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The map label for this gene is yhcK [H]

Identifier: 59713564

GI number: 59713564

Start: 429932

End: 431086

Strand: Reverse

Name: yhcK [H]

Synonym: VF_A0381

Alternate gene names: 59713564

Gene position: 431086-429932 (Counterclockwise)

Preceding gene: 59713566

Following gene: 59713563

Centisome position: 32.4

GC content: 37.84

Gene sequence:

>1155_bases
ATGGATGGCATAATCCAACTCTCATCAGAGAATCAAGGGTTCTCCTATATACTGCCCTATATTGTATTATCTATCGTTTT
ACTACTAAGTCAGCCTTTTAACCAAGGACGTATTGGTATGATAGCGATAAGTATGGCTATCGCTTATTGGATAATTCAAG
AAAGGTTGCAAGTACCATTATCATACGGTACGACACGAATTGAATTTACATTAACCGCCTTTTTATTACCTATCTGCATG
ATGGCTACATTTATTTTCCCTGAACGTCGAATTTTCTCTAAGTTCGGTGCGGGTTATTTATGCATATTACTCTTCATGTT
TTTCTGGTGCTGGATAATAACGGTACACTTTGCTGATAATGACATGACTGAAATATGGCAAACCTATTTGCTCAATATTC
CAGAAATCTCACCTCTGCCTGTTATTGTTGTTCTTTATAGTATTGTAATGTGTGGCTTATCCGCTATTTTCGTTTTAACT
CGAAGTAACAATACGGATCTTGCGTCTTACACGTGCTTACTTTATTCATCACTTACTTTTTCATTATTTAGTGTTGATTA
CATCTCAAGCACGATGTTTTCAATTGCTGGCTTACTTCTGCTTCTTTACATTATTTCAGCAAGCCATGAATTGGCGTTTA
TCGATCAGTTAACTGGGATTCCGGGGCGACGAGCTCTAGAATCTGAAATGAAACACCTTGGTCGCACCTACACCATTGCA
ATGCTTGATGTCGACCATTTTAAAAAGTTTAATGATACTTATGGACACGATACTGGTGATGACGTGCTTAAGTTAGTTGC
CAGTATCATGGCTCAAACTGGTGGTAACGCGAAAGTTTATCGTTATGGTGGCGAAGAATTTACGGTTTTATTTAAAGGTA
AAACAGCAAAGCAAAGTTTAGAATATCTTGAAGAGTTACGAGAAGACATCGCTGATTATGATTTAATTATTCGTGATACT
TCTACTCGTCCTAAAGATAACAAAGAAGGACAAGCTAAGCGTGGTAAAGCGAATAAAACAAAAGTCGTAAACGTAACCAT
TAGTATTGGTGTTGCCGATAGCGAAGATTTAAGAAAGCCACAGCTAGTTATTAAAGCTGCCGACGAAGCGTTATACAGAG
CCAAAGAAGGTGGACGTAACTGCGTCAGCGAATAA

Upstream 100 bases:

>100_bases
TATAGGATTAGTTAAAAAAATAATGTCTTTTAACCTTCTCAGCCATCCTTTATTTAAATTATTGCTCCCTATTATCATAG
TTGTATCTGTGATTACTGGA

Downstream 100 bases:

>100_bases
CCAACCCAGTATAAAAAACAATCAAAAAAACCGACTCATTTGCTTATAGTCGGTTTTTTTGTTTCTAAAAACTTATTAAC
CTTGCGTATTGTTCTTACAA

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MDGIIQLSSENQGFSYILPYIVLSIVLLLSQPFNQGRIGMIAISMAIAYWIIQERLQVPLSYGTTRIEFTLTAFLLPICM
MATFIFPERRIFSKFGAGYLCILLFMFFWCWIITVHFADNDMTEIWQTYLLNIPEISPLPVIVVLYSIVMCGLSAIFVLT
RSNNTDLASYTCLLYSSLTFSLFSVDYISSTMFSIAGLLLLLYIISASHELAFIDQLTGIPGRRALESEMKHLGRTYTIA
MLDVDHFKKFNDTYGHDTGDDVLKLVASIMAQTGGNAKVYRYGGEEFTVLFKGKTAKQSLEYLEELREDIADYDLIIRDT
STRPKDNKEGQAKRGKANKTKVVNVTISIGVADSEDLRKPQLVIKAADEALYRAKEGGRNCVSE

Sequences:

>Translated_384_residues
MDGIIQLSSENQGFSYILPYIVLSIVLLLSQPFNQGRIGMIAISMAIAYWIIQERLQVPLSYGTTRIEFTLTAFLLPICM
MATFIFPERRIFSKFGAGYLCILLFMFFWCWIITVHFADNDMTEIWQTYLLNIPEISPLPVIVVLYSIVMCGLSAIFVLT
RSNNTDLASYTCLLYSSLTFSLFSVDYISSTMFSIAGLLLLLYIISASHELAFIDQLTGIPGRRALESEMKHLGRTYTIA
MLDVDHFKKFNDTYGHDTGDDVLKLVASIMAQTGGNAKVYRYGGEEFTVLFKGKTAKQSLEYLEELREDIADYDLIIRDT
STRPKDNKEGQAKRGKANKTKVVNVTISIGVADSEDLRKPQLVIKAADEALYRAKEGGRNCVSE
>Mature_384_residues
MDGIIQLSSENQGFSYILPYIVLSIVLLLSQPFNQGRIGMIAISMAIAYWIIQERLQVPLSYGTTRIEFTLTAFLLPICM
MATFIFPERRIFSKFGAGYLCILLFMFFWCWIITVHFADNDMTEIWQTYLLNIPEISPLPVIVVLYSIVMCGLSAIFVLT
RSNNTDLASYTCLLYSSLTFSLFSVDYISSTMFSIAGLLLLLYIISASHELAFIDQLTGIPGRRALESEMKHLGRTYTIA
MLDVDHFKKFNDTYGHDTGDDVLKLVASIMAQTGGNAKVYRYGGEEFTVLFKGKTAKQSLEYLEELREDIADYDLIIRDT
STRPKDNKEGQAKRGKANKTKVVNVTISIGVADSEDLRKPQLVIKAADEALYRAKEGGRNCVSE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=296, Percent_Identity=29.0540540540541, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693134, Length=204, Percent_Identity=31.3725490196078, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787056, Length=175, Percent_Identity=31.4285714285714, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=173, Percent_Identity=34.1040462427746, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=29.1428571428571, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=31.2849162011173, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082007, Length=244, Percent_Identity=26.6393442622951, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=198, Percent_Identity=28.7878787878788, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 43236; Mature: 43236

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGIIQLSSENQGFSYILPYIVLSIVLLLSQPFNQGRIGMIAISMAIAYWIIQERLQVPL
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
SYGTTRIEFTLTAFLLPICMMATFIFPERRIFSKFGAGYLCILLFMFFWCWIITVHFADN
HCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHEEEECCC
DMTEIWQTYLLNIPEISPLPVIVVLYSIVMCGLSAIFVLTRSNNTDLASYTCLLYSSLTF
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHH
SLFSVDYISSTMFSIAGLLLLLYIISASHELAFIDQLTGIPGRRALESEMKHLGRTYTIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEEEE
MLDVDHFKKFNDTYGHDTGDDVLKLVASIMAQTGGNAKVYRYGGEEFTVLFKGKTAKQSL
EEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCHHHHH
EYLEELREDIADYDLIIRDTSTRPKDNKEGQAKRGKANKTKVVNVTISIGVADSEDLRKP
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHCCCC
QLVIKAADEALYRAKEGGRNCVSE
HHEEHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDGIIQLSSENQGFSYILPYIVLSIVLLLSQPFNQGRIGMIAISMAIAYWIIQERLQVPL
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
SYGTTRIEFTLTAFLLPICMMATFIFPERRIFSKFGAGYLCILLFMFFWCWIITVHFADN
HCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHEEEECCC
DMTEIWQTYLLNIPEISPLPVIVVLYSIVMCGLSAIFVLTRSNNTDLASYTCLLYSSLTF
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHH
SLFSVDYISSTMFSIAGLLLLLYIISASHELAFIDQLTGIPGRRALESEMKHLGRTYTIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEEEE
MLDVDHFKKFNDTYGHDTGDDVLKLVASIMAQTGGNAKVYRYGGEEFTVLFKGKTAKQSL
EEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCHHHHH
EYLEELREDIADYDLIIRDTSTRPKDNKEGQAKRGKANKTKVVNVTISIGVADSEDLRKP
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHCCCC
QLVIKAADEALYRAKEGGRNCVSE
HHEEHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]