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The map label for this gene is 62390965

Identifier: 62390965

GI number: 62390965

Start: 2217035

End: 2218252

Strand: Reverse

Name: 62390965

Synonym: cg2337

Alternate gene names: NA

Gene position: 2218252-2217035 (Counterclockwise)

Preceding gene: 62390966

Following gene: 62390963

Centisome position: 67.57

GC content: 55.09

Gene sequence:

>1218_bases
TTGGATTTTTCAATGAGCCAGAACCGCATCAGGACCACTCACGTTGGTTCCTTGCCCCGTACCCCAGAGCTACTTGATGC
AAACATCAAGCGTTCTAACGGTGAGATTGGGGAGGAGGAATTCTTCCAGATTCTGCAGTCTTCTGTAGATGACGTGATCA
AGCGCCAGGTTGACCTGGGTATCGACATCCTTAACGAGGGCGAATACGGCCACGTCACCTCCGGTGCAGTTGACTTCGGT
GCATGGTGGAACTACTCCTTCACCCGCCTGGGCGGACTGACCATGACCGATACCGACCGTTGGGCAAGCCAGGAAGCAGT
GCGTTCCACCCCTGGCAACATCAAGCTGACCAGCTTCTCTGATCGTCGCGACCGCGCATTGTTCAGCGAAGCATACGAGG
ATCCAGTATCTGGCATCTTCACCGGTCGCGCTTCTGTGGGCAACCCAGAGTTCACCGGACCTATTACCTACATTGGCCAG
GAAGAAACTCAGACGGATGTTGATCTGCTGAAGAAGGGCATGAACGCAGCGGGAGCTACCGACGGCTTCGTTGCAGCACT
ATCCCCAGGATCTGCAGCTCGATTGACCAACAAGTTCTACGACACTGATGAAGAAGTCGTCGCAGCATGTGCTGATGCGC
TTTCCCAGGAATACAAGATCATCACCGATGCAGGTCTGACCGTTCAGCTCGACGCACCGGACTTGGCAGAAGCATGGGAT
CAGATCAACCCAGAGCCAAGCGTGAAGGATTACTTGGACTGGATCGGTACACGCATCGATGCCATCAACAGTGCAGTGAA
GGGCCTTCCAAAGGAACAGACCCGCCTGCACATCTGCTGGGGCTCTTGGCACGGACCACACGTCACTGACATCCCATTCG
GTGACATCATTGGTGAGATCCTGCGCGCAGAGGTCGGTGGCTTCTCCTTCGAAGGCGCATCTCCTCGTCACGCACACGAG
TGGCGTGTATGGGAAGAAAACAAGCTTCCTGAAGGCTCTGTTATCTACCCTGGTGTTGTGTCTCACTCCATCAACGCTGT
GGAGCACCCACGCCTGGTTGCTGATCGTATCGTTCAGTTCGCCAAGCTTGTTGGCCCTGAGAACGTCATTGCGTCCACTG
ACTGTGGTCTGGGCGGACGTCTGCATTCCCAGATCGCATGGGCAAAGCTGGAGTCCCTAGTAGAGGGCGCTCGCATTGCA
TCAAAGGAACTGTTCTAA

Upstream 100 bases:

>100_bases
AAACCCGAATGATGAATAAAATTCCGGGTGCAGTGACCGTAGGTGAGGTAAACGCGGTTAGAGTCGAATGAGAGTTTGAT
ACTTTCTTTCGACTTTTAGA

Downstream 100 bases:

>100_bases
GCTAGACAACGAGGGTTGCTAGTCTAAGCAGCAAAATGAGCGGCTGTTGTTCCTTCAGGAAAATTATCTGAAGGAACAAT
AGCCGCTCATTTTATGTCAG

Product: methionine synthase II (cobalamin-independent)

Products: tetrahydropteroyltri-L-glutamate; L-methionine

Alternate protein names: Methionine Synthase II; Methionine Synthase II- Like Protein; EpoxyalkaneCo M Transferase; Methyltransferase; Methionine Synthase Vitamin-B12 Independent Protein

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MDFSMSQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLGIDILNEGEYGHVTSGAVDFG
AWWNYSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFSDRRDRALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQ
EETQTDVDLLKKGMNAAGATDGFVAALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWD
QINPEPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEILRAEVGGFSFEGASPRHAHE
WRVWEENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQFAKLVGPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIA
SKELF

Sequences:

>Translated_405_residues
MDFSMSQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLGIDILNEGEYGHVTSGAVDFG
AWWNYSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFSDRRDRALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQ
EETQTDVDLLKKGMNAAGATDGFVAALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWD
QINPEPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEILRAEVGGFSFEGASPRHAHE
WRVWEENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQFAKLVGPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIA
SKELF
>Mature_405_residues
MDFSMSQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLGIDILNEGEYGHVTSGAVDFG
AWWNYSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFSDRRDRALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQ
EETQTDVDLLKKGMNAAGATDGFVAALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWD
QINPEPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEILRAEVGGFSFEGASPRHAHE
WRVWEENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQFAKLVGPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIA
SKELF

Specific function: Unknown

COG id: COG0620

COG function: function code E; Methionine synthase II (cobalamin-independent)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.14

Molecular weight: Translated: 44376; Mature: 44376

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSMSQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLG
CCCCCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
IDILNEGEYGHVTSGAVDFGAWWNYSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFS
CEEECCCCCCCEECCCEECCCCCCCCHHHHCCEEECCCHHHHHHHHHHCCCCCEEEEECC
DRRDRALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQEETQTDVDLLKKGMNAAGAT
CHHHHHHHHHHHHCHHHHEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCC
DGFVAALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWD
CCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEECCCCEEEECCCHHHHHHH
QINPEPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEI
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
LRAEVGGFSFEGASPRHAHEWRVWEENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQF
HHHHHCCEECCCCCCCCCCCCCEECCCCCCCCCEECCCHHHHCCCHHCCHHHHHHHHHHH
AKLVGPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIASKELF
HHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFSMSQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLG
CCCCCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
IDILNEGEYGHVTSGAVDFGAWWNYSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFS
CEEECCCCCCCEECCCEECCCCCCCCHHHHCCEEECCCHHHHHHHHHHCCCCCEEEEECC
DRRDRALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQEETQTDVDLLKKGMNAAGAT
CHHHHHHHHHHHHCHHHHEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCC
DGFVAALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWD
CCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEECCCCEEEECCCHHHHHHH
QINPEPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEI
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
LRAEVGGFSFEGASPRHAHEWRVWEENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQF
HHHHHCCEECCCCCCCCCCCCCEECCCCCCCCCEECCCHHHHCCCHHCCHHHHHHHHHHH
AKLVGPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIASKELF
HHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-methyltetrahydropteroyltri-L-glutamate; L-homocysteine

Specific reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA