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The map label for this gene is xylB [H]

Identifier: 62389007

GI number: 62389007

Start: 124972

End: 126354

Strand: Direct

Name: xylB [H]

Synonym: cg0147

Alternate gene names: 62389007

Gene position: 124972-126354 (Clockwise)

Preceding gene: 62389006

Following gene: 62389012

Centisome position: 3.81

GC content: 59.15

Gene sequence:

>1383_bases
ATGGCTTTGGTTCTTGGAATCGATAGTTCCACCCAATCCTGCAAGGCTTTGCTTGTCGACGCCGCCACCGGCCAGGTTAT
CGACGAAGGCCGCGCGAGTCACCCGAGCGGGTCGGAGGTAGATCCACGTGCGTGGATCGCTGCGCTGGATCAAGCTACCG
AGGGGTTGTTAGAACGCGCGGACGCTGTATCTATTGCAGGCCAGCAGCACGGCATGGTGGCGTTGGATGAAAACGATGAA
ATCGTTCGCCCGGCGTTGTTATGGAATGACACTCGTTCTGCCCAGGCTGCGTTGGATCTCAATGAGGAGATCGGCGGCGA
TCAGGCTGCGGTAGATGCCACGGGAAGTGTGTATGTTGCTTCTTTAACTGCCACCAAAATGCGGTGGATGCGTGATCATG
AACCAGAAAATGCAGCGCGCACGGCGTCGGTGATGTTGCCTCATGATTTCCTCACCTGGCATTTGATGGGACGCGGACGC
AAAGTCACCGACCATGGTGATGCTTCTGGAACGGGCTACTACAGCACGCGTGATCGTGCGTGGCGCACCGATCTAGCTGC
CTTGGCGCTGGGCCATGAGGTGGAACTTCCTGAACTCCTGGCCCCAAATGCGATTGCGGGAACAACTCCAGGTGGAGTGA
AAGTTGCTGCAGGCACGGGAGATAATGCTGCGGCTGCGCTTGGCCTTGATTTGCAGCCTGGTGATGTCAGCGTGTCGATC
GGCACCTCTGGCGTTGCCGGCATGACCGTTCAACATAGCGTCCACGATCCATCTGGTTTGGTCACTGGTTTCGCCGATGC
CACGGGTGCGTATTTCCCGCTGGCCTGCACGCTTAATGGCGCACCGGTGTTGGAATTCGGCCGCCGCATTCTGGGCGTGG
AATGGGAAGAGTTCGATGCGCTTGCACTGGCTGCTCAACCCGGTTCAGGTGGCGTGACGCTCCAGCCTTATTTGGAGGGC
GAGCGTACGCCGAATCGTCCCGCAGCACGTGGCGTTTTGGCTGGACTAAACTGTGCAACGACCCGCGAGGACTTTGCCCG
AGCAACTGTTGAAGGCTTGTTGTTGGCATTGGATGATGCTGTAACGGCGCTGGTTGAGGCCACGGGAGTGCCCGTTCAGC
GCATCCAGCTCATCGGTGGCGGCGCGCGTTCACAGGCGGTTCGTGAGATTGCCCCTGAGATTTTCGGCCATGAGATTGTG
GTTCCAGAACCCGCTGAATATGTGGCGTTGGGTGCAGCTCGTCAGGCGGCATGGGCGCTGTCGGGTGAGGCCACGCCACC
GCAGTGGCCAACTCCCGGTTCCGATCCGCACCGCGCACCTAAAAACACTGAGCTGAGCACGCGTTATGCGAAGCTGCGTG
CTGCAACGCAGGGTTGGTACTAG

Upstream 100 bases:

>100_bases
GAGCAGCGGGATCTTTTGCGTAATTCGCGCGCGCAGATCCATGTGATTGACCACAATGGTGATGAAATTTTGGATACCCC
AACGGAAGAGGATTTTTAAG

Downstream 100 bases:

>100_bases
AGCTCGATATTGTCGATCAACCGCACCGGCCCCACGAAAATCGCGCCGACCACCAACGCTGGTTGGGTGAGCAGGCCGTC
GATTTCTAATGGTTCGAGGG

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERADAVSIAGQQHGMVALDENDE
IVRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVASLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGR
KVTDHGDASGTGYYSTRDRAWRTDLAALALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSI
GTSGVAGMTVQHSVHDPSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDALALAAQPGSGGVTLQPYLEG
ERTPNRPAARGVLAGLNCATTREDFARATVEGLLLALDDAVTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIV
VPEPAEYVALGAARQAAWALSGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY

Sequences:

>Translated_460_residues
MALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERADAVSIAGQQHGMVALDENDE
IVRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVASLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGR
KVTDHGDASGTGYYSTRDRAWRTDLAALALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSI
GTSGVAGMTVQHSVHDPSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDALALAAQPGSGGVTLQPYLEG
ERTPNRPAARGVLAGLNCATTREDFARATVEGLLLALDDAVTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIV
VPEPAEYVALGAARQAAWALSGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY
>Mature_459_residues
ALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERADAVSIAGQQHGMVALDENDEI
VRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVASLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGRK
VTDHGDASGTGYYSTRDRAWRTDLAALALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSIG
TSGVAGMTVQHSVHDPSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDALALAAQPGSGGVTLQPYLEGE
RTPNRPAARGVLAGLNCATTREDFARATVEGLLLALDDAVTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIVV
PEPAEYVALGAARQAAWALSGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=443, Percent_Identity=23.7020316027088, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4504007, Length=443, Percent_Identity=23.9277652370203, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI189409120, Length=443, Percent_Identity=23.9277652370203, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI42794763, Length=449, Percent_Identity=23.6080178173719, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI18860918, Length=488, Percent_Identity=23.7704918032787, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1789987, Length=490, Percent_Identity=31.8367346938775, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1790361, Length=497, Percent_Identity=24.9496981891348, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790005, Length=380, Percent_Identity=22.8947368421053, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554530, Length=476, Percent_Identity=23.3193277310924, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=447, Percent_Identity=25.9507829977629, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321633, Length=357, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356607, Length=494, Percent_Identity=24.8987854251012, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920476, Length=432, Percent_Identity=23.6111111111111, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 48061; Mature: 47930

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERA
CEEEEECCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DAVSIAGQQHGMVALDENDEIVRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVA
HHHEECCCCCCEEEECCCCCEECCEEEECCCCCCCEEECCHHHCCCCCEEEECCCCEEEE
SLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGRKVTDHGDASGTGYYSTRDRA
EHHHHHHHHHHCCCCCCHHHEEEEEECCHHEEEEEECCCCEECCCCCCCCCCCCCCCCCH
WRTDLAALALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSI
HHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEE
GTSGVAGMTVQHSVHDPSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDA
CCCCCCCEEEEECCCCCCCCEEECCCCCCCEEEEEEEECCCHHHHHCHHHHCCCHHHCCE
LALAAQPGSGGVTLQPYLEGERTPNRPAARGVLAGLNCATTREDFARATVEGLLLALDDA
EEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIVVPEPAEYVALGAARQAAWAL
HHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHCCHHHHHEEE
SGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERA
EEEEECCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DAVSIAGQQHGMVALDENDEIVRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVA
HHHEECCCCCCEEEECCCCCEECCEEEECCCCCCCEEECCHHHCCCCCEEEECCCCEEEE
SLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGRKVTDHGDASGTGYYSTRDRA
EHHHHHHHHHHCCCCCCHHHEEEEEECCHHEEEEEECCCCEECCCCCCCCCCCCCCCCCH
WRTDLAALALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSI
HHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEE
GTSGVAGMTVQHSVHDPSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDA
CCCCCCCEEEEECCCCCCCCEEECCCCCCCEEEEEEEECCCHHHHHCHHHHCCCHHHCCE
LALAAQPGSGGVTLQPYLEGERTPNRPAARGVLAGLNCATTREDFARATVEGLLLALDDA
EEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIVVPEPAEYVALGAARQAAWAL
HHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHCCHHHHHEEE
SGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]