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The map label for this gene is rsgA [H]

Identifier: 59712937

GI number: 59712937

Start: 2619374

End: 2620438

Strand: Direct

Name: rsgA [H]

Synonym: VF_2330

Alternate gene names: 59712937

Gene position: 2619374-2620438 (Clockwise)

Preceding gene: 59712935

Following gene: 59712938

Centisome position: 90.4

GC content: 38.59

Gene sequence:

>1065_bases
GTGGCAAAGAAGAAAAAGCTAACCAAAGGCCAAGTTCGCCGAGTACGCTCAAATCAAAAAAAGCGTATTGAAAAAATTGA
AGACAGTGTGCAATGGGATGAAACCCTACTAGAAGCTGCTAAAGAAGGCCTAGTCATTACACGCTTTGGTCAACATGCTG
ATATTGAAGACCCTGATACTAAAGACATCCATCGTTGTAATTTACGCCGAGGTATTGAAAGTTTAGTTTCGGGTGATCGT
GTTATTTGGCGTCCAGGGACTGAAGTCCTTGCTGGTATTTCAGGTGTTGTTGAAGCTGTAAAACCAAGAACATCAATGTT
AACCCGTCCAGACTATTATGATGGTATTAAGCCAGTAGCAGCTAACGTTGATCAAATGGTAATCGTATCTTCAATTCTTC
CTGAGTTGTCTCTTAATATTATTGATCGATACCTTATTGCTTCTGAAACTCTACATATCAAACCATTAATTGTATTAAAC
AAAGTGGATTTACTGTCTGAAGAAGAGTTCATCAAAGTACAGCAACTGCTTAGCTTATATGAAGATATTGGTTATAAAGT
TCGATATGTAAGTAAAGAATCAGGCTACGGTGTAGAAGAACTTGAAGCTGAATTACGAAATCACATTAATATTTTCGTTG
GTCAATCTGGCGTAGGTAAATCAAGCCTTGTAAATGCACTGATGCCTGAACTTGAGATTGAGGTGGAAGAAGGGGCAGTA
TCTGAAAACTCAGGTCTTGGTCAACATACAACAACTGCAGCACGCCTGTATCACTTCCCACACGGTGGTGATTTAATTGA
CTCTCCAGGAGTTCGTGAATTTGGTTTGTGGCACTTAGAAGCTGAACAAGTCACAGACTCTTTTATTGAATTTAAAGACT
TTTTAGGTGGCTGTAAGTTTAGAGACTGTAAACACAAAGATGACCCAGGATGCTTACTTCAAGAAGCCGTTGCAGAAGGT
AAAATCAATAAGCTACGATTTGAAAGCTATCATCGTATAATTGAAAGCATGTCTGAGAATAAAGCAAATCGCCAATTCTC
ACGAAACAAAAAAGCCGATTTATAA

Upstream 100 bases:

>100_bases
ATAGAGAGTTGCCTATTTTGTAACTAAAAAGGGTATGATACTCGGGCCGATTTATCTTTCAACATAAAACTGAAAGCCAA
CCAACAAGTGAATTAATTTC

Downstream 100 bases:

>100_bases
CCACAATAAACCTTGGGTTTAGCGACAATGTAAATATGTGGTAATATCCACAGCAAATGATAACTATTAGGCAAACAACG
TGTCAGATAATTTAAAGATT

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MAKKKKLTKGQVRRVRSNQKKRIEKIEDSVQWDETLLEAAKEGLVITRFGQHADIEDPDTKDIHRCNLRRGIESLVSGDR
VIWRPGTEVLAGISGVVEAVKPRTSMLTRPDYYDGIKPVAANVDQMVIVSSILPELSLNIIDRYLIASETLHIKPLIVLN
KVDLLSEEEFIKVQQLLSLYEDIGYKVRYVSKESGYGVEELEAELRNHINIFVGQSGVGKSSLVNALMPELEIEVEEGAV
SENSGLGQHTTTAARLYHFPHGGDLIDSPGVREFGLWHLEAEQVTDSFIEFKDFLGGCKFRDCKHKDDPGCLLQEAVAEG
KINKLRFESYHRIIESMSENKANRQFSRNKKADL

Sequences:

>Translated_354_residues
MAKKKKLTKGQVRRVRSNQKKRIEKIEDSVQWDETLLEAAKEGLVITRFGQHADIEDPDTKDIHRCNLRRGIESLVSGDR
VIWRPGTEVLAGISGVVEAVKPRTSMLTRPDYYDGIKPVAANVDQMVIVSSILPELSLNIIDRYLIASETLHIKPLIVLN
KVDLLSEEEFIKVQQLLSLYEDIGYKVRYVSKESGYGVEELEAELRNHINIFVGQSGVGKSSLVNALMPELEIEVEEGAV
SENSGLGQHTTTAARLYHFPHGGDLIDSPGVREFGLWHLEAEQVTDSFIEFKDFLGGCKFRDCKHKDDPGCLLQEAVAEG
KINKLRFESYHRIIESMSENKANRQFSRNKKADL
>Mature_353_residues
AKKKKLTKGQVRRVRSNQKKRIEKIEDSVQWDETLLEAAKEGLVITRFGQHADIEDPDTKDIHRCNLRRGIESLVSGDRV
IWRPGTEVLAGISGVVEAVKPRTSMLTRPDYYDGIKPVAANVDQMVIVSSILPELSLNIIDRYLIASETLHIKPLIVLNK
VDLLSEEEFIKVQQLLSLYEDIGYKVRYVSKESGYGVEELEAELRNHINIFVGQSGVGKSSLVNALMPELEIEVEEGAVS
ENSGLGQHTTTAARLYHFPHGGDLIDSPGVREFGLWHLEAEQVTDSFIEFKDFLGGCKFRDCKHKDDPGCLLQEAVAEGK
INKLRFESYHRIIESMSENKANRQFSRNKKADL

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover [H]

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain [H]

Homologues:

Organism=Escherichia coli, GI87082381, Length=346, Percent_Identity=60.4046242774566, Blast_Score=443, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010914
- InterPro:   IPR004881 [H]

Pfam domain/function: PF03193 DUF258 [H]

EC number: NA

Molecular weight: Translated: 39929; Mature: 39798

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKKKLTKGQVRRVRSNQKKRIEKIEDSVQWDETLLEAAKEGLVITRFGQHADIEDPDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
KDIHRCNLRRGIESLVSGDRVIWRPGTEVLAGISGVVEAVKPRTSMLTRPDYYDGIKPVA
HHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCHHHHCCCCCHHCCCCHHH
ANVDQMVIVSSILPELSLNIIDRYLIASETLHIKPLIVLNKVDLLSEEEFIKVQQLLSLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEECHHHHCHHHHHHHHHHHHHH
EDIGYKVRYVSKESGYGVEELEAELRNHINIFVGQSGVGKSSLVNALMPELEIEVEEGAV
HHCCCEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCHHEEEECCCCC
SENSGLGQHTTTAARLYHFPHGGDLIDSPGVREFGLWHLEAEQVTDSFIEFKDFLGGCKF
CCCCCCCCHHHHHHHHEECCCCCCCCCCCCCCHHCEEEEEHHHHHHHHHHHHHHHCCCCC
RDCKHKDDPGCLLQEAVAEGKINKLRFESYHRIIESMSENKANRQFSRNKKADL
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AKKKKLTKGQVRRVRSNQKKRIEKIEDSVQWDETLLEAAKEGLVITRFGQHADIEDPDT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
KDIHRCNLRRGIESLVSGDRVIWRPGTEVLAGISGVVEAVKPRTSMLTRPDYYDGIKPVA
HHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCHHHHCCCCCHHCCCCHHH
ANVDQMVIVSSILPELSLNIIDRYLIASETLHIKPLIVLNKVDLLSEEEFIKVQQLLSLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEECHHHHCHHHHHHHHHHHHHH
EDIGYKVRYVSKESGYGVEELEAELRNHINIFVGQSGVGKSSLVNALMPELEIEVEEGAV
HHCCCEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCHHEEEECCCCC
SENSGLGQHTTTAARLYHFPHGGDLIDSPGVREFGLWHLEAEQVTDSFIEFKDFLGGCKF
CCCCCCCCHHHHHHHHEECCCCCCCCCCCCCCHHCEEEEEHHHHHHHHHHHHHHHCCCCC
RDCKHKDDPGCLLQEAVAEGKINKLRFESYHRIIESMSENKANRQFSRNKKADL
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]