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The map label for this gene is recQ [H]

Identifier: 62389784

GI number: 62389784

Start: 950260

End: 952311

Strand: Direct

Name: recQ [H]

Synonym: cg1018

Alternate gene names: 62389784

Gene position: 950260-952311 (Clockwise)

Preceding gene: 62389783

Following gene: 62389788

Centisome position: 28.95

GC content: 54.04

Gene sequence:

>2052_bases
ATGAACGCAACGAGGGAAGAAGCCAACAACTTACTAGCTGGAATCGCCGGACCTGGCGCACAGCTCCGCGATGATCAATG
GGTAGCAATTGATGCATTGGTAAACCAACGCAAACGCATGCTGGTGGTGCAAAGGACCGGTTGGGGTAAATCAGCCGTCT
ACTTCATCGCCGCCAAACTGTTAAGAGCACGCGGTGCGGGCGCAGCCGTGATTATTTCTCCACTACTAGCCCTCATGCGT
AACCAGGTGGCGTCCGCCGAACGCGCCGGGATTAAGGCAGCGACACTCAACAGTGCCAATATGACGGAATGGGAAACCAT
CCAGCAACAAGTCGTTTCAGGCGACGCCGATGTGCTGTTAATTTCACCTGAACGCCTCAACAACCCAGACTTTAGAGACA
CCATTTTGCCTCGACTAGCAGCTGAAACAGGCCTAGTGGTGGTCGATGAAGCCCACTGTATTTCCGACTGGGGTCACGAT
TTCCGCCCCGATTATCGCCGCATCCGCGACCTGTTAGCGGGACTTGCGCCCAATATTCCCGTGCTAGCAACCACAGCCAC
CGCCAATGACCGCGTGGTTGAAGATGTCCGTGCCCAACTAGGAGATGGCACAGGTTTGCTTCGTGGTGGGCTAGACCGTG
AATCCCTTTACCTATCAGTGGTGAACCTGCTCAACCCCACCGAACGCCCAGCTTGGCTTGCCACCCACCTCAAAGAACTG
ACGGGTTCGGGCATCATTTACTGCCTCACTGTGTCAGCTGCACATGATCTTGCCGATGCACTTAATTCTGTTGGATGGAA
TGTTGCCGCGTACACCGGTCGAACCGAAGCAGGAGAGCGCGAACGTTTAGAACATGCCTTGATCAACAACGAGATCAAAG
CACTAGTAGCAACCTCTGCACTGGGAATGGGCTTTGACAAACCTGACCTTGGATTTGTTGTGCACATGGGCAGCCCCAGC
TCACCGGTGTCTTATTACCAGCAGATTGGTCGCGCCGGGCGCGGCACCGCTCGTGCCGATGTCATCCTGCTGCCAGGAAC
TGAAGACAAAGAGATCTGGGAGTACTTTGCATCAGTATCGTTCCCACGCGAAGAGGTAGTCCGCCAACTGCTTGCGGTGT
TAACCGATGAGGCGCAATCCACTGTCAAATTGGAATCACAAGTAGATCTTTCCCGATCACGCCTTGAACAAGTACTTAAA
GTGCTAGACGTAGATGGCGCAGTCAAACGTGTACGTGGCGGATGGGTCTCCACCGGGCAAGAGTGGATCTACGATGCGGA
ACGCTACGCAGGACTTGAACAAGCAAGGAAAATTGAACAGCAAAGCATGGTGAACTACCAGAACACCACTGAGTGCCGCA
TGCTGTACCTCCGCAAAGAACTAGACGATGTGGAGGCAACTACTCCGTGCGGGCGCTGCGACAATTGCACGGGCAAAACG
TGGGGGCTCGACACCGATGCCTCGATCACTTTGAAAGTGGACCAACAGCTTCAAACACCCGGAGTGAAAATAGCCCCACG
AAAAATGTGGCCGACTGGCATTAGTGTCAGAGGAAAAATCGCAGGGCTAGAAGAAGGACGAGCACTGGGACGACTCAATG
ACATTGCCCGTGGACCTGCACTAAAGGCCCTGCTGGACAGCGGAGCTTATTCTGATGATCCATGGATGGCACGCATCATC
GAAGTGCTGAAAAACTGGGATTGGACCAACCGGCCTGCCAACGTGGTCGCTCTCGGCAATACCAACTTTGGATCAACTGA
GATGATCATCCAGGTAGCTCAATCAATCGCAGCGGTGGGACGAATGAACTTTGCGGGTGTACTTCCCGCCGCGCCGGGTG
CTGAAGAAGTCATGGCTCAGAATTCCGCATACCGAGTAGAAGCCCTATTGAAACAATGGGACTGGTCGCAAGGCTTGCAA
CTAGTTCCCGGTCCCATTTTGCTGGTGACAGACCTTATTGATACTGGCTGGTCGGTGACAGTTGCAGGAAATGGCATTGC
GCAGCGGACCTCAGAGAAGGTGCTGCCGTTCGCTTTAGCGAGTAGGGGATAG

Upstream 100 bases:

>100_bases
CGAGCAGGTTGATCAGAAACATCTGATTGACCTGCTCTTATTAGTTGGCGGGGGTGGGGCGGGGGAGTGTGTGTCCACCC
CGTGGTGTTAGGTGGAAGGC

Downstream 100 bases:

>100_bases
GTGCTCTGGGACGAGAGCAATTGGACGCACTGGGAAACTAGCACCATCTTTTGGAACTGGCCAAGGACAAGCAATCATCG
CACCCGTTGCAGGAACCTTG

Product: ATP-dependent DNA helicase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MNATREEANNLLAGIAGPGAQLRDDQWVAIDALVNQRKRMLVVQRTGWGKSAVYFIAAKLLRARGAGAAVIISPLLALMR
NQVASAERAGIKAATLNSANMTEWETIQQQVVSGDADVLLISPERLNNPDFRDTILPRLAAETGLVVVDEAHCISDWGHD
FRPDYRRIRDLLAGLAPNIPVLATTATANDRVVEDVRAQLGDGTGLLRGGLDRESLYLSVVNLLNPTERPAWLATHLKEL
TGSGIIYCLTVSAAHDLADALNSVGWNVAAYTGRTEAGERERLEHALINNEIKALVATSALGMGFDKPDLGFVVHMGSPS
SPVSYYQQIGRAGRGTARADVILLPGTEDKEIWEYFASVSFPREEVVRQLLAVLTDEAQSTVKLESQVDLSRSRLEQVLK
VLDVDGAVKRVRGGWVSTGQEWIYDAERYAGLEQARKIEQQSMVNYQNTTECRMLYLRKELDDVEATTPCGRCDNCTGKT
WGLDTDASITLKVDQQLQTPGVKIAPRKMWPTGISVRGKIAGLEEGRALGRLNDIARGPALKALLDSGAYSDDPWMARII
EVLKNWDWTNRPANVVALGNTNFGSTEMIIQVAQSIAAVGRMNFAGVLPAAPGAEEVMAQNSAYRVEALLKQWDWSQGLQ
LVPGPILLVTDLIDTGWSVTVAGNGIAQRTSEKVLPFALASRG

Sequences:

>Translated_683_residues
MNATREEANNLLAGIAGPGAQLRDDQWVAIDALVNQRKRMLVVQRTGWGKSAVYFIAAKLLRARGAGAAVIISPLLALMR
NQVASAERAGIKAATLNSANMTEWETIQQQVVSGDADVLLISPERLNNPDFRDTILPRLAAETGLVVVDEAHCISDWGHD
FRPDYRRIRDLLAGLAPNIPVLATTATANDRVVEDVRAQLGDGTGLLRGGLDRESLYLSVVNLLNPTERPAWLATHLKEL
TGSGIIYCLTVSAAHDLADALNSVGWNVAAYTGRTEAGERERLEHALINNEIKALVATSALGMGFDKPDLGFVVHMGSPS
SPVSYYQQIGRAGRGTARADVILLPGTEDKEIWEYFASVSFPREEVVRQLLAVLTDEAQSTVKLESQVDLSRSRLEQVLK
VLDVDGAVKRVRGGWVSTGQEWIYDAERYAGLEQARKIEQQSMVNYQNTTECRMLYLRKELDDVEATTPCGRCDNCTGKT
WGLDTDASITLKVDQQLQTPGVKIAPRKMWPTGISVRGKIAGLEEGRALGRLNDIARGPALKALLDSGAYSDDPWMARII
EVLKNWDWTNRPANVVALGNTNFGSTEMIIQVAQSIAAVGRMNFAGVLPAAPGAEEVMAQNSAYRVEALLKQWDWSQGLQ
LVPGPILLVTDLIDTGWSVTVAGNGIAQRTSEKVLPFALASRG
>Mature_683_residues
MNATREEANNLLAGIAGPGAQLRDDQWVAIDALVNQRKRMLVVQRTGWGKSAVYFIAAKLLRARGAGAAVIISPLLALMR
NQVASAERAGIKAATLNSANMTEWETIQQQVVSGDADVLLISPERLNNPDFRDTILPRLAAETGLVVVDEAHCISDWGHD
FRPDYRRIRDLLAGLAPNIPVLATTATANDRVVEDVRAQLGDGTGLLRGGLDRESLYLSVVNLLNPTERPAWLATHLKEL
TGSGIIYCLTVSAAHDLADALNSVGWNVAAYTGRTEAGERERLEHALINNEIKALVATSALGMGFDKPDLGFVVHMGSPS
SPVSYYQQIGRAGRGTARADVILLPGTEDKEIWEYFASVSFPREEVVRQLLAVLTDEAQSTVKLESQVDLSRSRLEQVLK
VLDVDGAVKRVRGGWVSTGQEWIYDAERYAGLEQARKIEQQSMVNYQNTTECRMLYLRKELDDVEATTPCGRCDNCTGKT
WGLDTDASITLKVDQQLQTPGVKIAPRKMWPTGISVRGKIAGLEEGRALGRLNDIARGPALKALLDSGAYSDDPWMARII
EVLKNWDWTNRPANVVALGNTNFGSTEMIIQVAQSIAAVGRMNFAGVLPAAPGAEEVMAQNSAYRVEALLKQWDWSQGLQ
LVPGPILLVTDLIDTGWSVTVAGNGIAQRTSEKVLPFALASRG

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI110735439, Length=317, Percent_Identity=33.4384858044164, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI169218196, Length=317, Percent_Identity=33.4384858044164, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI14591902, Length=325, Percent_Identity=32.3076923076923, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI14591904, Length=325, Percent_Identity=32.3076923076923, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI4557365, Length=347, Percent_Identity=32.8530259365994, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI51242943, Length=329, Percent_Identity=33.1306990881459, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI51242947, Length=329, Percent_Identity=33.1306990881459, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI148612816, Length=325, Percent_Identity=33.5384615384615, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI284005309, Length=332, Percent_Identity=31.9277108433735, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI45446747, Length=324, Percent_Identity=25.3086419753086, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI45446743, Length=324, Percent_Identity=25.3086419753086, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI48994977, Length=328, Percent_Identity=37.5, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1787016, Length=364, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564293, Length=382, Percent_Identity=31.9371727748691, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI71987997, Length=333, Percent_Identity=33.9339339339339, Blast_Score=165, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI71987993, Length=332, Percent_Identity=33.433734939759, Blast_Score=165, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17552866, Length=364, Percent_Identity=31.043956043956, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25145561, Length=330, Percent_Identity=32.4242424242424, Blast_Score=152, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6323844, Length=321, Percent_Identity=34.5794392523364, Blast_Score=176, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24646066, Length=321, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI62472181, Length=325, Percent_Identity=31.0769230769231, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24664230, Length=325, Percent_Identity=31.0769230769231, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24664226, Length=325, Percent_Identity=31.0769230769231, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21358123, Length=365, Percent_Identity=32.3287671232877, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24662330, Length=329, Percent_Identity=23.4042553191489, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 74321; Mature: 74321

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATREEANNLLAGIAGPGAQLRDDQWVAIDALVNQRKRMLVVQRTGWGKSAVYFIAAKL
CCCCHHHHHHHEEECCCCCCCCCCCCEEEHHHHHCCCCEEEEEEECCCCCHHHHHHHHHH
LRARGAGAAVIISPLLALMRNQVASAERAGIKAATLNSANMTEWETIQQQVVSGDADVLL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEE
ISPERLNNPDFRDTILPRLAAETGLVVVDEAHCISDWGHDFRPDYRRIRDLLAGLAPNIP
ECHHHCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
VLATTATANDRVVEDVRAQLGDGTGLLRGGLDRESLYLSVVNLLNPTERPAWLATHLKEL
EEEEECCCCHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TGSGIIYCLTVSAAHDLADALNSVGWNVAAYTGRTEAGERERLEHALINNEIKALVATSA
CCCCEEEEEEEHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGMGFDKPDLGFVVHMGSPSSPVSYYQQIGRAGRGTARADVILLPGTEDKEIWEYFASVS
HCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHCC
FPREEVVRQLLAVLTDEAQSTVKLESQVDLSRSRLEQVLKVLDVDGAVKRVRGGWVSTGQ
CCHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCH
EWIYDAERYAGLEQARKIEQQSMVNYQNTTECRMLYLRKELDDVEATTPCGRCDNCTGKT
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
WGLDTDASITLKVDQQLQTPGVKIAPRKMWPTGISVRGKIAGLEEGRALGRLNDIARGPA
CCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCHH
LKALLDSGAYSDDPWMARIIEVLKNWDWTNRPANVVALGNTNFGSTEMIIQVAQSIAAVG
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
RMNFAGVLPAAPGAEEVMAQNSAYRVEALLKQWDWSQGLQLVPGPILLVTDLIDTGWSVT
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCEECCCCCEEHHHHHHCCCEEE
VAGNGIAQRTSEKVLPFALASRG
EECCCHHHHHHCCCCCHHHCCCC
>Mature Secondary Structure
MNATREEANNLLAGIAGPGAQLRDDQWVAIDALVNQRKRMLVVQRTGWGKSAVYFIAAKL
CCCCHHHHHHHEEECCCCCCCCCCCCEEEHHHHHCCCCEEEEEEECCCCCHHHHHHHHHH
LRARGAGAAVIISPLLALMRNQVASAERAGIKAATLNSANMTEWETIQQQVVSGDADVLL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEE
ISPERLNNPDFRDTILPRLAAETGLVVVDEAHCISDWGHDFRPDYRRIRDLLAGLAPNIP
ECHHHCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
VLATTATANDRVVEDVRAQLGDGTGLLRGGLDRESLYLSVVNLLNPTERPAWLATHLKEL
EEEEECCCCHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TGSGIIYCLTVSAAHDLADALNSVGWNVAAYTGRTEAGERERLEHALINNEIKALVATSA
CCCCEEEEEEEHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGMGFDKPDLGFVVHMGSPSSPVSYYQQIGRAGRGTARADVILLPGTEDKEIWEYFASVS
HCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHCC
FPREEVVRQLLAVLTDEAQSTVKLESQVDLSRSRLEQVLKVLDVDGAVKRVRGGWVSTGQ
CCHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCH
EWIYDAERYAGLEQARKIEQQSMVNYQNTTECRMLYLRKELDDVEATTPCGRCDNCTGKT
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
WGLDTDASITLKVDQQLQTPGVKIAPRKMWPTGISVRGKIAGLEEGRALGRLNDIARGPA
CCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCHH
LKALLDSGAYSDDPWMARIIEVLKNWDWTNRPANVVALGNTNFGSTEMIIQVAQSIAAVG
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
RMNFAGVLPAAPGAEEVMAQNSAYRVEALLKQWDWSQGLQLVPGPILLVTDLIDTGWSVT
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCEECCCCCEEHHHHHHCCCEEE
VAGNGIAQRTSEKVLPFALASRG
EECCCHHHHHHCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]