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The map label for this gene is yhcR [H]

Identifier: 62388916

GI number: 62388916

Start: 21597

End: 22127

Strand: Direct

Name: yhcR [H]

Synonym: cg0034

Alternate gene names: 62388916

Gene position: 21597-22127 (Clockwise)

Preceding gene: 62388915

Following gene: 62388917

Centisome position: 0.66

GC content: 50.09

Gene sequence:

>531_bases
ATGCTGAAATGTGCAGTCGATGAAGCCGCTGGCGGACGCGCCCAAGCTTTCGTATCCTCAGGCGATAACATTGGTGGCAG
CCCGTTCCAATCCTCCATTCTTGGTGATGAACCCACCTTGGAAGCACTCAACCAAATGGGTCTTGATTACTCAGCAGTGG
GCAACCACGAATTTGATAAAGGCTACGCAGACTTAAGCAGTCGAGTCGCTGACCTTGCTGATTTTGATTATCTCGGCGCA
AACGTTGAGGGCGAAAACCCAGATCTTGCACCATATGGAATTTCTCACCTTGATGGTGTGAAGGTTGCTTTCGTAGGCAC
CGTATCCCAAGAAACTCCGATGTTGGTCAATTCTGAAGGCATTGAGGGAATCACGTTTACTGACCCACTTGAAGCAACCA
ACCGTGTAGCTGATGAACTCGTGGGAAGTGGCGCAGCAGATGTTGTCGTTGCGCTTTACCACGAAGGCATTACCGGCACC
GAAGCATGGTCAGAAAATATCGACGTTGTTTTCGCAGGTCACACCCACTAA

Upstream 100 bases:

>100_bases
TATTGTCCAGGCGCAGGAAAATATCTCATAGTTCAACATCGCAAATATCACCGACTTCCACGGCTATATCTCTGCAACTG
CAGCTCACCCCGGTGCAGCA

Downstream 100 bases:

>100_bases
GTTCGTGATCTAGGAACCGACAACGGTCCACTAATCATGCAGTCTGGAAACTACGGGCACGCACTTGCCGATGTAGATTT
CAGCTTCAACCACGACACCG

Product: hypothetical protein

Products: ribonucleoside; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MLKCAVDEAAGGRAQAFVSSGDNIGGSPFQSSILGDEPTLEALNQMGLDYSAVGNHEFDKGYADLSSRVADLADFDYLGA
NVEGENPDLAPYGISHLDGVKVAFVGTVSQETPMLVNSEGIEGITFTDPLEATNRVADELVGSGAADVVVALYHEGITGT
EAWSENIDVVFAGHTH

Sequences:

>Translated_176_residues
MLKCAVDEAAGGRAQAFVSSGDNIGGSPFQSSILGDEPTLEALNQMGLDYSAVGNHEFDKGYADLSSRVADLADFDYLGA
NVEGENPDLAPYGISHLDGVKVAFVGTVSQETPMLVNSEGIEGITFTDPLEATNRVADELVGSGAADVVVALYHEGITGT
EAWSENIDVVFAGHTH
>Mature_176_residues
MLKCAVDEAAGGRAQAFVSSGDNIGGSPFQSSILGDEPTLEALNQMGLDYSAVGNHEFDKGYADLSSRVADLADFDYLGA
NVEGENPDLAPYGISHLDGVKVAFVGTVSQETPMLVNSEGIEGITFTDPLEATNRVADELVGSGAADVVVALYHEGITGT
EAWSENIDVVFAGHTH

Specific function: Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected, using 5'-AMP as the substrate, in the presence of diverse divalent metals and with various pH values [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TNase-like domain [H]

Homologues:

Organism=Escherichia coli, GI1786687, Length=151, Percent_Identity=29.1390728476821, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR016071
- InterPro:   IPR006021 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00746 Gram_pos_anchor; PF00149 Metallophos; PF00565 SNase; PF01336 tRNA_anti [H]

EC number: 3.1.3.5

Molecular weight: Translated: 18351; Mature: 18351

Theoretical pI: Translated: 3.80; Mature: 3.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKCAVDEAAGGRAQAFVSSGDNIGGSPFQSSILGDEPTLEALNQMGLDYSAVGNHEFDK
CCEECCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCEECCCCCCCCC
GYADLSSRVADLADFDYLGANVEGENPDLAPYGISHLDGVKVAFVGTVSQETPMLVNSEG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCC
IEGITFTDPLEATNRVADELVGSGAADVVVALYHEGITGTEAWSENIDVVFAGHTH
CCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure
MLKCAVDEAAGGRAQAFVSSGDNIGGSPFQSSILGDEPTLEALNQMGLDYSAVGNHEFDK
CCEECCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCEECCCCCCCCC
GYADLSSRVADLADFDYLGANVEGENPDLAPYGISHLDGVKVAFVGTVSQETPMLVNSEG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCC
IEGITFTDPLEATNRVADELVGSGAADVVVALYHEGITGTEAWSENIDVVFAGHTH
CCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5'-ribonucleotide; H2O

Specific reaction: A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]