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The map label for this gene is ydeN [H]

Identifier: 59714175

GI number: 59714175

Start: 1114064

End: 1115677

Strand: Reverse

Name: ydeN [H]

Synonym: VF_A0992

Alternate gene names: 59714175

Gene position: 1115677-1114064 (Counterclockwise)

Preceding gene: 59714176

Following gene: 59714174

Centisome position: 83.86

GC content: 40.64

Gene sequence:

>1614_bases
ATGAACCTGTCCTCATCGAAGAAGACAGTAATTGCAAGCCTAGTTGCTGCTGCCTGTGTAGCTGCACCTTCGCTTTCTTA
TGCTGCAAATCACAATCCTGATCAACCTAACGTATTACTTGTCGTTATGGATGATTTAGGCACGGGCCAACTTAATTTTG
CCCTAGACAGTTTGGATAAGTCTGAATTAGCTAAGCGTTCTGTCCCTGTTCGTTATCAGGGGGATTTAGATAAAATGATC
GACGCTGCTCAGCGGGCAATGCCAAATGTTGAAAAACTGGCCGCAAATGGCGTTAAAATGACTAACGCATTTGTGGCACA
CCCTGTTTGTGGCCCATCTCGTGCAGGGATTTTTACTGGTCGTCATCCAACTAGTTTTGGTACATACAGTAATGATGATG
CAAAATTGGGTATCCCTTTAGATATCAAATTATTGCCAGCACTTTTCCAAGAAAATGGTTATCGAACAGCGACAATCGGT
AAATGGCATAATGCCAAGATTAAAGGCAAAAACTTGGTTGATGAAGATAAGCGTACACGCGATTATCATGACAACCAAAT
CACAGTAACGCCAAAAGGCTATGGCCCAGAAGAGCGTGGTTTCGATTATTCATACAGTTTTTACGCATCGGGTGCCGCTT
TATGGGATTCACCAGCTATTTGGCAAAATGGTAAAAATATCTCTGCTCCGGGTTATTTAACGCATAATTTAACCGAGCAA
GCACTGAAGTTTATTGATGAAAGTGGTGACAAACCTTTCTTTGTTAACCTCGCATTTAGCGTACCTCATATTCCATTAGA
AGAAGCATCTCCTGCAAAATACATGGATAGATTTAATACTGGTAATGTTGAGGCGGACAAGTATTTTGCGGCGATTAATG
CGGCAGATGAAAGTCTTGGTATTATTATGGATAACTTAGAGAAGAAAGGAGAGTTAGATAATACCATCATATTCTTCTTA
TCTGATAACGGAGCCGTTCATGAGTCGCCAATGCCAATGAATGGAATGGATAAAGGCTTTAAAGGGCAAATGTATAACGG
TGGTGTCAGAGTCCCATTTGTCGCTTACTGGCCAAAACACATTCCAGCTGGTGGTGAAAGCGATTCACTGATCTCAGCAT
TGGATATTTTACCAACGGCTCTAGCTGCGGCAGGCATTGATATTCCAGAAGATATGCAGGTGGATGGTAAAAACATTATG
CCTGTTTTAGAAGGGAAGACAGAAACATCACCTCACCAATACTTATACTGGGCAGGCCCTGGAGCGAAACATTACAGTGA
AGAAAATGATGCGTTCTGGTATGGCTATTGGAAGTGGATCACCTATGAAACCAATACAATTCCGAATAACCCAAATTTAG
AAAAACTGTCTAAAGGCTCATGGGCGATTCGTGATCAAGATTGGGCGTTGTATTTCTATGATGATGGTTCAAATAAGGTG
AAGCTATTTAATGATAAAGAAGATCCTTCAGAGTCGATTGATTTAGCTAAAAAATACCCTGAAAAAGTGAAAGAGATGAA
AAATGCTTTCTATAACTGGATTAAAGATAAACCAAAACCAGTTGCTTGGGGCCAAGATCGTTATCAAATCTTAACTGAAT
CAGCAAAAGACTAA

Upstream 100 bases:

>100_bases
CAACAAGGAGGAACCGCGATTGATGCCGTACCTCTGATTAAAAATACCCTACGTATTTAACGCAACACGATAAATTGAAA
ATAATAACAAGGAGTAAACA

Downstream 100 bases:

>100_bases
GTTAACGTTTTTTTAAGCCACATGACCACCGCGTTTTGTGGCTTTTTTCGTTTTGAAAGGACAATCAATAATGAAGGTAG
AAATTGAACCACAAACGTTG

Product: hypothetical protein

Products: phenol; sulfate

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MNLSSSKKTVIASLVAAACVAAPSLSYAANHNPDQPNVLLVVMDDLGTGQLNFALDSLDKSELAKRSVPVRYQGDLDKMI
DAAQRAMPNVEKLAANGVKMTNAFVAHPVCGPSRAGIFTGRHPTSFGTYSNDDAKLGIPLDIKLLPALFQENGYRTATIG
KWHNAKIKGKNLVDEDKRTRDYHDNQITVTPKGYGPEERGFDYSYSFYASGAALWDSPAIWQNGKNISAPGYLTHNLTEQ
ALKFIDESGDKPFFVNLAFSVPHIPLEEASPAKYMDRFNTGNVEADKYFAAINAADESLGIIMDNLEKKGELDNTIIFFL
SDNGAVHESPMPMNGMDKGFKGQMYNGGVRVPFVAYWPKHIPAGGESDSLISALDILPTALAAAGIDIPEDMQVDGKNIM
PVLEGKTETSPHQYLYWAGPGAKHYSEENDAFWYGYWKWITYETNTIPNNPNLEKLSKGSWAIRDQDWALYFYDDGSNKV
KLFNDKEDPSESIDLAKKYPEKVKEMKNAFYNWIKDKPKPVAWGQDRYQILTESAKD

Sequences:

>Translated_537_residues
MNLSSSKKTVIASLVAAACVAAPSLSYAANHNPDQPNVLLVVMDDLGTGQLNFALDSLDKSELAKRSVPVRYQGDLDKMI
DAAQRAMPNVEKLAANGVKMTNAFVAHPVCGPSRAGIFTGRHPTSFGTYSNDDAKLGIPLDIKLLPALFQENGYRTATIG
KWHNAKIKGKNLVDEDKRTRDYHDNQITVTPKGYGPEERGFDYSYSFYASGAALWDSPAIWQNGKNISAPGYLTHNLTEQ
ALKFIDESGDKPFFVNLAFSVPHIPLEEASPAKYMDRFNTGNVEADKYFAAINAADESLGIIMDNLEKKGELDNTIIFFL
SDNGAVHESPMPMNGMDKGFKGQMYNGGVRVPFVAYWPKHIPAGGESDSLISALDILPTALAAAGIDIPEDMQVDGKNIM
PVLEGKTETSPHQYLYWAGPGAKHYSEENDAFWYGYWKWITYETNTIPNNPNLEKLSKGSWAIRDQDWALYFYDDGSNKV
KLFNDKEDPSESIDLAKKYPEKVKEMKNAFYNWIKDKPKPVAWGQDRYQILTESAKD
>Mature_537_residues
MNLSSSKKTVIASLVAAACVAAPSLSYAANHNPDQPNVLLVVMDDLGTGQLNFALDSLDKSELAKRSVPVRYQGDLDKMI
DAAQRAMPNVEKLAANGVKMTNAFVAHPVCGPSRAGIFTGRHPTSFGTYSNDDAKLGIPLDIKLLPALFQENGYRTATIG
KWHNAKIKGKNLVDEDKRTRDYHDNQITVTPKGYGPEERGFDYSYSFYASGAALWDSPAIWQNGKNISAPGYLTHNLTEQ
ALKFIDESGDKPFFVNLAFSVPHIPLEEASPAKYMDRFNTGNVEADKYFAAINAADESLGIIMDNLEKKGELDNTIIFFL
SDNGAVHESPMPMNGMDKGFKGQMYNGGVRVPFVAYWPKHIPAGGESDSLISALDILPTALAAAGIDIPEDMQVDGKNIM
PVLEGKTETSPHQYLYWAGPGAKHYSEENDAFWYGYWKWITYETNTIPNNPNLEKLSKGSWAIRDQDWALYFYDDGSNKV
KLFNDKEDPSESIDLAKKYPEKVKEMKNAFYNWIKDKPKPVAWGQDRYQILTESAKD

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=406, Percent_Identity=29.064039408867, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI59797060, Length=464, Percent_Identity=28.2327586206897, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI146229331, Length=398, Percent_Identity=28.391959798995, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI146229329, Length=398, Percent_Identity=28.391959798995, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI6005990, Length=398, Percent_Identity=28.391959798995, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI146229324, Length=398, Percent_Identity=28.391959798995, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI109389362, Length=478, Percent_Identity=25.7322175732218, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI45430057, Length=424, Percent_Identity=26.8867924528302, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI53831991, Length=295, Percent_Identity=29.4915254237288, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI38569407, Length=303, Percent_Identity=28.7128712871287, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI38569405, Length=303, Percent_Identity=28.7128712871287, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI31742482, Length=197, Percent_Identity=26.9035532994924, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI146229327, Length=297, Percent_Identity=28.6195286195286, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI58743319, Length=188, Percent_Identity=29.7872340425532, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI157266309, Length=208, Percent_Identity=27.8846153846154, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI71852584, Length=197, Percent_Identity=24.3654822335025, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081924, Length=490, Percent_Identity=41.8367346938776, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1790112, Length=366, Percent_Identity=24.8633879781421, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1790233, Length=382, Percent_Identity=26.9633507853403, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115533416, Length=513, Percent_Identity=23.1968810916179, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI115533418, Length=460, Percent_Identity=23.9130434782609, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559078, Length=264, Percent_Identity=25, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281366397, Length=468, Percent_Identity=25.8547008547009, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI281366395, Length=468, Percent_Identity=25.8547008547009, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24666163, Length=468, Percent_Identity=25.8547008547009, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24666175, Length=424, Percent_Identity=25.7075471698113, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24666109, Length=405, Percent_Identity=25.1851851851852, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281363223, Length=421, Percent_Identity=25.8907363420428, Blast_Score=112, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.1

Molecular weight: Translated: 59617; Mature: 59617

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSSSKKTVIASLVAAACVAAPSLSYAANHNPDQPNVLLVVMDDLGTGQLNFALDSLDK
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCH
SELAKRSVPVRYQGDLDKMIDAAQRAMPNVEKLAANGVKMTNAFVAHPVCGPSRAGIFTG
HHHHHHCCCEEECCCHHHHHHHHHHHCCCHHHHHCCCEEECCEEEECCCCCCCCCCEEEC
RHPTSFGTYSNDDAKLGIPLDIKLLPALFQENGYRTATIGKWHNAKIKGKNLVDEDKRTR
CCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCCCEEEEECCCCCCEECCCCCCCCHHHHH
DYHDNQITVTPKGYGPEERGFDYSYSFYASGAALWDSPAIWQNGKNISAPGYLTHNLTEQ
CCCCCEEEEECCCCCCHHCCCCEEEEEEECCCEECCCCHHHCCCCCCCCCCEEEHHHHHH
ALKFIDESGDKPFFVNLAFSVPHIPLEEASPAKYMDRFNTGNVEADKYFAAINAADESLG
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCHHH
IIMDNLEKKGELDNTIIFFLSDNGAVHESPMPMNGMDKGFKGQMYNGGVRVPFVAYWPKH
HHHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCEECCCEECCEEEECCCC
IPAGGESDSLISALDILPTALAAAGIDIPEDMQVDGKNIMPVLEGKTETSPHQYLYWAGP
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEECCCCCCCCCCEEEECCC
GAKHYSEENDAFWYGYWKWITYETNTIPNNPNLEKLSKGSWAIRDQDWALYFYDDGSNKV
CCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHCCCCEEEECCCEEEEEEECCCCEE
KLFNDKEDPSESIDLAKKYPEKVKEMKNAFYNWIKDKPKPVAWGQDRYQILTESAKD
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MNLSSSKKTVIASLVAAACVAAPSLSYAANHNPDQPNVLLVVMDDLGTGQLNFALDSLDK
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCH
SELAKRSVPVRYQGDLDKMIDAAQRAMPNVEKLAANGVKMTNAFVAHPVCGPSRAGIFTG
HHHHHHCCCEEECCCHHHHHHHHHHHCCCHHHHHCCCEEECCEEEECCCCCCCCCCEEEC
RHPTSFGTYSNDDAKLGIPLDIKLLPALFQENGYRTATIGKWHNAKIKGKNLVDEDKRTR
CCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCCCEEEEECCCCCCEECCCCCCCCHHHHH
DYHDNQITVTPKGYGPEERGFDYSYSFYASGAALWDSPAIWQNGKNISAPGYLTHNLTEQ
CCCCCEEEEECCCCCCHHCCCCEEEEEEECCCEECCCCHHHCCCCCCCCCCEEEHHHHHH
ALKFIDESGDKPFFVNLAFSVPHIPLEEASPAKYMDRFNTGNVEADKYFAAINAADESLG
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCHHH
IIMDNLEKKGELDNTIIFFLSDNGAVHESPMPMNGMDKGFKGQMYNGGVRVPFVAYWPKH
HHHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCEECCCEECCEEEECCCC
IPAGGESDSLISALDILPTALAAAGIDIPEDMQVDGKNIMPVLEGKTETSPHQYLYWAGP
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEECCCCCCCCCCEEEECCC
GAKHYSEENDAFWYGYWKWITYETNTIPNNPNLEKLSKGSWAIRDQDWALYFYDDGSNKV
CCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHCCCCEEEECCCEEEEEEECCCCEE
KLFNDKEDPSESIDLAKKYPEKVKEMKNAFYNWIKDKPKPVAWGQDRYQILTESAKD
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phenol sulfate; H2O

Specific reaction: A phenol sulfate + H2O = a phenol + sulfate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]