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The map label for this gene is yaeL [C]

Identifier: 62185057

GI number: 62185057

Start: 493376

End: 495244

Strand: Direct

Name: yaeL [C]

Synonym: CAB428

Alternate gene names: 62185057

Gene position: 493376-495244 (Clockwise)

Preceding gene: 62185056

Following gene: 62185061

Centisome position: 43.11

GC content: 39.33

Gene sequence:

>1869_bases
ATGACAATAATATATTTCATTCTTGCAGCCCTTGCTTTGGGGGTTTTAGTATTGGTTCATGAATTGGGTCATTTACTGGC
AGCCAAGTCTGTAGGCATGGCTGTGGAGAGTTTTAGTATTGGTTTTGGTCCAACTTTATATAAAAAGAAGATTGGCAATA
TAGAGTATCGTATAGGTATTTTCCCATTTGGGGGATATGTCCGAATTAAAGGCATGGACAAGAGAGAAAAAGGTGTAGAT
GTAGACCCTGATTCCGTTTATGACATACCTCAAGGTTTTTTCAGTAAATCTCCATGGAAAAGAATCTTCGTTCTTGCTGC
TGGTCCTATAGCTAATGTTTTGTTAGCTTTTGTAGCTTTTGGTGCCTTATATATTTCTGGAGGAAGAAGTAAAGCATACT
CTGAGTATTCTCGTATTGTGGGCTGGGTAAATCCTATTTTAAAAGAGAAAGGTTTGGCTCTTGGCGACGAGATCCTTACG
TGTAATGGTAAGCCTTATTACTCAGATAAAGATGCAATTACTTCCGCTTTATTAGACGGGCGTTTGTCATTTACGGGAGT
GCACCCTGGATATCTTTCGGAAACTTCTAGTGATTTTGCCTTCAATACAGAATTCGATGTTAATAAAAATGGTATTCCTC
TAGCAGGAGCTAGCTATCTTTTATACCGTCATCAGGAGCCGATTTCCAAGGAATCTCCTCTGTATTCAGCGAATATACTT
CCAGGTGATCGCTTAGTGTGGATGGATGGGCAAATCCTGTTTTCTCCAATGCAGGTTTCACAGATACTGAATGAGGCTTA
TGCTTTTGTTAAGGTTTCTCGTCACAATAAGGAATTTTCGGTACGTATTCCGAGAATATTAGTGAGTACACTGTACCTTT
CTCCTTATGTCAGGAATGAACTTATCGATAATCAGTATGAGGCTGGGATTAAGGGGAAATGGTCTTCTTTATATACTTTA
CCGTATGTGATTAATAGCTACGGCTATGTAGAAGGGGAATTACAACCGATCGATCCAGAGTCTCCATTTCCTTCTATGGA
AGAAAAACTGGAATTGGGGGATCGAATTATTGCGATAGACGGTACTCCCGTTAGTGGAAGCACGGACATTTTACGTTTAG
TTCAGAATCATAAGGTATCGATTATTGTTCAGAAAATGACTCCTGAGCAATTAGAGGATGTGGATTCCTCCCTTGCTGAT
AAGCGATTTATTCATTCCTACAATGCTCAAGATTTATTAGCGATTATTCATTCTATAGGGAGTACTCAAGAAGTACGCGA
ATCAGGACAATATCGGTTATTGCCTCCCGTGCATCCTAAGCCTTGGGTGAGCATTTATTCCGACGATCTTTTGAATAAGC
GTCGTGAAATGGCGAAGAGATTCAAAAATCAAGATCAGCAGCGGTACTATCTCGATAGAATAGAAATAGAAAAACAAAGG
TTATCTTTAGGGATTCCTTTAAGGGATATGACTGTGAAGTATAATCCTAGACCGGATGTCTTAATTGCGCATATTGCTAA
GGATAGTCTGCGTACTATGAAAGCATTAGTTGTAGGCCGGCTGAATCCTCAATGGTTATCAGGACCTGTGGGGATTGTTC
ATATGTTACATAAGGGGTGGTCGCTAGGAATAGCAGAAGCTTTGTTTTGGATAGGGCTAGTAAGTATCAATCTAGCTGTT
TTGAATCTCCTTCCAATTCCTGTATTAGATGGCGGCTATATTGTACTTTGCCTATGGGAGATGATCACAAGACGGCGTTT
GAGTATGAAACTTATTGAGAGGATGTTAATACCATTTTCTTTATTATTAATAGCCTTCTTTATTTTTCTAACGTTTCAGG
ATTTGTTTCGCTTTTTTGCAGTGAGTTAG

Upstream 100 bases:

>100_bases
GAAAAATCATAGAGTTTCTTCGTGCACCTCGTTAGATGATGTCTTTTCTGTTGATAAAGAAGCTCGAGCTCTTGCTCAAG
AGATATAACCTGGTACGTAT

Downstream 100 bases:

>100_bases
GTTTCCAGATTTTAGGAAATCCATAAAGGTTATAAGGATGAGAACCAAAACAATGGATAATATAAATATCTTTGTTTTTG
TTTGTATTCAACCTAGAGCT

Product: putative metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MTIIYFILAALALGVLVLVHELGHLLAAKSVGMAVESFSIGFGPTLYKKKIGNIEYRIGIFPFGGYVRIKGMDKREKGVD
VDPDSVYDIPQGFFSKSPWKRIFVLAAGPIANVLLAFVAFGALYISGGRSKAYSEYSRIVGWVNPILKEKGLALGDEILT
CNGKPYYSDKDAITSALLDGRLSFTGVHPGYLSETSSDFAFNTEFDVNKNGIPLAGASYLLYRHQEPISKESPLYSANIL
PGDRLVWMDGQILFSPMQVSQILNEAYAFVKVSRHNKEFSVRIPRILVSTLYLSPYVRNELIDNQYEAGIKGKWSSLYTL
PYVINSYGYVEGELQPIDPESPFPSMEEKLELGDRIIAIDGTPVSGSTDILRLVQNHKVSIIVQKMTPEQLEDVDSSLAD
KRFIHSYNAQDLLAIIHSIGSTQEVRESGQYRLLPPVHPKPWVSIYSDDLLNKRREMAKRFKNQDQQRYYLDRIEIEKQR
LSLGIPLRDMTVKYNPRPDVLIAHIAKDSLRTMKALVVGRLNPQWLSGPVGIVHMLHKGWSLGIAEALFWIGLVSINLAV
LNLLPIPVLDGGYIVLCLWEMITRRRLSMKLIERMLIPFSLLLIAFFIFLTFQDLFRFFAVS

Sequences:

>Translated_622_residues
MTIIYFILAALALGVLVLVHELGHLLAAKSVGMAVESFSIGFGPTLYKKKIGNIEYRIGIFPFGGYVRIKGMDKREKGVD
VDPDSVYDIPQGFFSKSPWKRIFVLAAGPIANVLLAFVAFGALYISGGRSKAYSEYSRIVGWVNPILKEKGLALGDEILT
CNGKPYYSDKDAITSALLDGRLSFTGVHPGYLSETSSDFAFNTEFDVNKNGIPLAGASYLLYRHQEPISKESPLYSANIL
PGDRLVWMDGQILFSPMQVSQILNEAYAFVKVSRHNKEFSVRIPRILVSTLYLSPYVRNELIDNQYEAGIKGKWSSLYTL
PYVINSYGYVEGELQPIDPESPFPSMEEKLELGDRIIAIDGTPVSGSTDILRLVQNHKVSIIVQKMTPEQLEDVDSSLAD
KRFIHSYNAQDLLAIIHSIGSTQEVRESGQYRLLPPVHPKPWVSIYSDDLLNKRREMAKRFKNQDQQRYYLDRIEIEKQR
LSLGIPLRDMTVKYNPRPDVLIAHIAKDSLRTMKALVVGRLNPQWLSGPVGIVHMLHKGWSLGIAEALFWIGLVSINLAV
LNLLPIPVLDGGYIVLCLWEMITRRRLSMKLIERMLIPFSLLLIAFFIFLTFQDLFRFFAVS
>Mature_621_residues
TIIYFILAALALGVLVLVHELGHLLAAKSVGMAVESFSIGFGPTLYKKKIGNIEYRIGIFPFGGYVRIKGMDKREKGVDV
DPDSVYDIPQGFFSKSPWKRIFVLAAGPIANVLLAFVAFGALYISGGRSKAYSEYSRIVGWVNPILKEKGLALGDEILTC
NGKPYYSDKDAITSALLDGRLSFTGVHPGYLSETSSDFAFNTEFDVNKNGIPLAGASYLLYRHQEPISKESPLYSANILP
GDRLVWMDGQILFSPMQVSQILNEAYAFVKVSRHNKEFSVRIPRILVSTLYLSPYVRNELIDNQYEAGIKGKWSSLYTLP
YVINSYGYVEGELQPIDPESPFPSMEEKLELGDRIIAIDGTPVSGSTDILRLVQNHKVSIIVQKMTPEQLEDVDSSLADK
RFIHSYNAQDLLAIIHSIGSTQEVRESGQYRLLPPVHPKPWVSIYSDDLLNKRREMAKRFKNQDQQRYYLDRIEIEKQRL
SLGIPLRDMTVKYNPRPDVLIAHIAKDSLRTMKALVVGRLNPQWLSGPVGIVHMLHKGWSLGIAEALFWIGLVSINLAVL
NLLPIPVLDGGYIVLCLWEMITRRRLSMKLIERMLIPFSLLLIAFFIFLTFQDLFRFFAVS

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M50B family [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=258, Percent_Identity=32.9457364341085, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 70081; Mature: 69949

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIYFILAALALGVLVLVHELGHLLAAKSVGMAVESFSIGFGPTLYKKKIGNIEYRIGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEEE
FPFGGYVRIKGMDKREKGVDVDPDSVYDIPQGFFSKSPWKRIFVLAAGPIANVLLAFVAF
EECCCEEEEECCCCCCCCCCCCCCCHHHCCHHHCCCCCCCEEEEEECCHHHHHHHHHHHH
GALYISGGRSKAYSEYSRIVGWVNPILKEKGLALGDEILTCNGKPYYSDKDAITSALLDG
HHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHCC
RLSFTGVHPGYLSETSSDFAFNTEFDVNKNGIPLAGASYLLYRHQEPISKESPLYSANIL
CCEEEECCCCCCCCCCCCCEECCEECCCCCCCCCCCCHHEEEECCCCCCCCCCCEEEECC
PGDRLVWMDGQILFSPMQVSQILNEAYAFVKVSRHNKEFSVRIPRILVSTLYLSPYVRNE
CCCEEEEECCCEEECHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHHHCHHHHHH
LIDNQYEAGIKGKWSSLYTLPYVINSYGYVEGELQPIDPESPFPSMEEKLELGDRIIAID
HHCCHHCCCCCCCCCCEEEHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHCCCEEEEEC
GTPVSGSTDILRLVQNHKVSIIVQKMTPEQLEDVDSSLADKRFIHSYNAQDLLAIIHSIG
CCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
STQEVRESGQYRLLPPVHPKPWVSIYSDDLLNKRREMAKRFKNQDQQRYYLDRIEIEKQR
CCHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LSLGIPLRDMTVKYNPRPDVLIAHIAKDSLRTMKALVVGRLNPQWLSGPVGIVHMLHKGW
HHCCCCEECCEEEECCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCC
SLGIAEALFWIGLVSINLAVLNLLPIPVLDGGYIVLCLWEMITRRRLSMKLIERMLIPFS
CHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLIAFFIFLTFQDLFRFFAVS
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIIYFILAALALGVLVLVHELGHLLAAKSVGMAVESFSIGFGPTLYKKKIGNIEYRIGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEEE
FPFGGYVRIKGMDKREKGVDVDPDSVYDIPQGFFSKSPWKRIFVLAAGPIANVLLAFVAF
EECCCEEEEECCCCCCCCCCCCCCCHHHCCHHHCCCCCCCEEEEEECCHHHHHHHHHHHH
GALYISGGRSKAYSEYSRIVGWVNPILKEKGLALGDEILTCNGKPYYSDKDAITSALLDG
HHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHCC
RLSFTGVHPGYLSETSSDFAFNTEFDVNKNGIPLAGASYLLYRHQEPISKESPLYSANIL
CCEEEECCCCCCCCCCCCCEECCEECCCCCCCCCCCCHHEEEECCCCCCCCCCCEEEECC
PGDRLVWMDGQILFSPMQVSQILNEAYAFVKVSRHNKEFSVRIPRILVSTLYLSPYVRNE
CCCEEEEECCCEEECHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHHHCHHHHHH
LIDNQYEAGIKGKWSSLYTLPYVINSYGYVEGELQPIDPESPFPSMEEKLELGDRIIAID
HHCCHHCCCCCCCCCCEEEHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHCCCEEEEEC
GTPVSGSTDILRLVQNHKVSIIVQKMTPEQLEDVDSSLADKRFIHSYNAQDLLAIIHSIG
CCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
STQEVRESGQYRLLPPVHPKPWVSIYSDDLLNKRREMAKRFKNQDQQRYYLDRIEIEKQR
CCHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LSLGIPLRDMTVKYNPRPDVLIAHIAKDSLRTMKALVVGRLNPQWLSGPVGIVHMLHKGW
HHCCCCEECCEEEECCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCC
SLGIAEALFWIGLVSINLAVLNLLPIPVLDGGYIVLCLWEMITRRRLSMKLIERMLIPFS
CHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLIAFFIFLTFQDLFRFFAVS
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]