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The map label for this gene is tyrP [C]

Identifier: 62389379

GI number: 62389379

Start: 504324

End: 505571

Strand: Direct

Name: tyrP [C]

Synonym: cg0568

Alternate gene names: 62389379

Gene position: 504324-505571 (Clockwise)

Preceding gene: 62389378

Following gene: 62389380

Centisome position: 15.36

GC content: 55.93

Gene sequence:

>1248_bases
ATGACTACCGAATCAATAGTTGCGCACAATGCTGCAGGTACAGCACCTCAGAATGTGTCCTCTGCTAAGAAGAAGTACCT
CAGCGTTGCCCAAGGCGTTGCCCTTATCTACGGAACCAACATCGGCGCCGGTGTGCTCAGCCTCCCATACGCTGCCCGCA
ACGGTGGTTTCCTCGCCCTGGTTGTTGCCCTGCTCATTGCGGGAACACTGACCACCATCTCCATGCTCTACATCGCCGAA
GTATCCCTGCGCACCAAGAAGCCACTGCAGCTTTCCGGCCTGGCAGAAAAATACCTGGGGCAGTGGGGCCGCTGGCTGGT
GTTCATTGCCATTGTGGTCAACAGCGTGGGTGCACTGATTGCCTACGCATCAGGATCCGGCATTTTGATAGGCAACCTCA
CCGGCCTGCCACCAATCGTGGGCACCCTTGGATTCTTTGTTTTAGGCACCTTGATCATGTGGAAAGGCCTGCACACGGCA
AGCTTCGTGGAGGCATTGATCACCACTGGCATGGCAACGATCATCATCGTGCTGTGTGGATGGACAGTGCTTGGCCCTGG
AATTTCCGCAGACAACCTGATCGTGTTCCACCCATTCTTCATCGTTCCGATCATGAACCTCGCGGTCTTTACCTTCCTTG
CCCAATATGTGGTTCCAGAAATCGCACGAGGAGTTAACCCTGCCACCCCGAAGGCAGTGCCACGCGCGATCATCATCGGC
ATGGTCGCAACTGGTGTCACCCTGGCAGCTGTACCATTCGCGGCACTAGGGCTTCTGGGCACAGGCGTCAGTGAAGTTGT
CACCATCTCCTGGGGCGAAGCACTCGCCCCAGTGGCCTATTACATGGCCAATGCCTTCGCACTATTGGCCATGTTCACTT
CATTCATCGCCATTGGATTCACCGCGATGCGCAACGTACTAGATATTGGCCACTGGCCACAACACGGATGGCAGCGATCC
GTTGCTGTCGGACTAACTGTTCTTCCACCACTGGCAATTTCACTTGCGGGATTAGGCGGATTCGTGGCAGCACTGAGCTA
CGCCGGAGGATTTGCCGGAGCAATCATGTCCATCATCCCCGTGCTGTTGCTGCGCAACTCCCGCAAGAGTGGTGACCAAG
AACCAGTGTGGAAAGCCACCTGGCAAGCGCACCCCATCTTCCAGATCCTGTTGATTGTGGTGTACTCCCTGGCGTTTGTG
TACTCGGTTCTCGCGATCGTCGGATTAATGCCTGCGGGTTGGGCATAG

Upstream 100 bases:

>100_bases
GAGAAGGCGGAACCGAAGGAATCGAAGAATATCTCTCCGTGCGTTACCTCGCTTTGCCGTGACACATGAGCTGTCCGGTG
AATAACCCGAAGGAAAAAAC

Downstream 100 bases:

>100_bases
TCACTTCCTGTTGTGGCTGCCTGTTGCAGCCAAATACGGCCAACGGCTCCTTGGAAATTTAAGGGGTCGTTGGCCTTATT
ATTTTAGGGAAAGCCCATCC

Product: permease for amino acids and related compounds, fa

Products: Proton [Cytoplasm]; L-tyrosine [Cytoplasm] [C]

Alternate protein names: Amino Acid Permease; Tryptophan/Tyrosine Permease Family; Sodium-Coupled Neutral Amino Acid Transporter; Tryptophan/Tyrosine Permease; Amino Acid Transporter Transmembrane; Transmembrane Amino Acid Transporter Tyrosine-Specific; Tyrosine-Specific Transporter

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTTESIVAHNAAGTAPQNVSSAKKKYLSVAQGVALIYGTNIGAGVLSLPYAARNGGFLALVVALLIAGTLTTISMLYIAE
VSLRTKKPLQLSGLAEKYLGQWGRWLVFIAIVVNSVGALIAYASGSGILIGNLTGLPPIVGTLGFFVLGTLIMWKGLHTA
SFVEALITTGMATIIIVLCGWTVLGPGISADNLIVFHPFFIVPIMNLAVFTFLAQYVVPEIARGVNPATPKAVPRAIIIG
MVATGVTLAAVPFAALGLLGTGVSEVVTISWGEALAPVAYYMANAFALLAMFTSFIAIGFTAMRNVLDIGHWPQHGWQRS
VAVGLTVLPPLAISLAGLGGFVAALSYAGGFAGAIMSIIPVLLLRNSRKSGDQEPVWKATWQAHPIFQILLIVVYSLAFV
YSVLAIVGLMPAGWA

Sequences:

>Translated_415_residues
MTTESIVAHNAAGTAPQNVSSAKKKYLSVAQGVALIYGTNIGAGVLSLPYAARNGGFLALVVALLIAGTLTTISMLYIAE
VSLRTKKPLQLSGLAEKYLGQWGRWLVFIAIVVNSVGALIAYASGSGILIGNLTGLPPIVGTLGFFVLGTLIMWKGLHTA
SFVEALITTGMATIIIVLCGWTVLGPGISADNLIVFHPFFIVPIMNLAVFTFLAQYVVPEIARGVNPATPKAVPRAIIIG
MVATGVTLAAVPFAALGLLGTGVSEVVTISWGEALAPVAYYMANAFALLAMFTSFIAIGFTAMRNVLDIGHWPQHGWQRS
VAVGLTVLPPLAISLAGLGGFVAALSYAGGFAGAIMSIIPVLLLRNSRKSGDQEPVWKATWQAHPIFQILLIVVYSLAFV
YSVLAIVGLMPAGWA
>Mature_414_residues
TTESIVAHNAAGTAPQNVSSAKKKYLSVAQGVALIYGTNIGAGVLSLPYAARNGGFLALVVALLIAGTLTTISMLYIAEV
SLRTKKPLQLSGLAEKYLGQWGRWLVFIAIVVNSVGALIAYASGSGILIGNLTGLPPIVGTLGFFVLGTLIMWKGLHTAS
FVEALITTGMATIIIVLCGWTVLGPGISADNLIVFHPFFIVPIMNLAVFTFLAQYVVPEIARGVNPATPKAVPRAIIIGM
VATGVTLAAVPFAALGLLGTGVSEVVTISWGEALAPVAYYMANAFALLAMFTSFIAIGFTAMRNVLDIGHWPQHGWQRSV
AVGLTVLPPLAISLAGLGGFVAALSYAGGFAGAIMSIIPVLLLRNSRKSGDQEPVWKATWQAHPIFQILLIVVYSLAFVY
SVLAIVGLMPAGWA

Specific function: Involved In Transporting Tyrosine Across The Cytoplasmic Membrane. [C]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788218, Length=371, Percent_Identity=29.1105121293801, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 43374; Mature: 43243

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTESIVAHNAAGTAPQNVSSAKKKYLSVAQGVALIYGTNIGAGVLSLPYAARNGGFLAL
CCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHEEEECCCCCHHHHCCCCCCCCCHHHH
VVALLIAGTLTTISMLYIAEVSLRTKKPLQLSGLAEKYLGQWGRWLVFIAIVVNSVGALI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYASGSGILIGNLTGLPPIVGTLGFFVLGTLIMWKGLHTASFVEALITTGMATIIIVLCG
EEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
WTVLGPGISADNLIVFHPFFIVPIMNLAVFTFLAQYVVPEIARGVNPATPKAVPRAIIIG
HHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MVATGVTLAAVPFAALGLLGTGVSEVVTISWGEALAPVAYYMANAFALLAMFTSFIAIGF
HHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAMRNVLDIGHWPQHGWQRSVAVGLTVLPPLAISLAGLGGFVAALSYAGGFAGAIMSIIP
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VLLLRNSRKSGDQEPVWKATWQAHPIFQILLIVVYSLAFVYSVLAIVGLMPAGWA
HHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTESIVAHNAAGTAPQNVSSAKKKYLSVAQGVALIYGTNIGAGVLSLPYAARNGGFLAL
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHEEEECCCCCHHHHCCCCCCCCCHHHH
VVALLIAGTLTTISMLYIAEVSLRTKKPLQLSGLAEKYLGQWGRWLVFIAIVVNSVGALI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYASGSGILIGNLTGLPPIVGTLGFFVLGTLIMWKGLHTASFVEALITTGMATIIIVLCG
EEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
WTVLGPGISADNLIVFHPFFIVPIMNLAVFTFLAQYVVPEIARGVNPATPKAVPRAIIIG
HHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MVATGVTLAAVPFAALGLLGTGVSEVVTISWGEALAPVAYYMANAFALLAMFTSFIAIGF
HHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAMRNVLDIGHWPQHGWQRSVAVGLTVLPPLAISLAGLGGFVAALSYAGGFAGAIMSIIP
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VLLLRNSRKSGDQEPVWKATWQAHPIFQILLIVVYSLAFVYSVLAIVGLMPAGWA
HHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-tyrosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA