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The map label for this gene is frdC [H]

Identifier: 59712943

GI number: 59712943

Start: 2626334

End: 2626717

Strand: Direct

Name: frdC [H]

Synonym: VF_2336

Alternate gene names: 59712943

Gene position: 2626334-2626717 (Clockwise)

Preceding gene: 59712942

Following gene: 59712944

Centisome position: 90.64

GC content: 42.45

Gene sequence:

>384_bases
ATGAGCAATCGTAAACCTTACGTTCGCGAAATGACACGTACTTGGTGGAAAGATCACCCTTTCTACCGCTTCTACATGGT
TCGTGAAGCAACGGTTCTACCACTAATTTTCTTTACTATCTGTCTGCTTGTTGGTCTAGGTAGTTTAGTTAAGGGTCCAC
TAGCTTGGGCTTCTTGGTTAGATTTCATGGCAAACCCTATTGTGGTTGCTCTGAACATTGTTGCTTTAGCTGGTAGCTTA
TTCCATGCTCAAACCTTCTTTAGCATGATGCCGCAAGTAATGCCGATTCGTCTTGGTGGTAAAACACTAGATAAGAAAGT
GGTTGTTCTTGCACAATGGGCAGCAGTTGCTGCTATCACATTACTTGTACTGGTTATCGTTTAA

Upstream 100 bases:

>100_bases
GTCCAAAACACGTTGACCCAGCAGCAGCTGTAAACCAAGGTAAGATCGCATCGTCTCAAGACTTTGTTATCGCAATGCTT
AAACCTCAGGAGGCATAAGG

Downstream 100 bases:

>100_bases
GGAGAATTATTGTGGTAAATCGTAATCCAAAGCGTTCTGACGAACCAGTATGGTGGGGCTTATTTGGTGCTGGCGGCACT
TGGTTTGCAATGCTAACACC

Product: fumarate reductase subunit C

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MSNRKPYVREMTRTWWKDHPFYRFYMVREATVLPLIFFTICLLVGLGSLVKGPLAWASWLDFMANPIVVALNIVALAGSL
FHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAITLLVLVIV

Sequences:

>Translated_127_residues
MSNRKPYVREMTRTWWKDHPFYRFYMVREATVLPLIFFTICLLVGLGSLVKGPLAWASWLDFMANPIVVALNIVALAGSL
FHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAITLLVLVIV
>Mature_126_residues
SNRKPYVREMTRTWWKDHPFYRFYMVREATVLPLIFFTICLLVGLGSLVKGPLAWASWLDFMANPIVVALNIVALAGSLF
HAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAITLLVLVIV

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3029

COG function: function code C; Fumarate reductase subunit C

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdC family [H]

Homologues:

Organism=Escherichia coli, GI1790595, Length=125, Percent_Identity=41.6, Blast_Score=120, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003510
- ProDom:   PD015900 [H]

Pfam domain/function: PF02300 Fumarate_red_C [H]

EC number: 1.3.99.1

Molecular weight: Translated: 14340; Mature: 14208

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRKPYVREMTRTWWKDHPFYRFYMVREATVLPLIFFTICLLVGLGSLVKGPLAWASWL
CCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFMANPIVVALNIVALAGSLFHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAIT
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHH
LLVLVIV
HHHHHHC
>Mature Secondary Structure 
SNRKPYVREMTRTWWKDHPFYRFYMVREATVLPLIFFTICLLVGLGSLVKGPLAWASWL
CCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFMANPIVVALNIVALAGSLFHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAIT
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHH
LLVLVIV
HHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA