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The map label for this gene is pitA [C]

Identifier: 62184708

GI number: 62184708

Start: 74686

End: 75966

Strand: Direct

Name: pitA [C]

Synonym: CAB061

Alternate gene names: 62184708

Gene position: 74686-75966 (Clockwise)

Preceding gene: 62184707

Following gene: 62184709

Centisome position: 6.53

GC content: 42.0

Gene sequence:

>1281_bases
ATGCTTGCCTTACTCATTTTTGTTCTCTTATGTGGTTTCTATACCTCTTGGAATATAGGAGCTAACGACGTTGCCAATGC
TGTTGGCCCCAGTGTAGGATCCGGAGTATTAACACTACGACAAGCTGTAGTCATTGCCGCGATTTTTGAATTTTTAGGGG
CATTATTTCTAGGAGATCGTGTCGCAGGAACTATAGAAAGCCATATTGTTTCTGTTTCAGATCCTTTAATGGCTTCCGGG
GATTACGTTTATGGTATGACAGGAGCCTTGTTAGCTACAGGAGTTTGGCTCCAATTGGCCTCTTATTTTGGATGGCCAGT
CTCTACAACCCATTCTATAGTTGGAGCGGTAATCGGCTTTGGTCTTGTTCTCGGTAAAGGCACAGTGATTTACTGGGGAT
CTATAGGGGCAATTTTAGTTAGCTGGGTAATCTCTCCATTAATGGGGGGATGCATTGCGTATGCCATCTTCTCTTTTATA
CGTAGGAATATTCTTTATAAGAATGACCCTGTCGGAGCAATGATTCGCATAGCGCCTTTTCTTGCTGCTTTTGTCATCAT
CGTTTTAGGGATTATTATTGTTTGCGGAGGGATAGTCACCCGGTTGATTCCTTTACCTTGGGCGTTGGCATCAGTATTCT
TAGTCGGGAGTATGGCTTATGCTATTATGTTTAAATATGTGCATACGCCGCATTGCTCTTTTATTTCTCCTTCGCCTAAA
TCAGGGAGTTTGCTTTGTCGTTTAAAAACATGCGGGGGAAACTATGGTAGAAAGTATCTTATCGTAGAAAGAATCTTTGC
GTACTTACAAATTATTATCACATGTTTTATGGCTTTTGCTCACGGATCTAATGACGTTGCGAATGCCATAGCTCCGGTTG
CTGGAGTTCTACGACACGTCTATCCCCATGTATATTCTTCCTATACGCTAATAGGTCTTATGGCGTTTGGGGGCGTGGGA
TTGATTATAGGGTTATCTATTTGGGGATGGCGCGTCATCGAAACCGTAGGATGTAAGATTACAGAACTCACACCTTCAAG
AGGTTTTTCTGTGGGGTTAAGTTCAGCTGTTACGATTGCTTTAGCTTCAGCTATAGGTTTACCCATATCGACAACTCATG
TCGTTGTCGGAGCTGTCTTAGGTATAGGCTTAGCTCGAGGTATCCATGCGATTAATTTAAATATCATTAAAGATATTATC
ATGTCGTGGTTTATCACTCTTCCAGCAGGAGCAATTCTCTCTATTCTATTTTTCTTTGCTTTAAGAGCGCTCTTCCAGTA
A

Upstream 100 bases:

>100_bases
TTTATGGCTGCAGGTAATTAAACGCGCAGCGGGCATATCCGATAGTGCGGAGAAGCTTGCTCATCGAGTTAACATGACGC
TGGAAGAAAAGTAGTATTTC

Downstream 100 bases:

>100_bases
AAATAGGGAAATCATCTTAGATAGTTTCTCAAGGTATATGGATAGATTGACAGTCAGGGAACTCTCCCCAGAAGAAAAAA
AGGTTTTAGTCCGTGTAGAT

Product: putative phosphate permease

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MLALLIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFLGALFLGDRVAGTIESHIVSVSDPLMASG
DYVYGMTGALLATGVWLQLASYFGWPVSTTHSIVGAVIGFGLVLGKGTVIYWGSIGAILVSWVISPLMGGCIAYAIFSFI
RRNILYKNDPVGAMIRIAPFLAAFVIIVLGIIIVCGGIVTRLIPLPWALASVFLVGSMAYAIMFKYVHTPHCSFISPSPK
SGSLLCRLKTCGGNYGRKYLIVERIFAYLQIIITCFMAFAHGSNDVANAIAPVAGVLRHVYPHVYSSYTLIGLMAFGGVG
LIIGLSIWGWRVIETVGCKITELTPSRGFSVGLSSAVTIALASAIGLPISTTHVVVGAVLGIGLARGIHAINLNIIKDII
MSWFITLPAGAILSILFFFALRALFQ

Sequences:

>Translated_426_residues
MLALLIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFLGALFLGDRVAGTIESHIVSVSDPLMASG
DYVYGMTGALLATGVWLQLASYFGWPVSTTHSIVGAVIGFGLVLGKGTVIYWGSIGAILVSWVISPLMGGCIAYAIFSFI
RRNILYKNDPVGAMIRIAPFLAAFVIIVLGIIIVCGGIVTRLIPLPWALASVFLVGSMAYAIMFKYVHTPHCSFISPSPK
SGSLLCRLKTCGGNYGRKYLIVERIFAYLQIIITCFMAFAHGSNDVANAIAPVAGVLRHVYPHVYSSYTLIGLMAFGGVG
LIIGLSIWGWRVIETVGCKITELTPSRGFSVGLSSAVTIALASAIGLPISTTHVVVGAVLGIGLARGIHAINLNIIKDII
MSWFITLPAGAILSILFFFALRALFQ
>Mature_426_residues
MLALLIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFLGALFLGDRVAGTIESHIVSVSDPLMASG
DYVYGMTGALLATGVWLQLASYFGWPVSTTHSIVGAVIGFGLVLGKGTVIYWGSIGAILVSWVISPLMGGCIAYAIFSFI
RRNILYKNDPVGAMIRIAPFLAAFVIIVLGIIIVCGGIVTRLIPLPWALASVFLVGSMAYAIMFKYVHTPHCSFISPSPK
SGSLLCRLKTCGGNYGRKYLIVERIFAYLQIIITCFMAFAHGSNDVANAIAPVAGVLRHVYPHVYSSYTLIGLMAFGGVG
LIIGLSIWGWRVIETVGCKITELTPSRGFSVGLSSAVTIALASAIGLPISTTHVVVGAVLGIGLARGIHAINLNIIKDII
MSWFITLPAGAILSILFFFALRALFQ

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=175, Percent_Identity=45.1428571428571, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI5803173, Length=156, Percent_Identity=42.3076923076923, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25146401, Length=457, Percent_Identity=32.8227571115974, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71981576, Length=432, Percent_Identity=32.6388888888889, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI32566716, Length=466, Percent_Identity=32.8326180257511, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17536725, Length=469, Percent_Identity=26.6524520255864, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17557328, Length=491, Percent_Identity=25.2545824847251, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17539280, Length=190, Percent_Identity=42.6315789473684, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319773, Length=159, Percent_Identity=37.7358490566038, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21356511, Length=195, Percent_Identity=39.4871794871795, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 45158; Mature: 45158

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALLIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFLGALFLGDR
CHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGTIESHIVSVSDPLMASGDYVYGMTGALLATGVWLQLASYFGWPVSTTHSIVGAVIGF
HHHHHHHHHEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLVLGKGTVIYWGSIGAILVSWVISPLMGGCIAYAIFSFIRRNILYKNDPVGAMIRIAPF
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAAFVIIVLGIIIVCGGIVTRLIPLPWALASVFLVGSMAYAIMFKYVHTPHCSFISPSPK
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SGSLLCRLKTCGGNYGRKYLIVERIFAYLQIIITCFMAFAHGSNDVANAIAPVAGVLRHV
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YPHVYSSYTLIGLMAFGGVGLIIGLSIWGWRVIETVGCKITELTPSRGFSVGLSSAVTIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHH
LASAIGLPISTTHVVVGAVLGIGLARGIHAINLNIIKDIIMSWFITLPAGAILSILFFFA
HHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LRALFQ
HHHHCC
>Mature Secondary Structure
MLALLIFVLLCGFYTSWNIGANDVANAVGPSVGSGVLTLRQAVVIAAIFEFLGALFLGDR
CHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGTIESHIVSVSDPLMASGDYVYGMTGALLATGVWLQLASYFGWPVSTTHSIVGAVIGF
HHHHHHHHHEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLVLGKGTVIYWGSIGAILVSWVISPLMGGCIAYAIFSFIRRNILYKNDPVGAMIRIAPF
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAAFVIIVLGIIIVCGGIVTRLIPLPWALASVFLVGSMAYAIMFKYVHTPHCSFISPSPK
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SGSLLCRLKTCGGNYGRKYLIVERIFAYLQIIITCFMAFAHGSNDVANAIAPVAGVLRHV
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YPHVYSSYTLIGLMAFGGVGLIIGLSIWGWRVIETVGCKITELTPSRGFSVGLSSAVTIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHH
LASAIGLPISTTHVVVGAVLGIGLARGIHAINLNIIKDIIMSWFITLPAGAILSILFFFA
HHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LRALFQ
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]