Click here to switch to the map view.

The map label for this gene is ycjZ [H]

Identifier: 59714331

GI number: 59714331

Start: 1290190

End: 1291152

Strand: Reverse

Name: ycjZ [H]

Synonym: VF_A1148

Alternate gene names: 59714331

Gene position: 1291152-1290190 (Counterclockwise)

Preceding gene: 59714332

Following gene: 59714330

Centisome position: 97.05

GC content: 40.39

Gene sequence:

>963_bases
ATGTCTCTGGTTAATCAACTTTCTCTATTTATCGATGTGGTGCAACAAGGCTCATTCACTAAAGCGGCCGCATTGCATGA
TATGGATAATTCTGCGCTTTCAAAACAGATCAAAAAATTAGAAGCAGAGCTAGGTGTTCAGTTACTTAACCGCTCGACTC
GTACTTTCTCATTAACACCAGCAGGCGAAGAGATCTTAGAGCAAGCGTATCAGTTAGTTGGCTCATTAGATAACGTGAAA
TCCATTGCAGACTCATATCAAGCAGTACCAAAAGGGCGAATTAGAATTACAGCTCCATTGCATATTGGGCAAGGGTATTT
ACAACCTGTTATTAGTCAGTTTATGACCACTTATCCAGATGTTGAGGTAGTTCTGATGATGGATGATAAGCGCTCCGATA
TCATTTCAGAGCACTTTGATGTCGCTTTTCGATTAGGTCGATTAGATGATTCAAGTTTGATAGCGAAAAAAGTGGCAGAT
ATTCGAGGGGTGATCCTCGCTTCACATTCACTTATTGAACGCTTTGGAGAGCCAAGTACACCAGAAGAATTGGTAAACTT
ACCCTCTGTTATTTACAGCAATGGCACATTAACGGTAGATACCGTTCGATTAGGTGAAAGCCCAGATTCATCTCAATTTA
AAAGCTATAAAATGAAAGGTAATTATAAGGTAAATGATGTTCGAACCTTATTGTCAGCCGTTCAAGATGGTTTAGGTTAT
GCCGTGGTGGCTTCATCAAACCTTGAGCGTTCTATCGAAAGCATGGGATTAACAACGTTACTTACGGATTACCCATTATG
TAATCAAGGCTTAGCAATATACGCACTTTATCCGCATCGAAAACAGACCGCATTGGTTAGAGAGTTCATTAGTGCCGTGC
AAAAGCATATTGGTCATCCTCCTCTTTGGGAGCAACATATCCCAAATTTTGCCTCTTTATATCCAGTAAAAAAGGGGCAG
TAG

Upstream 100 bases:

>100_bases
GAATAATTTTCGTATTCGCACTAAAATTAAGGTTTAATATCACAATGTATTTGGATTGGTTTCACTTTAAATCAAATCGA
CGGGTGTTTTAGGTAAAGGT

Downstream 100 bases:

>100_bases
CCTCTCATTTTACGGTGGAGTTGTTCGGTGTAACGTCCTGAACAGTATATACTTCTGGGTGTTTATTGAATTTAAATTAT
CTCTGAGTACCAATTAATGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSLVNQLSLFIDVVQQGSFTKAAALHDMDNSALSKQIKKLEAELGVQLLNRSTRTFSLTPAGEEILEQAYQLVGSLDNVK
SIADSYQAVPKGRIRITAPLHIGQGYLQPVISQFMTTYPDVEVVLMMDDKRSDIISEHFDVAFRLGRLDDSSLIAKKVAD
IRGVILASHSLIERFGEPSTPEELVNLPSVIYSNGTLTVDTVRLGESPDSSQFKSYKMKGNYKVNDVRTLLSAVQDGLGY
AVVASSNLERSIESMGLTTLLTDYPLCNQGLAIYALYPHRKQTALVREFISAVQKHIGHPPLWEQHIPNFASLYPVKKGQ

Sequences:

>Translated_320_residues
MSLVNQLSLFIDVVQQGSFTKAAALHDMDNSALSKQIKKLEAELGVQLLNRSTRTFSLTPAGEEILEQAYQLVGSLDNVK
SIADSYQAVPKGRIRITAPLHIGQGYLQPVISQFMTTYPDVEVVLMMDDKRSDIISEHFDVAFRLGRLDDSSLIAKKVAD
IRGVILASHSLIERFGEPSTPEELVNLPSVIYSNGTLTVDTVRLGESPDSSQFKSYKMKGNYKVNDVRTLLSAVQDGLGY
AVVASSNLERSIESMGLTTLLTDYPLCNQGLAIYALYPHRKQTALVREFISAVQKHIGHPPLWEQHIPNFASLYPVKKGQ
>Mature_319_residues
SLVNQLSLFIDVVQQGSFTKAAALHDMDNSALSKQIKKLEAELGVQLLNRSTRTFSLTPAGEEILEQAYQLVGSLDNVKS
IADSYQAVPKGRIRITAPLHIGQGYLQPVISQFMTTYPDVEVVLMMDDKRSDIISEHFDVAFRLGRLDDSSLIAKKVADI
RGVILASHSLIERFGEPSTPEELVNLPSVIYSNGTLTVDTVRLGESPDSSQFKSYKMKGNYKVNDVRTLLSAVQDGLGYA
VVASSNLERSIESMGLTTLLTDYPLCNQGLAIYALYPHRKQTALVREFISAVQKHIGHPPLWEQHIPNFASLYPVKKGQ

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=283, Percent_Identity=29.3286219081272, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786401, Length=299, Percent_Identity=29.7658862876254, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=27.8688524590164, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=29.5918367346939, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787128, Length=301, Percent_Identity=26.9102990033223, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789440, Length=300, Percent_Identity=24, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87081978, Length=314, Percent_Identity=26.1146496815287, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693105, Length=252, Percent_Identity=23.4126984126984, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI157672245, Length=136, Percent_Identity=31.6176470588235, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=268, Percent_Identity=24.2537313432836, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=30.8219178082192, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787530, Length=227, Percent_Identity=28.1938325991189, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35380; Mature: 35249

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVNQLSLFIDVVQQGSFTKAAALHDMDNSALSKQIKKLEAELGVQLLNRSTRTFSLTP
CCHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
AGEEILEQAYQLVGSLDNVKSIADSYQAVPKGRIRITAPLHIGQGYLQPVISQFMTTYPD
CHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCC
VEVVLMMDDKRSDIISEHFDVAFRLGRLDDSSLIAKKVADIRGVILASHSLIERFGEPST
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PEELVNLPSVIYSNGTLTVDTVRLGESPDSSQFKSYKMKGNYKVNDVRTLLSAVQDGLGY
HHHHHCCCHHEECCCCEEEEEEEECCCCCHHHHHHEECCCCEEHHHHHHHHHHHHHCCCE
AVVASSNLERSIESMGLTTLLTDYPLCNQGLAIYALYPHRKQTALVREFISAVQKHIGHP
EEEECCHHHHHHHHCCHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCC
PLWEQHIPNFASLYPVKKGQ
CCHHHHCCCHHHHCCCCCCC
>Mature Secondary Structure 
SLVNQLSLFIDVVQQGSFTKAAALHDMDNSALSKQIKKLEAELGVQLLNRSTRTFSLTP
CHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
AGEEILEQAYQLVGSLDNVKSIADSYQAVPKGRIRITAPLHIGQGYLQPVISQFMTTYPD
CHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCC
VEVVLMMDDKRSDIISEHFDVAFRLGRLDDSSLIAKKVADIRGVILASHSLIERFGEPST
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PEELVNLPSVIYSNGTLTVDTVRLGESPDSSQFKSYKMKGNYKVNDVRTLLSAVQDGLGY
HHHHHCCCHHEECCCCEEEEEEEECCCCCHHHHHHEECCCCEEHHHHHHHHHHHHHCCCE
AVVASSNLERSIESMGLTTLLTDYPLCNQGLAIYALYPHRKQTALVREFISAVQKHIGHP
EEEECCHHHHHHHHCCHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCC
PLWEQHIPNFASLYPVKKGQ
CCHHHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]