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The map label for this gene is dppB [H]

Identifier: 62184786

GI number: 62184786

Start: 150758

End: 152227

Strand: Direct

Name: dppB [H]

Synonym: CAB141

Alternate gene names: 62184786

Gene position: 150758-152227 (Clockwise)

Preceding gene: 62184785

Following gene: 62184787

Centisome position: 13.17

GC content: 39.8

Gene sequence:

>1470_bases
GTGCTTAAGTATATCTTAAAACGTCTGATATTAATTCCTCTGACGCTGTTTGCCATTATTTCCATTAATTTCATTATATT
GAACGCAGCTCCAGGAGATGTTATCGAAGAGCAATCCGTGGATGCCTTTGGAGATCCAGGGAAGTCGGATAAGATCCGTA
CATACAAAGGTCCTGATCGCTATTTACAGTTTCGCGAGCATTATGGCTTAACTCTACCCATTTTTTTTAATACGCGTCCT
GCAATTTCACACGCTAAAGTCAAGAGCGGGATAGAAGAAATCGTCGATTGCTTCATCAAGAAGCAATCTTTTTCTAAATT
AAAGATTTATTGGGGTGATAGGGCAAAATTTCTTCTGCCCGTATTATTATTTGAAGCTAACGACAATACAAAAACACCTT
CCTATCGTCATGTTGCCGCAGACTTATTCATTCGTGGAGCTATCCGTCAGGGAATAGTTGGCTCAGGCCTATCCCCAGAA
CAATATGCGTATAATGAAAGAGTTTCCAAAAGCAATGCTATGCTTGTGAAGCTTCTTTCTGAAGAAGATATTGGGATTAA
GGTAGATTCTTTAAAGGAATGGTTTCGTCAGGAAGGAGGTATGGAAGCCTTTCCCTATAGACACTTTTCTTGGAAGACCT
TTTTTTTAGAAACACGTTTTGCTCGCTATATGTCGCGTGTTTTACGTTTGGATTTCGGAACCTTACGTAATGATCCACAT
AAAACGGTAGTTTCTGAAGTGGTTAAACGTTTGCGTTCTTCGTTAACGCTATCAGTTTTCCCTATGATCCTAGTGTTTAT
CTTATGTCAAGTATTTGGCATGCTTATGGCGTTAAATAGAAACCGTTGGATCGATCATACACTGAATTTTATCTTCCTGT
TTCTATTCTCTGTTCCTGTCTTTGTGGCTGTTCCTTGGATTATTGATAATTTCGTAATTAATAAAACCATCCCATTTACC
TCTATTCCTATGCCATACAGCGGCTTACAATCCTCTCCGGAAATTTTCAATCAGTTGAGTTCTTGGGGGAAGATTTTAGA
TACCTTAGCTCATAGCTTTCTTCCTTTTTGTGCTGTAAGTTATGGGGCATTTGCTTCTCAGTCACGGTTAAGTAGATCGG
TCTTTTTAGAAATCCTAGGAGAAGACTATATTTGTGCCGCACGAGCTCGTGGTGTGTCTCGTTATGATATTCTTGTCAAG
CACGTAGGGAAGAACGCAGCTTCTTCCTTGATTACTTCACTAGCTTCGTCTTTAGGCGCTATATTGGGAGGGGCTTTAGT
TGTAGAAACCCTGTTTGATATCGATGGGTTTGGGAGATTTTTCTATCAGGCCATTTTAAATCGAGATCATAATGTGGTGT
TGTTTTCTGTCCTCGTTGGATCCGCTCTATCCCTATTAGGTTATTTAATAGGGGATATTTGCTACGTGCTATTAGATCCG
AGGGTACAACTAGGAGGTAAGAGGGTTTAA

Upstream 100 bases:

>100_bases
AAAACGTCTTTGTCCCCAAACAGAGAACAGATTTAATTCCTGACGCTCAAGACGAAATGGTGAATCTTCATATGGTTTGG
TTAGACAGGAAGGAGGAAGA

Downstream 100 bases:

>100_bases
AATGGAATCCCCGACTTCTTTTTATCGCCGATTCTTTCAGGCATACCATAAGAATTTCCTTGCCTCTCTGTCATGGAAGT
TTGTTATCGCATTAGTACTT

Product: putative transport protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MLKYILKRLILIPLTLFAIISINFIILNAAPGDVIEEQSVDAFGDPGKSDKIRTYKGPDRYLQFREHYGLTLPIFFNTRP
AISHAKVKSGIEEIVDCFIKKQSFSKLKIYWGDRAKFLLPVLLFEANDNTKTPSYRHVAADLFIRGAIRQGIVGSGLSPE
QYAYNERVSKSNAMLVKLLSEEDIGIKVDSLKEWFRQEGGMEAFPYRHFSWKTFFLETRFARYMSRVLRLDFGTLRNDPH
KTVVSEVVKRLRSSLTLSVFPMILVFILCQVFGMLMALNRNRWIDHTLNFIFLFLFSVPVFVAVPWIIDNFVINKTIPFT
SIPMPYSGLQSSPEIFNQLSSWGKILDTLAHSFLPFCAVSYGAFASQSRLSRSVFLEILGEDYICAARARGVSRYDILVK
HVGKNAASSLITSLASSLGAILGGALVVETLFDIDGFGRFFYQAILNRDHNVVLFSVLVGSALSLLGYLIGDICYVLLDP
RVQLGGKRV

Sequences:

>Translated_489_residues
MLKYILKRLILIPLTLFAIISINFIILNAAPGDVIEEQSVDAFGDPGKSDKIRTYKGPDRYLQFREHYGLTLPIFFNTRP
AISHAKVKSGIEEIVDCFIKKQSFSKLKIYWGDRAKFLLPVLLFEANDNTKTPSYRHVAADLFIRGAIRQGIVGSGLSPE
QYAYNERVSKSNAMLVKLLSEEDIGIKVDSLKEWFRQEGGMEAFPYRHFSWKTFFLETRFARYMSRVLRLDFGTLRNDPH
KTVVSEVVKRLRSSLTLSVFPMILVFILCQVFGMLMALNRNRWIDHTLNFIFLFLFSVPVFVAVPWIIDNFVINKTIPFT
SIPMPYSGLQSSPEIFNQLSSWGKILDTLAHSFLPFCAVSYGAFASQSRLSRSVFLEILGEDYICAARARGVSRYDILVK
HVGKNAASSLITSLASSLGAILGGALVVETLFDIDGFGRFFYQAILNRDHNVVLFSVLVGSALSLLGYLIGDICYVLLDP
RVQLGGKRV
>Mature_489_residues
MLKYILKRLILIPLTLFAIISINFIILNAAPGDVIEEQSVDAFGDPGKSDKIRTYKGPDRYLQFREHYGLTLPIFFNTRP
AISHAKVKSGIEEIVDCFIKKQSFSKLKIYWGDRAKFLLPVLLFEANDNTKTPSYRHVAADLFIRGAIRQGIVGSGLSPE
QYAYNERVSKSNAMLVKLLSEEDIGIKVDSLKEWFRQEGGMEAFPYRHFSWKTFFLETRFARYMSRVLRLDFGTLRNDPH
KTVVSEVVKRLRSSLTLSVFPMILVFILCQVFGMLMALNRNRWIDHTLNFIFLFLFSVPVFVAVPWIIDNFVINKTIPFT
SIPMPYSGLQSSPEIFNQLSSWGKILDTLAHSFLPFCAVSYGAFASQSRLSRSVFLEILGEDYICAARARGVSRYDILVK
HVGKNAASSLITSLASSLGAILGGALVVETLFDIDGFGRFFYQAILNRDHNVVLFSVLVGSALSLLGYLIGDICYVLLDP
RVQLGGKRV

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=282, Percent_Identity=28.3687943262411, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788504, Length=275, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1787053, Length=291, Percent_Identity=27.1477663230241, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789888, Length=269, Percent_Identity=25.2788104089219, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787497, Length=269, Percent_Identity=26.7657992565056, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=24.9084249084249, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787761, Length=316, Percent_Identity=27.5316455696203, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55214; Mature: 55214

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYILKRLILIPLTLFAIISINFIILNAAPGDVIEEQSVDAFGDPGKSDKIRTYKGPDR
CHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
YLQFREHYGLTLPIFFNTRPAISHAKVKSGIEEIVDCFIKKQSFSKLKIYWGDRAKFLLP
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
VLLFEANDNTKTPSYRHVAADLFIRGAIRQGIVGSGLSPEQYAYNERVSKSNAMLVKLLS
HHEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHEEEC
EEDIGIKVDSLKEWFRQEGGMEAFPYRHFSWKTFFLETRFARYMSRVLRLDFGTLRNDPH
CCCCCEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KTVVSEVVKRLRSSLTLSVFPMILVFILCQVFGMLMALNRNRWIDHTLNFIFLFLFSVPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FVAVPWIIDNFVINKTIPFTSIPMPYSGLQSSPEIFNQLSSWGKILDTLAHSFLPFCAVS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGAFASQSRLSRSVFLEILGEDYICAARARGVSRYDILVKHVGKNAASSLITSLASSLGA
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ILGGALVVETLFDIDGFGRFFYQAILNRDHNVVLFSVLVGSALSLLGYLIGDICYVLLDP
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
RVQLGGKRV
HHHCCCCCC
>Mature Secondary Structure
MLKYILKRLILIPLTLFAIISINFIILNAAPGDVIEEQSVDAFGDPGKSDKIRTYKGPDR
CHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
YLQFREHYGLTLPIFFNTRPAISHAKVKSGIEEIVDCFIKKQSFSKLKIYWGDRAKFLLP
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
VLLFEANDNTKTPSYRHVAADLFIRGAIRQGIVGSGLSPEQYAYNERVSKSNAMLVKLLS
HHEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHEEEC
EEDIGIKVDSLKEWFRQEGGMEAFPYRHFSWKTFFLETRFARYMSRVLRLDFGTLRNDPH
CCCCCEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KTVVSEVVKRLRSSLTLSVFPMILVFILCQVFGMLMALNRNRWIDHTLNFIFLFLFSVPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FVAVPWIIDNFVINKTIPFTSIPMPYSGLQSSPEIFNQLSSWGKILDTLAHSFLPFCAVS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGAFASQSRLSRSVFLEILGEDYICAARARGVSRYDILVKHVGKNAASSLITSLASSLGA
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ILGGALVVETLFDIDGFGRFFYQAILNRDHNVVLFSVLVGSALSLLGYLIGDICYVLLDP
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
RVQLGGKRV
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]