Click here to switch to the map view.

The map label for this gene is cdsA [H]

Identifier: 59712564

GI number: 59712564

Start: 2187800

End: 2188579

Strand: Reverse

Name: cdsA [H]

Synonym: VF_1957

Alternate gene names: 59712564

Gene position: 2188579-2187800 (Counterclockwise)

Preceding gene: 59712565

Following gene: 59712563

Centisome position: 75.53

GC content: 38.72

Gene sequence:

>780_bases
ATGTTGCCAATGCAAGGGTTCTTAATTGCTATCACAGCAATTACATTGGTTGGATTCTGGGAGTGGACTCAGTTTACAGA
ATCAAAATCTCGCTATTTAGCTATTATCCCTTCTGTTGCTGTCTTAGCAGCGTCCCTGTTTTTTCTTCCAACATCAACGT
TAGAACTGACAATACCTAGTAATGAACATCAAATAATATTATTAGTTGGTTTTACATGGTGGTTAATTGCATCGGGGTTA
GTGCTTACTTTCCCAAACAGCAAAAAATTATGGCATAGCAACTTACCTTTAAAGCATATTTTCGGTTGGCTAACCATGGT
TCCTTTCCTATGGAGTATTTTATTACTTCGTGCTGATCACTATATGCTAGACAGTTATTATGGCGCTAAGCTTGTATTAC
TCGTTTGTTTATTAGTATGGGCTGCGGATAGTGGCGCTTATTTTGCTGGAAAGTCATTTGGTAAACGTAAAATGTCACCA
GCGGTGAGCCCGAATAAAACGATCGAAGGCCTTATTGGGGGCGTGATTACCGCAATCATCATTGGTTGGGGGGCTGCAAG
TGCCTTTAATATTCAATTTGAAAGCACATCGTCAATGTTAGGTATTTTTATCGCAACAATTATCATCTCTGTTCTCGGTG
ATTTAGTTGAAAGTATGTTTAAACGTGCTTCAGGAATTAAAGATAGCGGTACGATTATCCCAGGTCACGGCGGTATTTTA
GATCGCATTGATAGTTTAACTGCGGCTTTTCCTGTTTTTGCTTTTTTATATTTCTTCTAG

Upstream 100 bases:

>100_bases
ACAAATCCAAGCTCTAATGAACGAAAAGGATCAATAAAGTTTGAAACAGCGTATTATTACTGCTCTTATTTTGGCGCCCC
TTGTTATTGCAGGGATCTTC

Downstream 100 bases:

>100_bases
CTGATATTAGGTATTTGACGACAAATACCATATCCATTTTTAAGTTATGCGGTAGATAGGATTATCTGCCGTTTTTCTAT
CTTTAAACCACCATGGTCAT

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLPMQGFLIAITAITLVGFWEWTQFTESKSRYLAIIPSVAVLAASLFFLPTSTLELTIPSNEHQIILLVGFTWWLIASGL
VLTFPNSKKLWHSNLPLKHIFGWLTMVPFLWSILLLRADHYMLDSYYGAKLVLLVCLLVWAADSGAYFAGKSFGKRKMSP
AVSPNKTIEGLIGGVITAIIIGWGAASAFNIQFESTSSMLGIFIATIIISVLGDLVESMFKRASGIKDSGTIIPGHGGIL
DRIDSLTAAFPVFAFLYFF

Sequences:

>Translated_259_residues
MLPMQGFLIAITAITLVGFWEWTQFTESKSRYLAIIPSVAVLAASLFFLPTSTLELTIPSNEHQIILLVGFTWWLIASGL
VLTFPNSKKLWHSNLPLKHIFGWLTMVPFLWSILLLRADHYMLDSYYGAKLVLLVCLLVWAADSGAYFAGKSFGKRKMSP
AVSPNKTIEGLIGGVITAIIIGWGAASAFNIQFESTSSMLGIFIATIIISVLGDLVESMFKRASGIKDSGTIIPGHGGIL
DRIDSLTAAFPVFAFLYFF
>Mature_259_residues
MLPMQGFLIAITAITLVGFWEWTQFTESKSRYLAIIPSVAVLAASLFFLPTSTLELTIPSNEHQIILLVGFTWWLIASGL
VLTFPNSKKLWHSNLPLKHIFGWLTMVPFLWSILLLRADHYMLDSYYGAKLVLLVCLLVWAADSGAYFAGKSFGKRKMSP
AVSPNKTIEGLIGGVITAIIIGWGAASAFNIQFESTSSMLGIFIATIIISVLGDLVESMFKRASGIKDSGTIIPGHGGIL
DRIDSLTAAFPVFAFLYFF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=259, Percent_Identity=47.8764478764479, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787677, Length=118, Percent_Identity=45.7627118644068, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28433; Mature: 28433

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPMQGFLIAITAITLVGFWEWTQFTESKSRYLAIIPSVAVLAASLFFLPTSTLELTIPS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECC
NEHQIILLVGFTWWLIASGLVLTFPNSKKLWHSNLPLKHIFGWLTMVPFLWSILLLRADH
CCCEEEEEEHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YMLDSYYGAKLVLLVCLLVWAADSGAYFAGKSFGKRKMSPAVSPNKTIEGLIGGVITAII
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
IGWGAASAFNIQFESTSSMLGIFIATIIISVLGDLVESMFKRASGIKDSGTIIPGHGGIL
HHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHH
DRIDSLTAAFPVFAFLYFF
HHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLPMQGFLIAITAITLVGFWEWTQFTESKSRYLAIIPSVAVLAASLFFLPTSTLELTIPS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECC
NEHQIILLVGFTWWLIASGLVLTFPNSKKLWHSNLPLKHIFGWLTMVPFLWSILLLRADH
CCCEEEEEEHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YMLDSYYGAKLVLLVCLLVWAADSGAYFAGKSFGKRKMSPAVSPNKTIEGLIGGVITAII
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
IGWGAASAFNIQFESTSSMLGIFIATIIISVLGDLVESMFKRASGIKDSGTIIPGHGGIL
HHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHH
DRIDSLTAAFPVFAFLYFF
HHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]