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The map label for this gene is gap

Identifier: 62390470

GI number: 62390470

Start: 1684089

End: 1685093

Strand: Reverse

Name: gap

Synonym: cg1791

Alternate gene names: 62390470

Gene position: 1685093-1684089 (Counterclockwise)

Preceding gene: 62390471

Following gene: 62390469

Centisome position: 51.33

GC content: 56.82

Gene sequence:

>1005_bases
ATGACCATTCGTGTTGGTATTAACGGATTTGGCCGTATCGGACGTAACTTCTTCCGCGCAGTTCTGGAGCGCAGCGACGA
TCTCGAGGTAGTTGCAGTCAACGACCTCACCGACAACAAGACCCTTTCCACCCTTCTCAAGTTCGACTCCATCATGGGCC
GCCTTGGCCAGGAAGTTGAATACGACGATGACTCCATCACCGTTGGTGGCAAGCGCATCGCTGTTTACGCAGAGCGCGAT
CCAAAGAACCTGGACTGGGCTGCACACAACGTTGACATCGTGATCGAGTCCACCGGCTTCTTCACCGATGCAAACGCGGC
TAAGGCTCACATCGAAGCAGGTGCCAAGAAGGTCATCATCTCCGCACCAGCAAGCAACGAAGACGCAACCTTCGTTTACG
GTGTGAACCACGAGTCCTACGATCCTGAGAACCACAACGTGATCTCCGGCGCATCTTGCACCACCAACTGCCTCGCACCA
ATGGCAAAGGTCCTAAACGACAAGTTCGGCATCGAGAACGGCCTCATGACCACCGTTCACGCATACACTGGCGACCAGCG
CCTGCACGATGCACCTCACCGCGACCTGCGTCGTGCACGTGCAGCAGCAGTCAACATCGTTCCTACCTCCACCGGTGCAG
CTAAGGCTGTTGCTCTGGTTCTCCCAGAGCTCAAGGGCAAGCTTGACGGCTACGCACTTCGCGTTCCAGTTATCACCGGT
TCCGCAACCGACCTGACCTTCAACACCAAGTCTGAGGTCACCGTTGAGTCCATCAACGCTGCAATCAAGGAAGCTGCAGT
CGGCGAGTTCGGCGAGACCCTGGCTTACTCCGAAGAGCCACTGGTTTCCACCGACATCGTCCACGATTCCCACGGCTCCA
TCTTCGACGCTGGCCTGACCAAGGTCTCCGGCAACACCGTCAAGGTTGTTTCCTGGTACGACAACGAGTGGGGCTACACC
TGCCAGCTCCTGCGTCTGACCGAGCTCGTAGCTTCCAAGCTCTAA

Upstream 100 bases:

>100_bases
TTGGGTTCTGTCAGCTCAAGAATTCTTGAGTGACCGATGCTCTGATTGACCTAACTGCTTGACACATTGCATTTCCTACA
ATCTTTAGAGGAGACACAAC

Downstream 100 bases:

>100_bases
TTAGTTCACATCGCTAACGTGGGCGATCGATGCTCACGGTGATGTGTCATCCCAATAGCCCGGGGTGTGCCTCGGCGCAC
CCCGGGCTATTTTGTGTCTT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVEYDDDSITVGGKRIAVYAERD
PKNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVIISAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAP
MAKVLNDKFGIENGLMTTVHAYTGDQRLHDAPHRDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITG
SATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLTKVSGNTVKVVSWYDNEWGYT
CQLLRLTELVASKL

Sequences:

>Translated_334_residues
MTIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVEYDDDSITVGGKRIAVYAERD
PKNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVIISAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAP
MAKVLNDKFGIENGLMTTVHAYTGDQRLHDAPHRDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITG
SATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLTKVSGNTVKVVSWYDNEWGYT
CQLLRLTELVASKL
>Mature_333_residues
TIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVEYDDDSITVGGKRIAVYAERDP
KNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVIISAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAPM
AKVLNDKFGIENGLMTTVHAYTGDQRLHDAPHRDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITGS
ATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLTKVSGNTVKVVSWYDNEWGYTC
QLLRLTELVASKL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=47.0059880239521, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=44.9101796407186, Blast_Score=278, Evalue=4e-75,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=51.8292682926829, Blast_Score=317, Evalue=7e-88,
Organism=Escherichia coli, GI1789295, Length=336, Percent_Identity=43.452380952381, Blast_Score=280, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=49.5548961424332, Blast_Score=300, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=49.5548961424332, Blast_Score=299, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=50.1483679525223, Blast_Score=299, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=50.1483679525223, Blast_Score=299, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=50.9036144578313, Blast_Score=330, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=52.4096385542169, Blast_Score=329, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=51.5060240963855, Blast_Score=325, Evalue=7e-90,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=47.3053892215569, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=47.3053892215569, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=47.3053892215569, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=47.3053892215569, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=47.0769230769231, Blast_Score=283, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G3P_CORGL (Q01651)

Other databases:

- EMBL:   X59403
- EMBL:   BA000036
- EMBL:   BX927152
- PIR:   A43260
- RefSeq:   NP_600802.1
- RefSeq:   YP_225872.1
- ProteinModelPortal:   Q01651
- SMR:   Q01651
- World-2DPAGE:   0001:Q01651
- PRIDE:   Q01651
- GeneID:   1019556
- GeneID:   3343497
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg1791
- KEGG:   cgl:NCgl1526
- HOGENOM:   HBG571736
- OMA:   RNYFRAA
- PhylomeDB:   Q01651
- ProtClustDB:   CLSK633479
- BioCyc:   CGLU196627:CG1791-MONOMER
- BRENDA:   1.2.1.12
- GO:   GO:0005737
- GO:   GO:0006096
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR10836
- PIRSF:   PIRSF000149
- PRINTS:   PR00078
- SMART:   SM00846
- TIGRFAMs:   TIGR01534

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N

EC number: =1.2.1.12

Molecular weight: Translated: 36046; Mature: 35915

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00071 GAPDH

Important sites: ACT_SITE 153-153 BINDING 35-35 BINDING 79-79 BINDING 183-183 BINDING 198-198 BINDING 234-234 BINDING 315-315

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVE
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
YDDDSITVGGKRIAVYAERDPKNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVII
CCCCEEEECCEEEEEEECCCCCCCCEEECCEEEEEECCCCEECCCHHHHHHHCCCEEEEE
SAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAPMAKVLNDKFGIENGLMTTVH
ECCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AYTGDQRLHDAPHRDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITG
EECCCCHHCCCCHHHHHHHHHHEEEEEECCCCHHHHHHEEEHHHCCCCCCEEEEEEEEEC
SATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLT
CCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCE
KVSGNTVKVVSWYDNEWGYTCQLLRLTELVASKL
EECCCEEEEEEEECCCCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure 
TIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVE
EEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
YDDDSITVGGKRIAVYAERDPKNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVII
CCCCEEEECCEEEEEEECCCCCCCCEEECCEEEEEECCCCEECCCHHHHHHHCCCEEEEE
SAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAPMAKVLNDKFGIENGLMTTVH
ECCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AYTGDQRLHDAPHRDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITG
EECCCCHHCCCCHHHHHHHHHHEEEEEECCCCHHHHHHEEEHHHCCCCCCEEEEEEEEEC
SATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLT
CCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCE
KVSGNTVKVVSWYDNEWGYTCQLLRLTELVASKL
EECCCEEEEEEEECCCCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400158; 12948626