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The map label for this gene is ushA [C]

Identifier: 62388917

GI number: 62388917

Start: 22164

End: 23402

Strand: Direct

Name: ushA [C]

Synonym: cg0035

Alternate gene names: 62388917

Gene position: 22164-23402 (Clockwise)

Preceding gene: 62388916

Following gene: 62388919

Centisome position: 0.68

GC content: 53.43

Gene sequence:

>1239_bases
ATGCAGTCTGGAAACTACGGGCACGCACTTGCCGATGTAGATTTCAGCTTCAACCACGACACCGGTGAGCTCACCGTAGA
TGATGCCCGCATGCTCGGAGTCGACGATATCAACGCGTGTGAAAACCCAGATGACACCATTGCAGATATTGTTGCTCAGG
CGGAACTTGATGCTGGTGAAGCCGGCAAAGAAGTAGTAGCGACCATCGATGGCGATTTTCTCCGCGCCAGCGACGAAGGA
GCAGAATCTGGCTCCAACTACGGCGCTGAATCCCAGCTCGTCAACATGATTGCCAGTGCTGTGCGTTGGTCCATGTCCAC
CAATACCGCCACCACCGCAGACATTGGGCTTATGAACGCCGGAGGACTCCACACTGACCTATTCAGCGGCGATGTTACCT
ACGCCGAAGCTTTTGAAATCCAGCCTTTCTCCGGTGAAGATTCATTTGTCACCCTCAAGGGATCAGACTTCAAAGATGCC
CTTGAGCAGCAGTGGGAAGAAGGTTCTGCACGACCAGTGGCAGCACTTGGCGTATCCGACAACGTTTCCTACACCTACGA
CATCAACCGTCCAATCGGTGACCGCGTCACTTCCGTGACCATTGATGATACCCCACTTGATCCGGAACGCGACTACGTTG
TTGCAGCTTCCCTGTACCTCCAGTCCGGCAACGAAGGTATGACCGCACTGACCCGCGGAACCGCACCTGCACAAACCGGC
ATCGTGGATGTACAGTCCACCATCGGATACTTGTCCAACAACAATGTCACCCCACGTACTGGTCAAGCCCAGATTTCCAT
CACCCCATCCGGTGAGTTCAATGCGGGTGAAACCATCACCCTTGACATGGCAGGACTCCGCTACACCCAAGGCGACACTG
CCACGGAAGTAACTGTCAGCCTTCGAGAAGAAATTGTTTCAGCACCAATTGATCCTCAGCTCGGAGAAGCTGGCTTTGGC
GAAGCTGGAACCGCGACAGTGAGCTTGGACATTCCTGCAACCCTTTCAGGTACTCAAAACCTCGTTGTCACCACCGATAC
CGGCACCCGTATTTCCATGCCAGTTGAGATTGTTGGCGCAGAACAACCAGCACCGCAACCAGCAGGTTCCTCTGTTTTAG
GAACTGGAGTGCTCAGTGGACTCCTCGGCATTGTTGTAGGAATTCTAGGAATGGTCGGTCTGGTGAACTGGATTGACCCA
AGCTTCATTCAACAGATCCAGCAGCAAATCTTTGCTTAA

Upstream 100 bases:

>100_bases
CATTACCGGCACCGAAGCATGGTCAGAAAATATCGACGTTGTTTTCGCAGGTCACACCCACTAAGTTCGTGATCTAGGAA
CCGACAACGGTCCACTAATC

Downstream 100 bases:

>100_bases
ATTTAGTAAAAAGCATGCATCTAGCTGCGGATTTTTAAGAAACGTAGCCTGGGTGTAAAATTTAAAGAGCAAGTTTTTAC
AACTTGCTCTTTAGCTCGGG

Product: hypothetical protein

Products: Phosphate; Uridine [C]

Alternate protein names: 5-Nucleotidase; 5-Nucleotidase Domain Protein; 5-Nucleotidase Family Protein; Secreted 5-Nucleotidase; Nucleotidase; 5-Nucleotidase-Like; 5-Nucleotidase-Like Protein; 5`-Nucleotidase Family Protein; LPXTG-Motif Cell Wall Anchor Domain Protein; 2 3'-Cyclic-Nucleotide 2'-Phosphodiesterase; 5prime Nucleotidase; UDP-Sugar Diphosphatase; 2 3-Cyclic-Nucleotide 2Phosphodiesterase; 5 -Nucleotidase; 5`-Nucleotidase; 5-Nucleotidase/Ser/Thr Protein Phosphatase; 5-Nucleotidase Protein; 5-Nucleotidase/2' 3'-Cyclic Phosphodiesterase; Extracellular Nuclease; Calcineurin-Like Phosphoesterase; 5-Nucleotidase Protein; 5-Nucleotidase/Phosphoesterase; Protein UshA (Two S-Layer Domains

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MQSGNYGHALADVDFSFNHDTGELTVDDARMLGVDDINACENPDDTIADIVAQAELDAGEAGKEVVATIDGDFLRASDEG
AESGSNYGAESQLVNMIASAVRWSMSTNTATTADIGLMNAGGLHTDLFSGDVTYAEAFEIQPFSGEDSFVTLKGSDFKDA
LEQQWEEGSARPVAALGVSDNVSYTYDINRPIGDRVTSVTIDDTPLDPERDYVVAASLYLQSGNEGMTALTRGTAPAQTG
IVDVQSTIGYLSNNNVTPRTGQAQISITPSGEFNAGETITLDMAGLRYTQGDTATEVTVSLREEIVSAPIDPQLGEAGFG
EAGTATVSLDIPATLSGTQNLVVTTDTGTRISMPVEIVGAEQPAPQPAGSSVLGTGVLSGLLGIVVGILGMVGLVNWIDP
SFIQQIQQQIFA

Sequences:

>Translated_412_residues
MQSGNYGHALADVDFSFNHDTGELTVDDARMLGVDDINACENPDDTIADIVAQAELDAGEAGKEVVATIDGDFLRASDEG
AESGSNYGAESQLVNMIASAVRWSMSTNTATTADIGLMNAGGLHTDLFSGDVTYAEAFEIQPFSGEDSFVTLKGSDFKDA
LEQQWEEGSARPVAALGVSDNVSYTYDINRPIGDRVTSVTIDDTPLDPERDYVVAASLYLQSGNEGMTALTRGTAPAQTG
IVDVQSTIGYLSNNNVTPRTGQAQISITPSGEFNAGETITLDMAGLRYTQGDTATEVTVSLREEIVSAPIDPQLGEAGFG
EAGTATVSLDIPATLSGTQNLVVTTDTGTRISMPVEIVGAEQPAPQPAGSSVLGTGVLSGLLGIVVGILGMVGLVNWIDP
SFIQQIQQQIFA
>Mature_412_residues
MQSGNYGHALADVDFSFNHDTGELTVDDARMLGVDDINACENPDDTIADIVAQAELDAGEAGKEVVATIDGDFLRASDEG
AESGSNYGAESQLVNMIASAVRWSMSTNTATTADIGLMNAGGLHTDLFSGDVTYAEAFEIQPFSGEDSFVTLKGSDFKDA
LEQQWEEGSARPVAALGVSDNVSYTYDINRPIGDRVTSVTIDDTPLDPERDYVVAASLYLQSGNEGMTALTRGTAPAQTG
IVDVQSTIGYLSNNNVTPRTGQAQISITPSGEFNAGETITLDMAGLRYTQGDTATEVTVSLREEIVSAPIDPQLGEAGFG
EAGTATVSLDIPATLSGTQNLVVTTDTGTRISMPVEIVGAEQPAPQPAGSSVLGTGVLSGLLGIVVGILGMVGLVNWIDP
SFIQQIQQQIFA

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Drosophila melanogaster, GI24641187, Length=215, Percent_Identity=29.3023255813954, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.45; 3.1.3.5 [C]

Molecular weight: Translated: 43020; Mature: 43020

Theoretical pI: Translated: 3.64; Mature: 3.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSGNYGHALADVDFSFNHDTGELTVDDARMLGVDDINACENPDDTIADIVAQAELDAGE
CCCCCCCCEEEEEEEEECCCCCCEEECCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCC
AGKEVVATIDGDFLRASDEGAESGSNYGAESQLVNMIASAVRWSMSTNTATTADIGLMNA
CCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
GGLHTDLFSGDVTYAEAFEIQPFSGEDSFVTLKGSDFKDALEQQWEEGSARPVAALGVSD
CCCCEECCCCCCEEEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEECCC
NVSYTYDINRPIGDRVTSVTIDDTPLDPERDYVVAASLYLQSGNEGMTALTRGTAPAQTG
CCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCC
IVDVQSTIGYLSNNNVTPRTGQAQISITPSGEFNAGETITLDMAGLRYTQGDTATEVTVS
EEEHHHHHHECCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCEEEECCCCCCEEHHH
LREEIVSAPIDPQLGEAGFGEAGTATVSLDIPATLSGTQNLVVTTDTGTRISMPVEIVGA
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCEEECCCCEEEEEECCCCEEECCEEEEEC
EQPAPQPAGSSVLGTGVLSGLLGIVVGILGMVGLVNWIDPSFIQQIQQQIFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQSGNYGHALADVDFSFNHDTGELTVDDARMLGVDDINACENPDDTIADIVAQAELDAGE
CCCCCCCCEEEEEEEEECCCCCCEEECCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCC
AGKEVVATIDGDFLRASDEGAESGSNYGAESQLVNMIASAVRWSMSTNTATTADIGLMNA
CCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
GGLHTDLFSGDVTYAEAFEIQPFSGEDSFVTLKGSDFKDALEQQWEEGSARPVAALGVSD
CCCCEECCCCCCEEEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEECCC
NVSYTYDINRPIGDRVTSVTIDDTPLDPERDYVVAASLYLQSGNEGMTALTRGTAPAQTG
CCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCC
IVDVQSTIGYLSNNNVTPRTGQAQISITPSGEFNAGETITLDMAGLRYTQGDTATEVTVS
EEEHHHHHHECCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCEEEECCCCCCEEHHH
LREEIVSAPIDPQLGEAGFGEAGTATVSLDIPATLSGTQNLVVTTDTGTRISMPVEIVGA
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCEEECCCCEEEEEECCCCEEECCEEEEEC
EQPAPQPAGSSVLGTGVLSGLLGIVVGILGMVGLVNWIDPSFIQQIQQQIFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; UMP [C]

Specific reaction: H2O + UMP --> Phosphate + Uridine [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Inhibitor from Salmonella typhimurium cytoplasm [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA