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The map label for this gene is xerD [H]

Identifier: 59712648

GI number: 59712648

Start: 2269891

End: 2270868

Strand: Direct

Name: xerD [H]

Synonym: VF_2041

Alternate gene names: 59712648

Gene position: 2269891-2270868 (Clockwise)

Preceding gene: 172087749

Following gene: 59712649

Centisome position: 78.34

GC content: 39.67

Gene sequence:

>978_bases
ATGTCTATAAGAAAACAACCAAACGGCAAGTATCTTGTTGAAATTTACCTACCGAATAAAAAACGCATCCGAAAAACCTT
TGCTACCCAAAGCGAAGCGAAACGCTTTGAACAATTTACGCAAACGGAATCCATTCAAAAACCGTGGATGCCAGCAAAAG
ACGATAACCGTACACTCAATGAATTAATAGAATTGTGGTATGGGTTACATGGCCAAGCATTAAGTGATGGCCCCAAACGA
AAAAACAAACTGCTCGCCATGTCTCTTATGATGAAAAACCCAATTGCAAGAGAGATTACCGCGAGCGATTTTTCAAAGTA
TCGCCAACTGCGTATTGAAACCGTTTCAATCAAAACAGCCAATAATGATCAAACTTATCTCAACGCATTATTTAATGAAT
TAAAACGCCTTGGCGAATGGAACTACAATAATCCACTCGCAGAACTGAGGGCATTAAAATACAAACAACCTGAAATGGGG
TTTTTAACAAGCGAAGAGATCACACTTGTTTTTGATGAATTAGAAAAGTGCCGCAACTTTGATGCGTACTTAATTTCTAA
AATATGCATATCAACGGGTTGTCGTTGGGGTGAAGCGGAATCATTAACCAGCACACAACTCACGCCGCACCGGATCACTT
TCACTCATACAAAAGGTAATAAGCACAGAACCGTTCCTATCAGTAAAGAACTCTACGAAGAACTACCAAAAAAGAACGGC
CGTTTATTTAGCAATTGTATTAAGTCTTTTAAAATGGCTGTAAATCGGACGGGAGTTCAACTCCCTAAAGGGCAATCAAC
TCACGTATTACGTCACACGTTTGCGAGTCATTTTATGATGAATGGAGGTAATATTTTGGTGTTACAACAGATTCTCGGCC
ATGCTAGTATCACTGACACAATGAAGTATGCACACTTTTCACCAGCGCACTTAGAAGATGCTATTAAGCTAAACCCACTC
GCCAAAAATGGCGGTTAA

Upstream 100 bases:

>100_bases
ATTTTCAATTACTCTTTATTGCTAAGAGTCTAATCAACGTCTTCACAAACAATGCTGCCCTAATAACCGGGCAGCATTTA
CACAACTCAAAGCCAAGCGT

Downstream 100 bases:

>100_bases
ATGGCGGCATTCGTGGCTGCTTATGGCTTTAGATGGTAGTTAACAACACTGTAAGCAATTGATAAGTAAAATAAGTGCTT
GTTTTTATTGTGTATGATGG

Product: DNA integration/recombination/invertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSIRKQPNGKYLVEIYLPNKKRIRKTFATQSEAKRFEQFTQTESIQKPWMPAKDDNRTLNELIELWYGLHGQALSDGPKR
KNKLLAMSLMMKNPIAREITASDFSKYRQLRIETVSIKTANNDQTYLNALFNELKRLGEWNYNNPLAELRALKYKQPEMG
FLTSEEITLVFDELEKCRNFDAYLISKICISTGCRWGEAESLTSTQLTPHRITFTHTKGNKHRTVPISKELYEELPKKNG
RLFSNCIKSFKMAVNRTGVQLPKGQSTHVLRHTFASHFMMNGGNILVLQQILGHASITDTMKYAHFSPAHLEDAIKLNPL
AKNGG

Sequences:

>Translated_325_residues
MSIRKQPNGKYLVEIYLPNKKRIRKTFATQSEAKRFEQFTQTESIQKPWMPAKDDNRTLNELIELWYGLHGQALSDGPKR
KNKLLAMSLMMKNPIAREITASDFSKYRQLRIETVSIKTANNDQTYLNALFNELKRLGEWNYNNPLAELRALKYKQPEMG
FLTSEEITLVFDELEKCRNFDAYLISKICISTGCRWGEAESLTSTQLTPHRITFTHTKGNKHRTVPISKELYEELPKKNG
RLFSNCIKSFKMAVNRTGVQLPKGQSTHVLRHTFASHFMMNGGNILVLQQILGHASITDTMKYAHFSPAHLEDAIKLNPL
AKNGG
>Mature_324_residues
SIRKQPNGKYLVEIYLPNKKRIRKTFATQSEAKRFEQFTQTESIQKPWMPAKDDNRTLNELIELWYGLHGQALSDGPKRK
NKLLAMSLMMKNPIAREITASDFSKYRQLRIETVSIKTANNDQTYLNALFNELKRLGEWNYNNPLAELRALKYKQPEMGF
LTSEEITLVFDELEKCRNFDAYLISKICISTGCRWGEAESLTSTQLTPHRITFTHTKGNKHRTVPISKELYEELPKKNGR
LFSNCIKSFKMAVNRTGVQLPKGQSTHVLRHTFASHFMMNGGNILVLQQILGHASITDTMKYAHFSPAHLEDAIKLNPLA
KNGG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37325; Mature: 37193

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRKQPNGKYLVEIYLPNKKRIRKTFATQSEAKRFEQFTQTESIQKPWMPAKDDNRTLN
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
ELIELWYGLHGQALSDGPKRKNKLLAMSLMMKNPIAREITASDFSKYRQLRIETVSIKTA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEEEEEC
NNDQTYLNALFNELKRLGEWNYNNPLAELRALKYKQPEMGFLTSEEITLVFDELEKCRNF
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
DAYLISKICISTGCRWGEAESLTSTQLTPHRITFTHTKGNKHRTVPISKELYEELPKKNG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCHHHHHHCCCCCC
RLFSNCIKSFKMAVNRTGVQLPKGQSTHVLRHTFASHFMMNGGNILVLQQILGHASITDT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCHHHHH
MKYAHFSPAHLEDAIKLNPLAKNGG
HHHCCCCHHHHHHHHEECCCCCCCC
>Mature Secondary Structure 
SIRKQPNGKYLVEIYLPNKKRIRKTFATQSEAKRFEQFTQTESIQKPWMPAKDDNRTLN
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
ELIELWYGLHGQALSDGPKRKNKLLAMSLMMKNPIAREITASDFSKYRQLRIETVSIKTA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEEEEEC
NNDQTYLNALFNELKRLGEWNYNNPLAELRALKYKQPEMGFLTSEEITLVFDELEKCRNF
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
DAYLISKICISTGCRWGEAESLTSTQLTPHRITFTHTKGNKHRTVPISKELYEELPKKNG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCHHHHHHCCCCCC
RLFSNCIKSFKMAVNRTGVQLPKGQSTHVLRHTFASHFMMNGGNILVLQQILGHASITDT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCHHHHH
MKYAHFSPAHLEDAIKLNPLAKNGG
HHHCCCCHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]