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The map label for this gene is bfmBAB [H]

Identifier: 62184951

GI number: 62184951

Start: 371541

End: 373577

Strand: Direct

Name: bfmBAB [H]

Synonym: CAB319

Alternate gene names: 62184951

Gene position: 371541-373577 (Clockwise)

Preceding gene: 62184950

Following gene: 62184953

Centisome position: 32.47

GC content: 43.59

Gene sequence:

>2037_bases
ATGGTAGCAATACAGCATGAATTAGGATCTTCGATTAAAGAAGTTCTGAAATTGGTCTGGAGTTTAAGATTTGCTGAAAA
TAAGATGCTCCTTCTTTCCCGCCAGAGCGATTCTGGAGGAACTTTCCAGTTGTCTTGTGCTGGTCACGAGCTTGTTGGAG
TGGTGGCCGGGAAAAGTCTCCTTCGAGGGAAGGATTGGTCTTTCCCATATTATAGGGATCAAGGATTCCCTGTAGGTCTA
GGGTGTGATCTTTCTGAGATTTTTGCTTCCTTTCTTGGGCGATTAGCTCCGAACCATTCTTCTGGTAGGATGATGCCCTA
CCACTATTCTCATAAAAAACTCCGTATTTGTTGCCAATCGAGTGTAGTAGGTTCCCAATTTCTTCAGGCAGCGGGGCGCG
CATGGGCTGTAAAACATACCAAATCTAACGAAGTCGTTTACGTCTCTGGAGGGGATGGATCCACTTCTCAAGGTGAATTC
CACGAGATGTTAAACTATGTTGCGTTGCATAAGTTGCCCTTAGTCACCGTCGTACAGAATAATGCTTGGGCGATCTCCGT
GCCTTTTAAAGATCAGTGTTCTACAGATTTAGTGCGTTTAGGGGAGAGTTATCAAGGTCTCTCTGTTTATGAAGTTGATG
GCGGGGATTACTTTAAGCTTGTAGATACTTTTTCTAAAGCTGTAGATCAAGCTAGACATACCTCGGTTCCTGCGTTAATT
CTAGTCGATGTTATGCGTTTAGAGCCGCATAGCAACTCTGATAATCATGAGAAATATCGCAGTCGTGAAGATTTAGATCA
TTGTAAGAGTCATGATCCTTTAATCCGGTTAGAACGGCTGATGATAGACGAATGCGGCATTTCACCTGCGGAGATTTTAG
ACATAAAAGCAGAGGCTGAAGCCGAAGTCACTCGTGCTTGTGAAATCGCTGAGGGGATGCCCTTCCCCAGTAAAGGTTCT
ACGAGCCATGATGTATTTTCTCCACATACAACTTCTTTAATTGATTATGAAAATTCTTTAGAAGCTCAGCGTTTGCGTGA
CACTCAACCCAAAGTTATGCGAGATGCCATTACAGAAGCGCTCATTGAAGAAATGAGCCGAGATTCTGGTGTGGTTGTTT
TCGGTGAAGACGTGGCTGGAGATAAAGGTGGGGTTTTTGGTGTCACTAGAAATCTTACAGATAGGTTTGGCAGCGAACGT
TGTTTTAATACACCGTTAGCAGAGGCTACCATTATAGGCACAGCTATTGGTATGGCGATGGATGGGATCCATAAGCCTGT
TGCTGAGATTCAGTTTGCTGATTATATCTGGCCCGGCATTAATCAATTATTTTCTGAAGCTTCGAGTATTTACTACCGTT
CTGCTGGTGAGTGGGAAGTGCCTTTAGTTATTCGTGCTCCTTGTGGAGGTTACATACAAGGTGGCCCTTACCATTCACAA
AGTATAGAAGCGTTCTTAGCCCATTGCCCGGGCATCAAGGTGGCTTATCCATCCAATGCCGCAGATGCAAAAGCCTTGTT
AAAAGCGGCGATTCGCGATCCTAACCCTGTGGTTTTTTTAGAACACAAGGCGCTGTATCAACGACGTATTTTTAGTGCGT
GTCCGGTATTTTCTTCGGATTATGTTTTGCCTTTTGGTAAAGCAGCGATCACGCAAGTCGGTTCAGATTTGACCATTGTT
TCTTGGGGAATGTCTTTAGTTATGAGTATGGAAGTAGCTAAGGAATTGGCAGCTTTAGATATTTCTGCAGAGGTTATAGA
TTTACGTACGATAGTACCTTGTGATTTTTCTACTGTTATAGAGTCTGTTAAGAAAACTAGTAAGTTACTTATAGCTCATG
AAGCGTCGGAGTTTTGTGGGTTTGGTGCAGAGCTTGCTGCAACTGTAGCAGAGCAAGCATATGCATACCTAGATGCACCT
ATTAGGCGTGTTGCGGGATTACATGCCCCAGTTCCTTACTCAAAAATACTGGAAAACGAAGTTCTCCCTCAGAAGGAGAA
AATCTTTCAAGCAGCGAAGAGTTTAGCCGAGTTTTAA

Upstream 100 bases:

>100_bases
AATTTCCCTAAGAAACGCAGTTTCTTGGATAAAATTAAGGGTTTTTTTTCTGACCTCACCGTATAGATAAGGATAGCACA
GATCTATCCGAGGAGCACAT

Downstream 100 bases:

>100_bases
TTGCGATTTTTATTAAATGCTTCCTGTAAGACCAATAATAGTGGAAGTTCTTTTAAGTGATTTACAGTAATTTGTACTAC
TGTCCTTTTTTTGTTTTTTT

Product: putative oxidoreductase

Products: NA

Alternate protein names: Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDH E1-beta [H]

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MVAIQHELGSSIKEVLKLVWSLRFAENKMLLLSRQSDSGGTFQLSCAGHELVGVVAGKSLLRGKDWSFPYYRDQGFPVGL
GCDLSEIFASFLGRLAPNHSSGRMMPYHYSHKKLRICCQSSVVGSQFLQAAGRAWAVKHTKSNEVVYVSGGDGSTSQGEF
HEMLNYVALHKLPLVTVVQNNAWAISVPFKDQCSTDLVRLGESYQGLSVYEVDGGDYFKLVDTFSKAVDQARHTSVPALI
LVDVMRLEPHSNSDNHEKYRSREDLDHCKSHDPLIRLERLMIDECGISPAEILDIKAEAEAEVTRACEIAEGMPFPSKGS
TSHDVFSPHTTSLIDYENSLEAQRLRDTQPKVMRDAITEALIEEMSRDSGVVVFGEDVAGDKGGVFGVTRNLTDRFGSER
CFNTPLAEATIIGTAIGMAMDGIHKPVAEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAPCGGYIQGGPYHSQ
SIEAFLAHCPGIKVAYPSNAADAKALLKAAIRDPNPVVFLEHKALYQRRIFSACPVFSSDYVLPFGKAAITQVGSDLTIV
SWGMSLVMSMEVAKELAALDISAEVIDLRTIVPCDFSTVIESVKKTSKLLIAHEASEFCGFGAELAATVAEQAYAYLDAP
IRRVAGLHAPVPYSKILENEVLPQKEKIFQAAKSLAEF

Sequences:

>Translated_678_residues
MVAIQHELGSSIKEVLKLVWSLRFAENKMLLLSRQSDSGGTFQLSCAGHELVGVVAGKSLLRGKDWSFPYYRDQGFPVGL
GCDLSEIFASFLGRLAPNHSSGRMMPYHYSHKKLRICCQSSVVGSQFLQAAGRAWAVKHTKSNEVVYVSGGDGSTSQGEF
HEMLNYVALHKLPLVTVVQNNAWAISVPFKDQCSTDLVRLGESYQGLSVYEVDGGDYFKLVDTFSKAVDQARHTSVPALI
LVDVMRLEPHSNSDNHEKYRSREDLDHCKSHDPLIRLERLMIDECGISPAEILDIKAEAEAEVTRACEIAEGMPFPSKGS
TSHDVFSPHTTSLIDYENSLEAQRLRDTQPKVMRDAITEALIEEMSRDSGVVVFGEDVAGDKGGVFGVTRNLTDRFGSER
CFNTPLAEATIIGTAIGMAMDGIHKPVAEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAPCGGYIQGGPYHSQ
SIEAFLAHCPGIKVAYPSNAADAKALLKAAIRDPNPVVFLEHKALYQRRIFSACPVFSSDYVLPFGKAAITQVGSDLTIV
SWGMSLVMSMEVAKELAALDISAEVIDLRTIVPCDFSTVIESVKKTSKLLIAHEASEFCGFGAELAATVAEQAYAYLDAP
IRRVAGLHAPVPYSKILENEVLPQKEKIFQAAKSLAEF
>Mature_678_residues
MVAIQHELGSSIKEVLKLVWSLRFAENKMLLLSRQSDSGGTFQLSCAGHELVGVVAGKSLLRGKDWSFPYYRDQGFPVGL
GCDLSEIFASFLGRLAPNHSSGRMMPYHYSHKKLRICCQSSVVGSQFLQAAGRAWAVKHTKSNEVVYVSGGDGSTSQGEF
HEMLNYVALHKLPLVTVVQNNAWAISVPFKDQCSTDLVRLGESYQGLSVYEVDGGDYFKLVDTFSKAVDQARHTSVPALI
LVDVMRLEPHSNSDNHEKYRSREDLDHCKSHDPLIRLERLMIDECGISPAEILDIKAEAEAEVTRACEIAEGMPFPSKGS
TSHDVFSPHTTSLIDYENSLEAQRLRDTQPKVMRDAITEALIEEMSRDSGVVVFGEDVAGDKGGVFGVTRNLTDRFGSER
CFNTPLAEATIIGTAIGMAMDGIHKPVAEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAPCGGYIQGGPYHSQ
SIEAFLAHCPGIKVAYPSNAADAKALLKAAIRDPNPVVFLEHKALYQRRIFSACPVFSSDYVLPFGKAAITQVGSDLTIV
SWGMSLVMSMEVAKELAALDISAEVIDLRTIVPCDFSTVIESVKKTSKLLIAHEASEFCGFGAELAATVAEQAYAYLDAP
IRRVAGLHAPVPYSKILENEVLPQKEKIFQAAKSLAEF

Specific function: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components:branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltran

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=372, Percent_Identity=40.8602150537634, Blast_Score=255, Evalue=9e-68,
Organism=Homo sapiens, GI34101272, Length=372, Percent_Identity=40.8602150537634, Blast_Score=255, Evalue=9e-68,
Organism=Homo sapiens, GI156564403, Length=344, Percent_Identity=38.0813953488372, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI291084858, Length=344, Percent_Identity=36.046511627907, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI258645172, Length=331, Percent_Identity=28.3987915407855, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI11386135, Length=332, Percent_Identity=28.3132530120482, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI4885543, Length=319, Percent_Identity=27.8996865203762, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI4505685, Length=315, Percent_Identity=27.9365079365079, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI291084742, Length=315, Percent_Identity=27.9365079365079, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI291084744, Length=278, Percent_Identity=28.0575539568345, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI291084757, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538422, Length=335, Percent_Identity=40.5970149253731, Blast_Score=250, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17506935, Length=355, Percent_Identity=41.6901408450704, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI86563357, Length=300, Percent_Identity=27.6666666666667, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI86563355, Length=300, Percent_Identity=27.6666666666667, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564172, Length=303, Percent_Identity=26.7326732673267, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536047, Length=303, Percent_Identity=26.7326732673267, Blast_Score=86, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319698, Length=358, Percent_Identity=37.4301675977654, Blast_Score=233, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6321026, Length=253, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI160714832, Length=328, Percent_Identity=41.7682926829268, Blast_Score=246, Evalue=5e-65,
Organism=Drosophila melanogaster, GI160714828, Length=328, Percent_Identity=41.7682926829268, Blast_Score=246, Evalue=5e-65,
Organism=Drosophila melanogaster, GI21358145, Length=349, Percent_Identity=39.2550143266476, Blast_Score=236, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24650940, Length=349, Percent_Identity=39.2550143266476, Blast_Score=236, Evalue=6e-62,
Organism=Drosophila melanogaster, GI21355903, Length=334, Percent_Identity=23.9520958083832, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639746, Length=259, Percent_Identity=25.4826254826255, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639740, Length=259, Percent_Identity=25.4826254826255, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639744, Length=259, Percent_Identity=25.4826254826255, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571106, Length=259, Percent_Identity=25.4826254826255, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639748, Length=267, Percent_Identity=28.8389513108614, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.4 [H]

Molecular weight: Translated: 74334; Mature: 74334

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAIQHELGSSIKEVLKLVWSLRFAENKMLLLSRQSDSGGTFQLSCAGHELVGVVAGKSL
CEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHH
LRGKDWSFPYYRDQGFPVGLGCDLSEIFASFLGRLAPNHSSGRMMPYHYSHKKLRICCQS
HCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCEEHHHHH
SVVGSQFLQAAGRAWAVKHTKSNEVVYVSGGDGSTSQGEFHEMLNYVALHKLPLVTVVQN
HHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEC
NAWAISVPFKDQCSTDLVRLGESYQGLSVYEVDGGDYFKLVDTFSKAVDQARHTSVPALI
CCEEEECCCCCCCCHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHH
LVDVMRLEPHSNSDNHEKYRSREDLDHCKSHDPLIRLERLMIDECGISPAEILDIKAEAE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHEEECCCHH
AEVTRACEIAEGMPFPSKGSTSHDVFSPHTTSLIDYENSLEAQRLRDTQPKVMRDAITEA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCHHHHHHHHHHH
LIEEMSRDSGVVVFGEDVAGDKGGVFGVTRNLTDRFGSERCFNTPLAEATIIGTAIGMAM
HHHHHCCCCCEEEECCCCCCCCCCEEEEEHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHH
DGIHKPVAEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAPCGGYIQGGPYHSQ
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEECCEEEECCCCCCCCCCCCCHH
SIEAFLAHCPGIKVAYPSNAADAKALLKAAIRDPNPVVFLEHKALYQRRIFSACPVFSSD
HHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCCC
YVLPFGKAAITQVGSDLTIVSWGMSLVMSMEVAKELAALDISAEVIDLRTIVPCDFSTVI
CCCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCHHHHH
ESVKKTSKLLIAHEASEFCGFGAELAATVAEQAYAYLDAPIRRVAGLHAPVPYSKILENE
HHHHHHHHEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLPQKEKIFQAAKSLAEF
CCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVAIQHELGSSIKEVLKLVWSLRFAENKMLLLSRQSDSGGTFQLSCAGHELVGVVAGKSL
CEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHH
LRGKDWSFPYYRDQGFPVGLGCDLSEIFASFLGRLAPNHSSGRMMPYHYSHKKLRICCQS
HCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCEEHHHHH
SVVGSQFLQAAGRAWAVKHTKSNEVVYVSGGDGSTSQGEFHEMLNYVALHKLPLVTVVQN
HHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEC
NAWAISVPFKDQCSTDLVRLGESYQGLSVYEVDGGDYFKLVDTFSKAVDQARHTSVPALI
CCEEEECCCCCCCCHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHH
LVDVMRLEPHSNSDNHEKYRSREDLDHCKSHDPLIRLERLMIDECGISPAEILDIKAEAE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHEEECCCHH
AEVTRACEIAEGMPFPSKGSTSHDVFSPHTTSLIDYENSLEAQRLRDTQPKVMRDAITEA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCHHHHHHHHHHH
LIEEMSRDSGVVVFGEDVAGDKGGVFGVTRNLTDRFGSERCFNTPLAEATIIGTAIGMAM
HHHHHCCCCCEEEECCCCCCCCCCEEEEEHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHH
DGIHKPVAEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAPCGGYIQGGPYHSQ
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEECCEEEECCCCCCCCCCCCCHH
SIEAFLAHCPGIKVAYPSNAADAKALLKAAIRDPNPVVFLEHKALYQRRIFSACPVFSSD
HHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHCCCCCCC
YVLPFGKAAITQVGSDLTIVSWGMSLVMSMEVAKELAALDISAEVIDLRTIVPCDFSTVI
CCCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCHHHHH
ESVKKTSKLLIAHEASEFCGFGAELAATVAEQAYAYLDAPIRRVAGLHAPVPYSKILENE
HHHHHHHHEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLPQKEKIFQAAKSLAEF
CCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8504804; 8969508; 9384377 [H]