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The map label for this gene is fmt

Identifier: 62390482

GI number: 62390482

Start: 1696964

End: 1697911

Strand: Reverse

Name: fmt

Synonym: cg1803

Alternate gene names: 62390482

Gene position: 1697911-1696964 (Counterclockwise)

Preceding gene: 62390483

Following gene: 62390481

Centisome position: 51.72

GC content: 58.97

Gene sequence:

>948_bases
ATGCGCCTAGTTTTTGCCGGAACTCCGGAACCTGCAGTGGTGGCACTGCAAAAGCTCATTGATTCCGATCATGAGGTCGT
CGCTGTGTTGACGCAACCAGATGCACGTCGCGGCCGTGGTCGTACGCTGCATCCTTCAGCTGTCGCGGAGCTTGCACAGC
AGCACGGTATTGAGGTGTTAAAGCCCACCTCCCTGAAGGCTGATACGGAAGATGGCCAAGCAATCCGTCAGCGCTTGGCT
GAGCTTGCCCCCGATTGCTTGCCGGTGGTGGCATACGGACAGCTGATCACCAAGGATTTGCTGGATGTTGCGCCACACGG
TTGGGTGAATCTGCACTTTTCTTTGCTTCCTGCATGGCGTGGGGCGGCGCCGGTTCAGGCGTCGATCCGTGAAGGCGATC
AGATCACTGGTGCCACGACCTTCCGCATTGATGAGGGCCTGGATACCGGCGTGATTTTGTCCACCATCGAGGACACAATT
CAGCCCACCGATACTGCGGATGATCTTCTTACTCGCCTGGCGTATTCAGGCGGTGACCTGCTGGTTGAGACCATGACTGG
CCTGGAGCAGGGCACAATCACCCCGCGCGCCCAGGAAGGCGAGGCCACGTACGCCTCAAAAATCACCACCCAGGACGCGC
AGATTGATTGGTCGAAGCCCGCCGAGGTCATCGACCGCCACATCAGGGCACATACCCCAGGACCTGGCGCATGGACCACG
CTTGTCGACGCCCGCCTCAAGGTCGGGCCCATCAGCCACTCAGGCGAGGTCGAAGTAGCAGCGGACTTGGCGCCTGGCGC
CATCCTGGCGCAAAAGAACTCCGTGGTGGTCGGAACGGGCACCACACCAATTGTTCTGGGCAATATCCAACCCCCGGGAA
AGAAAATGATGAATGCAGCAGACTGGGCGCGTGGTGTCCAACTTGATCAGGAAGCGAAATTCCAATGA

Upstream 100 bases:

>100_bases
CTGTTTTTGAAGCGCCTTGATCCAGCTGAACGTAAAGCAGCCATGGGCGTTATTCGCGCGTCTGCATGGTTTAACAAATA
ATGAGTGGAAAGGGCACTTC

Downstream 100 bases:

>100_bases
GCCTAGAAAAATCCGGCGGATTCCGCTCCAGGACTCCAAAAGCGCAGCAGGAACCTGCTAAGCAGAAGCCGCAGGCGCGT
AAATCTCCGTCAAAGAAGGC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MRLVFAGTPEPAVVALQKLIDSDHEVVAVLTQPDARRGRGRTLHPSAVAELAQQHGIEVLKPTSLKADTEDGQAIRQRLA
ELAPDCLPVVAYGQLITKDLLDVAPHGWVNLHFSLLPAWRGAAPVQASIREGDQITGATTFRIDEGLDTGVILSTIEDTI
QPTDTADDLLTRLAYSGGDLLVETMTGLEQGTITPRAQEGEATYASKITTQDAQIDWSKPAEVIDRHIRAHTPGPGAWTT
LVDARLKVGPISHSGEVEVAADLAPGAILAQKNSVVVGTGTTPIVLGNIQPPGKKMMNAADWARGVQLDQEAKFQ

Sequences:

>Translated_315_residues
MRLVFAGTPEPAVVALQKLIDSDHEVVAVLTQPDARRGRGRTLHPSAVAELAQQHGIEVLKPTSLKADTEDGQAIRQRLA
ELAPDCLPVVAYGQLITKDLLDVAPHGWVNLHFSLLPAWRGAAPVQASIREGDQITGATTFRIDEGLDTGVILSTIEDTI
QPTDTADDLLTRLAYSGGDLLVETMTGLEQGTITPRAQEGEATYASKITTQDAQIDWSKPAEVIDRHIRAHTPGPGAWTT
LVDARLKVGPISHSGEVEVAADLAPGAILAQKNSVVVGTGTTPIVLGNIQPPGKKMMNAADWARGVQLDQEAKFQ
>Mature_315_residues
MRLVFAGTPEPAVVALQKLIDSDHEVVAVLTQPDARRGRGRTLHPSAVAELAQQHGIEVLKPTSLKADTEDGQAIRQRLA
ELAPDCLPVVAYGQLITKDLLDVAPHGWVNLHFSLLPAWRGAAPVQASIREGDQITGATTFRIDEGLDTGVILSTIEDTI
QPTDTADDLLTRLAYSGGDLLVETMTGLEQGTITPRAQEGEATYASKITTQDAQIDWSKPAEVIDRHIRAHTPGPGAWTT
LVDARLKVGPISHSGEVEVAADLAPGAILAQKNSVVVGTGTTPIVLGNIQPPGKKMMNAADWARGVQLDQEAKFQ

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family

Homologues:

Organism=Homo sapiens, GI238814322, Length=294, Percent_Identity=32.312925170068, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI21614513, Length=297, Percent_Identity=30.3030303030303, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI164663775, Length=145, Percent_Identity=35.1724137931034, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789683, Length=303, Percent_Identity=41.9141914191419, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1788589, Length=291, Percent_Identity=30.9278350515464, Blast_Score=121, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI133930964, Length=255, Percent_Identity=31.3725490196078, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550868, Length=231, Percent_Identity=30.7359307359307, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571984, Length=231, Percent_Identity=30.7359307359307, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24585660, Length=326, Percent_Identity=25.7668711656442, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FMT_CORGB (A4QEH4)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138542.1
- ProteinModelPortal:   A4QEH4
- SMR:   A4QEH4
- STRING:   A4QEH4
- GeneID:   4992895
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1648
- eggNOG:   COG0223
- HOGENOM:   HBG571560
- OMA:   IMQMDEG
- ProtClustDB:   PRK00005
- HAMAP:   MF_00182
- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- PANTHER:   PTHR11138
- TIGRFAMs:   TIGR00460

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.9

Molecular weight: Translated: 33590; Mature: 33590

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVFAGTPEPAVVALQKLIDSDHEVVAVLTQPDARRGRGRTLHPSAVAELAQQHGIEVL
CEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEE
KPTSLKADTEDGQAIRQRLAELAPDCLPVVAYGQLITKDLLDVAPHGWVNLHFSLLPAWR
CCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
GAAPVQASIREGDQITGATTFRIDEGLDTGVILSTIEDTIQPTDTADDLLTRLAYSGGDL
CCCCCHHHHCCCCEECCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
LVETMTGLEQGTITPRAQEGEATYASKITTQDAQIDWSKPAEVIDRHIRAHTPGPGAWTT
EEHHHHCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHH
LVDARLKVGPISHSGEVEVAADLAPGAILAQKNSVVVGTGTTPIVLGNIQPPGKKMMNAA
HHHCEEEECCCCCCCCEEEEECCCCCEEEEECCCEEEECCCCCEEECCCCCCHHHHHHHH
DWARGVQLDQEAKFQ
HHHHCCCCCHHCCCC
>Mature Secondary Structure
MRLVFAGTPEPAVVALQKLIDSDHEVVAVLTQPDARRGRGRTLHPSAVAELAQQHGIEVL
CEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEE
KPTSLKADTEDGQAIRQRLAELAPDCLPVVAYGQLITKDLLDVAPHGWVNLHFSLLPAWR
CCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
GAAPVQASIREGDQITGATTFRIDEGLDTGVILSTIEDTIQPTDTADDLLTRLAYSGGDL
CCCCCHHHHCCCCEECCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
LVETMTGLEQGTITPRAQEGEATYASKITTQDAQIDWSKPAEVIDRHIRAHTPGPGAWTT
EEHHHHCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHH
LVDARLKVGPISHSGEVEVAADLAPGAILAQKNSVVVGTGTTPIVLGNIQPPGKKMMNAA
HHHCEEEECCCCCCCCEEEEECCCCCEEEEECCCEEEECCCCCEEECCCCCCHHHHHHHH
DWARGVQLDQEAKFQ
HHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA