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The map label for this gene is hflX [H]

Identifier: 62184900

GI number: 62184900

Start: 283420

End: 284808

Strand: Direct

Name: hflX [H]

Synonym: CAB259

Alternate gene names: 62184900

Gene position: 283420-284808 (Clockwise)

Preceding gene: 62184899

Following gene: 62184901

Centisome position: 24.77

GC content: 42.04

Gene sequence:

>1389_bases
GTGAAAAAAAAGAGAAAAGAAGAGAAAAAGAGTCGAGAGAGTGCTTTAGGATGGCGTTTTTCTCTTCCTCGTGAAGAGCA
AGATCCTTCCCAAGCTTTGGCGGTTTCTTGTTATTCAGGGAAAGAGGACCAACGGCGTGTGGAAGAACATAGTGAAGAGC
TAGTTTCTCTTGCAGAATCTTGTGAGATTACCGTGTTAGAAACACGTTCATGGATTTTGCGATCTCCTTCTTCTTCGACA
TATTTAAATGAAGGCAAGCTTTTAGAAATCGAAGAGGTTTTAAAAGTATTTCCTACGATAGGTGCCTTGATTATTGATGA
AGAAATCACCGCTTCACAGCAGAGGAATTTAGAAAAGCGTTTAGGCGTCGTGGTTTTAGATCGTACGGAGTTAATCTTAG
AGATTTTTGCTAACCGAGCTTTTACTGCAGAAGCAGGACTTCAGGTAGAATTAGCACGCGCACGCTACCTGCTCCCTCGT
TTAAAAAGGATGTGGGGTCACCTATCACGTCAAAAATCCGGAGGTGGCAGTGGCGGAGGATTTGTTAAGGGCGAAGGGGA
GAAGCAAATCGAACTAGATAGAAGGATGATTCGTGAAAGAATTCACAAATTAACTTTGGATCTTAAATCCGTAGAAAAGC
AAAGAAAAGAGCAGCGCAAGGCTAAAGAAAAACGGGGCATTCCTTCGTTTGCTTTGATTGGTTATACCAATTCTGGGAAA
AGTACTTTGTTGAATCTTTTAACTTCTGCGGAAACTTACGTTGAGGACAAACTTTTTGCGACTTTAGATCCGAAAACACG
TAGGTGTGTTCTTCCTAGTGGGCAACGTGTTCTTGTTACAGATACCGTAGGGTTTATCCGGAAATTGCCCCATACTCTTG
TGGCAGCATTTAAAAGTACCTTAGAAGCTGCGTTACATGAGGATGTTTTACTTCATGTTGTGGACGCTTCGCATCCCTTA
GCTTTTGAGCATATAGAAACCACACAAGAGATCTTAAAAGAATTAGGAGTCGACCATCCGAAAATCATCACAGTGTTAAA
TAAGATCGATGAGCTTCCCGAGGGTAAGGCGCCTACCAAGTTGCGTTTGCTCTCACCACGTGCTGTCGTCATCTCGGCAA
AAACCGGAGAGGGAATTCAAAATCTTCTTGAGGCGATGACTGACATCATTACGGAAGGCTTTCCTCAAGTTACATTAAAA
TTTTCCTATAAGGATTATGGCAAATTTACCGAGCTGTATGATGCAGGTTTGGTCTTAGCGCATCGTCGTAAAGAGGATAT
TTTAATTGTAGACGCTTATCTACCCGAAGAGCTCGGGAAAAAATACCAACAGTTTATTATGCGTAAACGTCCTTCTCCAA
AGCCCATAGAAGATGAGTTTTGCGTTTAG

Upstream 100 bases:

>100_bases
GCATATCAATCATAGCTTACAAAAAGAGTTGGCAAATTATTCCGATAAGTTGTGGGCTTATGACGGTATGGAAGTTTCTT
GGTCGTTCGTTAGGTAGACA

Downstream 100 bases:

>100_bases
GGAGTTCCTTTACAAGCGAATAAGAAAAAAGAGAATCTTTATTAGTGAGGAAAAGTAGGGATACTTTAGAATACTGTCTT
TGTGTTTTTTCAGATTTCAT

Product: putative GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MKKKRKEEKKSRESALGWRFSLPREEQDPSQALAVSCYSGKEDQRRVEEHSEELVSLAESCEITVLETRSWILRSPSSST
YLNEGKLLEIEEVLKVFPTIGALIIDEEITASQQRNLEKRLGVVVLDRTELILEIFANRAFTAEAGLQVELARARYLLPR
LKRMWGHLSRQKSGGGSGGGFVKGEGEKQIELDRRMIRERIHKLTLDLKSVEKQRKEQRKAKEKRGIPSFALIGYTNSGK
STLLNLLTSAETYVEDKLFATLDPKTRRCVLPSGQRVLVTDTVGFIRKLPHTLVAAFKSTLEAALHEDVLLHVVDASHPL
AFEHIETTQEILKELGVDHPKIITVLNKIDELPEGKAPTKLRLLSPRAVVISAKTGEGIQNLLEAMTDIITEGFPQVTLK
FSYKDYGKFTELYDAGLVLAHRRKEDILIVDAYLPEELGKKYQQFIMRKRPSPKPIEDEFCV

Sequences:

>Translated_462_residues
MKKKRKEEKKSRESALGWRFSLPREEQDPSQALAVSCYSGKEDQRRVEEHSEELVSLAESCEITVLETRSWILRSPSSST
YLNEGKLLEIEEVLKVFPTIGALIIDEEITASQQRNLEKRLGVVVLDRTELILEIFANRAFTAEAGLQVELARARYLLPR
LKRMWGHLSRQKSGGGSGGGFVKGEGEKQIELDRRMIRERIHKLTLDLKSVEKQRKEQRKAKEKRGIPSFALIGYTNSGK
STLLNLLTSAETYVEDKLFATLDPKTRRCVLPSGQRVLVTDTVGFIRKLPHTLVAAFKSTLEAALHEDVLLHVVDASHPL
AFEHIETTQEILKELGVDHPKIITVLNKIDELPEGKAPTKLRLLSPRAVVISAKTGEGIQNLLEAMTDIITEGFPQVTLK
FSYKDYGKFTELYDAGLVLAHRRKEDILIVDAYLPEELGKKYQQFIMRKRPSPKPIEDEFCV
>Mature_462_residues
MKKKRKEEKKSRESALGWRFSLPREEQDPSQALAVSCYSGKEDQRRVEEHSEELVSLAESCEITVLETRSWILRSPSSST
YLNEGKLLEIEEVLKVFPTIGALIIDEEITASQQRNLEKRLGVVVLDRTELILEIFANRAFTAEAGLQVELARARYLLPR
LKRMWGHLSRQKSGGGSGGGFVKGEGEKQIELDRRMIRERIHKLTLDLKSVEKQRKEQRKAKEKRGIPSFALIGYTNSGK
STLLNLLTSAETYVEDKLFATLDPKTRRCVLPSGQRVLVTDTVGFIRKLPHTLVAAFKSTLEAALHEDVLLHVVDASHPL
AFEHIETTQEILKELGVDHPKIITVLNKIDELPEGKAPTKLRLLSPRAVVISAKTGEGIQNLLEAMTDIITEGFPQVTLK
FSYKDYGKFTELYDAGLVLAHRRKEDILIVDAYLPEELGKKYQQFIMRKRPSPKPIEDEFCV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=226, Percent_Identity=37.6106194690265, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI310133118, Length=226, Percent_Identity=37.6106194690265, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI310124269, Length=203, Percent_Identity=38.423645320197, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI310124267, Length=203, Percent_Identity=38.423645320197, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI310124171, Length=203, Percent_Identity=38.423645320197, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI310124169, Length=203, Percent_Identity=38.423645320197, Blast_Score=129, Evalue=6e-30,
Organism=Escherichia coli, GI1790615, Length=373, Percent_Identity=41.0187667560322, Blast_Score=252, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI17561038, Length=359, Percent_Identity=30.6406685236769, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24650079, Length=293, Percent_Identity=30.7167235494881, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52351; Mature: 52351

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKRKEEKKSRESALGWRFSLPREEQDPSQALAVSCYSGKEDQRRVEEHSEELVSLAES
CCCHHHHHHHHHHHHCCEEECCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHC
CEITVLETRSWILRSPSSSTYLNEGKLLEIEEVLKVFPTIGALIIDEEITASQQRNLEKR
CCEEEEECCHHHEECCCCCCCCCCCCEECHHHHHHHHHHHHHEEECCHHHHHHHHCHHHH
LGVVVLDRTELILEIFANRAFTAEAGLQVELARARYLLPRLKRMWGHLSRQKSGGGSGGG
CCEEEECHHHHHHHHHHCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FVKGEGEKQIELDRRMIRERIHKLTLDLKSVEKQRKEQRKAKEKRGIPSFALIGYTNSGK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCH
STLLNLLTSAETYVEDKLFATLDPKTRRCVLPSGQRVLVTDTVGFIRKLPHTLVAAFKST
HHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
LEAALHEDVLLHVVDASHPLAFEHIETTQEILKELGVDHPKIITVLNKIDELPEGKAPTK
HHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCE
LRLLSPRAVVISAKTGEGIQNLLEAMTDIITEGFPQVTLKFSYKDYGKFTELYDAGLVLA
EEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCHHEE
HRRKEDILIVDAYLPEELGKKYQQFIMRKRPSPKPIEDEFCV
ECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKKRKEEKKSRESALGWRFSLPREEQDPSQALAVSCYSGKEDQRRVEEHSEELVSLAES
CCCHHHHHHHHHHHHCCEEECCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHC
CEITVLETRSWILRSPSSSTYLNEGKLLEIEEVLKVFPTIGALIIDEEITASQQRNLEKR
CCEEEEECCHHHEECCCCCCCCCCCCEECHHHHHHHHHHHHHEEECCHHHHHHHHCHHHH
LGVVVLDRTELILEIFANRAFTAEAGLQVELARARYLLPRLKRMWGHLSRQKSGGGSGGG
CCEEEECHHHHHHHHHHCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FVKGEGEKQIELDRRMIRERIHKLTLDLKSVEKQRKEQRKAKEKRGIPSFALIGYTNSGK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCH
STLLNLLTSAETYVEDKLFATLDPKTRRCVLPSGQRVLVTDTVGFIRKLPHTLVAAFKST
HHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
LEAALHEDVLLHVVDASHPLAFEHIETTQEILKELGVDHPKIITVLNKIDELPEGKAPTK
HHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCE
LRLLSPRAVVISAKTGEGIQNLLEAMTDIITEGFPQVTLKFSYKDYGKFTELYDAGLVLA
EEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCHHEE
HRRKEDILIVDAYLPEELGKKYQQFIMRKRPSPKPIEDEFCV
ECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]