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The map label for this gene is fabZ

Identifier: 62184733

GI number: 62184733

Start: 104682

End: 105146

Strand: Direct

Name: fabZ

Synonym: CAB089

Alternate gene names: 62184733

Gene position: 104682-105146 (Clockwise)

Preceding gene: 62184732

Following gene: 62184734

Centisome position: 9.15

GC content: 41.94

Gene sequence:

>465_bases
ATGAAAGAGTCGCCTGTAATTAAATTACGAGAATTATTAAACTTACTCCCGCATCGTTATCCTTTTTTGCTTGTGGATAA
GGTGTTGTCTTATGATTTAGAGAGACGGTCCATTGTTGCACAAAAAAATGTAACAATAAACGAGCCTTTTTTTGTAGGGC
ATTTCCCCGAAGCACCTATCATGCCTGGAGTGTTAATATTAGAATCTTTAGCGCAAGCAGCCGGAGTTTTGCTGGGCTTA
GTTTTAGAAAATGACAGAAATAAACGACTGGCTTTGTTTTTGGGGATACACAAAGCAAAGTTTCGCCAGGCAGTTAAGCC
CGGCGACATTCTTACATTGAGCGCTGAATTTTCATTGATTTCGTCGAAGGGAGGGAAAGCTTCGGCTCGGGCTTGTGTGG
GTTCCCAGGTTGCGGCTGAGGGAGAACTAAGCTTTGCTCTTGTAGACAAGAAATCTTTAGATTAA

Upstream 100 bases:

>100_bases
TTGTTGCTCATATTGTGGCTGTGGGGTCGGGACATTCTTCAAACATTGCTTTGGGTAGAAAGATTTTAGAAGTGTTACAA
CCCTAAGAAACGAGTGCTAA

Downstream 100 bases:

>100_bases
CGGAGACGTATGACGAACATTCACCCAACAGCAATTATCGAACCCGGGGCTAAAATCGGAAGGAATGTTGTTATTGAGCC
GTATGTTGTTATTAAATCTA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKESPVIKLRELLNLLPHRYPFLLVDKVLSYDLERRSIVAQKNVTINEPFFVGHFPEAPIMPGVLILESLAQAAGVLLGL
VLENDRNKRLALFLGIHKAKFRQAVKPGDILTLSAEFSLISSKGGKASARACVGSQVAAEGELSFALVDKKSLD

Sequences:

>Translated_154_residues
MKESPVIKLRELLNLLPHRYPFLLVDKVLSYDLERRSIVAQKNVTINEPFFVGHFPEAPIMPGVLILESLAQAAGVLLGL
VLENDRNKRLALFLGIHKAKFRQAVKPGDILTLSAEFSLISSKGGKASARACVGSQVAAEGELSFALVDKKSLD
>Mature_154_residues
MKESPVIKLRELLNLLPHRYPFLLVDKVLSYDLERRSIVAQKNVTINEPFFVGHFPEAPIMPGVLILESLAQAAGVLLGL
VLENDRNKRLALFLGIHKAKFRQAVKPGDILTLSAEFSLISSKGGKASARACVGSQVAAEGELSFALVDKKSLD

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=141, Percent_Identity=42.5531914893617, Blast_Score=112, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_CHLAB (Q5L724)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_219518.1
- ProteinModelPortal:   Q5L724
- SMR:   Q5L724
- GeneID:   3338042
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB089
- HOGENOM:   HBG433282
- OMA:   KASARAC
- ProtClustDB:   PRK00006
- BioCyc:   CABO218497:CAB089-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16835; Mature: 16835

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESPVIKLRELLNLLPHRYPFLLVDKVLSYDLERRSIVAQKNVTINEPFFVGHFPEAPI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCCEECCCEEEECCCCCCC
MPGVLILESLAQAAGVLLGLVLENDRNKRLALFLGIHKAKFRQAVKPGDILTLSAEFSLI
CCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEHHHHHHHHHCCCCCEEEEEECEEEE
SSKGGKASARACVGSQVAAEGELSFALVDKKSLD
ECCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MKESPVIKLRELLNLLPHRYPFLLVDKVLSYDLERRSIVAQKNVTINEPFFVGHFPEAPI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCCEECCCEEEECCCCCCC
MPGVLILESLAQAAGVLLGLVLENDRNKRLALFLGIHKAKFRQAVKPGDILTLSAEFSLI
CCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEHHHHHHHHHCCCCCEEEEEECEEEE
SSKGGKASARACVGSQVAAEGELSFALVDKKSLD
ECCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA