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The map label for this gene is pmmB [C]

Identifier: 62389575

GI number: 62389575

Start: 701854

End: 703446

Strand: Reverse

Name: pmmB [C]

Synonym: cg0788

Alternate gene names: 62389575

Gene position: 703446-701854 (Counterclockwise)

Preceding gene: 62389581

Following gene: 62389572

Centisome position: 21.43

GC content: 54.68

Gene sequence:

>1593_bases
ATGGACGAGTCTCGTCAGCTTAGTTTCGGCACAGCAGGGTTGCGTGCACCAGTTGGCCCGGCGCGCCATCAGATGAATGT
TTTGCAGGTAACCAGAACTACAGCAGGTGTTGCTAGTTGGTTGGCAGAACGTGCGGCACTAAATCCAGTGCCGCATTTGG
TTCCTGAGGATGAAACAGGAATCGGCAGGGCGTTGTATCCCCAAGATGGTCCGTTGCGGGTCGTTGTGGGGTATGACGCT
CGCTATGGTTCGCATACTTTTGCTGCAACCACTGCGGAGGTGTTCGCGGGTGCTGGTTTTGAGGTGACGTTGCTCCCCAC
GCCTAGCCCTACGCCGTTGATTCCGTGGTTGGTGAACAAGCATGGGTTGGATGCGGGCGTTCAGATCACGGCTTCGCATA
ATGGTGCGGCGGACAATGGCTACAAGGTGTTTTTGTCTAATGGTCGCCAGCTTTATTCTGAACTGGAGCCTGAGCTTGAG
GCGCATATCAATGCTGTGGAAGATCCGATTCGGGTTCCTCGGGTGACGGTGCGCCCCACTGCTGATCAGCTGCGTCGATA
TGTTGATGAGATGGTGTCGTTGGTGACTCCTGATCAGGCTGATTTGTTGCGGGTGAATTCTGAGCGGGGCAATCTTCGCG
TGGTGTATACCGCTCTGCATGGTGTGGGTGGCCGCGCGATGGCCAATGCTTTCCAATTTGCTGGTTTTCCCCATACTCAT
GGCGTGAAGGCTCAGCAGTATCCTGATCCCACCTTCCCCACTGTGGCGTTCCCCAATCCGGAAGAGCCTTCTGCGATTGA
GTTGTTGTTGGAACGCGCAAAGGAAAAGAACGCTGACATTTTGTTTGCGCTTGATCCTGATGCCGATCGTTGTGCTGTGG
GTATTCGTACCGCTGATGGCGGCCACCGAATGCTCTCTGGCGATGAGGTGGGCACACTTTTGGCTACTCGTTTGGTTCCG
GAGTATTCCGGTGAAGGCCCACGTCCCGTGGTTGCCACCACGGTGGTGTCTTCGCAGCTTCTGGGTATCATCGCCGAGGA
TAAAGGGTGGGATTATTCCGAGACACTGACGGGATTCAAAAATCTGTCGAGGGCTGCCGATGGTCTCGACGGACCGCTTG
CTTTCGCTTATGAGGAAGCTGTGGGCACCTGCCCGGTTCCAGATGTCGTGCCGGATAAGGACGGCATCTCTACAGCGTTG
TTCATGGCGTCGTGGGCTGCCGAACTGAAGGCTCAGGGCGCAAGCCTGCAGCAAAAACTCAATGAGTTGTATCGCCGATA
TGGGTATTTTGCGTCCTCGCAAATTGCTGTGCGCACGAGCAGTCCACGCGAGTTAGTTGATCACTGGATTGCGCATCCTC
AGCAAGAACTCATTGGAGTGTCTGTCACCCCACATATTCTTCCTGAAAAACAGGGCATTGCTTTGCATGGCCAGGTGGGG
CATGTGCATATCCGTGCTATTGGTCGAGTCTCTGGAACTGAGGCGAAAGCCAAGCTCTATTTGGAAGTTGGTCAGGCCAG
CTCCCATGATGAAGCAGCTCAGTTGTTGCATCAGCTGGAGGATGAAGTCCAAAGCTGGTTGAGCAAGCTTTAG

Upstream 100 bases:

>100_bases
AATACCTTTCTGTTTTGTCCGCAGGCGTATCAGGAAAACCTGCAGCGCGGTAGAGTCGAGTCTAATAGTGATCCCACGAA
AACAAAGGATCGGGGTGTTC

Downstream 100 bases:

>100_bases
TTTCCTGGCTGCTCGCGGTTGCGGGTGAGCCGGAGGTCTGCGTCGAAAAGCAGTGGATCTTTTTCTGAAGGCCACCGCAC
GTCAATGGCGGCGGTTTCGT

Product: phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MDESRQLSFGTAGLRAPVGPARHQMNVLQVTRTTAGVASWLAERAALNPVPHLVPEDETGIGRALYPQDGPLRVVVGYDA
RYGSHTFAATTAEVFAGAGFEVTLLPTPSPTPLIPWLVNKHGLDAGVQITASHNGAADNGYKVFLSNGRQLYSELEPELE
AHINAVEDPIRVPRVTVRPTADQLRRYVDEMVSLVTPDQADLLRVNSERGNLRVVYTALHGVGGRAMANAFQFAGFPHTH
GVKAQQYPDPTFPTVAFPNPEEPSAIELLLERAKEKNADILFALDPDADRCAVGIRTADGGHRMLSGDEVGTLLATRLVP
EYSGEGPRPVVATTVVSSQLLGIIAEDKGWDYSETLTGFKNLSRAADGLDGPLAFAYEEAVGTCPVPDVVPDKDGISTAL
FMASWAAELKAQGASLQQKLNELYRRYGYFASSQIAVRTSSPRELVDHWIAHPQQELIGVSVTPHILPEKQGIALHGQVG
HVHIRAIGRVSGTEAKAKLYLEVGQASSHDEAAQLLHQLEDEVQSWLSKL

Sequences:

>Translated_530_residues
MDESRQLSFGTAGLRAPVGPARHQMNVLQVTRTTAGVASWLAERAALNPVPHLVPEDETGIGRALYPQDGPLRVVVGYDA
RYGSHTFAATTAEVFAGAGFEVTLLPTPSPTPLIPWLVNKHGLDAGVQITASHNGAADNGYKVFLSNGRQLYSELEPELE
AHINAVEDPIRVPRVTVRPTADQLRRYVDEMVSLVTPDQADLLRVNSERGNLRVVYTALHGVGGRAMANAFQFAGFPHTH
GVKAQQYPDPTFPTVAFPNPEEPSAIELLLERAKEKNADILFALDPDADRCAVGIRTADGGHRMLSGDEVGTLLATRLVP
EYSGEGPRPVVATTVVSSQLLGIIAEDKGWDYSETLTGFKNLSRAADGLDGPLAFAYEEAVGTCPVPDVVPDKDGISTAL
FMASWAAELKAQGASLQQKLNELYRRYGYFASSQIAVRTSSPRELVDHWIAHPQQELIGVSVTPHILPEKQGIALHGQVG
HVHIRAIGRVSGTEAKAKLYLEVGQASSHDEAAQLLHQLEDEVQSWLSKL
>Mature_530_residues
MDESRQLSFGTAGLRAPVGPARHQMNVLQVTRTTAGVASWLAERAALNPVPHLVPEDETGIGRALYPQDGPLRVVVGYDA
RYGSHTFAATTAEVFAGAGFEVTLLPTPSPTPLIPWLVNKHGLDAGVQITASHNGAADNGYKVFLSNGRQLYSELEPELE
AHINAVEDPIRVPRVTVRPTADQLRRYVDEMVSLVTPDQADLLRVNSERGNLRVVYTALHGVGGRAMANAFQFAGFPHTH
GVKAQQYPDPTFPTVAFPNPEEPSAIELLLERAKEKNADILFALDPDADRCAVGIRTADGGHRMLSGDEVGTLLATRLVP
EYSGEGPRPVVATTVVSSQLLGIIAEDKGWDYSETLTGFKNLSRAADGLDGPLAFAYEEAVGTCPVPDVVPDKDGISTAL
FMASWAAELKAQGASLQQKLNELYRRYGYFASSQIAVRTSSPRELVDHWIAHPQQELIGVSVTPHILPEKQGIALHGQVG
HVHIRAIGRVSGTEAKAKLYLEVGQASSHDEAAQLLHQLEDEVQSWLSKL

Specific function: Involved In The Biosynthesis Of The Capsular Polysaccharide Colanic Acid. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI31377548, Length=567, Percent_Identity=31.5696649029982, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI63055049, Length=449, Percent_Identity=33.630289532294, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71993870, Length=439, Percent_Identity=33.4851936218679, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI71993878, Length=295, Percent_Identity=32.5423728813559, Blast_Score=137, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323934, Length=584, Percent_Identity=29.2808219178082, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI20129809, Length=455, Percent_Identity=34.0659340659341, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24651977, Length=455, Percent_Identity=34.0659340659341, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24653722, Length=469, Percent_Identity=30.9168443496802, Blast_Score=190, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 57256; Mature: 57256

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESRQLSFGTAGLRAPVGPARHQMNVLQVTRTTAGVASWLAERAALNPVPHLVPEDETG
CCCCCCEECCCCCCCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
IGRALYPQDGPLRVVVGYDARYGSHTFAATTAEVFAGAGFEVTLLPTPSPTPLIPWLVNK
CCCEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCC
HGLDAGVQITASHNGAADNGYKVFLSNGRQLYSELEPELEAHINAVEDPIRVPRVTVRPT
CCCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHCCHHHHHHHHHHCCCCCCCEEEECCC
ADQLRRYVDEMVSLVTPDQADLLRVNSERGNLRVVYTALHGVGGRAMANAFQFAGFPHTH
HHHHHHHHHHHHHHCCCCCHHEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCC
GVKAQQYPDPTFPTVAFPNPEEPSAIELLLERAKEKNADILFALDPDADRCAVGIRTADG
CCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCC
GHRMLSGDEVGTLLATRLVPEYSGEGPRPVVATTVVSSQLLGIIAEDKGWDYSETLTGFK
CCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHEEEECCCCCCHHHHHHHHH
NLSRAADGLDGPLAFAYEEAVGTCPVPDVVPDKDGISTALFMASWAAELKAQGASLQQKL
HHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
NELYRRYGYFASSQIAVRTSSPRELVDHWIAHPQQELIGVSVTPHILPEKQGIALHGQVG
HHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCCHHHEEEECCCCCCCCCCCEEEECCCC
HVHIRAIGRVSGTEAKAKLYLEVGQASSHDEAAQLLHQLEDEVQSWLSKL
EEEEEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDESRQLSFGTAGLRAPVGPARHQMNVLQVTRTTAGVASWLAERAALNPVPHLVPEDETG
CCCCCCEECCCCCCCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
IGRALYPQDGPLRVVVGYDARYGSHTFAATTAEVFAGAGFEVTLLPTPSPTPLIPWLVNK
CCCEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCC
HGLDAGVQITASHNGAADNGYKVFLSNGRQLYSELEPELEAHINAVEDPIRVPRVTVRPT
CCCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHCCHHHHHHHHHHCCCCCCCEEEECCC
ADQLRRYVDEMVSLVTPDQADLLRVNSERGNLRVVYTALHGVGGRAMANAFQFAGFPHTH
HHHHHHHHHHHHHHCCCCCHHEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCC
GVKAQQYPDPTFPTVAFPNPEEPSAIELLLERAKEKNADILFALDPDADRCAVGIRTADG
CCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCC
GHRMLSGDEVGTLLATRLVPEYSGEGPRPVVATTVVSSQLLGIIAEDKGWDYSETLTGFK
CCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHEEEECCCCCCHHHHHHHHH
NLSRAADGLDGPLAFAYEEAVGTCPVPDVVPDKDGISTALFMASWAAELKAQGASLQQKL
HHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
NELYRRYGYFASSQIAVRTSSPRELVDHWIAHPQQELIGVSVTPHILPEKQGIALHGQVG
HHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCCHHHEEEECCCCCCCCCCCEEEECCCC
HVHIRAIGRVSGTEAKAKLYLEVGQASSHDEAAQLLHQLEDEVQSWLSKL
EEEEEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]