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The map label for this gene is hflX [H]

Identifier: 62390780

GI number: 62390780

Start: 2018696

End: 2020225

Strand: Reverse

Name: hflX [H]

Synonym: cg2126

Alternate gene names: 62390780

Gene position: 2020225-2018696 (Counterclockwise)

Preceding gene: 62390783

Following gene: 62390779

Centisome position: 61.54

GC content: 56.14

Gene sequence:

>1530_bases
ATGGATGAAAAGAAAAACTTAAGTCATGATGAACTTCTCGCTCAGGCCTTCCGCGGTCACAAAAATACCGTGCGCCCAGG
ATCTGACGAGACCTCAGGTTTTGATCTCAGTGGTTTTATCCGAGCTGAAGAACCATCAACTGGTGATCTCGACCTAGAGG
CCCGCGATGCCCAACGTCGCCGGGACACCGAAATCCACGCTGATGAAGCAGCAGATGGCTACGAGGTTGAGTACCGAAAG
CTGCGACTTGAGCGCGTTATCTTAGTGGGCGTGTGGACCGAAGGTACCACCGCAGAAATTGACGCCAGCCTTGCGGAACT
TGCAGCGTTGGCTGATACCGCCGGCGCTGAGGTTATTGAAACGCTGTACCAAAAGCGCGATAAACCAGATCCTGGAACCT
ACATTGGTTCCGGCAAGGTTCGGGAGTTAAAGGAGATCATCGAAGCCACTAGTGCAGATACCGTGGTGTGCGATGGTGAA
CTTAGCCCTTCCCAGCTCGTGGCATTAGAGCGCGAACTTGATATCAAGGTCATTGACCGCACCATGCTGATTCTGGATAT
CTTCGCCCAGCACGCTAAATCGCGCGAAGGTAAAGCCCAAGTCGCGTTGGCGCAGATGGAATACCTGATTAGCCGTGTGC
GTGGTTGGGGTGGAAACCTCTCCAGGCAGGCCGGTGGTCGTGCAGGTTCTAATGGTGGTGTGGGTCTGCGTGGTCCAGGT
GAAACCAAAATTGAAGCAGACCGCCGTCGTCTTCGATCGGATATGGCTCGCCTGCGCAGGGAACTTTCGGGGCTGGATAC
GTCGAGAAGCATTAAAAGAGCGCAACGCGCAGCCTCCCTGGTGCCGCAGATCGCCATCGCTGGCTACACGAACGCCGGCA
AATCTTCGCTGATTAACGCGATGACCGGCGCGGGTGTGCTGGTGGAGAACGCGCTGTTCGCCACGCTTGATCCAACAACC
AGAAAAGCCGAGCTTGCCGACGGCCGACACGTCGTGTTCACGGACACCGTCGGCTTTGTGCGACACCTGCCGACCTCTCT
GGTTGAGGCGTTCAAATCTACGCTGGAAGAAGTCGTGGAGGCGGACCTCATGCTGCACGTGGTGGATGGATCCGATCCGT
TCCCGCTGAAGCAGATCGACGCTGTGAACACCGTGATTAGCGATATTGTGCGATCCACCGGTGCGGTGCCACCACCAGAG
ATCATCGTGGTGAACAAAATTGACCAAGCTGATCCGCTGACGCTGGCAGAACTACGCCACGCCGTCGACGATGTGGTGTT
TGTCTCTGCGCTGACAGGGGAGGGAATTAAGGAGCTGGAAGCTCGCATCGAACTATTCCTCAACTCCAGGGACGCGCACC
TACTGCTGAAAATCCCGTTCACCCGTGGCGATATTGTGTCCCGCCTGCACCAGCATGGCACCGTTCTCAGCGAAGACTAC
GCCGAAGACGGCACCTTGATGGATGTGCGTATCCCCACCCAATTGGCCCAAGAGCTGCAGAGTTACGTTGTAGAACCCAC
CTCTGCCTAA

Upstream 100 bases:

>100_bases
AATAGAGCGCTCAATTTAGGTGTTTATGGTGGCTTGATCGCTCACGGCGTTGCCCGACACCTAGCCTTGGCGACAGCAGA
CGTGAAACAATAGATAAACA

Downstream 100 bases:

>100_bases
CTGTCGATTTCCCAAGAGCCCCCTTGGGAGTCGATAATTAGTGCTCGTGACTTCAACATGGGGATGGACCGTCCACGGAG
ACGGCAAAAAGATCGAACCC

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MDEKKNLSHDELLAQAFRGHKNTVRPGSDETSGFDLSGFIRAEEPSTGDLDLEARDAQRRRDTEIHADEAADGYEVEYRK
LRLERVILVGVWTEGTTAEIDASLAELAALADTAGAEVIETLYQKRDKPDPGTYIGSGKVRELKEIIEATSADTVVCDGE
LSPSQLVALERELDIKVIDRTMLILDIFAQHAKSREGKAQVALAQMEYLISRVRGWGGNLSRQAGGRAGSNGGVGLRGPG
ETKIEADRRRLRSDMARLRRELSGLDTSRSIKRAQRAASLVPQIAIAGYTNAGKSSLINAMTGAGVLVENALFATLDPTT
RKAELADGRHVVFTDTVGFVRHLPTSLVEAFKSTLEEVVEADLMLHVVDGSDPFPLKQIDAVNTVISDIVRSTGAVPPPE
IIVVNKIDQADPLTLAELRHAVDDVVFVSALTGEGIKELEARIELFLNSRDAHLLLKIPFTRGDIVSRLHQHGTVLSEDY
AEDGTLMDVRIPTQLAQELQSYVVEPTSA

Sequences:

>Translated_509_residues
MDEKKNLSHDELLAQAFRGHKNTVRPGSDETSGFDLSGFIRAEEPSTGDLDLEARDAQRRRDTEIHADEAADGYEVEYRK
LRLERVILVGVWTEGTTAEIDASLAELAALADTAGAEVIETLYQKRDKPDPGTYIGSGKVRELKEIIEATSADTVVCDGE
LSPSQLVALERELDIKVIDRTMLILDIFAQHAKSREGKAQVALAQMEYLISRVRGWGGNLSRQAGGRAGSNGGVGLRGPG
ETKIEADRRRLRSDMARLRRELSGLDTSRSIKRAQRAASLVPQIAIAGYTNAGKSSLINAMTGAGVLVENALFATLDPTT
RKAELADGRHVVFTDTVGFVRHLPTSLVEAFKSTLEEVVEADLMLHVVDGSDPFPLKQIDAVNTVISDIVRSTGAVPPPE
IIVVNKIDQADPLTLAELRHAVDDVVFVSALTGEGIKELEARIELFLNSRDAHLLLKIPFTRGDIVSRLHQHGTVLSEDY
AEDGTLMDVRIPTQLAQELQSYVVEPTSA
>Mature_509_residues
MDEKKNLSHDELLAQAFRGHKNTVRPGSDETSGFDLSGFIRAEEPSTGDLDLEARDAQRRRDTEIHADEAADGYEVEYRK
LRLERVILVGVWTEGTTAEIDASLAELAALADTAGAEVIETLYQKRDKPDPGTYIGSGKVRELKEIIEATSADTVVCDGE
LSPSQLVALERELDIKVIDRTMLILDIFAQHAKSREGKAQVALAQMEYLISRVRGWGGNLSRQAGGRAGSNGGVGLRGPG
ETKIEADRRRLRSDMARLRRELSGLDTSRSIKRAQRAASLVPQIAIAGYTNAGKSSLINAMTGAGVLVENALFATLDPTT
RKAELADGRHVVFTDTVGFVRHLPTSLVEAFKSTLEEVVEADLMLHVVDGSDPFPLKQIDAVNTVISDIVRSTGAVPPPE
IIVVNKIDQADPLTLAELRHAVDDVVFVSALTGEGIKELEARIELFLNSRDAHLLLKIPFTRGDIVSRLHQHGTVLSEDY
AEDGTLMDVRIPTQLAQELQSYVVEPTSA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=282, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI310124269, Length=260, Percent_Identity=34.2307692307692, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124267, Length=260, Percent_Identity=34.2307692307692, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124171, Length=260, Percent_Identity=34.2307692307692, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124169, Length=260, Percent_Identity=34.2307692307692, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310133116, Length=279, Percent_Identity=32.9749103942652, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI24308117, Length=173, Percent_Identity=30.635838150289, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790615, Length=419, Percent_Identity=41.0501193317422, Blast_Score=279, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=283, Percent_Identity=34.2756183745583, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24650079, Length=324, Percent_Identity=34.5679012345679, Blast_Score=135, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 55468; Mature: 55468

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEKKNLSHDELLAQAFRGHKNTVRPGSDETSGFDLSGFIRAEEPSTGDLDLEARDAQRR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
RDTEIHADEAADGYEVEYRKLRLERVILVGVWTEGTTAEIDASLAELAALADTAGAEVIE
HCCCCCCCCCCCCCHHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLYQKRDKPDPGTYIGSGKVRELKEIIEATSADTVVCDGELSPSQLVALERELDIKVIDR
HHHHHCCCCCCCCEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCHHHHHH
TMLILDIFAQHAKSREGKAQVALAQMEYLISRVRGWGGNLSRQAGGRAGSNGGVGLRGPG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCC
ETKIEADRRRLRSDMARLRRELSGLDTSRSIKRAQRAASLVPQIAIAGYTNAGKSSLINA
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHH
MTGAGVLVENALFATLDPTTRKAELADGRHVVFTDTVGFVRHLPTSLVEAFKSTLEEVVE
HHCCCHHHHCCEEEECCCCCCCHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ADLMLHVVDGSDPFPLKQIDAVNTVISDIVRSTGAVPPPEIIVVNKIDQADPLTLAELRH
HCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHH
AVDDVVFVSALTGEGIKELEARIELFLNSRDAHLLLKIPFTRGDIVSRLHQHGTVLSEDY
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHH
AEDGTLMDVRIPTQLAQELQSYVVEPTSA
CCCCCEEEEECHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDEKKNLSHDELLAQAFRGHKNTVRPGSDETSGFDLSGFIRAEEPSTGDLDLEARDAQRR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
RDTEIHADEAADGYEVEYRKLRLERVILVGVWTEGTTAEIDASLAELAALADTAGAEVIE
HCCCCCCCCCCCCCHHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLYQKRDKPDPGTYIGSGKVRELKEIIEATSADTVVCDGELSPSQLVALERELDIKVIDR
HHHHHCCCCCCCCEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCHHHHHH
TMLILDIFAQHAKSREGKAQVALAQMEYLISRVRGWGGNLSRQAGGRAGSNGGVGLRGPG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCC
ETKIEADRRRLRSDMARLRRELSGLDTSRSIKRAQRAASLVPQIAIAGYTNAGKSSLINA
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHH
MTGAGVLVENALFATLDPTTRKAELADGRHVVFTDTVGFVRHLPTSLVEAFKSTLEEVVE
HHCCCHHHHCCEEEECCCCCCCHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ADLMLHVVDGSDPFPLKQIDAVNTVISDIVRSTGAVPPPEIIVVNKIDQADPLTLAELRH
HCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHH
AVDDVVFVSALTGEGIKELEARIELFLNSRDAHLLLKIPFTRGDIVSRLHQHGTVLSEDY
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHH
AEDGTLMDVRIPTQLAQELQSYVVEPTSA
CCCCCEEEEECHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]