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The map label for this gene is yciC [H]

Identifier: 62389581

GI number: 62389581

Start: 711990

End: 713078

Strand: Reverse

Name: yciC [H]

Synonym: cg0794

Alternate gene names: 62389581

Gene position: 713078-711990 (Counterclockwise)

Preceding gene: 62389586

Following gene: 62389575

Centisome position: 21.72

GC content: 58.59

Gene sequence:

>1089_bases
ATGGCCACAACGACCCCAGTCACCGTGCTATCAGGATTTCTCGGCTCCGGAAAAACCACATTGCTCAACCAGATCCTCCA
CCACCGAGGATCCCGGAAAATCGCAGTCATTGTCAACGATTTTTCAGAAATCAACATCGACGCAGCCCTCATCGCATCCG
AAGGCCACCTCACCCGCGGCGAAGACCGCTTCGTGGAACTGACCAACGGATGCATCTGCTGCACCCTGCGCGAAGACCTC
GTGGATTCCGTCGGCGAACTCGCCAGCAGCGACCGCTTCGACCACATCGTCATCGAATCCACGGGTATCTCCGAACCAAT
GCCGGTAGCCGCCACATTTGAATGGCAGTGGGATGACGGCACCCGCCTGGCTGACAAAGCACCGATCGACACCATGGTCA
CCCTGGTCGATGCCACCCAATTCATCGACCTCATCCGCAAAAACACCTCCCTCACCGAGGCTGACATGGGCGCAACCGAG
GACGATGAACGCACCATCGCCGACCTACTCACCGATCAAATCGAGTTCGCCGACCGCATCTACATCACCAAATCCGACCT
GGTGGACCGCACTGTCCTCGAGCAAACCCGCGCACTAATCGCCAGCATGAGTCCACGCGCCCGCATTGACTTACTCATCG
ATGGCCTCAATGACGGCTCCCCCATCACCGACGACATCCTCGGAGCTTTCCTCTACGACGAAGCCACCGCCCGCGCCTAC
GAGGGCTACACGGAAGAACTCGAAAACCCGCACACTCCCGAAACCGAGGAATACGGCATCAGTTCCGTGGTATTCCGCTC
TGACCGGCCGTTCAACAAGGATCGCCTACTTCAGGTACTGCGTTCCACCACTGGACTCGTTCGCTCCAAAGGCTATTGCT
GGATCGCTGATCACCTCAACATCGTCCAGGTCTGGCACCAAGCCGGCCCCAATTTGAGCATTCGCCCGGCCGCCTATTGG
GCCAATTCAGAGATCACCCCCGGCACTGAATTGGTCCTGATCGGCATCCACATCGACGGCCCCACCTTGCTCGCACTGCT
ACAAGGCGCGACGCTTACCGATGCGGAAGTGGCGGCACTGGTTTTGTGA

Upstream 100 bases:

>100_bases
GAAGGTCAAAAAACTTGACTTTATTGAAAACAATTTCCATTAAGAAGTGTACACTTGCGTCGACTCTATTGAAAATGATT
CCCAAAAGGAGGGCTTTCAC

Downstream 100 bases:

>100_bases
GTTCCTCAAGTCCGTGAATTCCACAGTGACTTCGCTCGTAAAGGCAGCGTAAAGGCAGTGACCCCGAAGGAATTTCCGGG
GCTCTTCCTCAAGCTCAGAC

Product: cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MATTTPVTVLSGFLGSGKTTLLNQILHHRGSRKIAVIVNDFSEINIDAALIASEGHLTRGEDRFVELTNGCICCTLREDL
VDSVGELASSDRFDHIVIESTGISEPMPVAATFEWQWDDGTRLADKAPIDTMVTLVDATQFIDLIRKNTSLTEADMGATE
DDERTIADLLTDQIEFADRIYITKSDLVDRTVLEQTRALIASMSPRARIDLLIDGLNDGSPITDDILGAFLYDEATARAY
EGYTEELENPHTPETEEYGISSVVFRSDRPFNKDRLLQVLRSTTGLVRSKGYCWIADHLNIVQVWHQAGPNLSIRPAAYW
ANSEITPGTELVLIGIHIDGPTLLALLQGATLTDAEVAALVL

Sequences:

>Translated_362_residues
MATTTPVTVLSGFLGSGKTTLLNQILHHRGSRKIAVIVNDFSEINIDAALIASEGHLTRGEDRFVELTNGCICCTLREDL
VDSVGELASSDRFDHIVIESTGISEPMPVAATFEWQWDDGTRLADKAPIDTMVTLVDATQFIDLIRKNTSLTEADMGATE
DDERTIADLLTDQIEFADRIYITKSDLVDRTVLEQTRALIASMSPRARIDLLIDGLNDGSPITDDILGAFLYDEATARAY
EGYTEELENPHTPETEEYGISSVVFRSDRPFNKDRLLQVLRSTTGLVRSKGYCWIADHLNIVQVWHQAGPNLSIRPAAYW
ANSEITPGTELVLIGIHIDGPTLLALLQGATLTDAEVAALVL
>Mature_361_residues
ATTTPVTVLSGFLGSGKTTLLNQILHHRGSRKIAVIVNDFSEINIDAALIASEGHLTRGEDRFVELTNGCICCTLREDLV
DSVGELASSDRFDHIVIESTGISEPMPVAATFEWQWDDGTRLADKAPIDTMVTLVDATQFIDLIRKNTSLTEADMGATED
DERTIADLLTDQIEFADRIYITKSDLVDRTVLEQTRALIASMSPRARIDLLIDGLNDGSPITDDILGAFLYDEATARAYE
GYTEELENPHTPETEEYGISSVVFRSDRPFNKDRLLQVLRSTTGLVRSKGYCWIADHLNIVQVWHQAGPNLSIRPAAYWA
NSEITPGTELVLIGIHIDGPTLLALLQGATLTDAEVAALVL

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=223, Percent_Identity=31.8385650224215, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI126722884, Length=386, Percent_Identity=26.9430051813472, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI223941779, Length=213, Percent_Identity=31.924882629108, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI146231952, Length=386, Percent_Identity=27.720207253886, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI148727351, Length=386, Percent_Identity=26.9430051813472, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI223941776, Length=209, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI119120938, Length=142, Percent_Identity=35.2112676056338, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI87082430, Length=358, Percent_Identity=27.9329608938547, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788499, Length=196, Percent_Identity=29.0816326530612, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=209, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 39744; Mature: 39613

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTPVTVLSGFLGSGKTTLLNQILHHRGSRKIAVIVNDFSEINIDAALIASEGHLTRG
CCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCC
EDRFVELTNGCICCTLREDLVDSVGELASSDRFDHIVIESTGISEPMPVAATFEWQWDDG
CCCEEEECCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEEECCCC
TRLADKAPIDTMVTLVDATQFIDLIRKNTSLTEADMGATEDDERTIADLLTDQIEFADRI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEE
YITKSDLVDRTVLEQTRALIASMSPRARIDLLIDGLNDGSPITDDILGAFLYDEATARAY
EEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
EGYTEELENPHTPETEEYGISSVVFRSDRPFNKDRLLQVLRSTTGLVRSKGYCWIADHLN
CCHHHHHCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCH
IVQVWHQAGPNLSIRPAAYWANSEITPGTELVLIGIHIDGPTLLALLQGATLTDAEVAAL
HHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCHHHHHHHCCCCCCCHHHHEE
VL
EC
>Mature Secondary Structure 
ATTTPVTVLSGFLGSGKTTLLNQILHHRGSRKIAVIVNDFSEINIDAALIASEGHLTRG
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCC
EDRFVELTNGCICCTLREDLVDSVGELASSDRFDHIVIESTGISEPMPVAATFEWQWDDG
CCCEEEECCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEEECCCC
TRLADKAPIDTMVTLVDATQFIDLIRKNTSLTEADMGATEDDERTIADLLTDQIEFADRI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEE
YITKSDLVDRTVLEQTRALIASMSPRARIDLLIDGLNDGSPITDDILGAFLYDEATARAY
EEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
EGYTEELENPHTPETEEYGISSVVFRSDRPFNKDRLLQVLRSTTGLVRSKGYCWIADHLN
CCHHHHHCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCH
IVQVWHQAGPNLSIRPAAYWANSEITPGTELVLIGIHIDGPTLLALLQGATLTDAEVAAL
HHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCHHHHHHHCCCCCCCHHHHEE
VL
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]