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The map label for this gene is ctaD

Identifier: 62391363

GI number: 62391363

Start: 2642734

End: 2644488

Strand: Reverse

Name: ctaD

Synonym: cg2780

Alternate gene names: 62391363

Gene position: 2644488-2642734 (Counterclockwise)

Preceding gene: 62391364

Following gene: 62391362

Centisome position: 80.56

GC content: 55.44

Gene sequence:

>1755_bases
ATGACCGCTGTGGCGCCTAGGGTCGACGGGCACGTCGCCCCTCAGAGGCCCGAGCCGACAGGCCATGCACGCAAGGGCAG
CAAAGCATGGTTAATGATGACCACCACCGACCACAAGCAGCTGGGCATTATGTACATCATTATGTCCTTCAGCTTCTTCT
TCCTCGGTGGCTTGATGGCCCTGCTTATCCGAGCGGAGCTTTTCACCCCTGGTCTGCAGTTCCTGTCTAATGAGCAGTTC
AACCAGCTGTTCACCATGCACGGAACTGTCATGCTGCTGCTGTACGGAACTCCAATTGTTTGGGGTTTTGCTAACTACGT
CCTGCCACTTCAGATCGGTGCGCCTGACGTAGCTTTCCCACGTTTGAATGCTTTCGGCTTCTGGATCACCACCGTCGGTG
GTGTCGCGATGCTGACCGGCTTCCTGACCCCGGGTGGTGCTGCCGACTTCGGTTGGACCATGTACTCCCCACTGTCTGAC
GCAATTCACTCCCCAGGCCTTGGCTCTGACATGTGGATTGTCGGTGTCGGTGCAACTGGTATTGGCTCCGTTGCTTCCGC
AATTAACATGCTCACCACCATCCTCTGCCTCCGCGCACCTGGTATGACCATGTTCCGTATGCCTATTTTCACCTGGAATA
TCTTCGTTGTTTCCGTTCTTGCTCTGCTGATCTTCCCACTGCTGCTCGCTGCTGCACTGGGTGTTCTGTATGACCGCAAG
CTTGGTGGACACCTGTACGATCCAGCTAACGGCGGCTCCCTCCTGTGGCAGCACCTGTTCTGGTTCTTCGGACACCCTGA
GGTTTACGTTCTGGCGCTGCCGTTCTTCGGCATTGTTTCTGAGATCATTCCTGTGTTCTCCCGTAAGCCAATGTTCGGTT
ACGTCGGCCTGATCTTCGCAACCTTGTCCATTGGTGCACTGTCCATGGCTGTGTGGGCTCACCACATGTTCGTTACTGGC
GCAGTTTTGCTTCCGTTCTTCTCCTTCATGACGTTCCTGATTTCGGTTCCTACCGGCGTTAAGTTCTTCAACTGGGTTGG
AACCATGTGGAAGGGTCACATCACTTGGGAAACCCCAATGATCTGGTCTGTTGGCTTCATGGCTACCTTCCTCTTCGGTG
GTCTGACCGGCATTATGCTGGCGTCCCCACCACTGGACTTCCACTTGGCTGACTCCTACTTCCTGATCGCGCACTTCCAC
TACACCCTCTTCGGTACCGTGGTGTTCGCATCGTGTGCAGGCGTTTACTTCTGGTTCCCGAAGATGACTGGCCGCATGAT
GGACGAGCGTCTTGGCAAGATCCACTTCTGGTTGACCTTCGTCGGTTTCCACGGAACCTTCCTCATCCAGCACTGGGTGG
GCAACATGGGTATGCCACGTCGTTACGCTGACTACCTGGATTCTGATGGTTTCACCATCTACAACCAGATCTCCACCGTG
TTCTCCTTCCTGCTTGGCCTGTCTGTCATTCCATTCATCTGGAACGTCTTCAAGTCCTGGCGCTACGGTGAGCTCGTTAC
CGTTGATGATCCTTGGGGTTACGGCAACTCCCTGGAGTGGGCAACCTCCTGCCCTCCTCCTCGCCACAACTTCGCATCCT
TGCCTCGTATCCGCTCCGAGCGCCCTGCGTTCGAGCTGCACTACCCGCACATGATTGAACGCATGCGCGCAGAGGCACAC
ACTGGACATCACGATGATATTAATGCTCCAGAATTGGGTACCGCCCCAGCCCTTGCATCTGACTCCAGCCGCTAA

Upstream 100 bases:

>100_bases
TTGGGTTGGCATCGGATCCTGCCTGTGGCCTAAGATCAGGCAGTGTTGTTAAAGGACGATCGGTAATCCGAATGGATCGT
CCCGTAGTCAGGAGGAACCT

Downstream 100 bases:

>100_bases
AAGCGTCTGATTTAAGTCGGTACCTGACTAAATAAGCACCAGCCCCAGCAGAGATAATCTGCCGGGGCTGGTGCTTTTCA
TATTCCGACTTGGGGCACCC

Product: cytochrome C oxidase polypeptide subunit

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MTAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMALLIRAELFTPGLQFLSNEQF
NQLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFPRLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSD
AIHSPGLGSDMWIVGVGATGIGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRK
LGGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFATLSIGALSMAVWAHHMFVTG
AVLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPMIWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFH
YTLFGTVVFASCAGVYFWFPKMTGRMMDERLGKIHFWLTFVGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTV
FSFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSERPAFELHYPHMIERMRAEAH
TGHHDDINAPELGTAPALASDSSR

Sequences:

>Translated_584_residues
MTAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMALLIRAELFTPGLQFLSNEQF
NQLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFPRLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSD
AIHSPGLGSDMWIVGVGATGIGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRK
LGGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFATLSIGALSMAVWAHHMFVTG
AVLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPMIWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFH
YTLFGTVVFASCAGVYFWFPKMTGRMMDERLGKIHFWLTFVGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTV
FSFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSERPAFELHYPHMIERMRAEAH
TGHHDDINAPELGTAPALASDSSR
>Mature_583_residues
TAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMALLIRAELFTPGLQFLSNEQFN
QLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFPRLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSDA
IHSPGLGSDMWIVGVGATGIGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRKL
GGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFATLSIGALSMAVWAHHMFVTGA
VLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPMIWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFHY
TLFGTVVFASCAGVYFWFPKMTGRMMDERLGKIHFWLTFVGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTVF
SFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSERPAFELHYPHMIERMRAEAHT
GHHDDINAPELGTAPALASDSSR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=41.3255360623782, Blast_Score=363, Evalue=1e-100,
Organism=Escherichia coli, GI1786634, Length=552, Percent_Identity=42.5724637681159, Blast_Score=403, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6226519, Length=538, Percent_Identity=36.9888475836431, Blast_Score=345, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=40.251572327044, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=38.1147540983607, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COX1_CORGL (Q79VD7)

Other databases:

- EMBL:   AJ306417
- EMBL:   AB052748
- EMBL:   BA000036
- EMBL:   BX927155
- RefSeq:   NP_601724.2
- RefSeq:   YP_226765.1
- ProteinModelPortal:   Q79VD7
- SMR:   Q79VD7
- GeneID:   1020472
- GeneID:   3344025
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2780
- KEGG:   cgl:NCgl2437
- HOGENOM:   HBG603668
- OMA:   AFGFWIT
- PhylomeDB:   Q79VD7
- ProtClustDB:   CLSK2519649
- BioCyc:   CGLU196627:CG2780-MONOMER
- BRENDA:   1.9.3.1
- InterPro:   IPR000883
- InterPro:   IPR014241
- Gene3D:   G3DSA:1.20.210.10
- PANTHER:   PTHR10422
- PRINTS:   PR01165
- TIGRFAMs:   TIGR02891

Pfam domain/function: PF00115 COX1; SSF81442 COX1

EC number: =1.9.3.1

Molecular weight: Translated: 65103; Mature: 64972

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50855 COX1; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x153a5230)-; HASH(0x15a9ac6c)-; HASH(0x15ac1344)-; HASH(0x15614328)-; HASH(0x15a9354c)-; HASH(0x15adb87c)-; HASH(0x15a39904)-; HASH(0x15653678)-; HASH(0x15ac1104)-; HASH(0x154dd5ac)-; HASH(0x15ac9e6c)-; HASH(0x15ac9d10)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LLIRAELFTPGLQFLSNEQFNQLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFP
HHHHHHHHCCHHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHCCEEEEEECCCCCCCC
RLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSDAIHSPGLGSDMWIVGVGATG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCC
IGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRK
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFA
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TLSIGALSMAVWAHHMFVTGAVLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCH
IWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFHYTLFGTVVFASCAGVYFWFP
HHHHHHHHHHHHHHHHHHHEECCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHEEHH
KMTGRMMDERLGKIHFWLTFVGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTV
HHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHH
FSFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSE
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
RPAFELHYPHMIERMRAEAHTGHHDDINAPELGTAPALASDSSR
CCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
TAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LLIRAELFTPGLQFLSNEQFNQLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFP
HHHHHHHHCCHHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHCCEEEEEECCCCCCCC
RLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSDAIHSPGLGSDMWIVGVGATG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCC
IGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRK
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFA
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TLSIGALSMAVWAHHMFVTGAVLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCH
IWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFHYTLFGTVVFASCAGVYFWFP
HHHHHHHHHHHHHHHHHHHEECCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHEEHH
KMTGRMMDERLGKIHFWLTFVGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTV
HHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHH
FSFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSE
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
RPAFELHYPHMIERMRAEAHTGHHDDINAPELGTAPALASDSSR
CCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11382224; 11577165; 12948626