIEYVRELLASKGIESLIVKDETGKKANLFASTGPREVPGVLLSGHTDVVPAAGQ
AWTMPPFQATLRDGRIYGRGTCDMKGFIALAIDAMLDAADMPLTRPLQLALSHDEEIGCVGVRRLLDVLHLAPVRPFLCV
VGEPTLMQFAVGHKGKASYRTFCRGQEAHSSLAPRAVNAIHLASDFIAELRKSQKQIEQQGARDEGYDIPYSTVHIGRID
GGKALNIVPNLCTLEFEYRNLPGDNPDALLEQLRERAEVLVREARQLSGVADIEIEVMNEYPALETHPSVEAVRLLHAFA
EPGTQHIKVSYGTEGGLFAGRLNVPVVVCGPGSIEQAHKPDEFIDESQMDAGERFLQSLLGSLKQ
>Mature_384_residues
SPRALEILKRLIAFDTVSSEPNMALIEYVRELLASKGIESLIVKDETGKKANLFASTGPREVPGVLLSGHTDVVPAAGQA
WTMPPFQATLRDGRIYGRGTCDMKGFIALAIDAMLDAADMPLTRPLQLALSHDEEIGCVGVRRLLDVLHLAPVRPFLCVV
GEPTLMQFAVGHKGKASYRTFCRGQEAHSSLAPRAVNAIHLASDFIAELRKSQKQIEQQGARDEGYDIPYSTVHIGRIDG
GKALNIVPNLCTLEFEYRNLPGDNPDALLEQLRERAEVLVREARQLSGVADIEIEVMNEYPALETHPSVEAVRLLHAFAE
PGTQHIKVSYGTEGGLFAGRLNVPVVVCGPGSIEQAHKPDEFIDESQMDAGERFLQSLLGSLKQ

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=370, Percent_Identity=32.972972972973, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1788816, Length=349, Percent_Identity=26.647564469914, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551016, Length=390, Percent_Identity=26.1538461538462, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42049; Mature: 41918

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRALEILKRLIAFDTVSSEPNMALIEYVRELLASKGIESLIVKDETGKKANLFASTGP
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCC
REVPGVLLSGHTDVVPAAGQAWTMPPFQATLRDGRIYGRGTCDMKGFIALAIDAMLDAAD
CCCCCEEEECCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCC
MPLTRPLQLALSHDEEIGCVGVRRLLDVLHLAPVRPFLCVVGEPTLMQFAVGHKGKASYR
CCCCCCHHHEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCHHHH
TFCRGQEAHSSLAPRAVNAIHLASDFIAELRKSQKQIEQQGARDEGYDIPYSTVHIGRID
HHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECC
GGKALNIVPNLCTLEFEYRNLPGDNPDALLEQLRERAEVLVREARQLSGVADIEIEVMNE
CCCEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
YPALETHPSVEAVRLLHAFAEPGTQHIKVSYGTEGGLFAGRLNVPVVVCGPGSIEQAHKP
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCEEEECCCCCCCCCCC
DEFIDESQMDAGERFLQSLLGSLKQ
HHHHCHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPRALEILKRLIAFDTVSSEPNMALIEYVRELLASKGIESLIVKDETGKKANLFASTGP
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCC
REVPGVLLSGHTDVVPAAGQAWTMPPFQATLRDGRIYGRGTCDMKGFIALAIDAMLDAAD
CCCCCEEEECCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCC
MPLTRPLQLALSHDEEIGCVGVRRLLDVLHLAPVRPFLCVVGEPTLMQFAVGHKGKASYR
CCCCCCHHHEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCHHHH
TFCRGQEAHSSLAPRAVNAIHLASDFIAELRKSQKQIEQQGARDEGYDIPYSTVHIGRID
HHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECC
GGKALNIVPNLCTLEFEYRNLPGDNPDALLEQLRERAEVLVREARQLSGVADIEIEVMNE
CCCEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
YPALETHPSVEAVRLLHAFAEPGTQHIKVSYGTEGGLFAGRLNVPVVVCGPGSIEQAHKP
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCEEEECCCCCCCCCCC
DEFIDESQMDAGERFLQSLLGSLKQ
HHHHCHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]