| Definition | Corynebacterium glutamicum ATCC 13032, complete genome. |
|---|---|
| Accession | NC_006958 |
| Length | 3,282,708 |
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The map label for this gene is ftsI [H]
Identifier: 62391003
GI number: 62391003
Start: 2262881
End: 2264836
Strand: Reverse
Name: ftsI [H]
Synonym: cg2375
Alternate gene names: 62391003
Gene position: 2264836-2262881 (Counterclockwise)
Preceding gene: 62391004
Following gene: 62391002
Centisome position: 68.99
GC content: 53.73
Gene sequence:
>1956_bases GTGACCTACCGGCCTAAATCTTCAACCCAGGGCGGCGCACGCAAGCGACGTGTGAACATGGTTACCGCTATCGCATTGGT CATCGCTGGCGTACTGATCATTCGCCTCGGCTGGGTCCAAGTTGTCTGGGGACCAGAACTGTCCCTCAATGCTTCGGAAC AGCGCACCCGCGTGTACGTAGATCCTGCACGTCGTGGAAGCATCGTGGACCGCGAAGGAAACCAGATGGCGTACACGATG CAGGCACGTTCGCTGACGGTTTCTCCGAACATCATGCGTGAGGAATTAAAGACCGGAACTGATTTGGCCTTGCGTTTGGC GGCTGAAGAAACCGATCCGGAAAACGTGGCCAGCTATGTGACCATCGAAGAAGGCAACGCGTATGTTTTTGCGTCTGAAG AACAGCGCGAAACCATTCTGTCCGACAAGGTAGAAGAGCGCATTCAAAGCATTGCGGATCGGATCCCTGAGATCATCAAA TCCCATGACCAAGATGTCACTGGAATTTCCTCTGAGGAGATCCTGGACAAGCTCAATGCTGATAGCCAGTATGAGGTGCT CGTCCGCAATGTTGATCCCGATGTAGCGTCAGAAATCACCGATGAGATGCCCAGCGTCGCAGCTGATCATCAAGACATCC GCCAATACCCAAACGGCGCGATTGGTGAAAACATCATCGGTCGAATCAGCATGGACGGCGAAGGCCAGTTCGGCTTTGAG GCTTCCAACGATTCCCTGTTGGCAGGAAACAACGGTCGCTCAACCCAGGACATGTCCATTTTGGGACAAGCAATCCCGGG CACGTTGAGGGATCAAATTCCAGCCATTGATGGTGCCAGCGTTGAACTCACCGTTGATCTGGATCTGCAAACCTATGTGC AGCAGGCATTGGAGCAGGCGAAAGCTAACTCCGGTGCAGAAAACGCCTCCGCTGTGGTTCTTGATGCCAAGACCGCTGAG GTTTTGGCGATGGCAAACACCGATACCATCAACCCCAACGAAGACACGGGAAAGCAGATTGAGCAGGGCAAGAGCTTTGA CAATCCTTCTGTCACCCACCCCTTCGAGCCTGGTTCTGTAGCCAAGGTGATTACTGCAGCAGGCGTAATTCAAGAGGGCT TGACTACTCCAGATGAAGTGTTGCAGGTACCGGGCAGTATTGAAATGGCCGGTGTTTCTGTCGGTGATGCGTGGGACCAC GGTGTCGTTCCCTACACCACTGCAGGAATTTTTGGTAAGTCCTCGAATGTAGGCACTCTGATGCTTGCGCAGCGTCTTGG TGAAGATAAATTTGCTGATTACCTGGAACGATTCGGTGTGGGACAGCCAACGGGTATTGAGCTTCCGAGCGAATCCCAAG GCCTGCTGCCCGCACGTGAGCAGTGGTCTGGCGGTACTTTTGCTAACCTGCCCATCGGTCAGGGTATGTCGATCACCACG TTGCAAATGGCTGGAATCTACCAAGCCTTGGCCAACGATGGTGAACGCATTCAACCGCGGATCATCAAGAGCGTGACTGA TTCTGACGGAACAGTCCTAGAGCAGCCAGAACCCGATAAAATCCAGGTTGTCAGCGCTGAAGCTGCCCGCACCACGGTGG ATATGTTTAGGTCTGTCACCCAGGTTGATCCAACTGGAGTGCAACAAGGTACCGCTCCAGACGCCTCCATTGAGGGTTAT CAAATCTCAGGTAAGACAGGTACGGCGCAGAAAGTTGACCCCAACACGGGCGCGTACTCTAACTCGCAATACTGGATTAC CTTCGCGGGTATTGCACCCGCTGATGATCCTCGATTTGTTGTAGCCATCATGCTTGATGAGCCAGAACGCGGAGTCCACG GTGGTGGCGGCCAAACCGCAGCACCTTTGTTCAAAGACATCGCCACCTGGTTGCTCAACCGCGACAACATCCCACTGTCT GCAGCCACCGAACCGATCATCCTTCAAGCTCAATAA
Upstream 100 bases:
>100_bases CCGCCGTTCGGCGTATCAGGACGAAAGCAGAAGAGCCGCTAGAGAGCGCGAACTTACGCGACGCAGCGGTAAAGCTAAAG GCGTAAACCAAGAAGAAGGA
Downstream 100 bases:
>100_bases CTCAAACAGAAGTGTCTTTTGTAGAATTTCATAATCTGAACTTTTGTTTGAACTCTTTTCGGCATCACCCACGTGCCGCG TCCGAATTATTAACACCTAG
Product: penicillin-binding protein 2X
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 651; Mature: 650
Protein sequence:
>651_residues MTYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYVDPARRGSIVDREGNQMAYTM QARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYVTIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIK SHDQDVTGISSEEILDKLNADSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFE ASNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQAKANSGAENASAVVLDAKTAE VLAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSVAKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDH GVVPYTTAGIFGKSSNVGTLMLAQRLGEDKFADYLERFGVGQPTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITT LQMAGIYQALANDGERIQPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVTQVDPTGVQQGTAPDASIEGY QISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFVVAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLS AATEPIILQAQ
Sequences:
>Translated_651_residues MTYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYVDPARRGSIVDREGNQMAYTM QARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYVTIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIK SHDQDVTGISSEEILDKLNADSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFE ASNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQAKANSGAENASAVVLDAKTAE VLAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSVAKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDH GVVPYTTAGIFGKSSNVGTLMLAQRLGEDKFADYLERFGVGQPTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITT LQMAGIYQALANDGERIQPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVTQVDPTGVQQGTAPDASIEGY QISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFVVAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLS AATEPIILQAQ >Mature_650_residues TYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYVDPARRGSIVDREGNQMAYTMQ ARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYVTIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIKS HDQDVTGISSEEILDKLNADSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFEA SNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQAKANSGAENASAVVLDAKTAEV LAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSVAKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDHG VVPYTTAGIFGKSSNVGTLMLAQRLGEDKFADYLERFGVGQPTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITTL QMAGIYQALANDGERIQPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVTQVDPTGVQQGTAPDASIEGYQ ISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFVVAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLSA ATEPIILQAQ
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=633, Percent_Identity=28.5939968404423, Blast_Score=207, Evalue=1e-54, Organism=Escherichia coli, GI1786854, Length=502, Percent_Identity=24.3027888446215, Blast_Score=102, Evalue=9e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 69771; Mature: 69639
Theoretical pI: Translated: 4.17; Mature: 4.17
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYV CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEE DPARRGSIVDREGNQMAYTMQARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYV CCCCCCCEECCCCCEEEEEEEECEEEECHHHHHHHHCCCCCEEEEEECCCCCCCHHEEEE TIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIKSHDQDVTGISSEEILDKLNA EEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC DSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFE CCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCEE ASNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQA CCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHH KANSGAENASAVVLDAKTAEVLAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSV HCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHH AKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDHGVVPYTTAGIFGKSSNVGTL HHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHH MLAQRLGEDKFADYLERFGVGQPTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITT HHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCCCCCCEEEE LQMAGIYQALANDGERIQPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVT HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCCCCCEEEEECHHHHHHHHHHHHHH QVDPTGVQQGTAPDASIEGYQISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFV HCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEE VAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLSAATEPIILQAQ EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEC >Mature Secondary Structure TYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYV CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEE DPARRGSIVDREGNQMAYTMQARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYV CCCCCCCEECCCCCEEEEEEEECEEEECHHHHHHHHCCCCCEEEEEECCCCCCCHHEEEE TIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIKSHDQDVTGISSEEILDKLNA EEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC DSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFE CCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCEE ASNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQA CCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHH KANSGAENASAVVLDAKTAEVLAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSV HCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHH AKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDHGVVPYTTAGIFGKSSNVGTL HHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHH MLAQRLGEDKFADYLERFGVGQPTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITT HHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCCCCCCEEEE LQMAGIYQALANDGERIQPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVT HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCCCCCEEEEECHHHHHHHHHHHHHH QVDPTGVQQGTAPDASIEGYQISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFV HCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEE VAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLSAATEPIILQAQ EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]