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The map label for this gene is fhuA [H]

Identifier: 59713967

GI number: 59713967

Start: 877714

End: 879912

Strand: Reverse

Name: fhuA [H]

Synonym: VF_A0784

Alternate gene names: 59713967

Gene position: 879912-877714 (Counterclockwise)

Preceding gene: 59713968

Following gene: 59713966

Centisome position: 66.14

GC content: 37.24

Gene sequence:

>2199_bases
ATGAACGTATCTACAGAATATTCAAAATTTAATGTCACCCTTTTGGCAACAGCAATTGCTTCATCTTTTCTATTTCCTAT
TTCAGCAATGGCTAACGATGATAGTGCTTCTGATGATGTTGAAACCATTTCAATATTTGGTCAAGCCTACCGTAATACAG
CAACCAAAACATCTTTAGAACCAGAAGAAACCCCACAAGGGATCACTGTACTTGATGGTGAAGTATTAGAACAACGCAGT
GTTAAATCTTTGAATGAAGCATTACGTTATGTACCTGGCGTAACCACTGAACAAAAGGGCGGTGCGGTGACGATGTACGA
TACGTTTAACATTCGAGGCTTTGATGTAAACCAAAGTTATTATGATGGTTTGGTTCTGCAATATTTAAATGGATGGAATT
TACAGCCACAAATTGATCCAATTGCGATTCAGCAAATTGAAGTTTTTAAAGGTCCAACGTCAGTTTTGTACGGTTCTATG
CCACCTGGTGGCATGGTAAACATGATTGCTAAGACACCACAAAAAGAAAAAAGTACAGACGTAAAAGTTGCGACGGGTAC
TGGTAATTTAGTGGAAGCTTCTATTGATACAACTGGTCAATTTGGTGACAGTGATTTTTCATATCGTTTTATTGCATTAG
CACGTCAAAAAGACGGTCAAGTTGATTACACAGAAGAAGAGCGTTATGTAATAGCTCCGTCGGTTGATTGGCAAGTTAGT
GATCGTACATTAATTAACTTCAATATGTATTATCAAAATGACCCGTCAATGGGTATGAACTCTGCAATGCCAGCTTCAGG
CATGATTTACGATAACCCAAATGGAAGTACAGATCCGTCTACATTTGTAGGTGATAAAAATTGGAGTACGTTTGAACGTG
AATTTTTTATGGCTGGCTATAAGATCAACCATGAATTCAATAATAATTGGTCGTTCTTACAAAATTTCCGTTATATGAAT
GCGTCGTTGTACCAAGAAAATACCTATCATATTCAAAATGCTTATACACAAGACTTTGATCCATCTACAGGAGTTTTAGA
TCGAAGCATATATAGTACCGATGAAAATTCAATTGGTTATACTATTGATAACCAGCTATCAGGTCGAGTGATGGTTGGAA
GTGTTGAGCATAATTTATTGTTTGGTATTGATTATCAGAAACTTGATGGCGATTCACGTTATAAAGAGTTTGGTAAAACA
AGTCAATTTGGTGATTTCAATATATTCAACCCAAATAACAATATGATAGATAGAGGGCAGCTGTCGAATACTGCTGATTA
TAAAGATGAAATCGGTATTGAACAAACAGGTGTTTATTTTCAAGACCAAGTGCGTATAGAGCGACTAGTGTTAATTGCTG
GCGGTAGATACGATAAGTTTACATCTGATAGTGACTATAGAGGAAAATATGAAGATAAAGGTGTTTGGTATGATTATAGT
AAAAATGATAAAGCTAGCCAAAGCCAGTTCTCTTATCGTGTCGGCGCTTTATATGAGCTAGAAAGTGGTTTCTCACCATT
TATTAGTTATGCAACGAGTTTTGAACCTGTTGCTGGTTTGGACGCTCAAGGTAATTCGTATAAACCTGAACTAGGTGAGC
AAGTAGAAGTTGGTGTTAAGTATGAATCTTCAGATTATACAAAAGTAGCTTCAGCATCTTTATTTAACATTACTAAAAGT
GATGCCATGATGGCTGATCCTACTGATGCATATAATCCTCAATTGCAAATTGGTGAAATCCGTTCTCGCGGTATAGAGCT
TCAAGGTCAATGGATGATTAGTGATAGTTGGGATATTGCTGCTAACTACACCTATATAGACATGGAGATTACCGAAGATG
ATACATATAACTCTGAAGGTAAAACACCTATCTATGTGCCAACACATGCGGCGAGCTTATGGTCTAACTACTACATTTAT
GATGGTATCTTAACTGGAACGCGTATCAGTGGTGGCTTACGCTACGTAGGTGAAATGGAAATGGATGCAGCCAATACGGA
CAAAGTACCAGATTATACGCTTGCTGATGTTTCTATTGGTTATGAGCTTGATGGGATCAGTGAATCATTAACAGGGGCAA
CGGCTCAATTGAGTGCGACTAACTTGTTTAATACTGAATATTATAGCTGTTACGATTCAGCAAACTGCTGGTACGGTGCA
GAACAAACCGTTGAACTGAGCATTAATTATAACTTCTAA

Upstream 100 bases:

>100_bases
ACCAAATTGTTAACTTTCATTAGGGATAAATCATTATACTCTTGCGCAAGAGAATCATTCTCATTTGCATTTTGATTTAA
GCGTTGTAAGCAGGATTATA

Downstream 100 bases:

>100_bases
GTGAACTTGATTTAAAAATAGAGAGAAGTACGTGGCTCTTGCGTACTTCTTTTCTGCATTTTATTTAACAGAGAATAATA
TAAGTATTAGCTAAGCTTAT

Product: ferrichrome outer membrane transporter

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MNVSTEYSKFNVTLLATAIASSFLFPISAMANDDSASDDVETISIFGQAYRNTATKTSLEPEETPQGITVLDGEVLEQRS
VKSLNEALRYVPGVTTEQKGGAVTMYDTFNIRGFDVNQSYYDGLVLQYLNGWNLQPQIDPIAIQQIEVFKGPTSVLYGSM
PPGGMVNMIAKTPQKEKSTDVKVATGTGNLVEASIDTTGQFGDSDFSYRFIALARQKDGQVDYTEEERYVIAPSVDWQVS
DRTLINFNMYYQNDPSMGMNSAMPASGMIYDNPNGSTDPSTFVGDKNWSTFEREFFMAGYKINHEFNNNWSFLQNFRYMN
ASLYQENTYHIQNAYTQDFDPSTGVLDRSIYSTDENSIGYTIDNQLSGRVMVGSVEHNLLFGIDYQKLDGDSRYKEFGKT
SQFGDFNIFNPNNNMIDRGQLSNTADYKDEIGIEQTGVYFQDQVRIERLVLIAGGRYDKFTSDSDYRGKYEDKGVWYDYS
KNDKASQSQFSYRVGALYELESGFSPFISYATSFEPVAGLDAQGNSYKPELGEQVEVGVKYESSDYTKVASASLFNITKS
DAMMADPTDAYNPQLQIGEIRSRGIELQGQWMISDSWDIAANYTYIDMEITEDDTYNSEGKTPIYVPTHAASLWSNYYIY
DGILTGTRISGGLRYVGEMEMDAANTDKVPDYTLADVSIGYELDGISESLTGATAQLSATNLFNTEYYSCYDSANCWYGA
EQTVELSINYNF

Sequences:

>Translated_732_residues
MNVSTEYSKFNVTLLATAIASSFLFPISAMANDDSASDDVETISIFGQAYRNTATKTSLEPEETPQGITVLDGEVLEQRS
VKSLNEALRYVPGVTTEQKGGAVTMYDTFNIRGFDVNQSYYDGLVLQYLNGWNLQPQIDPIAIQQIEVFKGPTSVLYGSM
PPGGMVNMIAKTPQKEKSTDVKVATGTGNLVEASIDTTGQFGDSDFSYRFIALARQKDGQVDYTEEERYVIAPSVDWQVS
DRTLINFNMYYQNDPSMGMNSAMPASGMIYDNPNGSTDPSTFVGDKNWSTFEREFFMAGYKINHEFNNNWSFLQNFRYMN
ASLYQENTYHIQNAYTQDFDPSTGVLDRSIYSTDENSIGYTIDNQLSGRVMVGSVEHNLLFGIDYQKLDGDSRYKEFGKT
SQFGDFNIFNPNNNMIDRGQLSNTADYKDEIGIEQTGVYFQDQVRIERLVLIAGGRYDKFTSDSDYRGKYEDKGVWYDYS
KNDKASQSQFSYRVGALYELESGFSPFISYATSFEPVAGLDAQGNSYKPELGEQVEVGVKYESSDYTKVASASLFNITKS
DAMMADPTDAYNPQLQIGEIRSRGIELQGQWMISDSWDIAANYTYIDMEITEDDTYNSEGKTPIYVPTHAASLWSNYYIY
DGILTGTRISGGLRYVGEMEMDAANTDKVPDYTLADVSIGYELDGISESLTGATAQLSATNLFNTEYYSCYDSANCWYGA
EQTVELSINYNF
>Mature_732_residues
MNVSTEYSKFNVTLLATAIASSFLFPISAMANDDSASDDVETISIFGQAYRNTATKTSLEPEETPQGITVLDGEVLEQRS
VKSLNEALRYVPGVTTEQKGGAVTMYDTFNIRGFDVNQSYYDGLVLQYLNGWNLQPQIDPIAIQQIEVFKGPTSVLYGSM
PPGGMVNMIAKTPQKEKSTDVKVATGTGNLVEASIDTTGQFGDSDFSYRFIALARQKDGQVDYTEEERYVIAPSVDWQVS
DRTLINFNMYYQNDPSMGMNSAMPASGMIYDNPNGSTDPSTFVGDKNWSTFEREFFMAGYKINHEFNNNWSFLQNFRYMN
ASLYQENTYHIQNAYTQDFDPSTGVLDRSIYSTDENSIGYTIDNQLSGRVMVGSVEHNLLFGIDYQKLDGDSRYKEFGKT
SQFGDFNIFNPNNNMIDRGQLSNTADYKDEIGIEQTGVYFQDQVRIERLVLIAGGRYDKFTSDSDYRGKYEDKGVWYDYS
KNDKASQSQFSYRVGALYELESGFSPFISYATSFEPVAGLDAQGNSYKPELGEQVEVGVKYESSDYTKVASASLFNITKS
DAMMADPTDAYNPQLQIGEIRSRGIELQGQWMISDSWDIAANYTYIDMEITEDDTYNSEGKTPIYVPTHAASLWSNYYIY
DGILTGTRISGGLRYVGEMEMDAANTDKVPDYTLADVSIGYELDGISESLTGATAQLSATNLFNTEYYSCYDSANCWYGA
EQTVELSINYNF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=727, Percent_Identity=34.3878954607978, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1787024, Length=724, Percent_Identity=23.3425414364641, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787344, Length=696, Percent_Identity=21.4080459770115, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787723, Length=682, Percent_Identity=21.7008797653959, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82025; Mature: 82025

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSTEYSKFNVTLLATAIASSFLFPISAMANDDSASDDVETISIFGQAYRNTATKTSLE
CCCCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PEETPQGITVLDGEVLEQRSVKSLNEALRYVPGVTTEQKGGAVTMYDTFNIRGFDVNQSY
CCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCHH
YDGLVLQYLNGWNLQPQIDPIAIQQIEVFKGPTSVLYGSMPPGGMVNMIAKTPQKEKSTD
HCCCCEEHHCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCCHHHHHHCCCCCCCCCC
VKVATGTGNLVEASIDTTGQFGDSDFSYRFIALARQKDGQVDYTEEERYVIAPSVDWQVS
EEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCEEEC
DRTLINFNMYYQNDPSMGMNSAMPASGMIYDNPNGSTDPSTFVGDKNWSTFEREFFMAGY
CEEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCCCHHHHEEEEECE
KINHEFNNNWSFLQNFRYMNASLYQENTYHIQNAYTQDFDPSTGVLDRSIYSTDENSIGY
EEEEEECCCHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCE
TIDNQLSGRVMVGSVEHNLLFGIDYQKLDGDSRYKEFGKTSQFGDFNIFNPNNNMIDRGQ
EECCCCCCEEEEEEECCCEEEEECHHHCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCCC
LSNTADYKDEIGIEQTGVYFQDQVRIERLVLIAGGRYDKFTSDSDYRGKYEDKGVWYDYS
CCCCCCCHHHCCCCCCCCEEEECEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEC
KNDKASQSQFSYRVGALYELESGFSPFISYATSFEPVAGLDAQGNSYKPELGEQVEVGVK
CCCCCCHHHHEEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
YESSDYTKVASASLFNITKSDAMMADPTDAYNPQLQIGEIRSRGIELQGQWMISDSWDIA
ECCCCCCCHHCCEEEEEECCCCEEECCCCCCCCCEEEECHHHCCEEEEEEEEEECCCCEE
ANYTYIDMEITEDDTYNSEGKTPIYVPTHAASLWSNYYIYDGILTGTRISGGLRYVGEME
EEEEEEEEEECCCCCCCCCCCEEEEECCCHHHHHCCEEEEEEEEECCEECCCEEEEEEEE
MDAANTDKVPDYTLADVSIGYELDGISESLTGATAQLSATNLFNTEYYSCYDSANCWYGA
ECCCCCCCCCCEEEEEEEECEEECCCCHHHCCCEEEEEECEECCCCEEEEECCCCCEECC
EQTVELSINYNF
CEEEEEEEEECC
>Mature Secondary Structure
MNVSTEYSKFNVTLLATAIASSFLFPISAMANDDSASDDVETISIFGQAYRNTATKTSLE
CCCCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PEETPQGITVLDGEVLEQRSVKSLNEALRYVPGVTTEQKGGAVTMYDTFNIRGFDVNQSY
CCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCHH
YDGLVLQYLNGWNLQPQIDPIAIQQIEVFKGPTSVLYGSMPPGGMVNMIAKTPQKEKSTD
HCCCCEEHHCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCCHHHHHHCCCCCCCCCC
VKVATGTGNLVEASIDTTGQFGDSDFSYRFIALARQKDGQVDYTEEERYVIAPSVDWQVS
EEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCEEEC
DRTLINFNMYYQNDPSMGMNSAMPASGMIYDNPNGSTDPSTFVGDKNWSTFEREFFMAGY
CEEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCCCCHHHHEEEEECE
KINHEFNNNWSFLQNFRYMNASLYQENTYHIQNAYTQDFDPSTGVLDRSIYSTDENSIGY
EEEEEECCCHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCE
TIDNQLSGRVMVGSVEHNLLFGIDYQKLDGDSRYKEFGKTSQFGDFNIFNPNNNMIDRGQ
EECCCCCCEEEEEEECCCEEEEECHHHCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCCC
LSNTADYKDEIGIEQTGVYFQDQVRIERLVLIAGGRYDKFTSDSDYRGKYEDKGVWYDYS
CCCCCCCHHHCCCCCCCCEEEECEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEC
KNDKASQSQFSYRVGALYELESGFSPFISYATSFEPVAGLDAQGNSYKPELGEQVEVGVK
CCCCCCHHHHEEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
YESSDYTKVASASLFNITKSDAMMADPTDAYNPQLQIGEIRSRGIELQGQWMISDSWDIA
ECCCCCCCHHCCEEEEEECCCCEEECCCCCCCCCEEEECHHHCCEEEEEEEEEECCCCEE
ANYTYIDMEITEDDTYNSEGKTPIYVPTHAASLWSNYYIYDGILTGTRISGGLRYVGEME
EEEEEEEEEECCCCCCCCCCCEEEEECCCHHHHHCCEEEEEEEEECCEECCCEEEEEEEE
MDAANTDKVPDYTLADVSIGYELDGISESLTGATAQLSATNLFNTEYYSCYDSANCWYGA
ECCCCCCCCCCEEEEEEEECEEECCCCHHHCCCEEEEEECEECCCCEEEEECCCCCEECC
EQTVELSINYNF
CEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]