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The map label for this gene is fmu [C]

Identifier: 62390481

GI number: 62390481

Start: 1695432

End: 1696967

Strand: Reverse

Name: fmu [C]

Synonym: cg1802

Alternate gene names: 62390481

Gene position: 1696967-1695432 (Counterclockwise)

Preceding gene: 62390482

Following gene: 62390480

Centisome position: 51.69

GC content: 58.59

Gene sequence:

>1536_bases
ATGAGCCTAGAAAAATCCGGCGGATTCCGCTCCAGGACTCCAAAAGCGCAGCAGGAACCTGCTAAGCAGAAGCCGCAGGC
GCGTAAATCTCCGTCAAAGAAGGCCCCGGCTCGGGGGCAGGGGCAGAGTCAGGGGCAGCGCCAGGGCCAAAGCAGTGGCA
AAGGCGGCGGAAACCGCAAGCCCCCTGCGCAGGCCAGGGAAGTGAGGGCTCTGGGCGTCGATAAGCCGAGAGAAATTGCG
TTTGAGGTGCTTGATCGTGTGCGTACCGGTGAGGCGTATGCCAACTTGGTGTTGCCACGACTGCTGAGCAAGCACAATCT
TTCTGGCCGTGACGCGGCCTTTGCTACGGAAATTACCTACGGCACCTTGCGTAATGTCGGCTTGCTGGATGAGGTCATTA
AGGCTGCATCTGGGCGTGAACTGTCTGATATTGATCCAGAGGTTTTGGACGTGCTGCGTTTGGGCGCGTACCAGGTGATG
TTTACCCGCGTGGAGGATCACGCTGCGGTCGATACTTCAGTAAAGATGGTCGGTGGGCTGAAGAAATTCCAGGCCACTGG
TTTTGCCAATGCAATTTTGCGCAACATCACGCGCAAGGAACCAGAGCAGTGGTTGAAGGAATTGGAGCCCGCGGAAGAGT
TGGCTCGCGTTGCGTTCCGTACTGCGCACCCACGCTGGATTGCGCAGAGTTTCTCACAGGTGCTCCCGGCAGATGAGTTG
GAAGCAGCGCTTGCTGCGGACTCTGAGCGCCCAGTGGTGCACTTGGTGGCTCGCCCAGGTGAGATCAGTGCAGAGGAATT
GGCGCTGATCACCGGTGGTGACGAGGGCAAGTATTCCCCATACGCGGTGTACCTCGAGGGTGGCGACCCGGGTGATATTG
AGCCAGTGAAGGATGGTCTTGCAGCAGTGCAAGATGAGGGTTCTCAGCTGATTGCTCGCGCCTTGGTGGAAATCCCCGTG
GAGGGCACCGATGCCGGCCGTTGGCTGGATATGTGTGCAGGTCCTGGCGGTAAAGCGGCGCTCATTGGTGCGTTGGCTCG
CATGGATCGTGCCACCGTTGATGCCGTGGAGGTCTCTGATCACCGTGCCCGACTGATTGAAAAGTCCGTGCGTGGTTTGC
CCGTCAAGGTTCATGTGGGCGATGGCCGCACCATCAACTTGACCGGTGGTTACGATCGTGCGCTAGTCGATGCGCCGTGT
TCTGGTTTGGGTGCACTGCGTCGTCGCCCTGAGGCGCGTTGGCGCAAGCAGGAAAGCGACATTGTTGAGCTCAACACCCT
GCAGTACGAGCTGCTTGAATCCGCTGTGAACAAGGTGCGTTCCGGTGGCGTGATTGTGTACTCCACATGTTCACCTGATC
TGCGTGAAACCCGCGGAATCGTGGACAAGGCACTGGGGGCTCTGGAGATCGAAGAGCTTGAGGCTGCGGAGTTCATGCCA
GGCATGACCGATACCGGCGATGAGAAATCAGTGCAGATGTGGCCACACCGCCACGGCACCGATGCGATGTTTGTGGCAGT
GCTGCGAAAGAAGTAG

Upstream 100 bases:

>100_bases
CACCAATTGTTCTGGGCAATATCCAACCCCCGGGAAAGAAAATGATGAATGCAGCAGACTGGGCGCGTGGTGTCCAACTT
GATCAGGAAGCGAAATTCCA

Downstream 100 bases:

>100_bases
ACCTGTGAGCTAAGTGGGGTAGACAAGAGGGCTATGATTTAGGGCATGGCACAACGTACTCCACTAATCGCCCCATCCAT
TCTTGCTGCTGATTTCTCCC

Product: 16S rRNA M(5)C 967 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MSLEKSGGFRSRTPKAQQEPAKQKPQARKSPSKKAPARGQGQSQGQRQGQSSGKGGGNRKPPAQAREVRALGVDKPREIA
FEVLDRVRTGEAYANLVLPRLLSKHNLSGRDAAFATEITYGTLRNVGLLDEVIKAASGRELSDIDPEVLDVLRLGAYQVM
FTRVEDHAAVDTSVKMVGGLKKFQATGFANAILRNITRKEPEQWLKELEPAEELARVAFRTAHPRWIAQSFSQVLPADEL
EAALAADSERPVVHLVARPGEISAEELALITGGDEGKYSPYAVYLEGGDPGDIEPVKDGLAAVQDEGSQLIARALVEIPV
EGTDAGRWLDMCAGPGGKAALIGALARMDRATVDAVEVSDHRARLIEKSVRGLPVKVHVGDGRTINLTGGYDRALVDAPC
SGLGALRRRPEARWRKQESDIVELNTLQYELLESAVNKVRSGGVIVYSTCSPDLRETRGIVDKALGALEIEELEAAEFMP
GMTDTGDEKSVQMWPHRHGTDAMFVAVLRKK

Sequences:

>Translated_511_residues
MSLEKSGGFRSRTPKAQQEPAKQKPQARKSPSKKAPARGQGQSQGQRQGQSSGKGGGNRKPPAQAREVRALGVDKPREIA
FEVLDRVRTGEAYANLVLPRLLSKHNLSGRDAAFATEITYGTLRNVGLLDEVIKAASGRELSDIDPEVLDVLRLGAYQVM
FTRVEDHAAVDTSVKMVGGLKKFQATGFANAILRNITRKEPEQWLKELEPAEELARVAFRTAHPRWIAQSFSQVLPADEL
EAALAADSERPVVHLVARPGEISAEELALITGGDEGKYSPYAVYLEGGDPGDIEPVKDGLAAVQDEGSQLIARALVEIPV
EGTDAGRWLDMCAGPGGKAALIGALARMDRATVDAVEVSDHRARLIEKSVRGLPVKVHVGDGRTINLTGGYDRALVDAPC
SGLGALRRRPEARWRKQESDIVELNTLQYELLESAVNKVRSGGVIVYSTCSPDLRETRGIVDKALGALEIEELEAAEFMP
GMTDTGDEKSVQMWPHRHGTDAMFVAVLRKK
>Mature_510_residues
SLEKSGGFRSRTPKAQQEPAKQKPQARKSPSKKAPARGQGQSQGQRQGQSSGKGGGNRKPPAQAREVRALGVDKPREIAF
EVLDRVRTGEAYANLVLPRLLSKHNLSGRDAAFATEITYGTLRNVGLLDEVIKAASGRELSDIDPEVLDVLRLGAYQVMF
TRVEDHAAVDTSVKMVGGLKKFQATGFANAILRNITRKEPEQWLKELEPAEELARVAFRTAHPRWIAQSFSQVLPADELE
AALAADSERPVVHLVARPGEISAEELALITGGDEGKYSPYAVYLEGGDPGDIEPVKDGLAAVQDEGSQLIARALVEIPVE
GTDAGRWLDMCAGPGGKAALIGALARMDRATVDAVEVSDHRARLIEKSVRGLPVKVHVGDGRTINLTGGYDRALVDAPCS
GLGALRRRPEARWRKQESDIVELNTLQYELLESAVNKVRSGGVIVYSTCSPDLRETRGIVDKALGALEIEELEAAEFMPG
MTDTGDEKSVQMWPHRHGTDAMFVAVLRKK

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=206, Percent_Identity=31.5533980582524, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI76150623, Length=206, Percent_Identity=31.5533980582524, Blast_Score=103, Evalue=5e-22,
Organism=Escherichia coli, GI2367212, Length=437, Percent_Identity=31.1212814645309, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081985, Length=223, Percent_Identity=30.4932735426009, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536757, Length=211, Percent_Identity=29.3838862559242, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=230, Percent_Identity=29.5652173913043, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI22024126, Length=212, Percent_Identity=29.2452830188679, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668781, Length=188, Percent_Identity=34.5744680851064, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356513, Length=188, Percent_Identity=34.5744680851064, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 55395; Mature: 55263

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEKSGGFRSRTPKAQQEPAKQKPQARKSPSKKAPARGQGQSQGQRQGQSSGKGGGNRK
CCCCCCCCCCCCCCCHHHCCHHCCCHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
PPAQAREVRALGVDKPREIAFEVLDRVRTGEAYANLVLPRLLSKHNLSGRDAAFATEITY
CCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHH
GTLRNVGLLDEVIKAASGRELSDIDPEVLDVLRLGAYQVMFTRVEDHAAVDTSVKMVGGL
HHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHH
KKFQATGFANAILRNITRKEPEQWLKELEPAEELARVAFRTAHPRWIAQSFSQVLPADEL
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
EAALAADSERPVVHLVARPGEISAEELALITGGDEGKYSPYAVYLEGGDPGDIEPVKDGL
HHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHH
AAVQDEGSQLIARALVEIPVEGTDAGRWLDMCAGPGGKAALIGALARMDRATVDAVEVSD
HHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEECCH
HRARLIEKSVRGLPVKVHVGDGRTINLTGGYDRALVDAPCSGLGALRRRPEARWRKQESD
HHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCHHHHCCCHHHHHHHCCCHHHHHHCCCC
IVELNTLQYELLESAVNKVRSGGVIVYSTCSPDLRETRGIVDKALGALEIEELEAAEFMP
EEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCC
GMTDTGDEKSVQMWPHRHGTDAMFVAVLRKK
CCCCCCCCCCEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SLEKSGGFRSRTPKAQQEPAKQKPQARKSPSKKAPARGQGQSQGQRQGQSSGKGGGNRK
CCCCCCCCCCCCCCHHHCCHHCCCHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
PPAQAREVRALGVDKPREIAFEVLDRVRTGEAYANLVLPRLLSKHNLSGRDAAFATEITY
CCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHH
GTLRNVGLLDEVIKAASGRELSDIDPEVLDVLRLGAYQVMFTRVEDHAAVDTSVKMVGGL
HHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHH
KKFQATGFANAILRNITRKEPEQWLKELEPAEELARVAFRTAHPRWIAQSFSQVLPADEL
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
EAALAADSERPVVHLVARPGEISAEELALITGGDEGKYSPYAVYLEGGDPGDIEPVKDGL
HHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHH
AAVQDEGSQLIARALVEIPVEGTDAGRWLDMCAGPGGKAALIGALARMDRATVDAVEVSD
HHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEECCH
HRARLIEKSVRGLPVKVHVGDGRTINLTGGYDRALVDAPCSGLGALRRRPEARWRKQESD
HHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCHHHHCCCHHHHHHHCCCHHHHHHCCCC
IVELNTLQYELLESAVNKVRSGGVIVYSTCSPDLRETRGIVDKALGALEIEELEAAEFMP
EEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCC
GMTDTGDEKSVQMWPHRHGTDAMFVAVLRKK
CCCCCCCCCCEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]