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The map label for this gene is pgk [H]

Identifier: 62390469

GI number: 62390469

Start: 1682655

End: 1683872

Strand: Reverse

Name: pgk [H]

Synonym: cg1790

Alternate gene names: 62390469

Gene position: 1683872-1682655 (Counterclockwise)

Preceding gene: 62390470

Following gene: 62390468

Centisome position: 51.3

GC content: 57.8

Gene sequence:

>1218_bases
ATGGCTGTTAAGACCCTCAAGGACTTGCTCGACGAAGGCGTAGACGGACGCCACGTCATCGTTCGATCTGACTTCAATGT
TCCCCTCAACGATGACCGCGAGATCACCGATAAGGGCCGAATCATTGCCTCCCTACCAACCCTTAAAGCACTGAGCGAAG
GTGGCGCAAAGGTCATCGTCATGGCTCACCTTGGCCGCCCAAAGGGCGAGGTCAACGAGAAGTACTCCCTCGCACCTGTC
GCTGAGGCACTCTCCGATGAGCTTGGCCAGTACGTTGCACTTGCCGCAGACGTTGTTGGCGAAGACGCACACGAGCGCGC
AAACGGCCTGACCGAGGGCGACATCCTGCTCCTGGAGAACGTGCGCTTCGACCCACGCGAAACCTCCAAGGACGAGGCAG
AGCGCACCGCTTTCGCTCAGGAGCTCGCAGCTCTTGCAGCAGACAACGGCGCATTCGTTTCTGACGGCTTCGGTGTTGTC
CACCGCGCACAGACCTCCGTCTACGACATTGCAAAGTTGCTGCCACACTACGCTGGCGGACTGGTAGAGACCGAGATTTC
CGTTCTGGAAAAGATCGCAGAATCACCAGAGGCACCATACGTAGTGGTTCTCGGTGGATCCAAGGTCTCTGACAAGATCG
GTGTTATTGAGGCGCTGGCTGCCAAGGCTGACAAGATCATCGTCGGTGGCGGCATGTGCTACACCTTCCTCGCAGCTCAG
GGACACAACGTTCAGCAGTCCCTCCTGCAGGAAGAAATGAAGGCTACCTGCACCGACCTGCTCGCACGCTTCGGTGACAA
GATCGTTCTCCCAGTTGACCTGGTTGCAGCATCCGAATTTAACAAGGACGCAGAGAAGCAGATCGTTGACCTGGACTCCA
TCCCAGAAGGCTGGATGTCTCTTGACATCGGACCAGAGTCCGTCAAGAACTTCGGTGAGGTTCTCAGCACCGCTAAGACC
ATCTTCTGGAACGGCCCAATGGGCGTGTTCGAGTTCGCAGCATTCTCTGAAGGCACCCGCGGCATCGCCCAGGCCATCAT
CGATGCAACTGCAGGCAACGACGCATTCTCCGTTGTTGGCGGTGGCGACTCCGCAGCATCCGTTCGCGTGCTCGGCCTGA
ACGAAGACGGCTTCTCCCACATCTCCACCGGTGGTGGCGCATCCCTCGAGTACCTTGAAGGCAAGGAACTCCCAGGCGTT
GCAATTCTCGCTCAGTAA

Upstream 100 bases:

>100_bases
ATACCGGTGCCAGCGCCACACAATGTGTGGCAATCTGGGACAGTGCATCACATTGCACCAGAAGAATTTTTTAAACAATC
AAATCTCCAAGGAGTACGGC

Downstream 100 bases:

>100_bases
ATCCGACACGGCCCTTTGTTAGAAAACAAAACATAAAGGGCCACCGGGAAACTTTTTTAAGAAAGGTGTGTTTCACACAT
GGCACGTAAGCCACTTATCG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIVMAHLGRPKGEVNEKYSLAPV
AEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLENVRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVV
HRAQTSVYDIAKLLPHYAGGLVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQ
GHNVQQSLLQEEMKATCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMSLDIGPESVKNFGEVLSTAKT
IFWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVGGGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGV
AILAQ

Sequences:

>Translated_405_residues
MAVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIVMAHLGRPKGEVNEKYSLAPV
AEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLENVRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVV
HRAQTSVYDIAKLLPHYAGGLVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQ
GHNVQQSLLQEEMKATCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMSLDIGPESVKNFGEVLSTAKT
IFWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVGGGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGV
AILAQ
>Mature_404_residues
AVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIVMAHLGRPKGEVNEKYSLAPVA
EALSDELGQYVALAADVVGEDAHERANGLTEGDILLLENVRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVVH
RAQTSVYDIAKLLPHYAGGLVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQG
HNVQQSLLQEEMKATCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMSLDIGPESVKNFGEVLSTAKTI
FWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVGGGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGVA
ILAQ

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=414, Percent_Identity=41.304347826087, Blast_Score=288, Evalue=5e-78,
Organism=Homo sapiens, GI31543397, Length=414, Percent_Identity=41.304347826087, Blast_Score=283, Evalue=3e-76,
Organism=Escherichia coli, GI1789294, Length=408, Percent_Identity=41.9117647058824, Blast_Score=278, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI17508823, Length=406, Percent_Identity=41.6256157635468, Blast_Score=283, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6319857, Length=426, Percent_Identity=40.1408450704225, Blast_Score=286, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24581203, Length=419, Percent_Identity=39.3794749403341, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17136394, Length=405, Percent_Identity=39.7530864197531, Blast_Score=256, Evalue=2e-68,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42698; Mature: 42566

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIV
CCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEE
MAHLGRPKGEVNEKYSLAPVAEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLEN
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEC
VRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVVHRAQTSVYDIAKLLPHYAGG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCC
LVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQ
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHC
GHNVQQSLLQEEMKATCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMS
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHCCCCHHHHHHCCCCCCCCCEE
LDIGPESVKNFGEVLSTAKTIFWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVG
ECCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEE
GGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGVAILAQ
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEC
>Mature Secondary Structure 
AVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIV
CHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEE
MAHLGRPKGEVNEKYSLAPVAEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLEN
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEC
VRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVVHRAQTSVYDIAKLLPHYAGG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCC
LVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQ
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHC
GHNVQQSLLQEEMKATCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMS
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHCCCCHHHHHHCCCCCCCCCEE
LDIGPESVKNFGEVLSTAKTIFWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVG
ECCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEE
GGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGVAILAQ
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA