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The map label for this gene is trxB [H]

Identifier: 62185083

GI number: 62185083

Start: 523775

End: 524710

Strand: Direct

Name: trxB [H]

Synonym: CAB454

Alternate gene names: 62185083

Gene position: 523775-524710 (Clockwise)

Preceding gene: 62185076

Following gene: 62185086

Centisome position: 45.77

GC content: 40.71

Gene sequence:

>936_bases
ATGACTTACGCTAAAGTAATTATTATCGGCTCTGGCCCTGCAGGTTATACTGCAGCGATTTATGCTTCAAGAGCACTTTT
AAGTCCTATTTTATTCGAGGGCTTTTTTTCCGGTGTTGCCGGTGGTCAATTAATGACTACTACTGAAGTAGAAAATTTCC
CTGGATTCCCTGAAGGCATACTAGGTCCAAAATTAATGGAGAATATGAAATCCCAGTCTAGTCGTTTTGGAACTCAAATT
CTTCCAAAAGATGTGACTTCAGTGGATTTCACTATACGTCCTTTTGTAGTAATGTCCAACGAAGAAAAATATACCTGTGA
CGCGTGTATTATAGCAACGGGAGCTTCTGCAAAGCGTTTAGAAATTCCCGGAGCCGCTGACAACGAATTCTGGCAAAAAG
GCGTTACAGCTTGTGCTGTGTGTGACGGCGCCTCTCCTATTTTTAAAAATAAAGACTTGTATGTTATTGGCGGTGGAGAT
TCTGCTTTAGAAGAAGCAATTTTTCTGACTCGGTATGGAAAGCGTGTCTTTGTGGTACATAGAAGGGATACGTTAAGAGC
TTCTAAAGCGATGATAAAAAAGGCAGAGTCGAATGAAAAGATCTCTTTCCTTTGGAATAGTTCAATAGTAAAAATTTCCG
GAGATACCTTTGTTCGTTCTGTTGATATTTTAAACAATGTTTCTAAAGAGGTTTCTACTCGGGATGCAGGAGGCGTATTT
TTTGCTATAGGACATAGGCCGAATACGGATTTCTTAGGTGGTCAGCTAGCTTTAGATGAACATGGTTATATCATTACTGA
ACCAGGTACTTGCAGAACCTCTATTCCAGGAGTATTTGCTGCTGGGGATGTTCAGGATAAACATTATCGACAAGCCATCA
TAGCTGCGGGCAGTGGGTGTATGGCTGCTTTAGAGGCCGAACGTTTCTTAAATTAA

Upstream 100 bases:

>100_bases
AGATCTCCCTTGCAGCAGTTTTTTTATGCTAATTTGTTGCTTTAAAATTTTTTATTTGTTTTAGATTTATTTCTAAAATT
ATTCGGTAGGGTAAAAATAA

Downstream 100 bases:

>100_bases
TGCTATTGCCATAGCTGTGGCGTACTCACGACTATGGCTGATTGATAACAAGACTTTGGAGATTCCTAATTTTTGATACA
CCCTTTCTGGTAAAAAGACT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTYAKVIIIGSGPAGYTAAIYASRALLSPILFEGFFSGVAGGQLMTTTEVENFPGFPEGILGPKLMENMKSQSSRFGTQI
LPKDVTSVDFTIRPFVVMSNEEKYTCDACIIATGASAKRLEIPGAADNEFWQKGVTACAVCDGASPIFKNKDLYVIGGGD
SALEEAIFLTRYGKRVFVVHRRDTLRASKAMIKKAESNEKISFLWNSSIVKISGDTFVRSVDILNNVSKEVSTRDAGGVF
FAIGHRPNTDFLGGQLALDEHGYIITEPGTCRTSIPGVFAAGDVQDKHYRQAIIAAGSGCMAALEAERFLN

Sequences:

>Translated_311_residues
MTYAKVIIIGSGPAGYTAAIYASRALLSPILFEGFFSGVAGGQLMTTTEVENFPGFPEGILGPKLMENMKSQSSRFGTQI
LPKDVTSVDFTIRPFVVMSNEEKYTCDACIIATGASAKRLEIPGAADNEFWQKGVTACAVCDGASPIFKNKDLYVIGGGD
SALEEAIFLTRYGKRVFVVHRRDTLRASKAMIKKAESNEKISFLWNSSIVKISGDTFVRSVDILNNVSKEVSTRDAGGVF
FAIGHRPNTDFLGGQLALDEHGYIITEPGTCRTSIPGVFAAGDVQDKHYRQAIIAAGSGCMAALEAERFLN
>Mature_310_residues
TYAKVIIIGSGPAGYTAAIYASRALLSPILFEGFFSGVAGGQLMTTTEVENFPGFPEGILGPKLMENMKSQSSRFGTQIL
PKDVTSVDFTIRPFVVMSNEEKYTCDACIIATGASAKRLEIPGAADNEFWQKGVTACAVCDGASPIFKNKDLYVIGGGDS
ALEEAIFLTRYGKRVFVVHRRDTLRASKAMIKKAESNEKISFLWNSSIVKISGDTFVRSVDILNNVSKEVSTRDAGGVFF
AIGHRPNTDFLGGQLALDEHGYIITEPGTCRTSIPGVFAAGDVQDKHYRQAIIAAGSGCMAALEAERFLN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=47.8125, Blast_Score=281, Evalue=3e-77,
Organism=Escherichia coli, GI87081763, Length=314, Percent_Identity=32.484076433121, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320560, Length=318, Percent_Identity=55.0314465408805, Blast_Score=352, Evalue=6e-98,
Organism=Saccharomyces cerevisiae, GI6321898, Length=318, Percent_Identity=51.8867924528302, Blast_Score=328, Evalue=5e-91,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33496; Mature: 33364

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYAKVIIIGSGPAGYTAAIYASRALLSPILFEGFFSGVAGGQLMTTTEVENFPGFPEGI
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
LGPKLMENMKSQSSRFGTQILPKDVTSVDFTIRPFVVMSNEEKYTCDACIIATGASAKRL
CCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEEEECCCCCCEE
EIPGAADNEFWQKGVTACAVCDGASPIFKNKDLYVIGGGDSALEEAIFLTRYGKRVFVVH
ECCCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHEECCCEEEEEE
RRDTLRASKAMIKKAESNEKISFLWNSSIVKISGDTFVRSVDILNNVSKEVSTRDAGGVF
CCHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEE
FAIGHRPNTDFLGGQLALDEHGYIITEPGTCRTSIPGVFAAGDVQDKHYRQAIIAAGSGC
EEECCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHEECCCCH
MAALEAERFLN
HHHHHHHHHCC
>Mature Secondary Structure 
TYAKVIIIGSGPAGYTAAIYASRALLSPILFEGFFSGVAGGQLMTTTEVENFPGFPEGI
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
LGPKLMENMKSQSSRFGTQILPKDVTSVDFTIRPFVVMSNEEKYTCDACIIATGASAKRL
CCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEEEECCCCCCEE
EIPGAADNEFWQKGVTACAVCDGASPIFKNKDLYVIGGGDSALEEAIFLTRYGKRVFVVH
ECCCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHEECCCEEEEEE
RRDTLRASKAMIKKAESNEKISFLWNSSIVKISGDTFVRSVDILNNVSKEVSTRDAGGVF
CCHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEE
FAIGHRPNTDFLGGQLALDEHGYIITEPGTCRTSIPGVFAAGDVQDKHYRQAIIAAGSGC
EEECCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHEECCCCH
MAALEAERFLN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]