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The map label for this gene is guaB3

Identifier: 62389495

GI number: 62389495

Start: 618434

End: 619558

Strand: Direct

Name: guaB3

Synonym: cg0700

Alternate gene names: NA

Gene position: 618434-619558 (Clockwise)

Preceding gene: 62389494

Following gene: 62389497

Centisome position: 18.84

GC content: 55.47

Gene sequence:

>1125_bases
ATGCGTGACCACGTTGAAATCGGTATCGGCCGTGAGGCACGACGCACCTACAGCTTGGACGATATTTCTGTCGTTTCTAG
CCGCCGCACCCGTTCATCCAAAGATGTCGACACCACTTGGCATATTGACGCCTACAAGTTTGATCTGCCGTTCATGAATC
ACCCAAGTGATGCATTGGCAAGCCCTGAGTTTGTCATTGAAATGGGCAAGCAGGGTGGCCTTGGCGTGATCAACGCTGAG
GGTCTGTGGGGTCGCCATGCTGATCTCGATGAGGCGATCGCAAAGGTGATTGCTGCGTATGAGGAAGGCGACCAGGCTGC
AGCCACTCGCACTCTTCAGGAGCTGCACGCAGCGCCACTGGATACTGAGCTGCTGAGTGAGCGCATTGCGCAGGTTCGTG
ATTCCGGTGAGATCGTTGCTGTGCGCGTGTCTCCACAAAATGTTCGTGAGATCGCACCAATCGTCATCAAGGCAGGTGCT
GATCTGCTGGTTATCCAGGGCACCCTGATCTCTGCAGAGCACGTCAACACCGGTGGAGAGGCCCTGAACCTAAAGGAATT
CATCGGTTCTTTGGATGTTCCTGTCATCGCTGGTGGCGTGAACGATTACACCACCGCGTTGCACATGATGCGTACCGGTG
CTGTGGGCATCATCGTCGGTGGCGGCGAGAACACCAACAGCCTAGCATTGGGCATGGAGGTATCCATGGCCACTGCGATT
GCTGATGTCGCTGCGGCACGTCGTGATTACCTGGATGAGACCGGTGGACGTTACGTGCACATCATTGCAGATGGAAGCAT
TGAAAACTCCGGTGATGTAGTCAAGGCTATTGCCTGTGGCGCAGATGCTGTGGTGCTGGGTTCACCGTTGGCTCGCGCTG
AAGAAGCTGCTGGAAAGGGCTACTTCTGGCCAGCAGTGGCAGCGCACCCTCGTTTCCCACGCGGTGTGGTTACTGAGTCC
GTGGACTTGGATGAGGCAGCACCAAGCTTGGAGCAGATTCTGCATGGTCCGTCTACGATGCCGTGGGGTGTGGAAAACTT
CGAAGGTGGATTAAAGCGTGCGCTGGCTAAGTGTGGCTACACCGATTTGAAGAGCTTCCAAAAGGTAAGCCTGCACGTTA
ACTAG

Upstream 100 bases:

>100_bases
CAGCCCGATTTCTTCATTGAAATCGGGCTGTTTCTGGTTGTGTCGCGTATCTCGGGTAAAGTCTTCGTCGTATACGACCA
TTTAAGGGAGGCCCGTCACA

Downstream 100 bases:

>100_bases
GTGTGTGTACTCGCCTCTTCGCGTTGCATTTTGAGTGGAGGGGCGCGTCGACAAGCATCTTTTTAGGCTCCCACGTGACG
CCGATGCTGGCCGCGATGAC

Product: inosine 5-monophosphate dehydrogenase

Products: xanthosine 5'-phosphate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRDHVEIGIGREARRTYSLDDISVVSSRRTRSSKDVDTTWHIDAYKFDLPFMNHPSDALASPEFVIEMGKQGGLGVINAE
GLWGRHADLDEAIAKVIAAYEEGDQAAATRTLQELHAAPLDTELLSERIAQVRDSGEIVAVRVSPQNVREIAPIVIKAGA
DLLVIQGTLISAEHVNTGGEALNLKEFIGSLDVPVIAGGVNDYTTALHMMRTGAVGIIVGGGENTNSLALGMEVSMATAI
ADVAAARRDYLDETGGRYVHIIADGSIENSGDVVKAIACGADAVVLGSPLARAEEAAGKGYFWPAVAAHPRFPRGVVTES
VDLDEAAPSLEQILHGPSTMPWGVENFEGGLKRALAKCGYTDLKSFQKVSLHVN

Sequences:

>Translated_374_residues
MRDHVEIGIGREARRTYSLDDISVVSSRRTRSSKDVDTTWHIDAYKFDLPFMNHPSDALASPEFVIEMGKQGGLGVINAE
GLWGRHADLDEAIAKVIAAYEEGDQAAATRTLQELHAAPLDTELLSERIAQVRDSGEIVAVRVSPQNVREIAPIVIKAGA
DLLVIQGTLISAEHVNTGGEALNLKEFIGSLDVPVIAGGVNDYTTALHMMRTGAVGIIVGGGENTNSLALGMEVSMATAI
ADVAAARRDYLDETGGRYVHIIADGSIENSGDVVKAIACGADAVVLGSPLARAEEAAGKGYFWPAVAAHPRFPRGVVTES
VDLDEAAPSLEQILHGPSTMPWGVENFEGGLKRALAKCGYTDLKSFQKVSLHVN
>Mature_374_residues
MRDHVEIGIGREARRTYSLDDISVVSSRRTRSSKDVDTTWHIDAYKFDLPFMNHPSDALASPEFVIEMGKQGGLGVINAE
GLWGRHADLDEAIAKVIAAYEEGDQAAATRTLQELHAAPLDTELLSERIAQVRDSGEIVAVRVSPQNVREIAPIVIKAGA
DLLVIQGTLISAEHVNTGGEALNLKEFIGSLDVPVIAGGVNDYTTALHMMRTGAVGIIVGGGENTNSLALGMEVSMATAI
ADVAAARRDYLDETGGRYVHIIADGSIENSGDVVKAIACGADAVVLGSPLARAEEAAGKGYFWPAVAAHPRFPRGVVTES
VDLDEAAPSLEQILHGPSTMPWGVENFEGGLKRALAKCGYTDLKSFQKVSLHVN

Specific function: Unknown

COG id: COG0516

COG function: function code F; IMP dehydrogenase/GMP reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IMPDH/GMPR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001093
- InterPro:   IPR005992 [H]

Pfam domain/function: PF00478 IMPDH [H]

EC number: 1.1.1.205

Molecular weight: Translated: 39771; Mature: 39771

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDHVEIGIGREARRTYSLDDISVVSSRRTRSSKDVDTTWHIDAYKFDLPFMNHPSDALA
CCCCEEECCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHC
SPEFVIEMGKQGGLGVINAEGLWGRHADLDEAIAKVIAAYEEGDQAAATRTLQELHAAPL
CCHHHEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
DTELLSERIAQVRDSGEIVAVRVSPQNVREIAPIVIKAGADLLVIQGTLISAEHVNTGGE
CHHHHHHHHHHHCCCCCEEEEEECCHHHHHHCCEEEECCCCEEEEECEEEEHHCCCCCCC
ALNLKEFIGSLDVPVIAGGVNDYTTALHMMRTGAVGIIVGGGENTNSLALGMEVSMATAI
EEEHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHH
ADVAAARRDYLDETGGRYVHIIADGSIENSGDVVKAIACGADAVVLGSPLARAEEAAGKG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHCCCC
YFWPAVAAHPRFPRGVVTESVDLDEAAPSLEQILHGPSTMPWGVENFEGGLKRALAKCGY
CCCCHHCCCCCCCCCCCCCCCCCHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
TDLKSFQKVSLHVN
HHHHCCEEEEEEEC
>Mature Secondary Structure
MRDHVEIGIGREARRTYSLDDISVVSSRRTRSSKDVDTTWHIDAYKFDLPFMNHPSDALA
CCCCEEECCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHC
SPEFVIEMGKQGGLGVINAEGLWGRHADLDEAIAKVIAAYEEGDQAAATRTLQELHAAPL
CCHHHEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
DTELLSERIAQVRDSGEIVAVRVSPQNVREIAPIVIKAGADLLVIQGTLISAEHVNTGGE
CHHHHHHHHHHHCCCCCEEEEEECCHHHHHHCCEEEECCCCEEEEECEEEEHHCCCCCCC
ALNLKEFIGSLDVPVIAGGVNDYTTALHMMRTGAVGIIVGGGENTNSLALGMEVSMATAI
EEEHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHH
ADVAAARRDYLDETGGRYVHIIADGSIENSGDVVKAIACGADAVVLGSPLARAEEAAGKG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHCCCC
YFWPAVAAHPRFPRGVVTESVDLDEAAPSLEQILHGPSTMPWGVENFEGGLKRALAKCGY
CCCCHHCCCCCCCCCCCCCCCCCHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
TDLKSFQKVSLHVN
HHHHCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: inosine 5'-phosphate; NAD+; H2O

Specific reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA