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The map label for this gene is serB [H]

Identifier: 62391362

GI number: 62391362

Start: 2641228

End: 2642568

Strand: Reverse

Name: serB [H]

Synonym: cg2779

Alternate gene names: 62391362

Gene position: 2642568-2641228 (Counterclockwise)

Preceding gene: 62391363

Following gene: 62391361

Centisome position: 80.5

GC content: 55.63

Gene sequence:

>1341_bases
ATGTCGTGTTCCGCGCTCAGACATGAGACAATTGTTGCCGTGACTGAACTCATCCAGAATGAATCCCAAGAAATCGCTGA
GCTGGAAGCCGGCCAGCAGGTTGCATTGCGTGAAGGTTATCTTCCTGCGGTGATCACAGTGAGCGGTAAAGACCGCCCAG
GTGTGACTGCCGCGTTCTTTAGGGTCTTGTCCGCTAATCAGGTTCAGGTCTTGGACGTTGAGCAGTCAATGTTCCGTGGC
TTTTTGAACTTGGCGGCGTTTGTGGGTATCGCACCTGAGCGTGTCGAGACCGTCACCACAGGCCTGACTGACACCCTCAA
GGTGCATGGACAGTCCGTGGTGGTGGAGCTGCAGGAAACTGTGCAGTCGTCCCGTCCTCGTTCTTCCCATGTTGTTGTGG
TGTTGGGTGATCCGGTTGATGCGTTGGATATTTCCCGCATTGGTCAGACCCTGGCGGATTACGATGCCAACATTGACACC
ATTCGTGGTATTTCGGATTACCCTGTGACCGGCCTGGAGCTGAAGGTGACTGTGCCGGATGTCAGCCCTGGTGGTGGTGA
AGCGATGCGTAAGGCGCTTGCTGCTCTTACCTCTGAGCTGAATGTGGATATTGCGATTGAGCGTTCTGGTTTGCTGCGTC
GTTCTAAGCGTCTGGTGTGCTTCGATTGTGATTCCACGTTGATCACTGGTGAGGTCATTGAGATGCTGGCGGCTCACGCG
GGCAAGGAAGCTGAAGTTGCGGCAGTTACTGAGCGTGCGATGCGCGGTGAGCTCGATTTCGAGGAGTCTCTGCGTGAGCG
TGTGAAGGCGTTGGCTGGTTTGGATGCGTCGGTGATCGATGAGGTCGCTGCCGCTATTGAGCTGACCCCTGGTGCGCGCA
CCACGATCCGTACGCTGAACCGCATGGGTTACCAGACCGCTGTTGTTTCCGGTGGTTTCATCCAGGTGTTGGAAGGTTTG
GCTGAGGAGTTGGAGTTGGATTATGTCCGCGCCAACACTTTGGAAATCGTTGATGGCAAGCTGACCGGCAACGTCACCGG
AAAGATCGTTGACCGCGCTGCGAAGGCTGAGTTCCTCCGTGAGTTCGCTGCGGATTCTGGCCTGAAGATGTACCAGACTG
TCGCTGTCGGTGATGGCGCTAATGACATCGATATGCTCTCCGCTGCGGGTCTGGGTGTTGCTTTCAACGCGAAGCCTGCG
CTGAAGGAGATTGCGGATACTTCCGTGAACCACCCATTCCTCGACGAGGTTTTGCACATCATGGGCATTTCCCGCGACGA
GATCGATCTGGCGGATCAGGAAGACGGCACTTTCCACCGCGTTCCATTGACCAATGCCTAA

Upstream 100 bases:

>100_bases
GGCTGGTGCTTTTCATATTCCGACTTGGGGCACCCCTGAATACATCTCACCCAATTCCCCATAACTAGACAATTGCCCAG
CAACGACTGATAAGTCTCCA

Downstream 100 bases:

>100_bases
AGATTCGCTTCTCGACGCCCACCTCCTCCTCAAGGCCCGGGCTAGCGACGGGCCACATAGCGAGGATCCTTCGGATCCTT
CGACCGTTCAGGCAATGCAG

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSCSALRHETIVAVTELIQNESQEIAELEAGQQVALREGYLPAVITVSGKDRPGVTAAFFRVLSANQVQVLDVEQSMFRG
FLNLAAFVGIAPERVETVTTGLTDTLKVHGQSVVVELQETVQSSRPRSSHVVVVLGDPVDALDISRIGQTLADYDANIDT
IRGISDYPVTGLELKVTVPDVSPGGGEAMRKALAALTSELNVDIAIERSGLLRRSKRLVCFDCDSTLITGEVIEMLAAHA
GKEAEVAAVTERAMRGELDFEESLRERVKALAGLDASVIDEVAAAIELTPGARTTIRTLNRMGYQTAVVSGGFIQVLEGL
AEELELDYVRANTLEIVDGKLTGNVTGKIVDRAAKAEFLREFAADSGLKMYQTVAVGDGANDIDMLSAAGLGVAFNAKPA
LKEIADTSVNHPFLDEVLHIMGISRDEIDLADQEDGTFHRVPLTNA

Sequences:

>Translated_446_residues
MSCSALRHETIVAVTELIQNESQEIAELEAGQQVALREGYLPAVITVSGKDRPGVTAAFFRVLSANQVQVLDVEQSMFRG
FLNLAAFVGIAPERVETVTTGLTDTLKVHGQSVVVELQETVQSSRPRSSHVVVVLGDPVDALDISRIGQTLADYDANIDT
IRGISDYPVTGLELKVTVPDVSPGGGEAMRKALAALTSELNVDIAIERSGLLRRSKRLVCFDCDSTLITGEVIEMLAAHA
GKEAEVAAVTERAMRGELDFEESLRERVKALAGLDASVIDEVAAAIELTPGARTTIRTLNRMGYQTAVVSGGFIQVLEGL
AEELELDYVRANTLEIVDGKLTGNVTGKIVDRAAKAEFLREFAADSGLKMYQTVAVGDGANDIDMLSAAGLGVAFNAKPA
LKEIADTSVNHPFLDEVLHIMGISRDEIDLADQEDGTFHRVPLTNA
>Mature_445_residues
SCSALRHETIVAVTELIQNESQEIAELEAGQQVALREGYLPAVITVSGKDRPGVTAAFFRVLSANQVQVLDVEQSMFRGF
LNLAAFVGIAPERVETVTTGLTDTLKVHGQSVVVELQETVQSSRPRSSHVVVVLGDPVDALDISRIGQTLADYDANIDTI
RGISDYPVTGLELKVTVPDVSPGGGEAMRKALAALTSELNVDIAIERSGLLRRSKRLVCFDCDSTLITGEVIEMLAAHAG
KEAEVAAVTERAMRGELDFEESLRERVKALAGLDASVIDEVAAAIELTPGARTTIRTLNRMGYQTAVVSGGFIQVLEGLA
EELELDYVRANTLEIVDGKLTGNVTGKIVDRAAKAEFLREFAADSGLKMYQTVAVGDGANDIDMLSAAGLGVAFNAKPAL
KEIADTSVNHPFLDEVLHIMGISRDEIDLADQEDGTFHRVPLTNA

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790849, Length=214, Percent_Identity=45.7943925233645, Blast_Score=175, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6321647, Length=241, Percent_Identity=41.9087136929461, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24661601, Length=219, Percent_Identity=28.310502283105, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 47756; Mature: 47625

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCSALRHETIVAVTELIQNESQEIAELEAGQQVALREGYLPAVITVSGKDRPGVTAAFF
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCCEEEEECCCCCCCHHHHHH
RVLSANQVQVLDVEQSMFRGFLNLAAFVGIAPERVETVTTGLTDTLKVHGQSVVVELQET
HHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHH
VQSSRPRSSHVVVVLGDPVDALDISRIGQTLADYDANIDTIRGISDYPVTGLELKVTVPD
HHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCEEEEEECCC
VSPGGGEAMRKALAALTSELNVDIAIERSGLLRRSKRLVCFDCDSTLITGEVIEMLAAHA
CCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCEEEEECCCCEEHHHHHHHHHHHC
GKEAEVAAVTERAMRGELDFEESLRERVKALAGLDASVIDEVAAAIELTPGARTTIRTLN
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCHHHHHHHH
RMGYQTAVVSGGFIQVLEGLAEELELDYVRANTLEIVDGKLTGNVTGKIVDRAAKAEFLR
HCCCHHEEECCCHHHHHHHHHHHHHHHHEECCEEEEECCEEECCCHHHHHHHHHHHHHHH
EFAADSGLKMYQTVAVGDGANDIDMLSAAGLGVAFNAKPALKEIADTSVNHPFLDEVLHI
HHHCCCCCEEEEEEEECCCCCCHHHHHHCCCCEEECCCHHHHHHHHCCCCCHHHHHHHHH
MGISRDEIDLADQEDGTFHRVPLTNA
HCCCCCCCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure 
SCSALRHETIVAVTELIQNESQEIAELEAGQQVALREGYLPAVITVSGKDRPGVTAAFF
CCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCCEEEEECCCCCCCHHHHHH
RVLSANQVQVLDVEQSMFRGFLNLAAFVGIAPERVETVTTGLTDTLKVHGQSVVVELQET
HHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHH
VQSSRPRSSHVVVVLGDPVDALDISRIGQTLADYDANIDTIRGISDYPVTGLELKVTVPD
HHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCEEEEEECCC
VSPGGGEAMRKALAALTSELNVDIAIERSGLLRRSKRLVCFDCDSTLITGEVIEMLAAHA
CCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCEEEEECCCCEEHHHHHHHHHHHC
GKEAEVAAVTERAMRGELDFEESLRERVKALAGLDASVIDEVAAAIELTPGARTTIRTLN
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCHHHHHHHH
RMGYQTAVVSGGFIQVLEGLAEELELDYVRANTLEIVDGKLTGNVTGKIVDRAAKAEFLR
HCCCHHEEECCCHHHHHHHHHHHHHHHHEECCEEEEECCEEECCCHHHHHHHHHHHHHHH
EFAADSGLKMYQTVAVGDGANDIDMLSAAGLGVAFNAKPALKEIADTSVNHPFLDEVLHI
HHHCCCCCEEEEEEEECCCCCCHHHHHHCCCCEEECCCHHHHHHHHCCCCCHHHHHHHHH
MGISRDEIDLADQEDGTFHRVPLTNA
HCCCCCCCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA