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The map label for this gene is nifS1 [H]

Identifier: 62390119

GI number: 62390119

Start: 1298680

End: 1299810

Strand: Direct

Name: nifS1 [H]

Synonym: cg1388

Alternate gene names: 62390119

Gene position: 1298680-1299810 (Clockwise)

Preceding gene: 62390118

Following gene: 62390123

Centisome position: 39.56

GC content: 59.59

Gene sequence:

>1131_bases
TTGAACACTTTTTATCTGGACCATGCAGCCACCACACCAATGCGTGAGGTGGCCGCAGCTGCGTGGATGGAAAACGCGCA
GGCATTGAATCCCGCGAGTCAGTACGGTTCGGGGCGTAAGGCGCGCAGCGTTGCGGATTCGGCTCGTGAAGAAATTGCTT
CTTTGCTGGGCTGTGAACCTATCGAGGTTGTGTTTACCGCGTCCGGCACGGAGGCAGATAACCTCGCTGTGCAGGGGTTA
TTCCACGCATCGCCTCTCAATCGGATTATTTCTACGCCGATCGAGCACCCCGGGATTCTGGAAACCGTCAAGGCTCTAGA
ACTTGGCGGGGCAGAGGCGGAGCTCATGCCGATCGGTCCAGATGGACGAGTGTCTTCCTTCGAAGCGCTGGACAAGCCTG
CCGCGGTTGCCACTATGATGTGGGCGAACAATGAGACCGGCGCGATTCAGCCGGTTTCTGAGTTCATCGCCGCCGCGCAG
GCGTCCGGCACGCCAACACACATCGATGCGGTTCAGGTCGTTGGCCATCTGCCGGTCAATTTTGATGAGCTCGGCGCCAC
CACTTTGGCTGCCTCCGCGCACAAATTCGGTGGACCACGTGGCGTCGGCCTGCTGTTGGTGAGGCGCTCACCAGCACCTT
CAGCCGTATTGCACGGAGGTGGTCAGGAGCGCGGCATCCGTCCAGGCACCCTTGATGTCGCCGGCGCAGCTGCCACCGCA
GCCGCATTACGCGAAGCAGTGGCCGAGCTTGACGGCGAAGCCACCCGCCTGCGCGGACTTAAAAAGATGCTTCTCGACGC
CATCCTCCACACCATCCCCAACGTACTGGTCCACACCACCGAACCATCCCTGCCAGGACACCTGCATCTCTCCTTCCCAG
GAGCAGAAGGCGATAGTTTGATCATGCTGCTCGACTCCTTGCGGATCGAAGCCTCCACAGGTTCGGCCTGCTCCAACGGT
GTAAACCGTGCCAGCCACGTCCTTTTGGCCATGGGAATTTCCGAAACCGACGCCCGTGGTGCCATCCGATTCACCCTCGG
AAGAACCACCACTGAAGAATCCATCAAGGCAGTGATCGCCGTGATCGAAGACGTAGTGACCAGGGCTCGTACTGCGGGAA
TGGCTTTTTAG

Upstream 100 bases:

>100_bases
ACGCGCCGATCTTCCAGATTGCGGACCTCGGTGTCGTTGGCGACCTCTTTGACATCGCCCCTGCGCTCATCGAAGAGATC
AACAAGCGCAAGTAGGAGTT

Downstream 100 bases:

>100_bases
CGACCGTAAATCGCATAGTGCAGTTCCGTTGCCAGCGGGCAGATCACCTGCTGGTGCGACAGCGGAACATTTTGGCAGTC
GCCAACAACGGGAGATCCTG

Product: pyridoxal-phosphate-dependent aminotransferase/cysteine desulfinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNTFYLDHAATTPMREVAAAAWMENAQALNPASQYGSGRKARSVADSAREEIASLLGCEPIEVVFTASGTEADNLAVQGL
FHASPLNRIISTPIEHPGILETVKALELGGAEAELMPIGPDGRVSSFEALDKPAAVATMMWANNETGAIQPVSEFIAAAQ
ASGTPTHIDAVQVVGHLPVNFDELGATTLAASAHKFGGPRGVGLLLVRRSPAPSAVLHGGGQERGIRPGTLDVAGAAATA
AALREAVAELDGEATRLRGLKKMLLDAILHTIPNVLVHTTEPSLPGHLHLSFPGAEGDSLIMLLDSLRIEASTGSACSNG
VNRASHVLLAMGISETDARGAIRFTLGRTTTEESIKAVIAVIEDVVTRARTAGMAF

Sequences:

>Translated_376_residues
MNTFYLDHAATTPMREVAAAAWMENAQALNPASQYGSGRKARSVADSAREEIASLLGCEPIEVVFTASGTEADNLAVQGL
FHASPLNRIISTPIEHPGILETVKALELGGAEAELMPIGPDGRVSSFEALDKPAAVATMMWANNETGAIQPVSEFIAAAQ
ASGTPTHIDAVQVVGHLPVNFDELGATTLAASAHKFGGPRGVGLLLVRRSPAPSAVLHGGGQERGIRPGTLDVAGAAATA
AALREAVAELDGEATRLRGLKKMLLDAILHTIPNVLVHTTEPSLPGHLHLSFPGAEGDSLIMLLDSLRIEASTGSACSNG
VNRASHVLLAMGISETDARGAIRFTLGRTTTEESIKAVIAVIEDVVTRARTAGMAF
>Mature_376_residues
MNTFYLDHAATTPMREVAAAAWMENAQALNPASQYGSGRKARSVADSAREEIASLLGCEPIEVVFTASGTEADNLAVQGL
FHASPLNRIISTPIEHPGILETVKALELGGAEAELMPIGPDGRVSSFEALDKPAAVATMMWANNETGAIQPVSEFIAAAQ
ASGTPTHIDAVQVVGHLPVNFDELGATTLAASAHKFGGPRGVGLLLVRRSPAPSAVLHGGGQERGIRPGTLDVAGAAATA
AALREAVAELDGEATRLRGLKKMLLDAILHTIPNVLVHTTEPSLPGHLHLSFPGAEGDSLIMLLDSLRIEASTGSACSNG
VNRASHVLLAMGISETDARGAIRFTLGRTTTEESIKAVIAVIEDVVTRARTAGMAF

Specific function: Catalyzes the removal of elemental sulfur from cysteine to produce alanine [H]

COG id: COG1104

COG function: function code E; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=382, Percent_Identity=32.1989528795811, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI156713448, Length=410, Percent_Identity=29.7560975609756, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI48994898, Length=379, Percent_Identity=37.2031662269129, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1787970, Length=156, Percent_Identity=29.4871794871795, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25143064, Length=380, Percent_Identity=33.9473684210526, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17533177, Length=319, Percent_Identity=32.6018808777429, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319831, Length=376, Percent_Identity=32.1808510638298, Blast_Score=190, Evalue=3e-49,
Organism=Drosophila melanogaster, GI20129463, Length=364, Percent_Identity=34.6153846153846, Blast_Score=199, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010240
- InterPro:   IPR017772
- InterPro:   IPR016454
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 39031; Mature: 39031

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFYLDHAATTPMREVAAAAWMENAQALNPASQYGSGRKARSVADSAREEIASLLGCEP
CCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
IEVVFTASGTEADNLAVQGLFHASPLNRIISTPIEHPGILETVKALELGGAEAELMPIGP
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
DGRVSSFEALDKPAAVATMMWANNETGAIQPVSEFIAAAQASGTPTHIDAVQVVGHLPVN
CCCCCHHHHHCCCHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
FDELGATTLAASAHKFGGPRGVGLLLVRRSPAPSAVLHGGGQERGIRPGTLDVAGAAATA
HHHHCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHEECCCCCCCCCCCCCCHHHHHHHH
AALREAVAELDGEATRLRGLKKMLLDAILHTIPNVLVHTTEPSLPGHLHLSFPGAEGDSL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCEEEEECCCCCCCEE
IMLLDSLRIEASTGSACSNGVNRASHVLLAMGISETDARGAIRFTLGRTTTEESIKAVIA
EEEEEHHEEECCCCCHHHHHHHHHHHEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHH
VIEDVVTRARTAGMAF
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTFYLDHAATTPMREVAAAAWMENAQALNPASQYGSGRKARSVADSAREEIASLLGCEP
CCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
IEVVFTASGTEADNLAVQGLFHASPLNRIISTPIEHPGILETVKALELGGAEAELMPIGP
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
DGRVSSFEALDKPAAVATMMWANNETGAIQPVSEFIAAAQASGTPTHIDAVQVVGHLPVN
CCCCCHHHHHCCCHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
FDELGATTLAASAHKFGGPRGVGLLLVRRSPAPSAVLHGGGQERGIRPGTLDVAGAAATA
HHHHCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHEECCCCCCCCCCCCCCHHHHHHHH
AALREAVAELDGEATRLRGLKKMLLDAILHTIPNVLVHTTEPSLPGHLHLSFPGAEGDSL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCEEEEECCCCCCCEE
IMLLDSLRIEASTGSACSNGVNRASHVLLAMGISETDARGAIRFTLGRTTTEESIKAVIA
EEEEEHHEEECCCCCHHHHHHHHHHHEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHH
VIEDVVTRARTAGMAF
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA