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The map label for this gene is glpR [H]

Identifier: 62389006

GI number: 62389006

Start: 124122

End: 124970

Strand: Direct

Name: glpR [H]

Synonym: cg0146

Alternate gene names: 62389006

Gene position: 124122-124970 (Clockwise)

Preceding gene: 62389002

Following gene: 62389007

Centisome position: 3.78

GC content: 52.77

Gene sequence:

>849_bases
ATGTCCCAAGTGATTCCCGCCAGCTCACAAGAAAAGCGTCGTGAGCGCATCGTTTCTTATGTCACCCGTCATGGATTCGC
TCGTGTTGAAGCATTAGCTGAGCTTTTTGAGGTCAGCGCAATGACCATTCACCGTGATTTGGAGGCGCTGGCTGCAGACA
ATTTGGTGGAGCGCATTAGGGGTGGCGCGCGTTCGGTGTCGCCGTCGATGAGTGAGTTGGCAGTGGAGCAGCGTCGGCAT
TTGCATCGCACTGTTAAAGAGGCGTTGTGTACTGCAGCAGCACGGTTGATTCCGGAGGGCGCTGTGGTGGCGATTGATGA
TTCCACCACGTTGGAGTCTTTGGTTGAGAAGTTGCCGCAGCGGTCACCATCGGCGTTGATTACGCATTCTTTGAAGACAA
TGGCGGATCATCGTGTGCGCGCCGGGATGAGCGATATCCGTTTGATTGCGTGTGCGGGATTGTATTTCGCGGAGACTGAT
TCTTTCTTGGGCAAGGCAACTTCAGCGCAGTTGAATGAGCTGTCGGCGGATATTTCTTTTGTTTCTACGACTGCGGTGCG
CGCTACGGGGGAGGTTCCGGCGCTGTTTCATCCTGATATGGAGGCTGCTGATACGAAGCGGGCGTTGATTGGGATTGGTA
GCGTGCGTGTGTTGGTGGTGGATTCTAGTAAATTTGGTTCGGCTGGTGTGTTCAAGGTTGCTTCGATTGAGGAGTTTGAC
CACATCATCATTGATCAGCAGTGCACCCGTGAGCAGCGGGATCTTTTGCGTAATTCGCGCGCGCAGATCCATGTGATTGA
CCACAATGGTGATGAAATTTTGGATACCCCAACGGAAGAGGATTTTTAA

Upstream 100 bases:

>100_bases
AACAACAATCTAACGCCATCATGTTATAAAAAAGCAAGACCTAACATAAAAATGTTAGAAAGTGCTGGATCTAACAACAT
TTCCGTGGTAACTTTTTCAC

Downstream 100 bases:

>100_bases
GATGGCTTTGGTTCTTGGAATCGATAGTTCCACCCAATCCTGCAAGGCTTTGCTTGTCGACGCCGCCACCGGCCAGGTTA
TCGACGAAGGCCGCGCGAGT

Product: DeoR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSQVIPASSQEKRRERIVSYVTRHGFARVEALAELFEVSAMTIHRDLEALAADNLVERIRGGARSVSPSMSELAVEQRRH
LHRTVKEALCTAAARLIPEGAVVAIDDSTTLESLVEKLPQRSPSALITHSLKTMADHRVRAGMSDIRLIACAGLYFAETD
SFLGKATSAQLNELSADISFVSTTAVRATGEVPALFHPDMEAADTKRALIGIGSVRVLVVDSSKFGSAGVFKVASIEEFD
HIIIDQQCTREQRDLLRNSRAQIHVIDHNGDEILDTPTEEDF

Sequences:

>Translated_282_residues
MSQVIPASSQEKRRERIVSYVTRHGFARVEALAELFEVSAMTIHRDLEALAADNLVERIRGGARSVSPSMSELAVEQRRH
LHRTVKEALCTAAARLIPEGAVVAIDDSTTLESLVEKLPQRSPSALITHSLKTMADHRVRAGMSDIRLIACAGLYFAETD
SFLGKATSAQLNELSADISFVSTTAVRATGEVPALFHPDMEAADTKRALIGIGSVRVLVVDSSKFGSAGVFKVASIEEFD
HIIIDQQCTREQRDLLRNSRAQIHVIDHNGDEILDTPTEEDF
>Mature_281_residues
SQVIPASSQEKRRERIVSYVTRHGFARVEALAELFEVSAMTIHRDLEALAADNLVERIRGGARSVSPSMSELAVEQRRHL
HRTVKEALCTAAARLIPEGAVVAIDDSTTLESLVEKLPQRSPSALITHSLKTMADHRVRAGMSDIRLIACAGLYFAETDS
FLGKATSAQLNELSADISFVSTTAVRATGEVPALFHPDMEAADTKRALIGIGSVRVLVVDSSKFGSAGVFKVASIEEFDH
IIIDQQCTREQRDLLRNSRAQIHVIDHNGDEILDTPTEEDF

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=236, Percent_Identity=30.0847457627119, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=23.3201581027668, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789170, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789519, Length=258, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789059, Length=238, Percent_Identity=24.7899159663866, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787540, Length=256, Percent_Identity=24.21875, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 30886; Mature: 30755

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVIPASSQEKRRERIVSYVTRHGFARVEALAELFEVSAMTIHRDLEALAADNLVERIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGARSVSPSMSELAVEQRRHLHRTVKEALCTAAARLIPEGAVVAIDDSTTLESLVEKLPQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCC
RSPSALITHSLKTMADHRVRAGMSDIRLIACAGLYFAETDSFLGKATSAQLNELSADISF
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSTTAVRATGEVPALFHPDMEAADTKRALIGIGSVRVLVVDSSKFGSAGVFKVASIEEFD
HHHHHHHCCCCCCEEECCCCCHHHHHHHHEEECCEEEEEEECCCCCCCCEEEEECHHHHH
HIIIDQQCTREQRDLLRNSRAQIHVIDHNGDEILDTPTEEDF
HHHHCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQVIPASSQEKRRERIVSYVTRHGFARVEALAELFEVSAMTIHRDLEALAADNLVERIR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGARSVSPSMSELAVEQRRHLHRTVKEALCTAAARLIPEGAVVAIDDSTTLESLVEKLPQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCC
RSPSALITHSLKTMADHRVRAGMSDIRLIACAGLYFAETDSFLGKATSAQLNELSADISF
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSTTAVRATGEVPALFHPDMEAADTKRALIGIGSVRVLVVDSSKFGSAGVFKVASIEEFD
HHHHHHHCCCCCCEEECCCCCHHHHHHHHEEECCEEEEEEECCCCCCCCEEEEECHHHHH
HIIIDQQCTREQRDLLRNSRAQIHVIDHNGDEILDTPTEEDF
HHHHCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]