Click here to switch to the map view.

The map label for this gene is putA [H]

Identifier: 62388994

GI number: 62388994

Start: 107436

End: 110894

Strand: Direct

Name: putA [H]

Synonym: cg0129

Alternate gene names: 62388994

Gene position: 107436-110894 (Clockwise)

Preceding gene: 62388990

Following gene: 62388995

Centisome position: 3.27

GC content: 58.28

Gene sequence:

>3459_bases
ATGACGTCGATGAATCTGCCTATTGAGTTGGCTACGCTGTCTGACCAGGCTGTGGACAAGGTGCGCTCCTGGCTGGAGTA
CAGCAAAAAGGAAAGCGTGCCCAATGCCGATGCGAAGCGTCTAGCTGCAGTGTTGCAGGATCCTAATGGTTTGGAATTCA
CGGTTGGTTTCGTGGATCGAGTGGTTCGAACTGAGGATCGTGAAGCGGCAGCGCATGCGTTGTATGAGTTGGGCAAGATT
GCTCCGTCGACGATGTCCTTTTTGGATCGGGCGCAGATTCAGGCCGGTTCTTTGGTGGGGCGGGCGTTGCCGCAGGTTGT
GGTTCCTGCGGCGCGGGCTCGAATCCGGCAGATGGTTGGGCACATGATTGTGGATGCCCGCGACAAGCAGTTCGCCAAGG
CTGTCGCTGAGATTCAGTCGGATGGGCACCGCCTGAACATCAATTTGCTAGGTGAAGCGGTGTTGGGCCGAAAGGAGGCA
GCGAAGCATTTGGATGACACGGTGCGGTTGTTGCGCCGTCCGGATGTGGAATATGTGTCCATCAAGGTCTCTTCGGTGGC
ATCGCAGATTTCGATGTGGGGTTTCGAAGACACCGTTAATTATGTTGTGGAACAGCTGACACCTTTATATATAGAGGCCG
CGCGGGCGCCGAAAGGCACGAAGTTCATCAACCTGGACATGGAGGAATACCGCGATCTGCGCCTGACTATGGAGGTGTTC
AAGCGGCTGCTCTCCAATCCAGAGCTGCATGAACTAGAAGCCGGAATTGTGTTGCAGGCGTACCTTCCCGATGCCCTCGG
TGCAATCCAGGACTTGGCGCAGTTCGGCCGCGAGCGCGTCAACACAGGCGGGGCGGGCGTTAAGGTTCGCCTGGTCAAGG
GTGCTAATTTGCCTATGGAGCACGTCCACGCGCAGATCACCGGCTGGCCAGTTGCCACAGAACCTTCCAAACAAGCCACC
GATGCCAATTACAAGCGCGTCCTCTATTGGACGATGCGCAAAGAAAACATGGAGGGCCTGCGCCTGGGCGTTGCCGGCCA
CAACCTTTTCGACATAGCATTCGCACATTTGCTCTCTGTGGAGCGTGGGGTAGCGGACCGTGTGGAGTTCGAAATGCTGC
AGGGCATGGCGTCCGATCAGGCGCGCGCCGTCAGCGTTGACGTCGGTGAGCTGCTGCTTTACGTACCAGCCGTGCGCCCA
CAAGAATTCGACGTGGCCATTTCTTACCTCGTGCGCCGCCTCGAGGAAAACGCCGCGAGCGAAAACTTCATGTCCGCCAT
CTTCGACCTCGACGCCGACAACCCGTCCTTCAAGCGAGAGGAGAGCCGCTTCCGCGCCTCCATATCTGACCTCGCCACGC
TCATCGACGTGCCCGCGCCCGGCCCCAACCACACACAAGACCGCAGCAAAGAGACGCTTCTCGACGCCCCCCTCGTCCCA
TTTATCAACGAGCCCGACACCAACCCAGCGCTCATCCAAAACCAACAGTGGGCCACAAAAGCCGTCGCCACCGCAGCAGA
GCCCGGTTGGTTGGAAAAACAAACAAAGCCGGAGGTGTTGGAAGAGGGGGACGTCGACAAGCTAATTAACGATGTGCGCG
ACGCTGCTGAAGCGTGGGCAGCGCGCCCAGCCCGTGAACGCGCTGAGATTTTGTACAAGACCGCCGAGATTTTGCGCGTG
CGACGCGGACACCTGATCTCAGTGACGGCCGCGGAGGTGGGCAAAGCTGTGGAACAAACCGACCCGGAAATCTCTGAAGC
CATTGATTTCGCCCGCTACTACGCGCATTTGGCCCTGGAATTGGACGACGTAGACAATGCGGAATTCACCCCAGATCGCG
TCGTTGTGGTGACCCCGCCCTGGAATTTCCCCATCGCGATCCCCGCTGGATCGACTTTCGCAGCACTCGCGGCGGGCGCT
GGCGTGATCCACAAACCCTCAAAGCCTAGCCAACATTGCTCCGCTGCAGTGGTCGAAGCCCTCTGGGAAGCCGGCGTTCC
CCGCGAGGTTCTGCATTGCATTTACCCAGCTAATCGCGATGTTGGATGTGCGTTGATCAGCCATGAACACGTCGACCGCG
TCATTTTGACCGGCTCCTCCGAGACCGCCGCGATGTTCTCCTCCTGGCGACCAGAACTCACCATCAACGGCGAAACCTCC
GGCAAAAACGCCATCGTGGTCACCCCATCTGCCGACCGCGACCTCGCCGTCGCCGACCTGGTGAAATCCGCCTTCGGCCA
TGCAGGACAAAAATGTTCCGCAGCCTCCCTCGGCATCTTGGTAGGCAGCGTCTACGAATCAGAACGCTTCCGGAAACAGC
TGGTAGACGCCGCATCCTCACTCATCGTCGACTGGCCTACCAACCCCTCCGCAACCGTCGGACCACTCACCGAACTCCCC
AGCGATAAACTCCACCACGCCCTAACCACCCTCGAAGAAGGAGAAAGCTGGCTGCTGAAACCCCGACAACTCGACGACAC
CGGCCGACTCTGGTCACCCGGCATCAAAGAAGGCGTCAAACCAGGAACCTTCTTCCACCTCACAGAAGTATTCGGACCAG
TCCTCGGCCTGATGAAAGCCACCGACCTCAATGAAGCCATCGAATTCCAAAACGGCAACGACTTCGGACTCACCGGCGGA
CTCCAATCCCTCGACGCCGACGAAGTCCGCACCTGGCTTGACCACGTCGATGTCGGAAACGCCTACGTCAACCGCGGCAT
CACCGGCGCCATTGTCCAACGCCAATCCTTCGGAGGCTGGAAAAAATCCTCCGTCGGCCTCGGATCCAAAGCCGGAGGAC
CCAACTATGTCATGCTCATGGGAACCTGGGCCGACGCGCCAAGCCACCACGCCCCACGCGAAACAAACCCGCTGATCAGC
AAACTGGATCTCCCCGGAGAAGAGCTCGAATGGCTCGAAAAAGCCAACGCCAGCGATGAAACAGCATGGAACACGGAATT
CGGCAGCCCACGCGACCCCTCCGGCCTCGATGTAGAAGCCAACATTTTCCGCTACCGACCAGCAGAGGTAGTACTCCGAC
TCGACGATTCCGCCACACCCCGAGAAACTGCCCGCGCATTGTTGGCAGCCCGTCGCGCCGGGGTTACTCCGCGAGTTCTT
CAAACACCAGGTGTTTCAGAGCAAGTCCGCGAAGTATTGTCCGCTGCTGGAGTGAGTGCAGAAACAGTCGATGATTCGGT
ATTTATTTCCAACGTGTTGCGCGGCGAATACGACGAGAACTCCAGCGTCCGAGTCCGCTACCTGGGCAAAGTTAGCGACA
CTGTCCGTGAACGCCTATCTGTACGGCCCGAAGTTGTTCTGCTTGACGATGCAGTAACTGCCTCCGGTCGAGTTGAATTA
CGTTACTGGCTCAAAGAACAAGCAATTTCCATGACGTTGCACCGTTTTGGAAACCCAGTTGCGGCCTTCCACGAGTTGGC
GGAGGAACTTAAACGTTGA

Upstream 100 bases:

>100_bases
GGGATTATGTTGGGGGCCACATCTGAAAATAGTTGCTGGGATCCATCACACCTACGATGCGAAACGGCACCCACACCGCT
GATCTTGAAGGAGAACCACC

Downstream 100 bases:

>100_bases
TCGTTTTGCGCATGGGTCGCTGCGTGCCGATTTAAGGGCTTCGTCAGTCGCAGCGACCTGTTGTCCTGATTTCAGTTCTG
AAGGCTCTTAGAGGCGATTC

Product: proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1152; Mature: 1151

Protein sequence:

>1152_residues
MTSMNLPIELATLSDQAVDKVRSWLEYSKKESVPNADAKRLAAVLQDPNGLEFTVGFVDRVVRTEDREAAAHALYELGKI
APSTMSFLDRAQIQAGSLVGRALPQVVVPAARARIRQMVGHMIVDARDKQFAKAVAEIQSDGHRLNINLLGEAVLGRKEA
AKHLDDTVRLLRRPDVEYVSIKVSSVASQISMWGFEDTVNYVVEQLTPLYIEAARAPKGTKFINLDMEEYRDLRLTMEVF
KRLLSNPELHELEAGIVLQAYLPDALGAIQDLAQFGRERVNTGGAGVKVRLVKGANLPMEHVHAQITGWPVATEPSKQAT
DANYKRVLYWTMRKENMEGLRLGVAGHNLFDIAFAHLLSVERGVADRVEFEMLQGMASDQARAVSVDVGELLLYVPAVRP
QEFDVAISYLVRRLEENAASENFMSAIFDLDADNPSFKREESRFRASISDLATLIDVPAPGPNHTQDRSKETLLDAPLVP
FINEPDTNPALIQNQQWATKAVATAAEPGWLEKQTKPEVLEEGDVDKLINDVRDAAEAWAARPARERAEILYKTAEILRV
RRGHLISVTAAEVGKAVEQTDPEISEAIDFARYYAHLALELDDVDNAEFTPDRVVVVTPPWNFPIAIPAGSTFAALAAGA
GVIHKPSKPSQHCSAAVVEALWEAGVPREVLHCIYPANRDVGCALISHEHVDRVILTGSSETAAMFSSWRPELTINGETS
GKNAIVVTPSADRDLAVADLVKSAFGHAGQKCSAASLGILVGSVYESERFRKQLVDAASSLIVDWPTNPSATVGPLTELP
SDKLHHALTTLEEGESWLLKPRQLDDTGRLWSPGIKEGVKPGTFFHLTEVFGPVLGLMKATDLNEAIEFQNGNDFGLTGG
LQSLDADEVRTWLDHVDVGNAYVNRGITGAIVQRQSFGGWKKSSVGLGSKAGGPNYVMLMGTWADAPSHHAPRETNPLIS
KLDLPGEELEWLEKANASDETAWNTEFGSPRDPSGLDVEANIFRYRPAEVVLRLDDSATPRETARALLAARRAGVTPRVL
QTPGVSEQVREVLSAAGVSAETVDDSVFISNVLRGEYDENSSVRVRYLGKVSDTVRERLSVRPEVVLLDDAVTASGRVEL
RYWLKEQAISMTLHRFGNPVAAFHELAEELKR

Sequences:

>Translated_1152_residues
MTSMNLPIELATLSDQAVDKVRSWLEYSKKESVPNADAKRLAAVLQDPNGLEFTVGFVDRVVRTEDREAAAHALYELGKI
APSTMSFLDRAQIQAGSLVGRALPQVVVPAARARIRQMVGHMIVDARDKQFAKAVAEIQSDGHRLNINLLGEAVLGRKEA
AKHLDDTVRLLRRPDVEYVSIKVSSVASQISMWGFEDTVNYVVEQLTPLYIEAARAPKGTKFINLDMEEYRDLRLTMEVF
KRLLSNPELHELEAGIVLQAYLPDALGAIQDLAQFGRERVNTGGAGVKVRLVKGANLPMEHVHAQITGWPVATEPSKQAT
DANYKRVLYWTMRKENMEGLRLGVAGHNLFDIAFAHLLSVERGVADRVEFEMLQGMASDQARAVSVDVGELLLYVPAVRP
QEFDVAISYLVRRLEENAASENFMSAIFDLDADNPSFKREESRFRASISDLATLIDVPAPGPNHTQDRSKETLLDAPLVP
FINEPDTNPALIQNQQWATKAVATAAEPGWLEKQTKPEVLEEGDVDKLINDVRDAAEAWAARPARERAEILYKTAEILRV
RRGHLISVTAAEVGKAVEQTDPEISEAIDFARYYAHLALELDDVDNAEFTPDRVVVVTPPWNFPIAIPAGSTFAALAAGA
GVIHKPSKPSQHCSAAVVEALWEAGVPREVLHCIYPANRDVGCALISHEHVDRVILTGSSETAAMFSSWRPELTINGETS
GKNAIVVTPSADRDLAVADLVKSAFGHAGQKCSAASLGILVGSVYESERFRKQLVDAASSLIVDWPTNPSATVGPLTELP
SDKLHHALTTLEEGESWLLKPRQLDDTGRLWSPGIKEGVKPGTFFHLTEVFGPVLGLMKATDLNEAIEFQNGNDFGLTGG
LQSLDADEVRTWLDHVDVGNAYVNRGITGAIVQRQSFGGWKKSSVGLGSKAGGPNYVMLMGTWADAPSHHAPRETNPLIS
KLDLPGEELEWLEKANASDETAWNTEFGSPRDPSGLDVEANIFRYRPAEVVLRLDDSATPRETARALLAARRAGVTPRVL
QTPGVSEQVREVLSAAGVSAETVDDSVFISNVLRGEYDENSSVRVRYLGKVSDTVRERLSVRPEVVLLDDAVTASGRVEL
RYWLKEQAISMTLHRFGNPVAAFHELAEELKR
>Mature_1151_residues
TSMNLPIELATLSDQAVDKVRSWLEYSKKESVPNADAKRLAAVLQDPNGLEFTVGFVDRVVRTEDREAAAHALYELGKIA
PSTMSFLDRAQIQAGSLVGRALPQVVVPAARARIRQMVGHMIVDARDKQFAKAVAEIQSDGHRLNINLLGEAVLGRKEAA
KHLDDTVRLLRRPDVEYVSIKVSSVASQISMWGFEDTVNYVVEQLTPLYIEAARAPKGTKFINLDMEEYRDLRLTMEVFK
RLLSNPELHELEAGIVLQAYLPDALGAIQDLAQFGRERVNTGGAGVKVRLVKGANLPMEHVHAQITGWPVATEPSKQATD
ANYKRVLYWTMRKENMEGLRLGVAGHNLFDIAFAHLLSVERGVADRVEFEMLQGMASDQARAVSVDVGELLLYVPAVRPQ
EFDVAISYLVRRLEENAASENFMSAIFDLDADNPSFKREESRFRASISDLATLIDVPAPGPNHTQDRSKETLLDAPLVPF
INEPDTNPALIQNQQWATKAVATAAEPGWLEKQTKPEVLEEGDVDKLINDVRDAAEAWAARPARERAEILYKTAEILRVR
RGHLISVTAAEVGKAVEQTDPEISEAIDFARYYAHLALELDDVDNAEFTPDRVVVVTPPWNFPIAIPAGSTFAALAAGAG
VIHKPSKPSQHCSAAVVEALWEAGVPREVLHCIYPANRDVGCALISHEHVDRVILTGSSETAAMFSSWRPELTINGETSG
KNAIVVTPSADRDLAVADLVKSAFGHAGQKCSAASLGILVGSVYESERFRKQLVDAASSLIVDWPTNPSATVGPLTELPS
DKLHHALTTLEEGESWLLKPRQLDDTGRLWSPGIKEGVKPGTFFHLTEVFGPVLGLMKATDLNEAIEFQNGNDFGLTGGL
QSLDADEVRTWLDHVDVGNAYVNRGITGAIVQRQSFGGWKKSSVGLGSKAGGPNYVMLMGTWADAPSHHAPRETNPLISK
LDLPGEELEWLEKANASDETAWNTEFGSPRDPSGLDVEANIFRYRPAEVVLRLDDSATPRETARALLAARRAGVTPRVLQ
TPGVSEQVREVLSAAGVSAETVDDSVFISNVLRGEYDENSSVRVRYLGKVSDTVRERLSVRPEVVLLDDAVTASGRVELR
YWLKEQAISMTLHRFGNPVAAFHELAEELKR

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=436, Percent_Identity=28.4403669724771, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI25777736, Length=450, Percent_Identity=30, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI25777734, Length=450, Percent_Identity=30, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI238859541, Length=450, Percent_Identity=29.7777777777778, Blast_Score=127, Evalue=7e-29,
Organism=Homo sapiens, GI25777724, Length=496, Percent_Identity=25.6048387096774, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI11095441, Length=420, Percent_Identity=25.952380952381, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI25777730, Length=426, Percent_Identity=25.1173708920188, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI25777728, Length=400, Percent_Identity=26.75, Blast_Score=118, Evalue=3e-26,
Organism=Homo sapiens, GI153266822, Length=455, Percent_Identity=25.4945054945055, Blast_Score=117, Evalue=7e-26,
Organism=Homo sapiens, GI25777732, Length=488, Percent_Identity=25.8196721311475, Blast_Score=116, Evalue=1e-25,
Organism=Homo sapiens, GI12007648, Length=429, Percent_Identity=24.4755244755245, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI21614513, Length=413, Percent_Identity=23.2445520581114, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI115387104, Length=425, Percent_Identity=22.8235294117647, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI238814322, Length=416, Percent_Identity=23.0769230769231, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI25777726, Length=493, Percent_Identity=24.3407707910751, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI188035924, Length=464, Percent_Identity=25, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI310128103, Length=442, Percent_Identity=25.1131221719457, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI4507229, Length=421, Percent_Identity=26.3657957244656, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI310128093, Length=425, Percent_Identity=25.1764705882353, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI25777721, Length=434, Percent_Identity=25.5760368663594, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI25952152, Length=237, Percent_Identity=25.3164556962025, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI4502043, Length=412, Percent_Identity=24.0291262135922, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI238814371, Length=412, Percent_Identity=24.0291262135922, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI310128091, Length=377, Percent_Identity=24.6684350132626, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI71773324, Length=397, Percent_Identity=23.4256926952141, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI310128087, Length=250, Percent_Identity=26, Blast_Score=72, Evalue=4e-12,
Organism=Homo sapiens, GI73695881, Length=395, Percent_Identity=23.5443037974684, Blast_Score=68, Evalue=5e-11,
Organism=Homo sapiens, GI73695879, Length=395, Percent_Identity=23.5443037974684, Blast_Score=68, Evalue=5e-11,
Organism=Homo sapiens, GI301500698, Length=418, Percent_Identity=22.0095693779904, Blast_Score=68, Evalue=6e-11,
Organism=Escherichia coli, GI1787250, Length=817, Percent_Identity=29.4981640146879, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1788042, Length=423, Percent_Identity=29.5508274231678, Blast_Score=133, Evalue=6e-32,
Organism=Escherichia coli, GI87081926, Length=413, Percent_Identity=26.1501210653753, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87081896, Length=439, Percent_Identity=27.1070615034169, Blast_Score=124, Evalue=5e-29,
Organism=Escherichia coli, GI1789015, Length=424, Percent_Identity=28.3018867924528, Blast_Score=122, Evalue=2e-28,
Organism=Escherichia coli, GI1787684, Length=419, Percent_Identity=26.0143198090692, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1786504, Length=422, Percent_Identity=26.303317535545, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI1787558, Length=423, Percent_Identity=26.0047281323877, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI87082295, Length=430, Percent_Identity=24.6511627906977, Blast_Score=94, Evalue=6e-20,
Organism=Escherichia coli, GI1787715, Length=406, Percent_Identity=24.1379310344828, Blast_Score=90, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI25143874, Length=420, Percent_Identity=28.3333333333333, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25143876, Length=420, Percent_Identity=28.3333333333333, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI115534176, Length=430, Percent_Identity=27.6744186046512, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI133930964, Length=426, Percent_Identity=25.3521126760563, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71986308, Length=401, Percent_Identity=24.4389027431421, Blast_Score=113, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17534447, Length=449, Percent_Identity=27.8396436525612, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534119, Length=442, Percent_Identity=25.1131221719457, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17562198, Length=432, Percent_Identity=25.2314814814815, Blast_Score=106, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25144435, Length=412, Percent_Identity=25.2427184466019, Blast_Score=106, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI32564736, Length=398, Percent_Identity=25.1256281407035, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71995606, Length=427, Percent_Identity=24.3559718969555, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551164, Length=434, Percent_Identity=22.3502304147465, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32564151, Length=398, Percent_Identity=25.8793969849246, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995613, Length=384, Percent_Identity=25, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990744, Length=257, Percent_Identity=29.9610894941634, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17564084, Length=417, Percent_Identity=23.021582733813, Blast_Score=76, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321826, Length=497, Percent_Identity=29.5774647887324, Blast_Score=129, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323821, Length=507, Percent_Identity=25.4437869822485, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324950, Length=419, Percent_Identity=23.8663484486874, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323822, Length=450, Percent_Identity=24.6666666666667, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6320917, Length=441, Percent_Identity=25.6235827664399, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325196, Length=407, Percent_Identity=25.3071253071253, Blast_Score=101, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6319478, Length=435, Percent_Identity=24.367816091954, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281362580, Length=434, Percent_Identity=28.110599078341, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI62472918, Length=434, Percent_Identity=28.110599078341, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI62472926, Length=434, Percent_Identity=28.110599078341, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI62472936, Length=434, Percent_Identity=28.110599078341, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356737, Length=434, Percent_Identity=28.110599078341, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI20129399, Length=474, Percent_Identity=24.0506329113924, Blast_Score=117, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24668425, Length=549, Percent_Identity=25.8652094717668, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668417, Length=549, Percent_Identity=25.8652094717668, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668413, Length=549, Percent_Identity=25.8652094717668, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24650465, Length=437, Percent_Identity=25.1716247139588, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571798, Length=507, Percent_Identity=25.6410256410256, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571796, Length=507, Percent_Identity=25.6410256410256, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571794, Length=507, Percent_Identity=25.6410256410256, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571806, Length=507, Percent_Identity=25.6410256410256, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571802, Length=507, Percent_Identity=25.6410256410256, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571800, Length=507, Percent_Identity=25.6410256410256, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24666674, Length=491, Percent_Identity=25.050916496945, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24585660, Length=433, Percent_Identity=23.5565819861432, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24638876, Length=390, Percent_Identity=23.5897435897436, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24638878, Length=390, Percent_Identity=23.5897435897436, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574525, Length=444, Percent_Identity=23.4234234234234, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 126323; Mature: 126192

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSMNLPIELATLSDQAVDKVRSWLEYSKKESVPNADAKRLAAVLQDPNGLEFTVGFVDR
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEHHHHHH
VVRTEDREAAAHALYELGKIAPSTMSFLDRAQIQAGSLVGRALPQVVVPAARARIRQMVG
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HMIVDARDKQFAKAVAEIQSDGHRLNINLLGEAVLGRKEAAKHLDDTVRLLRRPDVEYVS
HHHHCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEE
IKVSSVASQISMWGFEDTVNYVVEQLTPLYIEAARAPKGTKFINLDMEEYRDLRLTMEVF
EEHHHHHHHHHHCCHHHHHHHHHHHCCHHHEECCCCCCCCEEEECCHHHHHHHHHHHHHH
KRLLSNPELHELEAGIVLQAYLPDALGAIQDLAQFGRERVNTGGAGVKVRLVKGANLPME
HHHHCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
HVHAQITGWPVATEPSKQATDANYKRVLYWTMRKENMEGLRLGVAGHNLFDIAFAHLLSV
HHHEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHH
ERGVADRVEFEMLQGMASDQARAVSVDVGELLLYVPAVRPQEFDVAISYLVRRLEENAAS
HHCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ENFMSAIFDLDADNPSFKREESRFRASISDLATLIDVPAPGPNHTQDRSKETLLDAPLVP
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCC
FINEPDTNPALIQNQQWATKAVATAAEPGWLEKQTKPEVLEEGDVDKLINDVRDAAEAWA
CCCCCCCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
ARPARERAEILYKTAEILRVRRGHLISVTAAEVGKAVEQTDPEISEAIDFARYYAHLALE
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEE
LDDVDNAEFTPDRVVVVTPPWNFPIAIPAGSTFAALAAGAGVIHKPSKPSQHCSAAVVEA
ECCCCCCCCCCCEEEEEECCCCCCEEECCCCHHHHHHCCCCCEECCCCCHHHHHHHHHHH
LWEAGVPREVLHCIYPANRDVGCALISHEHVDRVILTGSSETAAMFSSWRPELTINGETS
HHHCCCCHHHHHHHCCCCCCCCEEEECHHCCCEEEEECCCHHHHHHHCCCCCEEECCCCC
GKNAIVVTPSADRDLAVADLVKSAFGHAGQKCSAASLGILVGSVYESERFRKQLVDAASS
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVDWPTNPSATVGPLTELPSDKLHHALTTLEEGESWLLKPRQLDDTGRLWSPGIKEGVK
EEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCHHHCCC
PGTFFHLTEVFGPVLGLMKATDLNEAIEFQNGNDFGLTGGLQSLDADEVRTWLDHVDVGN
CCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCH
AYVNRGITGAIVQRQSFGGWKKSSVGLGSKAGGPNYVMLMGTWADAPSHHAPRETNPLIS
HHHHCCCCCHHEEHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHH
KLDLPGEELEWLEKANASDETAWNTEFGSPRDPSGLDVEANIFRYRPAEVVLRLDDSATP
HCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCEEEECCHHEEEEECCCCCH
RETARALLAARRAGVTPRVLQTPGVSEQVREVLSAAGVSAETVDDSVFISNVLRGEYDEN
HHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCCCC
SSVRVRYLGKVSDTVRERLSVRPEVVLLDDAVTASGRVELRYWLKEQAISMTLHRFGNPV
CCEEEEEECHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCHH
AAFHELAEELKR
HHHHHHHHHHCC
>Mature Secondary Structure 
TSMNLPIELATLSDQAVDKVRSWLEYSKKESVPNADAKRLAAVLQDPNGLEFTVGFVDR
CCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEHHHHHH
VVRTEDREAAAHALYELGKIAPSTMSFLDRAQIQAGSLVGRALPQVVVPAARARIRQMVG
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HMIVDARDKQFAKAVAEIQSDGHRLNINLLGEAVLGRKEAAKHLDDTVRLLRRPDVEYVS
HHHHCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEE
IKVSSVASQISMWGFEDTVNYVVEQLTPLYIEAARAPKGTKFINLDMEEYRDLRLTMEVF
EEHHHHHHHHHHCCHHHHHHHHHHHCCHHHEECCCCCCCCEEEECCHHHHHHHHHHHHHH
KRLLSNPELHELEAGIVLQAYLPDALGAIQDLAQFGRERVNTGGAGVKVRLVKGANLPME
HHHHCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
HVHAQITGWPVATEPSKQATDANYKRVLYWTMRKENMEGLRLGVAGHNLFDIAFAHLLSV
HHHEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHH
ERGVADRVEFEMLQGMASDQARAVSVDVGELLLYVPAVRPQEFDVAISYLVRRLEENAAS
HHCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ENFMSAIFDLDADNPSFKREESRFRASISDLATLIDVPAPGPNHTQDRSKETLLDAPLVP
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCC
FINEPDTNPALIQNQQWATKAVATAAEPGWLEKQTKPEVLEEGDVDKLINDVRDAAEAWA
CCCCCCCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
ARPARERAEILYKTAEILRVRRGHLISVTAAEVGKAVEQTDPEISEAIDFARYYAHLALE
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEE
LDDVDNAEFTPDRVVVVTPPWNFPIAIPAGSTFAALAAGAGVIHKPSKPSQHCSAAVVEA
ECCCCCCCCCCCEEEEEECCCCCCEEECCCCHHHHHHCCCCCEECCCCCHHHHHHHHHHH
LWEAGVPREVLHCIYPANRDVGCALISHEHVDRVILTGSSETAAMFSSWRPELTINGETS
HHHCCCCHHHHHHHCCCCCCCCEEEECHHCCCEEEEECCCHHHHHHHCCCCCEEECCCCC
GKNAIVVTPSADRDLAVADLVKSAFGHAGQKCSAASLGILVGSVYESERFRKQLVDAASS
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVDWPTNPSATVGPLTELPSDKLHHALTTLEEGESWLLKPRQLDDTGRLWSPGIKEGVK
EEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCHHHCCC
PGTFFHLTEVFGPVLGLMKATDLNEAIEFQNGNDFGLTGGLQSLDADEVRTWLDHVDVGN
CCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCH
AYVNRGITGAIVQRQSFGGWKKSSVGLGSKAGGPNYVMLMGTWADAPSHHAPRETNPLIS
HHHHCCCCCHHEEHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHH
KLDLPGEELEWLEKANASDETAWNTEFGSPRDPSGLDVEANIFRYRPAEVVLRLDDSATP
HCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCEEEECCHHEEEEECCCCCH
RETARALLAARRAGVTPRVLQTPGVSEQVREVLSAAGVSAETVDDSVFISNVLRGEYDEN
HHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCCCC
SSVRVRYLGKVSDTVRERLSVRPEVVLLDDAVTASGRVELRYWLKEQAISMTLHRFGNPV
CCEEEEEECHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCHH
AAFHELAEELKR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]