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The map label for this gene is tcpI [H]

Identifier: 59713631

GI number: 59713631

Start: 515255

End: 516883

Strand: Reverse

Name: tcpI [H]

Synonym: VF_A0448

Alternate gene names: 59713631

Gene position: 516883-515255 (Counterclockwise)

Preceding gene: 59713632

Following gene: 59713630

Centisome position: 38.85

GC content: 37.81

Gene sequence:

>1629_bases
ATGCAATTTTCATTAAAAAATACGTCTATACGTATTCAAGTTTTACTACCCGTTGTACTCACCGCACTAGCTCTGTTCAT
TTCTTTAGGTTTCACCGCCTCTACACTTGAGGAAGAACAAGATATTATTGCTAGCAATACTGATTCTTTCGTCTTCTATA
AAGACCAACTTGCAAAAGTTGATGATGAAGTCTATCCCCTACGTATCAGTGCTGTTTATGCCATTTATGATACGGATCGT
CGTGCAAACTTCACGAATGAATTACGAAATAAAGTAGATGATATCAATGTATTATTGGATGAACTAGAAGCAAGAAAAAC
ATTCGCTAAGGAAGTTAATCTAGTTCGTACTAATATCAATAACTACGTTCAGTTTTCCCATAAGGTTATTGAATATCTAA
ATAAAAAAGAAAGTGGTCAGGCCGTTTCTCAAAGTTACGATGCGCTTATCTCGCAATATCGTAATATTGGTAATAGCATG
GTTTCTTCTATCAATGCTCTTTCTCAACGTGTGAATGAGTTTTCTGATATTGCAATGAAAGAAAGCTATGAGAAAAACAC
TCAAGTTAAAACCACAGCAGGTCTAACTATTTTAGCTGTCTTTATTATTTCGATGATCACTGCATGGTGGCTTTCAGGCT
TAATTGTTAATCCAATTCAACAAATTCAATTAATTATCCGTCGCTTAGCTGAAGGTGATTTAACGGTACGAGCTAATGCC
GATGGTGATAATGAGATTGCAACATTAAGCAAAGACATTAATACCACAGCATCTCAACTACAAACCACAGTAGAAGCATT
ATCACGCATAAGTGAAGATGTTGCAGCAGCCTCAACAGAACTAGCAGCTGTAATGACTGAAGCGGAAAACAACTCACAAC
AAGAACTAAGTGAAATCGAACAAGTCGCTTCTGCTGTTAATGAACTATCAAGTACAGCTAATAACGTGAGTGACAATGCA
TTAGCGGCAGATAAAACCGCACGTGAAACAAATGAATTGGCTCATAATGGATTAGATATCTTTACTCAAAGTAATAAAGC
AAGTGAAGAAATGGGTTCAGCGCTAACAGACGCGGCAGTGGTCGTTAATCGCCTGAAAGAACAGTCTGAGCAGATAAACA
ATGTCGTTGAAGTTATTCGTGGCGTGTCTGATCAAACTAACCTACTCGCATTGAATGCGGCAATTGAAGCTGCTCGTGCT
GGTGAATCTGGTCGAGGTTTTGCGGTTGTTGCTGATGAAGTTCGTATGCTTGCAGCTCGTACGCAAGATTCAACCCAAGA
AATTCAAACGATTATTGAATCACTTCAAGAGCAATCTAATCTTGCTAATGCAAGCATGGAGTCAAGCTTAGATAAATTGG
AATTAAATAAAGAGCTAACAGCAAAAGCTGGTGATGCCCTACTTCAAATTACCAATTCAATTGCATCGATCAATGATATG
AATACGCAAGTTGCAACAGCTGCTGAAGAACAATCTCAAGTAACTCAAGACATTAATCGCAACGTGGTAAACATGTCTGA
ATTAGTGAATCAGAATGTTACAGGCATCAGCCAAAGCGCAAGTGCAAGTAATGAACTATCAAAGCTGGCTGAACAACAAA
AAGAACAGTTATCATTCTTTAAGTTGTAA

Upstream 100 bases:

>100_bases
TACATTTGCCATCGACAAAAGTGTGACAAAAGTCTAAAATTCGAGAAAATGCAAAATAAATGTAAATTTACAATCATTTT
CTCAAATTTAAGAGGCTTTA

Downstream 100 bases:

>100_bases
TGTAAGTATCCATAGCGAATTAAAGCAGCAAGGTTAATCTCTTGCTGCTTTTTTGTATCTATAAAAAATGAATTTACGTT
CAATTAATCTAGATCAATTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MQFSLKNTSIRIQVLLPVVLTALALFISLGFTASTLEEEQDIIASNTDSFVFYKDQLAKVDDEVYPLRISAVYAIYDTDR
RANFTNELRNKVDDINVLLDELEARKTFAKEVNLVRTNINNYVQFSHKVIEYLNKKESGQAVSQSYDALISQYRNIGNSM
VSSINALSQRVNEFSDIAMKESYEKNTQVKTTAGLTILAVFIISMITAWWLSGLIVNPIQQIQLIIRRLAEGDLTVRANA
DGDNEIATLSKDINTTASQLQTTVEALSRISEDVAAASTELAAVMTEAENNSQQELSEIEQVASAVNELSSTANNVSDNA
LAADKTARETNELAHNGLDIFTQSNKASEEMGSALTDAAVVVNRLKEQSEQINNVVEVIRGVSDQTNLLALNAAIEAARA
GESGRGFAVVADEVRMLAARTQDSTQEIQTIIESLQEQSNLANASMESSLDKLELNKELTAKAGDALLQITNSIASINDM
NTQVATAAEEQSQVTQDINRNVVNMSELVNQNVTGISQSASASNELSKLAEQQKEQLSFFKL

Sequences:

>Translated_542_residues
MQFSLKNTSIRIQVLLPVVLTALALFISLGFTASTLEEEQDIIASNTDSFVFYKDQLAKVDDEVYPLRISAVYAIYDTDR
RANFTNELRNKVDDINVLLDELEARKTFAKEVNLVRTNINNYVQFSHKVIEYLNKKESGQAVSQSYDALISQYRNIGNSM
VSSINALSQRVNEFSDIAMKESYEKNTQVKTTAGLTILAVFIISMITAWWLSGLIVNPIQQIQLIIRRLAEGDLTVRANA
DGDNEIATLSKDINTTASQLQTTVEALSRISEDVAAASTELAAVMTEAENNSQQELSEIEQVASAVNELSSTANNVSDNA
LAADKTARETNELAHNGLDIFTQSNKASEEMGSALTDAAVVVNRLKEQSEQINNVVEVIRGVSDQTNLLALNAAIEAARA
GESGRGFAVVADEVRMLAARTQDSTQEIQTIIESLQEQSNLANASMESSLDKLELNKELTAKAGDALLQITNSIASINDM
NTQVATAAEEQSQVTQDINRNVVNMSELVNQNVTGISQSASASNELSKLAEQQKEQLSFFKL
>Mature_542_residues
MQFSLKNTSIRIQVLLPVVLTALALFISLGFTASTLEEEQDIIASNTDSFVFYKDQLAKVDDEVYPLRISAVYAIYDTDR
RANFTNELRNKVDDINVLLDELEARKTFAKEVNLVRTNINNYVQFSHKVIEYLNKKESGQAVSQSYDALISQYRNIGNSM
VSSINALSQRVNEFSDIAMKESYEKNTQVKTTAGLTILAVFIISMITAWWLSGLIVNPIQQIQLIIRRLAEGDLTVRANA
DGDNEIATLSKDINTTASQLQTTVEALSRISEDVAAASTELAAVMTEAENNSQQELSEIEQVASAVNELSSTANNVSDNA
LAADKTARETNELAHNGLDIFTQSNKASEEMGSALTDAAVVVNRLKEQSEQINNVVEVIRGVSDQTNLLALNAAIEAARA
GESGRGFAVVADEVRMLAARTQDSTQEIQTIIESLQEQSNLANASMESSLDKLELNKELTAKAGDALLQITNSIASINDM
NTQVATAAEEQSQVTQDINRNVVNMSELVNQNVTGISQSASASNELSKLAEQQKEQLSFFKL

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=379, Percent_Identity=27.4406332453826, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788194, Length=360, Percent_Identity=27.7777777777778, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=29.8701298701299, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI2367378, Length=320, Percent_Identity=28.125, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789453, Length=329, Percent_Identity=25.2279635258359, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59313; Mature: 59313

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSLKNTSIRIQVLLPVVLTALALFISLGFTASTLEEEQDIIASNTDSFVFYKDQLAKV
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHC
DDEVYPLRISAVYAIYDTDRRANFTNELRNKVDDINVLLDELEARKTFAKEVNLVRTNIN
CCCCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NYVQFSHKVIEYLNKKESGQAVSQSYDALISQYRNIGNSMVSSINALSQRVNEFSDIAMK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESYEKNTQVKTTAGLTILAVFIISMITAWWLSGLIVNPIQQIQLIIRRLAEGDLTVRANA
HHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
DGDNEIATLSKDINTTASQLQTTVEALSRISEDVAAASTELAAVMTEAENNSQQELSEIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QVASAVNELSSTANNVSDNALAADKTARETNELAHNGLDIFTQSNKASEEMGSALTDAAV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHH
VVNRLKEQSEQINNVVEVIRGVSDQTNLLALNAAIEAARAGESGRGFAVVADEVRMLAAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TQDSTQEIQTIIESLQEQSNLANASMESSLDKLELNKELTAKAGDALLQITNSIASINDM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCC
NTQVATAAEEQSQVTQDINRNVVNMSELVNQNVTGISQSASASNELSKLAEQQKEQLSFF
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
KL
CC
>Mature Secondary Structure
MQFSLKNTSIRIQVLLPVVLTALALFISLGFTASTLEEEQDIIASNTDSFVFYKDQLAKV
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHC
DDEVYPLRISAVYAIYDTDRRANFTNELRNKVDDINVLLDELEARKTFAKEVNLVRTNIN
CCCCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NYVQFSHKVIEYLNKKESGQAVSQSYDALISQYRNIGNSMVSSINALSQRVNEFSDIAMK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESYEKNTQVKTTAGLTILAVFIISMITAWWLSGLIVNPIQQIQLIIRRLAEGDLTVRANA
HHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
DGDNEIATLSKDINTTASQLQTTVEALSRISEDVAAASTELAAVMTEAENNSQQELSEIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QVASAVNELSSTANNVSDNALAADKTARETNELAHNGLDIFTQSNKASEEMGSALTDAAV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHH
VVNRLKEQSEQINNVVEVIRGVSDQTNLLALNAAIEAARAGESGRGFAVVADEVRMLAAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TQDSTQEIQTIIESLQEQSNLANASMESSLDKLELNKELTAKAGDALLQITNSIASINDM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCC
NTQVATAAEEQSQVTQDINRNVVNMSELVNQNVTGISQSASASNELSKLAEQQKEQLSFF
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
KL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]