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The map label for this gene is glmU [H]

Identifier: 62389834

GI number: 62389834

Start: 999922

End: 1001379

Strand: Reverse

Name: glmU [H]

Synonym: cg1076

Alternate gene names: 62389834

Gene position: 1001379-999922 (Counterclockwise)

Preceding gene: 62389835

Following gene: 62389833

Centisome position: 30.5

GC content: 58.37

Gene sequence:

>1458_bases
TTGAGCGCAAGCGATTTCTCGAGCGCAGTTGTCGTTTTGGCAGCTGGTGCCGGAACCCGAATGAAATCAGACTTACAAAA
AACGTTGCATAGCATCGGTGGACGCAGTCTCATTTCACATAGCTTGCATGCAGCTGCCGGGCTTAATCCCGAGCACATTG
TTGCAGTAATTGGACATGGACGCGACCAGGTGGGTCCAGCCGTTGCCCAGGTTGCAGAAGAACTGGACCGGGAAGTCCTC
ATCGCTATCCAAGAGGAACAAAATGGCACGGGACACGCTGTGCAGTGCGCCATGGATCAGCTCGAGGGCTTTGAAGGCAC
GATCATTGTCACCAACGGCGATGTTCCCCTGCTCACCGACCACACTCTGTCTGCACTGCTGGATGCACACGTGGAAGTTC
CAACCGCTGTCACCGTGTTGACCATGCGTCTGGATGACCCCACCGGCTACGGCCGCATCGTGCGCAACGAAGAAGGCGAA
GTCACCGCCATCGTTGAGCAAAAAGATGCTTCAGCAGAAGTCCAAGCCATCGATGAGGTCAACTCCGGTGTCTTTGCTTT
CGACGCCGCCATCTTGCGTTCCGCACTGGCTGAACTGAAGTCCGACAACGCTCAGGGCGAGCTGTACCTGACCGACGTAT
TGGGCATTGCTCGTGGCGAGGGCCACCCAGTGCGCGCCCACACCGCCGCCGATGCTCGTGAACTCGCCGGTGTCAACGAT
CGTGTGCAGCTCGCAGAAGCCGGCGCCGAACTAAACCGTCGCACCGTCATCGCCGCTATGCGTGGTGGCGCAACCATCGT
TGATCCAGCAACCACCTGGATCGATGTGGAGGTTTCTATCGGCCGCGACGTGATCATCCACCCTGGCACCCAGCTCAAGG
GCGAAACTGTCATCGGAGACCGCGTTGAAGTTGGTCCAGACACCACCTTGACCAACATGACCATCGGCGACGGCGCATCC
GTAATCCGCACCCACGGTTTCGACTCCACCATCGGTGAAAACGCCACCGTTGGCCCCTTCACCTACATCCGCCCAGGAAC
CACACTGGGACCAGAAGGCAAGCTCGGTGGCTTCGTAGAAACCAAGAAGGCCACAATCGGCCGTGGCTCCAAGGTTCCAC
ACCTCACCTATGTCGGCGACGCCACCATCGGCGAGGAATCCAACATCGGAGCCTCCTCTGTCTTCGTGAACTACGACGGT
GAAAACAAGCACCACACCACCATCGGCAGCCACGTTCGCACTGGTTCTGACACCATGTTTATCGCTCCAGTGACCGTGGG
TGACGGAGCGTATTCCGGAGCCGGTACAGTAATTAAAGACGATGTTCCGCCAGGAGCCCTTGCCGTGTCCGGCGGACGCC
AACGAAACATCGAAGGCTGGGTGCAAAAGAAGCGCCCTGGAACCGCTGCAGCACAAGCCGCAGAAGCCGCCCAAAACGTC
CACAACCAGGAAGGCTAA

Upstream 100 bases:

>100_bases
TACAACTTTTCCACCCAAATAGGCAGGTTTTGGGGTTCGGGGCATTATGCTTGCTTGGGTATAAGTGCCCCGCAAGAACT
TTTAAGGATTTGAGATAATC

Downstream 100 bases:

>100_bases
GCAGGATCCTCATGACTGCTCACTGGAAACAAAACCAAAAGAACCTCATGCTGTTTTCGGGTCGTGCGCACCCAGAACTG
GCAGAAGCTGTAGCTAAAGA

Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MSASDFSSAVVVLAAGAGTRMKSDLQKTLHSIGGRSLISHSLHAAAGLNPEHIVAVIGHGRDQVGPAVAQVAEELDREVL
IAIQEEQNGTGHAVQCAMDQLEGFEGTIIVTNGDVPLLTDHTLSALLDAHVEVPTAVTVLTMRLDDPTGYGRIVRNEEGE
VTAIVEQKDASAEVQAIDEVNSGVFAFDAAILRSALAELKSDNAQGELYLTDVLGIARGEGHPVRAHTAADARELAGVND
RVQLAEAGAELNRRTVIAAMRGGATIVDPATTWIDVEVSIGRDVIIHPGTQLKGETVIGDRVEVGPDTTLTNMTIGDGAS
VIRTHGFDSTIGENATVGPFTYIRPGTTLGPEGKLGGFVETKKATIGRGSKVPHLTYVGDATIGEESNIGASSVFVNYDG
ENKHHTTIGSHVRTGSDTMFIAPVTVGDGAYSGAGTVIKDDVPPGALAVSGGRQRNIEGWVQKKRPGTAAAQAAEAAQNV
HNQEG

Sequences:

>Translated_485_residues
MSASDFSSAVVVLAAGAGTRMKSDLQKTLHSIGGRSLISHSLHAAAGLNPEHIVAVIGHGRDQVGPAVAQVAEELDREVL
IAIQEEQNGTGHAVQCAMDQLEGFEGTIIVTNGDVPLLTDHTLSALLDAHVEVPTAVTVLTMRLDDPTGYGRIVRNEEGE
VTAIVEQKDASAEVQAIDEVNSGVFAFDAAILRSALAELKSDNAQGELYLTDVLGIARGEGHPVRAHTAADARELAGVND
RVQLAEAGAELNRRTVIAAMRGGATIVDPATTWIDVEVSIGRDVIIHPGTQLKGETVIGDRVEVGPDTTLTNMTIGDGAS
VIRTHGFDSTIGENATVGPFTYIRPGTTLGPEGKLGGFVETKKATIGRGSKVPHLTYVGDATIGEESNIGASSVFVNYDG
ENKHHTTIGSHVRTGSDTMFIAPVTVGDGAYSGAGTVIKDDVPPGALAVSGGRQRNIEGWVQKKRPGTAAAQAAEAAQNV
HNQEG
>Mature_484_residues
SASDFSSAVVVLAAGAGTRMKSDLQKTLHSIGGRSLISHSLHAAAGLNPEHIVAVIGHGRDQVGPAVAQVAEELDREVLI
AIQEEQNGTGHAVQCAMDQLEGFEGTIIVTNGDVPLLTDHTLSALLDAHVEVPTAVTVLTMRLDDPTGYGRIVRNEEGEV
TAIVEQKDASAEVQAIDEVNSGVFAFDAAILRSALAELKSDNAQGELYLTDVLGIARGEGHPVRAHTAADARELAGVNDR
VQLAEAGAELNRRTVIAAMRGGATIVDPATTWIDVEVSIGRDVIIHPGTQLKGETVIGDRVEVGPDTTLTNMTIGDGASV
IRTHGFDSTIGENATVGPFTYIRPGTTLGPEGKLGGFVETKKATIGRGSKVPHLTYVGDATIGEESNIGASSVFVNYDGE
NKHHTTIGSHVRTGSDTMFIAPVTVGDGAYSGAGTVIKDDVPPGALAVSGGRQRNIEGWVQKKRPGTAAAQAAEAAQNVH
NQEG

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=461, Percent_Identity=41.2147505422993, Blast_Score=315, Evalue=6e-87,
Organism=Saccharomyces cerevisiae, GI6320148, Length=380, Percent_Identity=23.9473684210526, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 50458; Mature: 50327

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASDFSSAVVVLAAGAGTRMKSDLQKTLHSIGGRSLISHSLHAAAGLNPEHIVAVIGHG
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHEEEEEECC
RDQVGPAVAQVAEELDREVLIAIQEEQNGTGHAVQCAMDQLEGFEGTIIVTNGDVPLLTD
CCCCCHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEH
HTLSALLDAHVEVPTAVTVLTMRLDDPTGYGRIVRNEEGEVTAIVEQKDASAEVQAIDEV
HHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHH
NSGVFAFDAAILRSALAELKSDNAQGELYLTDVLGIARGEGHPVRAHTAADARELAGVND
CCCEEEHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCEEEECHHHHHHHCCCCC
RVQLAEAGAELNRRTVIAAMRGGATIVDPATTWIDVEVSIGRDVIIHPGTQLKGETVIGD
HHHHHHHCCCCCCEEEEEEECCCCEEECCCCEEEEEEEECCCEEEECCCCCCCCCEEECC
RVEVGPDTTLTNMTIGDGASVIRTHGFDSTIGENATVGPFTYIRPGTTLGPEGKLGGFVE
EEECCCCCEEEEEEECCCCCEEEECCCCCCCCCCCEECCEEEECCCCCCCCCCCCCCEEE
TKKATIGRGSKVPHLTYVGDATIGEESNIGASSVFVNYDGENKHHTTIGSHVRTGSDTMF
ECHHHCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEECCCCCEEECCCCEEE
IAPVTVGDGAYSGAGTVIKDDVPPGALAVSGGRQRNIEGWVQKKRPGTAAAQAAEAAQNV
EEEEEECCCCCCCCCCEEECCCCCCEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHHHH
HNQEG
CCCCC
>Mature Secondary Structure 
SASDFSSAVVVLAAGAGTRMKSDLQKTLHSIGGRSLISHSLHAAAGLNPEHIVAVIGHG
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHEEEEEECC
RDQVGPAVAQVAEELDREVLIAIQEEQNGTGHAVQCAMDQLEGFEGTIIVTNGDVPLLTD
CCCCCHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEH
HTLSALLDAHVEVPTAVTVLTMRLDDPTGYGRIVRNEEGEVTAIVEQKDASAEVQAIDEV
HHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHH
NSGVFAFDAAILRSALAELKSDNAQGELYLTDVLGIARGEGHPVRAHTAADARELAGVND
CCCEEEHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCEEEECHHHHHHHCCCCC
RVQLAEAGAELNRRTVIAAMRGGATIVDPATTWIDVEVSIGRDVIIHPGTQLKGETVIGD
HHHHHHHCCCCCCEEEEEEECCCCEEECCCCEEEEEEEECCCEEEECCCCCCCCCEEECC
RVEVGPDTTLTNMTIGDGASVIRTHGFDSTIGENATVGPFTYIRPGTTLGPEGKLGGFVE
EEECCCCCEEEEEEECCCCCEEEECCCCCCCCCCCEECCEEEECCCCCCCCCCCCCCEEE
TKKATIGRGSKVPHLTYVGDATIGEESNIGASSVFVNYDGENKHHTTIGSHVRTGSDTMF
ECHHHCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEECCCCCEEECCCCEEE
IAPVTVGDGAYSGAGTVIKDDVPPGALAVSGGRQRNIEGWVQKKRPGTAAAQAAEAAQNV
EEEEEECCCCCCCCCCEEECCCCCCEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHHHH
HNQEG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA