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The map label for this gene is ribC [H]

Identifier: 62390478

GI number: 62390478

Start: 1693104

End: 1693739

Strand: Reverse

Name: ribC [H]

Synonym: cg1799

Alternate gene names: 62390478

Gene position: 1693739-1693104 (Counterclockwise)

Preceding gene: 62390479

Following gene: 62390477

Centisome position: 51.6

GC content: 54.09

Gene sequence:

>636_bases
ATGTTCACAGGTATTGTCGAGGAGCTTGGCTCCGTTGCAGGCGTGGAACATCTGGGAGATTCCATCCGGATGCAGATTTC
CGCGTCCACCGTTTTAGAGGGTGTGCATTTGGGGGATTCCATTTCTGTCAATGGTGTGTGCTTGACAGTGGCGTCCTTTG
GCGAGGGACATTTCACTGCAGACCTCATGCAGGAAACCTTAGATCGCAGCTCCCTGGGCGCATTATCCACCGGTAGCAAA
GTCAACCTTGAGCGCGCCATGGCAGCCGATGGCCGTCTGGGTGGACACATCATGCAAGGCCATGTTGATGCCACCACCTC
GCTGATCAAGCGCACCAGCTCAGAGAACTGGGATGTTCTGCGTTTTGAGCTGCCAGCTGATTTGGCTCGCTATGTGGTGG
AAAAAGGCTCCATCGCACTCAATGGCACATCCTTGACTGTATCGTCTTTGGGTGATGATTGGTTTGAGGTTTCCCTGATT
CCCACCACCTTGCGCGACACCACCCACGGCGAACTGGCGGTAGGGGATATCGTAAACATTGAGGTTGATGTGATCGCTAA
GTACGTCGAACGCATGATGACGCGCGGCGTGGCTGGAAACACTCCCAATGACTACACCGATTTCACGAGAGACTAG

Upstream 100 bases:

>100_bases
ACAAGAAACCACGATGGATCAGATTATGCGTTTTGACACCACGTCCGTGAGACAGTTGGGTTCAGATGTATTGATAGAAA
TGATGAGAAAGGAACACTAA

Downstream 100 bases:

>100_bases
GTTAGACAACGTGAGTGAACATGAGCAGGCACACAGCCAATTAGATTCTGTTGAAGAGGCCATCGCTGACATCGCTGCGG
GTAAAGCCGTCGTGGTGGTA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFTGIVEELGSVAGVEHLGDSIRMQISASTVLEGVHLGDSISVNGVCLTVASFGEGHFTADLMQETLDRSSLGALSTGSK
VNLERAMAADGRLGGHIMQGHVDATTSLIKRTSSENWDVLRFELPADLARYVVEKGSIALNGTSLTVSSLGDDWFEVSLI
PTTLRDTTHGELAVGDIVNIEVDVIAKYVERMMTRGVAGNTPNDYTDFTRD

Sequences:

>Translated_211_residues
MFTGIVEELGSVAGVEHLGDSIRMQISASTVLEGVHLGDSISVNGVCLTVASFGEGHFTADLMQETLDRSSLGALSTGSK
VNLERAMAADGRLGGHIMQGHVDATTSLIKRTSSENWDVLRFELPADLARYVVEKGSIALNGTSLTVSSLGDDWFEVSLI
PTTLRDTTHGELAVGDIVNIEVDVIAKYVERMMTRGVAGNTPNDYTDFTRD
>Mature_211_residues
MFTGIVEELGSVAGVEHLGDSIRMQISASTVLEGVHLGDSISVNGVCLTVASFGEGHFTADLMQETLDRSSLGALSTGSK
VNLERAMAADGRLGGHIMQGHVDATTSLIKRTSSENWDVLRFELPADLARYVVEKGSIALNGTSLTVSSLGDDWFEVSLI
PTTLRDTTHGELAVGDIVNIEVDVIAKYVERMMTRGVAGNTPNDYTDFTRD

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=210, Percent_Identity=37.1428571428571, Blast_Score=119, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319733, Length=205, Percent_Identity=38.5365853658537, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22562; Mature: 22562

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEELGSVAGVEHLGDSIRMQISASTVLEGVHLGDSISVNGVCLTVASFGEGHFTA
CCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCEEECEEEEEEEECCCCCCHH
DLMQETLDRSSLGALSTGSKVNLERAMAADGRLGGHIMQGHVDATTSLIKRTSSENWDVL
HHHHHHHCHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHCCCCCCEEE
RFELPADLARYVVEKGSIALNGTSLTVSSLGDDWFEVSLIPTTLRDTTHGELAVGDIVNI
EEECCHHHHHHHHHCCCEEECCCEEEEECCCCCEEEEEEECCCCCCCCCCCEEECCEEEE
EVDVIAKYVERMMTRGVAGNTPNDYTDFTRD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFTGIVEELGSVAGVEHLGDSIRMQISASTVLEGVHLGDSISVNGVCLTVASFGEGHFTA
CCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCEEECEEEEEEEECCCCCCHH
DLMQETLDRSSLGALSTGSKVNLERAMAADGRLGGHIMQGHVDATTSLIKRTSSENWDVL
HHHHHHHCHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHCCCCCCEEE
RFELPADLARYVVEKGSIALNGTSLTVSSLGDDWFEVSLIPTTLRDTTHGELAVGDIVNI
EEECCHHHHHHHHHCCCEEECCCEEEEECCCCCEEEEEEECCCCCCCCCCCEEECCEEEE
EVDVIAKYVERMMTRGVAGNTPNDYTDFTRD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]