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The map label for this gene is ptsH [H]

Identifier: 62184954

GI number: 62184954

Start: 376900

End: 377241

Strand: Direct

Name: ptsH [H]

Synonym: CAB324

Alternate gene names: 62184954

Gene position: 376900-377241 (Clockwise)

Preceding gene: 62184953

Following gene: 62184955

Centisome position: 32.93

GC content: 42.4

Gene sequence:

>342_bases
GTGGATGAATGTAGAGACTGTGTTTTAGATATCGAGAATCCGGAAGAGCCTGTGGATTTTGCTAACGAGGAAGAAGAAGT
CACATGTATCTGTGTTGTAAAAAACACTTCGGGAATCCATGTGCGTCCTGCGGGAGCTATCGTCAAGTTGTTTGAGGGTG
AAGAATGTGAGGTAAATTTTACCTACGCAGGGAAGACGGTAAATGCCAAAAGTATCATGAGCATACTTATACTAGGAGCT
CCACAAAACGGAGAGATTTTAGTGCGTATTAAAGGGAAAGATGCAAGTCGGGTATTGCAAAAAGTGCAGAATGCCTTTGA
CTCAGGTTTTGGAGAGTTGTAA

Upstream 100 bases:

>100_bases
CGAACTTTAGGAAGTATTGAACTTTTACATTTAACTACAAGTCACTATCCTTCTTTCATTTCTTGGCTAGAAAATTACTT
GCATAGCGAGGAGGTGTATA

Downstream 100 bases:

>100_bases
ATGAACACACCCACGCCTTCTCTAGAGCAAAATAAGGAATGGCGAGTTCCTGGAATGACTTTAGTTCCTGGGGTAGCTAT
AGGAAAAGCATTTTTCTTAG

Product: putative phosphotransferase system, phosphocarrier protein

Products: fructose-6-phosphate [Cytoplasm]; pyruvate; fructose-1-phosphate [Cytoplasm] [C]

Alternate protein names: Histidine-containing protein [H]

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MDECRDCVLDIENPEEPVDFANEEEEVTCICVVKNTSGIHVRPAGAIVKLFEGEECEVNFTYAGKTVNAKSIMSILILGA
PQNGEILVRIKGKDASRVLQKVQNAFDSGFGEL

Sequences:

>Translated_113_residues
MDECRDCVLDIENPEEPVDFANEEEEVTCICVVKNTSGIHVRPAGAIVKLFEGEECEVNFTYAGKTVNAKSIMSILILGA
PQNGEILVRIKGKDASRVLQKVQNAFDSGFGEL
>Mature_113_residues
MDECRDCVLDIENPEEPVDFANEEEEVTCICVVKNTSGIHVRPAGAIVKLFEGEECEVNFTYAGKTVNAKSIMSILILGA
PQNGEILVRIKGKDASRVLQKVQNAFDSGFGEL

Specific function: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their tr

COG id: COG1925

COG function: function code G; Phosphotransferase system, HPr-related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPr domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005698
- InterPro:   IPR000032
- InterPro:   IPR002114 [H]

Pfam domain/function: PF00381 PTS-HPr [H]

EC number: 2.7.1.69 [C]

Molecular weight: Translated: 12346; Mature: 12346

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDECRDCVLDIENPEEPVDFANEEEEVTCICVVKNTSGIHVRPAGAIVKLFEGEECEVNF
CCCHHCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCEEEEEECCCCEEEEE
TYAGKTVNAKSIMSILILGAPQNGEILVRIKGKDASRVLQKVQNAFDSGFGEL
EECCCEECHHHEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDECRDCVLDIENPEEPVDFANEEEEVTCICVVKNTSGIHVRPAGAIVKLFEGEECEVNF
CCCHHCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCEEEEEECCCCEEEEE
TYAGKTVNAKSIMSILILGAPQNGEILVRIKGKDASRVLQKVQNAFDSGFGEL
EECCCEECHHHEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fructose [Periplasm]; phosphoenolpyruvate [C]

Specific reaction: phosphoenolpyruvate + fructose [Periplasm] = fructose-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + fructose [Periplasm] = fructose-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]