Click here to switch to the map view.

The map label for this gene is fixB [H]

Identifier: 62390118

GI number: 62390118

Start: 1297721

End: 1298674

Strand: Direct

Name: fixB [H]

Synonym: cg1387

Alternate gene names: 62390118

Gene position: 1297721-1298674 (Clockwise)

Preceding gene: 62390117

Following gene: 62390119

Centisome position: 39.53

GC content: 57.34

Gene sequence:

>954_bases
ATGTCTATTTCTTATGTGCTGGTTGAGCAGCTAGATGGCCGCCCAGAACCAGTTACCCTTGAATTGATCACTGCTGCTCG
CGCACTCGGTGACGTCGTTGCCGTTGTCGTTGGCGAGCCAGGTGCCGGCGTAAACCTTGCTGCTGAGCTCGGCAATTGGG
GTGCAGCACAGGTTGTTTCCGCTGAAATCTCTGGCGCTTCCAACCGTTTGATCTTGCCTGCTGTTGATGCGCTGCACATT
TTGGCTGCGAACAACCCAGGTCCAATTGTTATCGCTGCAACTGCAAGCGGTAATGAGATCGCTGGTCGTTTGGCTGCCCG
TTTGGCTTCTGGTGTGCTCACCGATGTCGTCGGAATCAATGCCGACCGCACCGCACAGCAGTCCATTTTCGGCGACACCA
TTCAGGTGTCCGCTGCAGTTGGTGGCGCTTCACCGCTGTACACCCTGCGTCCAGGTGCCCTTGATGGCGTGGCCGTTCCT
GCAACCGGTGAATTGGCAACCATTGAGATCCCAGGCGCAACCGCCAAGGATGTCACCATCACCTCCTTCACGCCAAGCAC
CCAGAGCGATCGCCCTGAGCTGCCACAGGCAAAGGTCGTTATCGCAGGTGGACGTGGTGTCGGAAGCGAAGAAAACTTCC
GCAGCATCGTTGAACCACTGGCAGATGCATTGGGCGGTGCCGTTGGCGCAACCCGCGACGCCGTTGATCTGGGCTACTAC
CCAGGCGAGTACCAGGTTGGTCAGACCGGTGTCACCGTGTCCCCAGACCTCTACATCGGCCTCGGCATTTCCGGTGCAAT
TCAGCACACTTCTGGTATGCAGACCGCAAAGAAGGTTATTGTGATCAACAACGATGAGGACGCGCCGATCTTCCAGATTG
CGGACCTCGGTGTCGTTGGCGACCTCTTTGACATCGCCCCTGCGCTCATCGAAGAGATCAACAAGCGCAAGTAG

Upstream 100 bases:

>100_bases
GTGATGTCATTGGTGCATCGGGTGCTGCTGAAAAGATTGCTGAGTACCTCGCTTCAGAGAACCTCATCTAGCCACTATCT
TCACAAAGGAGAACATTTAA

Downstream 100 bases:

>100_bases
GAGTTTTGAACACTTTTTATCTGGACCATGCAGCCACCACACCAATGCGTGAGGTGGCCGCAGCTGCGTGGATGGAAAAC
GCGCAGGCATTGAATCCCGC

Product: electron transfer flavoprotein, alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVSAEISGASNRLILPAVDALHI
LAANNPGPIVIAATASGNEIAGRLAARLASGVLTDVVGINADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVP
ATGELATIEIPGATAKDVTITSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYY
PGEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVGDLFDIAPALIEEINKRK

Sequences:

>Translated_317_residues
MSISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVSAEISGASNRLILPAVDALHI
LAANNPGPIVIAATASGNEIAGRLAARLASGVLTDVVGINADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVP
ATGELATIEIPGATAKDVTITSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYY
PGEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVGDLFDIAPALIEEINKRK
>Mature_316_residues
SISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVSAEISGASNRLILPAVDALHIL
AANNPGPIVIAATASGNEIAGRLAARLASGVLTDVVGINADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVPA
TGELATIEIPGATAKDVTITSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYYP
GEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVGDLFDIAPALIEEINKRK

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=319, Percent_Identity=37.3040752351097, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI189181759, Length=234, Percent_Identity=40.5982905982906, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1787990, Length=240, Percent_Identity=28.3333333333333, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786226, Length=229, Percent_Identity=32.7510917030568, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082157, Length=221, Percent_Identity=28.0542986425339, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=320, Percent_Identity=38.125, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6325261, Length=244, Percent_Identity=35.655737704918, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=36.1022364217252, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=36.1022364217252, Blast_Score=165, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32144; Mature: 32013

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVS
CCEEEEEHHHHCCCCCCEEEHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCEEEE
AEISGASNRLILPAVDALHILAANNPGPIVIAATASGNEIAGRLAARLASGVLTDVVGIN
EECCCCCCEEEEEECCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
ADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVPATGELATIEIPGATAKDVTI
CCCHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCCEEECCCCCEEEEEECCCCCCCEEE
TSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYY
EEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCC
PGEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVG
CCCEEECCCCEEECCCEEEEECCCCHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCHHH
DLFDIAPALIEEINKRK
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVS
CEEEEEHHHHCCCCCCEEEHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCEEEE
AEISGASNRLILPAVDALHILAANNPGPIVIAATASGNEIAGRLAARLASGVLTDVVGIN
EECCCCCCEEEEEECCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
ADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVPATGELATIEIPGATAKDVTI
CCCHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCCEEECCCCCEEEEEECCCCCCCEEE
TSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYY
EEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCC
PGEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVG
CCCEEECCCCEEECCCEEEEECCCCHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCHHH
DLFDIAPALIEEINKRK
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]