| Definition | Vibrio fischeri ES114 chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_006841 |
| Length | 1,330,333 |
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The map label for this gene is pntA [H]
Identifier: 59713769
GI number: 59713769
Start: 669605
End: 671161
Strand: Reverse
Name: pntA [H]
Synonym: VF_A0586
Alternate gene names: 59713769
Gene position: 671161-669605 (Counterclockwise)
Preceding gene: 59713770
Following gene: 59713768
Centisome position: 50.45
GC content: 43.1
Gene sequence:
>1557_bases ATGCAAATTGGTGTACCTAGAGAAGTCTTCGCGGGTGAAACCCGTGTTGCTGCAACGCCTAAAACGGTTGAGCAGCTTAT CAAGCTTGGTTTTACAGTTGCTGTAGAATCAAACGCTGGTATCTTAGCGAGCTTTGATGATTCAGCTTTTGAACAAGCTG GCGCAACCGTTGTTTCAACAGATGATGTATGGAAATCAGAACTGATTCTGAAAGTAAATGCACCTCAAGTAAATGAAGCA ACGGGTGTTGATGAGTTCGATTTAATTCAAGATGGCGCAAGCTTAATCAGCTTTATTTGGCCTGCACAAAATGAAGAACT ACTAGCGAAGTTAGCAACAAAGAACATTAACGTTCTTGCTATGGATTCGGTTCCTCGTATTTCTCGTGCTCAGGCGCTTG ATGCCCTAAGTTCAATGGCAAACATTGCAGGTTACCGTGCTGTAGTTGAAGCTGCGCATGAATTTGGCCGCTTCTTTACC GGTCAAATTACAGCGGCTGGTAAAGTTCCACCGGCTAAAGTACTTGTTGCTGGTGCTGGTGTTGCAGGTCTTGCTGCTAT CGGTGCTGCTGGTAGCCTTGGTGCAATCGTTCGTGCATTTGACGTTCGTCCAGAAGTAAAAGAACAAGTGCAATCAATGG GTGCAGAATTCCTTGAAGTTGATTTCAAAGAAAACTCTGGCTCAGGTGATGGCTACGCTAAAGAAATGTCTGATGAGTTC AACAAAAAAGCAGAAGAGCTATATGCGGCTCAAGCTAAAGACGTTGATATCATCATCACAACAGCGCTTATCCCAGGTCG TCCAGCGCCGAAGCTAATCACCAAAGAAATGGTTGATAGCATGAAAGCGGGCAGTGTTATTGTCGATTTAGCGGCAGCAA ACGGCGGTAACTGTGAATACACAGTAAAAGACGAAGTTTTCGTAACAGAGAATGGCGTTAAGATCGTTGGTTATACTGAT ATGGTTGGTCGTCTACCAACTCAATCATCTCAGCTATACGGCACAAACCTAGTAAACCTTCTAAAACTTTTATGTAAAGA AAAAGATGGCAACATCAACATCGATTTTGAAGACGTTGTTCTTCGTGGTGTAACAGTTGTTAAAGAAGGTGAAGTAACTT GGCCTGCGCCACCAATTCAAGTGTCAGCACAACCACAAGCGAAAGCAGCACCAAAAGCTAAGGTTGAGCCAAAAGTTGAA GAGCCAACATCACCAATTAAGAAATTTGCAATGATCGGTGCTGGTATTGCAGCATTCGGTTGGGTTGCATCTGTCGCTCC AGCAGCATTCTTAGCACACTTTACTGTATTCGTACTTGCGTGTGTGGTTGGTTATTACGTGGTATGGAATGTAAGTCATT CACTTCATACACCACTAATGTCAGTAACAAACGCTATCTCAGGCATCATCATTGTAGGTGCATTACTGCAAGTGGGTCAG GGTAATGGTGTCGTTTCATTTTTAGCATTTATCGCAGTTCTTATCGCAAGTATTAATATATTTGGCGGTTTCGCTGTAAC CAAGCGTATGCTTGAAATGTTCCGTAAAGATAAATAA
Upstream 100 bases:
>100_bases AGTAATGAAAATATGTCATTTTATTACAAAACACTTGAATTAATCGGTTAGCTTGGATAAAACTAACTGACAAATTCATG CCAATAGTCAAGGAATTACT
Downstream 100 bases:
>100_bases GGAGTAGGACAATGTCAGCAGGATTAGTTCAAGCAGCGTATATTGTATCTGCCGTTCTATTTATCATGAGTTTAGCAGGT CTGTCTAAACAAGAGACAGC
Product: NAD(P) transhydrogenase subunit alpha
Products: NA
Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha; Pyridine nucleotide transhydrogenase subunit alpha [H]
Number of amino acids: Translated: 518; Mature: 518
Protein sequence:
>518_residues MQIGVPREVFAGETRVAATPKTVEQLIKLGFTVAVESNAGILASFDDSAFEQAGATVVSTDDVWKSELILKVNAPQVNEA TGVDEFDLIQDGASLISFIWPAQNEELLAKLATKNINVLAMDSVPRISRAQALDALSSMANIAGYRAVVEAAHEFGRFFT GQITAAGKVPPAKVLVAGAGVAGLAAIGAAGSLGAIVRAFDVRPEVKEQVQSMGAEFLEVDFKENSGSGDGYAKEMSDEF NKKAEELYAAQAKDVDIIITTALIPGRPAPKLITKEMVDSMKAGSVIVDLAAANGGNCEYTVKDEVFVTENGVKIVGYTD MVGRLPTQSSQLYGTNLVNLLKLLCKEKDGNINIDFEDVVLRGVTVVKEGEVTWPAPPIQVSAQPQAKAAPKAKVEPKVE EPTSPIKKFAMIGAGIAAFGWVASVAPAAFLAHFTVFVLACVVGYYVVWNVSHSLHTPLMSVTNAISGIIIVGALLQVGQ GNGVVSFLAFIAVLIASINIFGGFAVTKRMLEMFRKDK
Sequences:
>Translated_518_residues MQIGVPREVFAGETRVAATPKTVEQLIKLGFTVAVESNAGILASFDDSAFEQAGATVVSTDDVWKSELILKVNAPQVNEA TGVDEFDLIQDGASLISFIWPAQNEELLAKLATKNINVLAMDSVPRISRAQALDALSSMANIAGYRAVVEAAHEFGRFFT GQITAAGKVPPAKVLVAGAGVAGLAAIGAAGSLGAIVRAFDVRPEVKEQVQSMGAEFLEVDFKENSGSGDGYAKEMSDEF NKKAEELYAAQAKDVDIIITTALIPGRPAPKLITKEMVDSMKAGSVIVDLAAANGGNCEYTVKDEVFVTENGVKIVGYTD MVGRLPTQSSQLYGTNLVNLLKLLCKEKDGNINIDFEDVVLRGVTVVKEGEVTWPAPPIQVSAQPQAKAAPKAKVEPKVE EPTSPIKKFAMIGAGIAAFGWVASVAPAAFLAHFTVFVLACVVGYYVVWNVSHSLHTPLMSVTNAISGIIIVGALLQVGQ GNGVVSFLAFIAVLIASINIFGGFAVTKRMLEMFRKDK >Mature_518_residues MQIGVPREVFAGETRVAATPKTVEQLIKLGFTVAVESNAGILASFDDSAFEQAGATVVSTDDVWKSELILKVNAPQVNEA TGVDEFDLIQDGASLISFIWPAQNEELLAKLATKNINVLAMDSVPRISRAQALDALSSMANIAGYRAVVEAAHEFGRFFT GQITAAGKVPPAKVLVAGAGVAGLAAIGAAGSLGAIVRAFDVRPEVKEQVQSMGAEFLEVDFKENSGSGDGYAKEMSDEF NKKAEELYAAQAKDVDIIITTALIPGRPAPKLITKEMVDSMKAGSVIVDLAAANGGNCEYTVKDEVFVTENGVKIVGYTD MVGRLPTQSSQLYGTNLVNLLKLLCKEKDGNINIDFEDVVLRGVTVVKEGEVTWPAPPIQVSAQPQAKAAPKAKVEPKVE EPTSPIKKFAMIGAGIAAFGWVASVAPAAFLAHFTVFVLACVVGYYVVWNVSHSLHTPLMSVTNAISGIIIVGALLQVGQ GNGVVSFLAFIAVLIASINIFGGFAVTKRMLEMFRKDK
Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]
COG id: COG3288
COG function: function code C; NAD/NADP transhydrogenase alpha subunit
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the AlaDH/PNT family [H]
Homologues:
Organism=Homo sapiens, GI122939155, Length=533, Percent_Identity=49.53095684803, Blast_Score=476, Evalue=1e-134, Organism=Homo sapiens, GI122939153, Length=533, Percent_Identity=49.53095684803, Blast_Score=476, Evalue=1e-134, Organism=Escherichia coli, GI1787887, Length=517, Percent_Identity=76.78916827853, Blast_Score=799, Evalue=0.0, Organism=Caenorhabditis elegans, GI17550456, Length=527, Percent_Identity=50.0948766603416, Blast_Score=466, Evalue=1e-131,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR007698 - InterPro: IPR008142 - InterPro: IPR008143 - InterPro: IPR007886 - InterPro: IPR004571 [H]
Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]
EC number: =1.6.1.2 [H]
Molecular weight: Translated: 54808; Mature: 54808
Theoretical pI: Translated: 4.87; Mature: 4.87
Prosite motif: PS00836 ALADH_PNT_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQIGVPREVFAGETRVAATPKTVEQLIKLGFTVAVESNAGILASFDDSAFEQAGATVVST CCCCCCHHHHCCCCEEECCHHHHHHHHHCCEEEEEECCCCEEEECCCHHHHHCCCEEEEC DDVWKSELILKVNAPQVNEATGVDEFDLIQDGASLISFIWPAQNEELLAKLATKNINVLA CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEE MDSVPRISRAQALDALSSMANIAGYRAVVEAAHEFGRFFTGQITAAGKVPPAKVLVAGAG ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEECCCCCCCCEEEECCC VAGLAAIGAAGSLGAIVRAFDVRPEVKEQVQSMGAEFLEVDFKENSGSGDGYAKEMSDEF HHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHH NKKAEELYAAQAKDVDIIITTALIPGRPAPKLITKEMVDSMKAGSVIVDLAAANGGNCEY HHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEE TVKDEVFVTENGVKIVGYTDMVGRLPTQSSQLYGTNLVNLLKLLCKEKDGNINIDFEDVV EECCEEEEECCCEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCHHHHH LRGVTVVKEGEVTWPAPPIQVSAQPQAKAAPKAKVEPKVEEPTSPIKKFAMIGAGIAAFG HHCEEEEECCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHH WVASVAPAAFLAHFTVFVLACVVGYYVVWNVSHSLHTPLMSVTNAISGIIIVGALLQVGQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC GNGVVSFLAFIAVLIASINIFGGFAVTKRMLEMFRKDK CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MQIGVPREVFAGETRVAATPKTVEQLIKLGFTVAVESNAGILASFDDSAFEQAGATVVST CCCCCCHHHHCCCCEEECCHHHHHHHHHCCEEEEEECCCCEEEECCCHHHHHCCCEEEEC DDVWKSELILKVNAPQVNEATGVDEFDLIQDGASLISFIWPAQNEELLAKLATKNINVLA CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEE MDSVPRISRAQALDALSSMANIAGYRAVVEAAHEFGRFFTGQITAAGKVPPAKVLVAGAG ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEECCCCCCCCEEEECCC VAGLAAIGAAGSLGAIVRAFDVRPEVKEQVQSMGAEFLEVDFKENSGSGDGYAKEMSDEF HHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHH NKKAEELYAAQAKDVDIIITTALIPGRPAPKLITKEMVDSMKAGSVIVDLAAANGGNCEY HHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEE TVKDEVFVTENGVKIVGYTDMVGRLPTQSSQLYGTNLVNLLKLLCKEKDGNINIDFEDVV EECCEEEEECCCEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCHHHHH LRGVTVVKEGEVTWPAPPIQVSAQPQAKAAPKAKVEPKVEEPTSPIKKFAMIGAGIAAFG HHCEEEEECCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHH WVASVAPAAFLAHFTVFVLACVVGYYVVWNVSHSLHTPLMSVTNAISGIIIVGALLQVGQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC GNGVVSFLAFIAVLIASINIFGGFAVTKRMLEMFRKDK CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3525165; 1633824; 9097039; 9278503; 1932078 [H]