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The map label for this gene is ygcA [C]

Identifier: 62390742

GI number: 62390742

Start: 1975507

End: 1976745

Strand: Reverse

Name: ygcA [C]

Synonym: cg2084

Alternate gene names: 62390742

Gene position: 1976745-1975507 (Counterclockwise)

Preceding gene: 62390743

Following gene: 62390741

Centisome position: 60.22

GC content: 57.14

Gene sequence:

>1239_bases
ATGACTGACACCGTCGAACTCGCCAAAGGCGACATCATCTCCGTTGAGGTGCTCAGGCCGGCTCACGGCGGCGAAGGCAT
CGGACACCACGATGGCCGCGTCATCTTCGTGAAAGGTGGCATTCCCGGGGATGTCGTGGATGTAGAAATCGCACAGTTGA
AGAAGAAATGGGCACGCGGTGAAGTGGTTAAGGTAACCACCGCGTCTGCTGATCGTGTCGATTCCCGTTGCCCAGCAGCG
GCAGCAGGTGCTGGTTGCTGTGACTATGCAGAACTCAACCCAACTGTGGAGCTTGAGATCAAGTCCCGCGTGCTTCGTGA
TCAGTTGGAGCGCATCGGTGGAATCGATGAGCTTCCTGAATTTGAGCTTCAAGATCTGGAGCCAACAGCTGGTTGGCGTA
CCCGCGTTCGCCTCGGCGTTGATGCGTCTGGTCGTGCCGGGTTCCGCAAGCTGAAGTCCAATGAGTTGGTTACTGAGGTT
GCGTGTTCTCAGGTTGTGCCAGAGCTTCTTGAGGGCCTTGTGGGTGAGGGCGCTCGTCGTTTCACCCCTGGCGTGGAGAT
CATTGCAGCTATTGATGATGCGGGTCAGCGCCACGTTGTGGAATCCCGTAAGGCTCCTCGTGGTCGTCGTACTGAAACTG
TGTTGAAGGTGCTGGAAGGCACTGGCGAGGTGGAGCAGAAGGTAGGCGATTACACCTGGAAGTTCCCAGTTTCTTCCTTC
TGGCAGGCGCACACCAAGGCCCCTGCGGCGTATTCAGAGTTCATCGCCGAAGCGTTAACCGGATTGGAACTGGTTGACGT
CGATAAGCGTGGCCCTGTTGCGTGGGACCTTTATGGCGGCGTCGGCCTGTTCGCGCCGATTATCACCAGCAAGCTGCAGG
CAGCTGTCCACTCTGTGGAGCTGTCCCCAGGTTCAGCGGAGGCTGGCGAAGAGGCGTTGGCTGGTTTGCCTGTCACTTTC
CACACTGGTCGGGTAGAGGGCATGGCGTCCCAGCTGCCTTCGCCAAACGTGGTTGTTTTGGATCCTCCTCGCACCGGTGC
AGGCAGTGACGTGTTGAAGAGCATCGCGGAGGCTAAGCCTCAGCTGGTTATCCACATTGGTTGTGACCCGGCGACTTTCG
CTCGCGACGTTGCCGATTGGAAGCTCAACGGCTACGAAATGGATCAATTGGCTGTTTTTAACGCGTTCCCTGGAACTCAC
CACTTTGAGACGATTGGTGTATTTGTCCGCGTTTCCTAA

Upstream 100 bases:

>100_bases
GGAAATACCCCCAACGCAGAGTAGGGTTAAACTCTTTGCGCTGTCCCGCTCCAAGTAACGGGACAGAAACTTTTTCAAGT
GAAACGAGGACTACACTCAC

Downstream 100 bases:

>100_bases
GGCGGATTAAGCCTTGGCTATCGAGACAGAGTAATATAGCTCCAACACCGCAGGTGCACATTTGTTTTGTCACCTGCACA
AAAGTGTCGCCAGCCCGATA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARGEVVKVTTASADRVDSRCPAA
AAGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPEFELQDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEV
ACSQVVPELLEGLVGEGARRFTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSF
WQAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVELSPGSAEAGEEALAGLPVTF
HTGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKPQLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTH
HFETIGVFVRVS

Sequences:

>Translated_412_residues
MTDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARGEVVKVTTASADRVDSRCPAA
AAGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPEFELQDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEV
ACSQVVPELLEGLVGEGARRFTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSF
WQAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVELSPGSAEAGEEALAGLPVTF
HTGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKPQLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTH
HFETIGVFVRVS
>Mature_411_residues
TDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARGEVVKVTTASADRVDSRCPAAA
AGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPEFELQDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEVA
CSQVVPELLEGLVGEGARRFTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSFW
QAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVELSPGSAEAGEEALAGLPVTFH
TGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKPQLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTHH
FETIGVFVRVS

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain

Homologues:

Organism=Escherichia coli, GI1789148, Length=443, Percent_Identity=27.313769751693, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787083, Length=208, Percent_Identity=23.5576923076923, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1903_CORGL (Q6M4B7)

Other databases:

- EMBL:   BA000036
- EMBL:   BX927153
- RefSeq:   NP_601109.1
- RefSeq:   YP_226144.1
- ProteinModelPortal:   Q6M4B7
- SMR:   Q6M4B7
- World-2DPAGE:   0001:Q6M4B7
- PRIDE:   Q6M4B7
- GeneID:   1019860
- GeneID:   3345033
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2084
- KEGG:   cgl:NCgl1828
- HOGENOM:   HBG690163
- OMA:   AWRPGDF
- PhylomeDB:   Q6M4B7
- ProtClustDB:   CLSK633522
- BioCyc:   CGLU196627:CG2084-MONOMER
- InterPro:   IPR016027
- InterPro:   IPR002792
- InterPro:   IPR010280

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 44121; Mature: 43989

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50926 TRAM; PS01230 TRMA_1; PS01231 TRMA_2

Important sites: ACT_SITE 368-368 BINDING 242-242 BINDING 278-278 BINDING 300-300 BINDING 341-341

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARG
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCC
EVVKVTTASADRVDSRCPAAAAGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPE
CEEEEEECCCHHHHCCCCCHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCC
FELQDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEVACSQVVPELLEGLVGEGARR
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
FTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSF
CCCCEEEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCEEEECCHHHH
WQAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVE
HHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEE
LSPGSAEAGEEALAGLPVTFHTGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKP
CCCCCCCCCHHHHHCCCEEEECCCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCC
QLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTHHFETIGVFVRVS
EEEEEECCCHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
TDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARG
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCC
EVVKVTTASADRVDSRCPAAAAGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPE
CEEEEEECCCHHHHCCCCCHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCC
FELQDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEVACSQVVPELLEGLVGEGARR
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
FTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSF
CCCCEEEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCEEEECCHHHH
WQAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVE
HHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEE
LSPGSAEAGEEALAGLPVTFHTGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKP
CCCCCCCCCHHHHHCCCEEEECCCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCC
QLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTHHFETIGVFVRVS
EEEEEECCCHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626