Click here to switch to the map view.

The map label for this gene is frr [H]

Identifier: 59712566

GI number: 59712566

Start: 2189538

End: 2190095

Strand: Reverse

Name: frr [H]

Synonym: VF_1959

Alternate gene names: 59712566

Gene position: 2190095-2189538 (Counterclockwise)

Preceding gene: 59712567

Following gene: 59712565

Centisome position: 75.58

GC content: 39.61

Gene sequence:

>558_bases
GTGATTAACGAAATTAAAAAAGATGCGCAAGAGCGTATGGAAAAAAGTGTTGAAGCACTGAAAAATAACCTGTTAAAAAT
TCGTACAGGTCGTGCTCACCCAAGTCTTCTTTCTGGTATCTCAGTAGAATACTACGGTGCTCAAACACCATTAAATCAAG
TTGCTAACGTTGTTGCGGAAGATTCACGTACGCTTGCAATTACGGTTTTCGATAAAGAACTTGCTGGTCTTGTTGAAAAA
GCAATCATGATGTCAGATCTTGGGCTAAACCCAATGTCAGCTGGTACGGTAATCCGTGTACCACTTCCACCACTAACTGA
AGAGCGTCGTAAAGACCTAGTTAAGATTGTTCGTGGTGAAGCTGAAAATGGCCGTGTTGCTATTCGTAATATCCGTCGTG
ATGCAAATGGTGATGTGAAAGCGCTTCTTAAAGAGAAAGAAATTTCTGAAGATGATGATCGTCGTGCACAAGATGAGATT
CAAAAGCTTACAGATGCTGCTGTTAAGAGTATTGATGAAGTACTTGCAGTAAAAGAAAAAGAGTTAATGGAAGTATAA

Upstream 100 bases:

>100_bases
CTGGTGCATTACGTCGTGTAGTTATGGGTGAAACTGAAGGCACACTGATCAGCAACGCTGAATAATTCTCCTACGAATCA
AAAATAATCAAGGTGATCTT

Downstream 100 bases:

>100_bases
TTGCTTTCATGCTCATTGTTCTCACTGATCTTTTCATTAAATTAATGATATGATGTCGGCGACGAACACCATAAGAAGCG
CTGGGTGGAGACATCAGCGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGISVEYYGAQTPLNQVANVVAEDSRTLAITVFDKELAGLVEK
AIMMSDLGLNPMSAGTVIRVPLPPLTEERRKDLVKIVRGEAENGRVAIRNIRRDANGDVKALLKEKEISEDDDRRAQDEI
QKLTDAAVKSIDEVLAVKEKELMEV

Sequences:

>Translated_185_residues
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGISVEYYGAQTPLNQVANVVAEDSRTLAITVFDKELAGLVEK
AIMMSDLGLNPMSAGTVIRVPLPPLTEERRKDLVKIVRGEAENGRVAIRNIRRDANGDVKALLKEKEISEDDDRRAQDEI
QKLTDAAVKSIDEVLAVKEKELMEV
>Mature_185_residues
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGISVEYYGAQTPLNQVANVVAEDSRTLAITVFDKELAGLVEK
AIMMSDLGLNPMSAGTVIRVPLPPLTEERRKDLVKIVRGEAENGRVAIRNIRRDANGDVKALLKEKEISEDDDRRAQDEI
QKLTDAAVKSIDEVLAVKEKELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=32.4022346368715, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=32, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=70.8108108108108, Blast_Score=264, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20573; Mature: 20573

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGISVEYYGAQTPLNQVANVVAE
CCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHCCCEEECCCCCCHHHHHHHHHC
DSRTLAITVFDKELAGLVEKAIMMSDLGLNPMSAGTVIRVPLPPLTEERRKDLVKIVRGE
CCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
AENGRVAIRNIRRDANGDVKALLKEKEISEDDDRRAQDEIQKLTDAAVKSIDEVLAVKEK
CCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGISVEYYGAQTPLNQVANVVAE
CCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHCCCEEECCCCCCHHHHHHHHHC
DSRTLAITVFDKELAGLVEKAIMMSDLGLNPMSAGTVIRVPLPPLTEERRKDLVKIVRGE
CCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
AENGRVAIRNIRRDANGDVKALLKEKEISEDDDRRAQDEIQKLTDAAVKSIDEVLAVKEK
CCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA