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The map label for this gene is rho [H]

Identifier: 62390087

GI number: 62390087

Start: 1266610

End: 1268898

Strand: Direct

Name: rho [H]

Synonym: cg1354

Alternate gene names: 62390087

Gene position: 1266610-1268898 (Clockwise)

Preceding gene: 62390079

Following gene: 62390088

Centisome position: 38.58

GC content: 55.7

Gene sequence:

>2289_bases
GTGACAACCACAGACAACACCGCAGCGAATCAGGGTGAACTGACCGCCCTCCGACTGCCGGATCTGCGCAAAATTGCCGC
CGACCTTGGGCTCAAGGGAACCTCGGCATTGCGTAAGGGCGATCTGATCAACGCCATCTCTGCAGCCCGCGAGGGTAAGC
CAACCGCAGCTGCGAAGAAGACTTCCCCACGCAAGGCCCCATCACGCACCCGTGCGACACAGCCTTCCGCACCGGTTGAG
CAAGCACAAGAAGCTCCCGCGCAAACTTCAACTGCACCTGCTTCAGCACCATCTGAAGAGACTCCCGCAGCTCCCGCTCG
TCGTGGACGTCGCCGTGTAACCACCACCGCGACCACCCCAGAGCCAGCAGCGCCTGCACAATCCCAGCCTGCAGAAGCTC
AACCAGCACAGACTCAGGCTGCACAGCAAGAAGAACTTCCTGTTGCAGCGAAGGAGTCCGCACCAGCTACAGAAAACACT
CAGGGCCAAGCTCAGGGCCAAGCTCAGGGCCAAGCTCAGGGCGATGAGCACGATGATCGTTTTGAGTCCCGTTCTGCTGC
ACGCCGAGCACGCCGCAACCGTCAGCGCCAGATCCACCGCGATGGCGATGACAATGCGAATGCAAACACAGAGTCTGAGC
AGAACACCCCTGCCCAGAACGCAACCGCACAGGCTGAGTCTGAGCAGACTGCAGCTCCTGCACAGGCTGAAGCAGCTGAG
CAGAACCAGAACGATAACAGCGAGTCCTCCGAGAACCGCAGCGATAACTACCGCAACAACAATCGTCGTTCCCGCAACAA
CCGGAACAATCGCAATTACCGCGATAACAACGAGTCCTCTGATAATGCAGGACAGTCCAGCAATGATGATGCCGACAACA
ATCAGGCACGGTCTGAGGACAATAACGACGATCGCCGTTCTCGTAATAACCGTAACAACGACCGCAATGATCGTAACGAT
CGCAATGACCGCGACAACGACGACAACGATGATCGCCGCAACCGTCGCGGACGCCGCAATCGCCGTGGACGCAACGACCG
TAACGATCGCGACAACCGAGATAACCGGGATAACCGCGACAACAGCAACGATGGCGACAACAACCAGCAAGATGAGCTGC
AGCAGGTAGCAGGCATCCTGGACATCGTGGACCATAACGTCGCATTCGTGCGCACCACCGGTTACCACGCTGCACCTTCT
GACGTGTTTGTCAGCAACCAGCTGATCCGCCGTATGGGTCTTCGTTCCGGTGACGCCATTGAAGGTCAGGTTCGTATGAA
CCAGGGTGGTGGCAACCACAACAACCATGGTCGCAACCGTCAGAAGTACAACAACTTGGTGCGCGTGGAGATGGTTAACG
GTCTTCCTGCTGAAGAGACTCGCAACCGTCCTGAGTTCGGCAAGCTGACTCCTCTGTACCCGAACCAGCGTCTGCGTTTG
GAAACTGAGCAGAAGATTCTTACCACTCGTGTGATCGACTTGATCATGCCTATTGGTAAGGGACAGCGTGCTTTGATTGT
GTCGCCACCTAAGGCTGGTAAGACCACGATCCTGCAGAACATTGCGAACGCTATTTCCACCAACAACCCAGAGTGCTACC
TCATGGTTGTTTTGGTTGATGAGCGTCCGGAAGAAGTTACTGATATGCAGCGCTCCGTCAACGGCGAAGTGATTTCTTCT
ACTTTCGATCGTCCACCATCAGAGCACACTGCGGTTGCTGAGCTGGCGATTGAGCGTGCGAAGCGCCTGGTGGAGCAGGG
CCAGGACGTCGTTGTTCTGCTTGACTCCATTACTCGTTTGGGCCGTGCGTACAACAACAGCTCACCTGCATCGGGACGTA
TTTTGTCCGGTGGTGTGGATTCCAATGCACTGTACCCGCCGAAGCGTTTCTTGGGTGCTGCTCGAAACATCGAAAATGGT
GGATCTTTGACCATCATCGCAACTGCCATGGTGGAAACCGGCTCTGCTGGTGACACCGTGATCTTCGAGGAGTTCAAGGG
CACTGGTAACGCTGAGCTGAAGCTGGATCGTAAGATCTCTGAGCGCCGCGTTTTCCCAGCTGTGGATGTTAATCCTTCTG
GTACTCGTAAGGACGAGCTGTTGCTCAACCCGGACGAGGCTCGCATTATGCACAAGCTGCGTCGTATTCTGTCTGCACTT
GATAATCAGCAAGCCATTGATCTGTTGATCAAGCAGCTGAAGAAGACCAAGTCCAATGCGGAATTCCTCATGCAGGTTGC
TTCCAGCGCTCCAATGGCAGGCACAGAAAAAGAGGAGGATTACTCCTAA

Upstream 100 bases:

>100_bases
TCAATTACACAGAAGCCGAGTTCAGCCATATTTTTCGCCCGTCATATGAAAAACGGGTACATCACCGCAGCTTGGTCTGA
ACTGCAATGAAAGGAAATCT

Downstream 100 bases:

>100_bases
TGGCATCGCAGGTTTCTGCAGTTGACGATATTTTGTCGGAGTACCACGGTCTGGAACAGCAGATGGCTGATCCGGAGTTG
CACAATGATGCGGCAGCAGC

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MTTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKKTSPRKAPSRTRATQPSAPVE
QAQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTPEPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENT
QGQAQGQAQGQAQGDEHDDRFESRSAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAE
QNQNDNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSEDNNDDRRSRNNRNNDRNDRND
RNDRDNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRDNSNDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPS
DVFVSNQLIRRMGLRSGDAIEGQVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRL
ETEQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVDERPEEVTDMQRSVNGEVISS
TFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENG
GSLTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSAL
DNQQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS

Sequences:

>Translated_762_residues
MTTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKKTSPRKAPSRTRATQPSAPVE
QAQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTPEPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENT
QGQAQGQAQGQAQGDEHDDRFESRSAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAE
QNQNDNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSEDNNDDRRSRNNRNNDRNDRND
RNDRDNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRDNSNDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPS
DVFVSNQLIRRMGLRSGDAIEGQVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRL
ETEQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVDERPEEVTDMQRSVNGEVISS
TFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENG
GSLTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSAL
DNQQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS
>Mature_761_residues
TTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKKTSPRKAPSRTRATQPSAPVEQ
AQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTPEPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENTQ
GQAQGQAQGQAQGDEHDDRFESRSAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAEQ
NQNDNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSEDNNDDRRSRNNRNNDRNDRNDR
NDRDNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRDNSNDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPSD
VFVSNQLIRRMGLRSGDAIEGQVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRLE
TEQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVDERPEEVTDMQRSVNGEVISST
FDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGG
SLTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSALD
NQQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=373, Percent_Identity=54.9597855227882, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 83968; Mature: 83837

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKK
CCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCHHHCC
TSPRKAPSRTRATQPSAPVEQAQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTP
CCCCCCCCHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCC
EPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENTQGQAQGQAQGQAQGDEHDDR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
FESRSAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
QNQNDNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSED
HCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NNDDRRSRNNRNNDRNDRNDRNDRDNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRD
CCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
NSNDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPSDVFVSNQLIRRMGLRSGDAI
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCC
EGQVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRL
CCEEEECCCCCCCCCCCCCHHHHHCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCEEE
ETEQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVD
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEC
ERPEEVTDMQRSVNGEVISSTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRL
CCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
GRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGGSLTIIATAMVETGSAGDTV
HHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCEE
IFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSAL
EEHHHCCCCCCEEEECCHHHHCCCCCEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
DNQQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTTDNTAANQGELTALRLPDLRKIAADLGLKGTSALRKGDLINAISAAREGKPTAAAKK
CCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCHHHCC
TSPRKAPSRTRATQPSAPVEQAQEAPAQTSTAPASAPSEETPAAPARRGRRRVTTTATTP
CCCCCCCCHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEECCCC
EPAAPAQSQPAEAQPAQTQAAQQEELPVAAKESAPATENTQGQAQGQAQGQAQGDEHDDR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
FESRSAARRARRNRQRQIHRDGDDNANANTESEQNTPAQNATAQAESEQTAAPAQAEAAE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
QNQNDNSESSENRSDNYRNNNRRSRNNRNNRNYRDNNESSDNAGQSSNDDADNNQARSED
HCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NNDDRRSRNNRNNDRNDRNDRNDRDNDDNDDRRNRRGRRNRRGRNDRNDRDNRDNRDNRD
CCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
NSNDGDNNQQDELQQVAGILDIVDHNVAFVRTTGYHAAPSDVFVSNQLIRRMGLRSGDAI
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCC
EGQVRMNQGGGNHNNHGRNRQKYNNLVRVEMVNGLPAEETRNRPEFGKLTPLYPNQRLRL
CCEEEECCCCCCCCCCCCCHHHHHCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCEEE
ETEQKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAISTNNPECYLMVVLVD
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEC
ERPEEVTDMQRSVNGEVISSTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRL
CCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
GRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGGSLTIIATAMVETGSAGDTV
HHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCEE
IFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLNPDEARIMHKLRRILSAL
EEHHHCCCCCCEEEECCHHHHCCCCCEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
DNQQAIDLLIKQLKKTKSNAEFLMQVASSAPMAGTEKEEDYS
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]