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The map label for this gene is xpt [H]

Identifier: 66043347

GI number: 66043347

Start: 81563

End: 82132

Strand: Direct

Name: xpt [H]

Synonym: Psyr_0076

Alternate gene names: 66043347

Gene position: 81563-82132 (Clockwise)

Preceding gene: 66043346

Following gene: 66043349

Centisome position: 1.34

GC content: 59.82

Gene sequence:

>570_bases
GTGGAAGCACTGCACAAGAAAATTCGCGAAGAAGGCATCGTATTGTCCGATCAGGTGCTGAAGGTCGATGCGTTTCTCAA
CCATCAGATCGATCCGGCGCTGATGAAGGAAATCGGCGATGAATTTGCCCGACTGTTTGCCGACGCTGGCGTGACCAAGA
TCGTGACCATTGAGGCTTCCGGCATCGCGCCGGCAGTCATGGCGGGTTTGAACATGGGCGTGCCGGTGATCTTCGCCCGC
AAGCACCAGTCCCTGACCCTGACCGAAAACCTGCTGACGGCGAGTGTGTACTCATTCACCAAGCAGGTGGAAAGCACCGT
GGCAATCTCGCCGCGCCACCTGAGCAGCGACGACAACGTGCTGATCATCGATGACTTCCTGGCCAACGGCAAAGCCTCAC
AGGCGCTGATCTCGATCATCAAACAGGCCGGCGCCACGGTGGCCGGACTGGGCATCGTGATCGAGAAATCCTTCCAGGGC
GGCCGCGCCGAACTGGACGCCCAGGGCTATCGCGTCGAATCCCTGGCGCGGGTCGAATCCCTGGCCGGCGGGGTTGTGAC
GTTCAAGTAA

Upstream 100 bases:

>100_bases
TCGCGGCAACACTGCGCTTGCCGACATTCGCGCCATGCTGAAACGCTAGCCGACACCCTATTGATCATTTATTGCGCAAT
GGCGCAGCCAAGGAATTTAA

Downstream 100 bases:

>100_bases
GGCTCCCGAGGGCGGACGCAGAGCGTCCAGAAAGGCATGCGACGCGGAGCGCCGCACGATAGTTGTGATGATCGTCCCGC
GCGCTCCAGCGTGGGAATGC

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MEALHKKIREEGIVLSDQVLKVDAFLNHQIDPALMKEIGDEFARLFADAGVTKIVTIEASGIAPAVMAGLNMGVPVIFAR
KHQSLTLTENLLTASVYSFTKQVESTVAISPRHLSSDDNVLIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQG
GRAELDAQGYRVESLARVESLAGGVVTFK

Sequences:

>Translated_189_residues
MEALHKKIREEGIVLSDQVLKVDAFLNHQIDPALMKEIGDEFARLFADAGVTKIVTIEASGIAPAVMAGLNMGVPVIFAR
KHQSLTLTENLLTASVYSFTKQVESTVAISPRHLSSDDNVLIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQG
GRAELDAQGYRVESLARVESLAGGVVTFK
>Mature_189_residues
MEALHKKIREEGIVLSDQVLKVDAFLNHQIDPALMKEIGDEFARLFADAGVTKIVTIEASGIAPAVMAGLNMGVPVIFAR
KHQSLTLTENLLTASVYSFTKQVESTVAISPRHLSSDDNVLIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQG
GRAELDAQGYRVESLARVESLAGGVVTFK

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20148; Mature: 20148

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALHKKIREEGIVLSDQVLKVDAFLNHQIDPALMKEIGDEFARLFADAGVTKIVTIEAS
CHHHHHHHHHCCCEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMAGLNMGVPVIFARKHQSLTLTENLLTASVYSFTKQVESTVAISPRHLSSDDNV
CCCHHHHHHCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCE
LIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQGGRAELDAQGYRVESLARVES
EEEECCCCCCCHHHHHHHHHHHHCCCEEEHEEEEEECCCCCCEEECCCCCHHHHHHHHHH
LAGGVVTFK
HCCCEEEEC
>Mature Secondary Structure
MEALHKKIREEGIVLSDQVLKVDAFLNHQIDPALMKEIGDEFARLFADAGVTKIVTIEAS
CHHHHHHHHHCCCEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMAGLNMGVPVIFARKHQSLTLTENLLTASVYSFTKQVESTVAISPRHLSSDDNV
CCCHHHHHHCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCE
LIIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQGGRAELDAQGYRVESLARVES
EEEECCCCCCCHHHHHHHHHHHHCCCEEEHEEEEEECCCCCCEEECCCCCHHHHHHHHHH
LAGGVVTFK
HCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA