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The map label for this gene is fmt [H]

Identifier: 66043289

GI number: 66043289

Start: 22042

End: 22986

Strand: Reverse

Name: fmt [H]

Synonym: Psyr_0018

Alternate gene names: 66043289

Gene position: 22986-22042 (Counterclockwise)

Preceding gene: 66043290

Following gene: 66043288

Centisome position: 0.38

GC content: 65.82

Gene sequence:

>945_bases
ATGACTGAGCCACTGCGCATCGTCTTCGCCGGCACCCCGGAATTCGCCGCCGAACACCTCAAGGCCCTGCTCGACAGCCC
TCACCAGATCGTCGCCGTGTACACCCAGCCCGATCGCCCGGCCGGTCGTGGACAAAAGCTGATGCCCAGCCCGGTCAAGC
AACTGGCGCTGCAACATGACGTACCGGTCATGCAGCCGCCCACACTGCGCGATCCTGCTGCGCAGGCTGAACTGGCAGCG
CTGCAACCCGATTTGATGGTGGTCGTCGCCTACGGCCTGATCCTGCCGCAAGTGGTGCTGGATATTCCGCGCCTGGGCTG
CATCAACAGCCATGCGTCGCTGCTGCCGCGCTGGCGCGGTGCGGCGCCGATTCAGCGCGCGGTGCAGGCCGGTGATGCCG
AGAGCGGCGTAACCGTGATGCGCATGGAAGCGGGCCTGGACACCGGGCCGATGCTGCTCAAGGCGGTCACCCCGATTACC
GCGCAGGACACGGGCGGCACGCTGCATGATCGCCTGGCCGAACTCGGTCCGCCTGCTGTGTTGCAGGCTATTGCCGGTCT
GGCGGACGGTACGCTGGTCGGCGAGGTTCAGGATGACAGCCTGGCCAACTACGCCCATAAGCTGAACAAGGACGAAGCAC
GCCTGGACTGGACGCGTCCGGCCGATGAGCTTGAACGCCTGGTCCGCGCCTTCAACCCCTGGCCGATCTGTCACAGCACG
CTGAACGAAGAAACCCTGAAAGTCCTGGCCGCCGATCTGGCCGAAGGGCAGGGCGCGCCGGGGACGATTCTTGGCGCCAG
CAAGGATGGCCTGATCGTCGCCTGCGGGCAGAACGCGCTGCGCCTGACCCGTCTGCAATTGCCGGGCGGCAAGCCGCTGA
ACTTCACTGACCTGTTCAACAGCCGCCGCGAGAAATTTGCCATCGGCACGGTGCTGGGCCAATGA

Upstream 100 bases:

>100_bases
ACCGGATCAAGAAGAAGCTCGAAAAGCAGCACAAGCTCAACGCCTGATCCGTCGTTACCCCAAAAGGCCTGAACAGGCCT
TTTTTTATAATGAGAACTCC

Downstream 100 bases:

>100_bases
ACCCGCGTCTGGCCGCCGCCAAGGCACTGGCTGCCGTACTCAGCGGCAAGGCCTCGCTGAACAGCTCGTTGCCGACTCAA
CTGGACAAGGTCGAGGTGCG

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTEPLRIVFAGTPEFAAEHLKALLDSPHQIVAVYTQPDRPAGRGQKLMPSPVKQLALQHDVPVMQPPTLRDPAAQAELAA
LQPDLMVVVAYGLILPQVVLDIPRLGCINSHASLLPRWRGAAPIQRAVQAGDAESGVTVMRMEAGLDTGPMLLKAVTPIT
AQDTGGTLHDRLAELGPPAVLQAIAGLADGTLVGEVQDDSLANYAHKLNKDEARLDWTRPADELERLVRAFNPWPICHST
LNEETLKVLAADLAEGQGAPGTILGASKDGLIVACGQNALRLTRLQLPGGKPLNFTDLFNSRREKFAIGTVLGQ

Sequences:

>Translated_314_residues
MTEPLRIVFAGTPEFAAEHLKALLDSPHQIVAVYTQPDRPAGRGQKLMPSPVKQLALQHDVPVMQPPTLRDPAAQAELAA
LQPDLMVVVAYGLILPQVVLDIPRLGCINSHASLLPRWRGAAPIQRAVQAGDAESGVTVMRMEAGLDTGPMLLKAVTPIT
AQDTGGTLHDRLAELGPPAVLQAIAGLADGTLVGEVQDDSLANYAHKLNKDEARLDWTRPADELERLVRAFNPWPICHST
LNEETLKVLAADLAEGQGAPGTILGASKDGLIVACGQNALRLTRLQLPGGKPLNFTDLFNSRREKFAIGTVLGQ
>Mature_313_residues
TEPLRIVFAGTPEFAAEHLKALLDSPHQIVAVYTQPDRPAGRGQKLMPSPVKQLALQHDVPVMQPPTLRDPAAQAELAAL
QPDLMVVVAYGLILPQVVLDIPRLGCINSHASLLPRWRGAAPIQRAVQAGDAESGVTVMRMEAGLDTGPMLLKAVTPITA
QDTGGTLHDRLAELGPPAVLQAIAGLADGTLVGEVQDDSLANYAHKLNKDEARLDWTRPADELERLVRAFNPWPICHSTL
NEETLKVLAADLAEGQGAPGTILGASKDGLIVACGQNALRLTRLQLPGGKPLNFTDLFNSRREKFAIGTVLGQ

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=313, Percent_Identity=27.1565495207668, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI164663775, Length=321, Percent_Identity=28.6604361370716, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI21614513, Length=315, Percent_Identity=27.3015873015873, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1789683, Length=314, Percent_Identity=58.5987261146497, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1788589, Length=274, Percent_Identity=28.1021897810219, Blast_Score=124, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI133930964, Length=303, Percent_Identity=26.4026402640264, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550868, Length=305, Percent_Identity=29.8360655737705, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571984, Length=256, Percent_Identity=30.46875, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24585660, Length=266, Percent_Identity=29.3233082706767, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 33546; Mature: 33415

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPLRIVFAGTPEFAAEHLKALLDSPHQIVAVYTQPDRPAGRGQKLMPSPVKQLALQHD
CCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCC
VPVMQPPTLRDPAAQAELAALQPDLMVVVAYGLILPQVVLDIPRLGCINSHASLLPRWRG
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
AAPIQRAVQAGDAESGVTVMRMEAGLDTGPMLLKAVTPITAQDTGGTLHDRLAELGPPAV
CHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHH
LQAIAGLADGTLVGEVQDDSLANYAHKLNKDEARLDWTRPADELERLVRAFNPWPICHST
HHHHHHCCCCCEEEECCCHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHCCCCCHHHHH
LNEETLKVLAADLAEGQGAPGTILGASKDGLIVACGQNALRLTRLQLPGGKPLNFTDLFN
CCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHH
SRREKFAIGTVLGQ
HHHHHEEHHHHCCC
>Mature Secondary Structure 
TEPLRIVFAGTPEFAAEHLKALLDSPHQIVAVYTQPDRPAGRGQKLMPSPVKQLALQHD
CCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCC
VPVMQPPTLRDPAAQAELAALQPDLMVVVAYGLILPQVVLDIPRLGCINSHASLLPRWRG
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
AAPIQRAVQAGDAESGVTVMRMEAGLDTGPMLLKAVTPITAQDTGGTLHDRLAELGPPAV
CHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHH
LQAIAGLADGTLVGEVQDDSLANYAHKLNKDEARLDWTRPADELERLVRAFNPWPICHST
HHHHHHCCCCCEEEECCCHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHCCCCCHHHHH
LNEETLKVLAADLAEGQGAPGTILGASKDGLIVACGQNALRLTRLQLPGGKPLNFTDLFN
CCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHH
SRREKFAIGTVLGQ
HHHHHEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA