Click here to switch to the map view.

The map label for this gene is rbsR [H]

Identifier: 62390882

GI number: 62390882

Start: 2126794

End: 2127777

Strand: Reverse

Name: rbsR [H]

Synonym: cg2242

Alternate gene names: 62390882

Gene position: 2127777-2126794 (Counterclockwise)

Preceding gene: 62390883

Following gene: 62390881

Centisome position: 64.82

GC content: 54.27

Gene sequence:

>984_bases
GTGGAGATGTCAGCAAAATCGAGCCTCAAGGAAGTTGCTGAGTTAGCTGGAGTCGGTTATGCCACAGCCTCGAGGGCACT
ATCTGGCAAGGGGTATGTGTCCCCGCAGACGCGGGAGAAAGTTCAGGCGGCGGCTAAAGAGCTGAACTATGTACCAAATC
AGCTGGCCAAGGCGTTGCGGGAACATCGCAGTGCCTTGGTGGGGGTCATTGTTCCGGATTTGTCCAATGAGTATTATTCG
GAATCGCTGCAGACTATTCAGCAGGATCTGAAAGCTGCTGGCTATCAAATGCTGGTTGCGGAGGCCAACAGTGTGCAGGC
GCAGGACGTGGTGATGGAATCGTTGATCTCGATTCAAGCTGCAGGAATTATCCACGTTCCAGTGGTCGGCTCAATTGCTC
CTGAAGGAATCCCCATGGTGCAGTTGACTCGTGGTGAATTGGGTCCTGGTTTCCCTCGGGTGTTGTGTGATGATGAGGCT
GGGTTTTTTCAGCTGACCGAGTCGGTGCTGGGCGGCAGCGGAATGAACATTGCTGCTTTGGTTGGTGAAGAATCACTTTC
CACCACGCAGGAACGAATGCGCGGTATTAGTCATGCGGCGTCGATATATGGGGCTGAGGTGACGTTCCATTTTGGCCACT
ATTCTGTCGAATCTGGCGAAGAGATGGCTCAGGTGGTGTTTAACAACGGCCTTCCCGATGCATTGATTGTGGCGTCTCCT
CGGCTGATGGCTGGGGTGATGCGTGCTTTTACTCGCCTGAATGTCCGCGTTCCCCACGATGTGGTGATTGGTGGTTATGA
CGATCCTGAGTGGTACAGCTTTGTCGGCGCGGGGATTACCACGTTTGTTCCACCGCATGAGGAGATGGGGAAAGAGGCCG
TGCGCTTGTTGGTAGATCTGATTGAAAATCCCGAACTTCCCACCGGCGATGTGGTTTTGCAGGGGCAGGTGATCCTTCGG
GGGTCGAGCACACATTCCGGGTAG

Upstream 100 bases:

>100_bases
CAATTGCTGGCGCGGTATCGATTACAATCTGGTTGGTTATCGGTGGTTTGTGGATGAATGTCATCGGACTCTGGTAATTG
AAAATTAAAGGTAAGGGGGT

Downstream 100 bases:

>100_bases
AATTGCCCAAATGTCATCAATTTCTCGAACGATTGCTCTCGAACTCGGCGTCAAAGATGAACAAGTCGAGGCCGCCATCA
AGCTCTTGGATGAAGGAAAC

Product: transcription regulation repressor, LACI family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MEMSAKSSLKEVAELAGVGYATASRALSGKGYVSPQTREKVQAAAKELNYVPNQLAKALREHRSALVGVIVPDLSNEYYS
ESLQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQAAGIIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVLCDDEA
GFFQLTESVLGGSGMNIAALVGEESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASP
RLMAGVMRAFTRLNVRVPHDVVIGGYDDPEWYSFVGAGITTFVPPHEEMGKEAVRLLVDLIENPELPTGDVVLQGQVILR
GSSTHSG

Sequences:

>Translated_327_residues
MEMSAKSSLKEVAELAGVGYATASRALSGKGYVSPQTREKVQAAAKELNYVPNQLAKALREHRSALVGVIVPDLSNEYYS
ESLQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQAAGIIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVLCDDEA
GFFQLTESVLGGSGMNIAALVGEESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASP
RLMAGVMRAFTRLNVRVPHDVVIGGYDDPEWYSFVGAGITTFVPPHEEMGKEAVRLLVDLIENPELPTGDVVLQGQVILR
GSSTHSG
>Mature_327_residues
MEMSAKSSLKEVAELAGVGYATASRALSGKGYVSPQTREKVQAAAKELNYVPNQLAKALREHRSALVGVIVPDLSNEYYS
ESLQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQAAGIIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVLCDDEA
GFFQLTESVLGGSGMNIAALVGEESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASP
RLMAGVMRAFTRLNVRVPHDVVIGGYDDPEWYSFVGAGITTFVPPHEEMGKEAVRLLVDLIENPELPTGDVVLQGQVILR
GSSTHSG

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=26.969696969697, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790194, Length=343, Percent_Identity=26.530612244898, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786268, Length=313, Percent_Identity=26.8370607028754, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786540, Length=304, Percent_Identity=29.9342105263158, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789068, Length=330, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787948, Length=332, Percent_Identity=24.3975903614458, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789202, Length=329, Percent_Identity=25.2279635258359, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=25.9938837920489, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994940, Length=298, Percent_Identity=26.1744966442953, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787906, Length=218, Percent_Identity=31.651376146789, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790715, Length=333, Percent_Identity=21.6216216216216, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=28.2894736842105, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 34897; Mature: 34897

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2 ; PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMSAKSSLKEVAELAGVGYATASRALSGKGYVSPQTREKVQAAAKELNYVPNQLAKALR
CCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
EHRSALVGVIVPDLSNEYYSESLQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQA
HHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
AGIIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVLCDDEAGFFQLTESVLGGSGMNIAAL
CCEEEECCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCEEEEE
VGEESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASP
ECCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCHHHHHHHHHCCCCCCCEEECCC
RLMAGVMRAFTRLNVRVPHDVVIGGYDDPEWYSFVGAGITTFVPPHEEMGKEAVRLLVDL
HHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHH
IENPELPTGDVVLQGQVILRGSSTHSG
HHCCCCCCCCEEEECEEEEECCCCCCC
>Mature Secondary Structure
MEMSAKSSLKEVAELAGVGYATASRALSGKGYVSPQTREKVQAAAKELNYVPNQLAKALR
CCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
EHRSALVGVIVPDLSNEYYSESLQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQA
HHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
AGIIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVLCDDEAGFFQLTESVLGGSGMNIAAL
CCEEEECCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCEEEEE
VGEESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASP
ECCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCHHHHHHHHHCCCCCCCEEECCC
RLMAGVMRAFTRLNVRVPHDVVIGGYDDPEWYSFVGAGITTFVPPHEEMGKEAVRLLVDL
HHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHH
IENPELPTGDVVLQGQVILRGSSTHSG
HHCCCCCCCCEEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]