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The map label for this gene is narP [H]

Identifier: 59712516

GI number: 59712516

Start: 2141876

End: 2142487

Strand: Direct

Name: narP [H]

Synonym: VF_1909

Alternate gene names: 59712516

Gene position: 2141876-2142487 (Clockwise)

Preceding gene: 59712515

Following gene: 59712517

Centisome position: 73.92

GC content: 38.56

Gene sequence:

>612_bases
ATGTGGAATGTCGTTATCGTTGATGATCATCCGTTAATGCGTCGTGGTATTGGTCAACTTCTTTCTTTTGATGAAGAATT
CACACTGACTGGCGAAGCAAGTAATGGTACTGATGCCGTTGCTCTGATTTCACAAGATGAACCAGACCTTGTTCTTCTTG
ATCTAAATATGAAAGGCATGTCAGGTTTAGATACGTTGCATGCGCTAAGAAATGAAGGGGTAACTTGCCCTATTGTCATT
TTAACCGTGTCAGATAATAAGCAAGACATCAAAACATTAATTAAAGCTGGGGCAGATGGTTATCTACTAAAAGATAGTGA
ACCTGATGAACTAATCGCATTATTAAAAGAAGCGATGAAAGGCGGCAAAGCCTACTCTGAACAAGTTAAAACGTGTTTAG
AAGAAGACGCTCAAGGCGACGACAAATTATCTCAACTAACCGCTCGTGAATTAGAAATTTTGCAACATGTAGCAAAAGGA
ATGAGAAACAAGCAAGTTGCGGATAAACTTTTTATCTCTGAAGCGACTGTAAAAGTCCACATGAAGAGTTTGCTGAAAAA
ATTAAATGTAAAATCCCGTGTTGCAGCAACGCTACTGTATTTAGATTCGTGA

Upstream 100 bases:

>100_bases
GCGTTCATGGTAAGCTATCCATAACTTCAGAAATAGACAACGGTTGTACAGTGAACGTTATGTTTCCACTAAACCAATAA
AATAATAGAGGTAAAAAATT

Downstream 100 bases:

>100_bases
TATGAAAAAAACGTTTTATTCACTCTTATTTCTATTGGTACTAAATGGTTGTGCATTAACAACAGAGCCAATGACTCCTG
AATCAAGTGCTATCAACTTA

Product: DNA-binding response regulator in two-component regulatory system with NarQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MWNVVIVDDHPLMRRGIGQLLSFDEEFTLTGEASNGTDAVALISQDEPDLVLLDLNMKGMSGLDTLHALRNEGVTCPIVI
LTVSDNKQDIKTLIKAGADGYLLKDSEPDELIALLKEAMKGGKAYSEQVKTCLEEDAQGDDKLSQLTARELEILQHVAKG
MRNKQVADKLFISEATVKVHMKSLLKKLNVKSRVAATLLYLDS

Sequences:

>Translated_203_residues
MWNVVIVDDHPLMRRGIGQLLSFDEEFTLTGEASNGTDAVALISQDEPDLVLLDLNMKGMSGLDTLHALRNEGVTCPIVI
LTVSDNKQDIKTLIKAGADGYLLKDSEPDELIALLKEAMKGGKAYSEQVKTCLEEDAQGDDKLSQLTARELEILQHVAKG
MRNKQVADKLFISEATVKVHMKSLLKKLNVKSRVAATLLYLDS
>Mature_203_residues
MWNVVIVDDHPLMRRGIGQLLSFDEEFTLTGEASNGTDAVALISQDEPDLVLLDLNMKGMSGLDTLHALRNEGVTCPIVI
LTVSDNKQDIKTLIKAGADGYLLKDSEPDELIALLKEAMKGGKAYSEQVKTCLEEDAQGDDKLSQLTARELEILQHVAKG
MRNKQVADKLFISEATVKVHMKSLLKKLNVKSRVAATLLYLDS

Specific function: Could activate the expression of a formate dehydrogenase operon and could repress the transcription of the fumarate reductase (frdABCD) operon [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=203, Percent_Identity=54.679802955665, Blast_Score=216, Evalue=9e-58,
Organism=Escherichia coli, GI1787473, Length=200, Percent_Identity=44.5, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1788222, Length=205, Percent_Identity=29.7560975609756, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1790102, Length=194, Percent_Identity=31.4432989690722, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788712, Length=194, Percent_Identity=30.4123711340206, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786747, Length=194, Percent_Identity=23.1958762886598, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=28.4313725490196, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22307; Mature: 22307

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWNVVIVDDHPLMRRGIGQLLSFDEEFTLTGEASNGTDAVALISQDEPDLVLLDLNMKGM
CCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCC
SGLDTLHALRNEGVTCPIVILTVSDNKQDIKTLIKAGADGYLLKDSEPDELIALLKEAMK
CHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH
GGKAYSEQVKTCLEEDAQGDDKLSQLTARELEILQHVAKGMRNKQVADKLFISEATVKVH
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
MKSLLKKLNVKSRVAATLLYLDS
HHHHHHHHCHHHHHHHHEEEECC
>Mature Secondary Structure
MWNVVIVDDHPLMRRGIGQLLSFDEEFTLTGEASNGTDAVALISQDEPDLVLLDLNMKGM
CCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCC
SGLDTLHALRNEGVTCPIVILTVSDNKQDIKTLIKAGADGYLLKDSEPDELIALLKEAMK
CHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH
GGKAYSEQVKTCLEEDAQGDDKLSQLTARELEILQHVAKGMRNKQVADKLFISEATVKVH
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
MKSLLKKLNVKSRVAATLLYLDS
HHHHHHHHCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]