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The map label for this gene is norR1

Identifier: 59712390

GI number: 59712390

Start: 2012284

End: 2013822

Strand: Direct

Name: norR1

Synonym: VF_1783

Alternate gene names: 59712390

Gene position: 2012284-2013822 (Clockwise)

Preceding gene: 59712385

Following gene: 59712391

Centisome position: 69.45

GC content: 38.4

Gene sequence:

>1539_bases
ATGAAAAATATTAAAGATGAATGGGTTCAAATTGCATTGGATCTCACCTCTGGATTATCAAGCAAAGATCGTTTTGAACG
TTTGTTATCAACGATCAGAAATGCCTTAAAATGCGATGCTTCCGCTCTTCTATTATTTAAAAATCAGTATTTTTCTCCTC
TTGCTACCAATGGCTTAGACGGCGATGTCATTGGTCGTCGTTTTGCTATTTCTCAACATCCTCGTTTAGAGGCGATTGCC
CGAGCTGGAGACATTGTTCGATTTCCTTCAGATAGTGATTTACCAGATCCTTATGATGGTCTGATTGCTAACGAAGAGCG
TCAGTTGCAGGTCCACTCATGTATTGGGTTACCTCTGCTGGTTAATGAACGATTAATTGGAGCAGTCACAATAGATGCAT
TTGACCCTACTCAATTTGATTCATTTACAAACAAAGAGTTAAGAATAATCAGTGCATTAGCAGCAACTAGCTTGCATACC
GCTTTATTGATGGAAAGATTAGAAAATCAATCGGGAGAAAACTCAAATAACTCATCATTTGAGCGATCACCTGATAATCA
CGTTGAAATGATTGGTGAATCCCTTGCAATGCAAGAGTTGCAAGCCAATATTAACGCAGTTGCTAATACAGAATTATCCG
TATTAATTACGGGCGAAACCGGTGTGGGTAAAGAACTGGTTGCGAGTGCTTTACATCAAAGATCAACACGAGCACAACAA
AACTTAGTGTATTTAAACTGCGCGGCATTACCTGAATCCGTTGCAGAAAGTGAACTATTTGGACACGTTAAAGGCGCTTT
TACTGGGGCGATCAGTAACAGAAAAGGGAAATTTGAATCTGCTGACAATGGTACGCTATTTCTAGATGAGATAGGCGAGC
TATCATTGGCTCTACAGGCTAAATTACTGCGTGTTTTACAATATGGTGATATTCAACGTATTGGTGATGACAACCATATT
AAGGTAAATACACGAATTATCGCAGCAACCAACAAAACACTGAGTGATGAGGTAAAAAATGGTGATTTTCGTGCTGACTT
ATATCATCGATTGAGTGTCTTCCCTATTTTTGTTCCACCGCTTAGAGACAGAGGTAATGACGTCACTTTACTCGTTGGTT
ACTTTGCAGAAAAGAGTCGTATTAAACTAGCGGCGACGAGTATACGAATCACACCTGAAGCCATCACTTTACTTAATGAC
TATTCATGGCCTGGGAATATTCGAGAATTAGAGCATGTAATAAGCCGAGCTGCCGTTTTATCAAGAGCTCAAAGTGACGA
TTCTGATTTAGTATTATCTCCCACACATTTCTTAATAAAAAAAGAAAATCATGCAGAAAAAAACATAGCGAATCAAATTG
TTACACCACATTCAAAAAACACCAAAGATCTACGCTCTGCTACGGATGAATTTCAAGCTAATTTAATTAAAAAAACATAT
CAAGAACAGCAACAAAATTGGGCTGCAACCGCCAGAGCATTGCAACTTGATACAGGAAATTTACATCGTTTAGCAAAACG
GTTAAATCTAAAAGAGTAA

Upstream 100 bases:

>100_bases
AATAAATTCACCCACAAAAGTGTCATTATGACAATCATTTACTTTTGTCAAAACGACACTATAATTGTCAAATTAACACT
GTTTATATCACGAGGTTTCA

Downstream 100 bases:

>100_bases
AAGCAATAAATAAACATATTTTTACCGATATAATTATGTGATTTTGCTCTCGGATCTGTCCCACGCATATTCTTTCTGTT
AGAATCTGCCTCAAGTTTTA

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MKNIKDEWVQIALDLTSGLSSKDRFERLLSTIRNALKCDASALLLFKNQYFSPLATNGLDGDVIGRRFAISQHPRLEAIA
RAGDIVRFPSDSDLPDPYDGLIANEERQLQVHSCIGLPLLVNERLIGAVTIDAFDPTQFDSFTNKELRIISALAATSLHT
ALLMERLENQSGENSNNSSFERSPDNHVEMIGESLAMQELQANINAVANTELSVLITGETGVGKELVASALHQRSTRAQQ
NLVYLNCAALPESVAESELFGHVKGAFTGAISNRKGKFESADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRIGDDNHI
KVNTRIIAATNKTLSDEVKNGDFRADLYHRLSVFPIFVPPLRDRGNDVTLLVGYFAEKSRIKLAATSIRITPEAITLLND
YSWPGNIRELEHVISRAAVLSRAQSDDSDLVLSPTHFLIKKENHAEKNIANQIVTPHSKNTKDLRSATDEFQANLIKKTY
QEQQQNWAATARALQLDTGNLHRLAKRLNLKE

Sequences:

>Translated_512_residues
MKNIKDEWVQIALDLTSGLSSKDRFERLLSTIRNALKCDASALLLFKNQYFSPLATNGLDGDVIGRRFAISQHPRLEAIA
RAGDIVRFPSDSDLPDPYDGLIANEERQLQVHSCIGLPLLVNERLIGAVTIDAFDPTQFDSFTNKELRIISALAATSLHT
ALLMERLENQSGENSNNSSFERSPDNHVEMIGESLAMQELQANINAVANTELSVLITGETGVGKELVASALHQRSTRAQQ
NLVYLNCAALPESVAESELFGHVKGAFTGAISNRKGKFESADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRIGDDNHI
KVNTRIIAATNKTLSDEVKNGDFRADLYHRLSVFPIFVPPLRDRGNDVTLLVGYFAEKSRIKLAATSIRITPEAITLLND
YSWPGNIRELEHVISRAAVLSRAQSDDSDLVLSPTHFLIKKENHAEKNIANQIVTPHSKNTKDLRSATDEFQANLIKKTY
QEQQQNWAATARALQLDTGNLHRLAKRLNLKE
>Mature_512_residues
MKNIKDEWVQIALDLTSGLSSKDRFERLLSTIRNALKCDASALLLFKNQYFSPLATNGLDGDVIGRRFAISQHPRLEAIA
RAGDIVRFPSDSDLPDPYDGLIANEERQLQVHSCIGLPLLVNERLIGAVTIDAFDPTQFDSFTNKELRIISALAATSLHT
ALLMERLENQSGENSNNSSFERSPDNHVEMIGESLAMQELQANINAVANTELSVLITGETGVGKELVASALHQRSTRAQQ
NLVYLNCAALPESVAESELFGHVKGAFTGAISNRKGKFESADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRIGDDNHI
KVNTRIIAATNKTLSDEVKNGDFRADLYHRLSVFPIFVPPLRDRGNDVTLLVGYFAEKSRIKLAATSIRITPEAITLLND
YSWPGNIRELEHVISRAAVLSRAQSDDSDLVLSPTHFLIKKENHAEKNIANQIVTPHSKNTKDLRSATDEFQANLIKKTY
QEQQQNWAATARALQLDTGNLHRLAKRLNLKE

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain

Homologues:

Organism=Escherichia coli, GI87082152, Length=507, Percent_Identity=56.8047337278106, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI87082117, Length=237, Percent_Identity=52.3206751054852, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1788550, Length=228, Percent_Identity=53.5087719298246, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789087, Length=324, Percent_Identity=41.358024691358, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1790437, Length=235, Percent_Identity=53.1914893617021, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789233, Length=391, Percent_Identity=35.8056265984655, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1790299, Length=236, Percent_Identity=46.6101694915254, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=39.4409937888199, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1788905, Length=321, Percent_Identity=35.8255451713396, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1786524, Length=283, Percent_Identity=38.5159010600707, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787583, Length=229, Percent_Identity=41.0480349344978, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789828, Length=227, Percent_Identity=36.1233480176211, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081858, Length=236, Percent_Identity=33.0508474576271, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NORR_VIBF1 (Q5E3W8)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205166.1
- HSSP:   P25852
- ProteinModelPortal:   Q5E3W8
- SMR:   Q5E3W8
- STRING:   Q5E3W8
- GeneID:   3279017
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_1783
- NMPDR:   fig|312309.3.peg.1783
- eggNOG:   COG3604
- HOGENOM:   HBG740884
- OMA:   RATRNGD
- PhylomeDB:   Q5E3W8
- ProtClustDB:   PRK05022
- BioCyc:   VFIS312309:VF1783-MONOMER
- GO:   GO:0005622
- GO:   GO:0006350
- HAMAP:   MF_01314
- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078
- SMART:   SM00382
- SMART:   SM00065

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 56768; Mature: 56768

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00675 SIGMA54_INTERACT_1; PS00676 SIGMA54_INTERACT_2; PS00688 SIGMA54_INTERACT_3; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIKDEWVQIALDLTSGLSSKDRFERLLSTIRNALKCDASALLLFKNQYFSPLATNGLD
CCCCHHHHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCC
GDVIGRRFAISQHPRLEAIARAGDIVRFPSDSDLPDPYDGLIANEERQLQVHSCIGLPLL
CCCCCCEEECCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHEEEEHHCCCCEE
VNERLIGAVTIDAFDPTQFDSFTNKELRIISALAATSLHTALLMERLENQSGENSNNSSF
ECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ERSPDNHVEMIGESLAMQELQANINAVANTELSVLITGETGVGKELVASALHQRSTRAQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
NLVYLNCAALPESVAESELFGHVKGAFTGAISNRKGKFESADNGTLFLDEIGELSLALQA
CEEEEEECCCCHHHHHHHHHHHHHHHHHEHHCCCCCCCCCCCCCEEEEECHHHHHHHHHH
KLLRVLQYGDIQRIGDDNHIKVNTRIIAATNKTLSDEVKNGDFRADLYHRLSVFPIFVPP
HHHHHHHCCCHHCCCCCCEEEEEEEEEEECCCCHHHHHCCCCCHHHHHHHHEEEEEEECC
LRDRGNDVTLLVGYFAEKSRIKLAATSIRITPEAITLLNDYSWPGNIRELEHVISRAAVL
CCCCCCEEEEEEEECCCCCCEEEEEEEEEECHHHHEEEECCCCCCCHHHHHHHHHHHHHH
SRAQSDDSDLVLSPTHFLIKKENHAEKNIANQIVTPHSKNTKDLRSATDEFQANLIKKTY
HHCCCCCCCEEECCCEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QEQQQNWAATARALQLDTGNLHRLAKRLNLKE
HHHHHHHHHHHHEEEECCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKNIKDEWVQIALDLTSGLSSKDRFERLLSTIRNALKCDASALLLFKNQYFSPLATNGLD
CCCCHHHHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCC
GDVIGRRFAISQHPRLEAIARAGDIVRFPSDSDLPDPYDGLIANEERQLQVHSCIGLPLL
CCCCCCEEECCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHEEEEHHCCCCEE
VNERLIGAVTIDAFDPTQFDSFTNKELRIISALAATSLHTALLMERLENQSGENSNNSSF
ECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ERSPDNHVEMIGESLAMQELQANINAVANTELSVLITGETGVGKELVASALHQRSTRAQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
NLVYLNCAALPESVAESELFGHVKGAFTGAISNRKGKFESADNGTLFLDEIGELSLALQA
CEEEEEECCCCHHHHHHHHHHHHHHHHHEHHCCCCCCCCCCCCCEEEEECHHHHHHHHHH
KLLRVLQYGDIQRIGDDNHIKVNTRIIAATNKTLSDEVKNGDFRADLYHRLSVFPIFVPP
HHHHHHHCCCHHCCCCCCEEEEEEEEEEECCCCHHHHHCCCCCHHHHHHHHEEEEEEECC
LRDRGNDVTLLVGYFAEKSRIKLAATSIRITPEAITLLNDYSWPGNIRELEHVISRAAVL
CCCCCCEEEEEEEECCCCCCEEEEEEEEEECHHHHEEEECCCCCCCHHHHHHHHHHHHHH
SRAQSDDSDLVLSPTHFLIKKENHAEKNIANQIVTPHSKNTKDLRSATDEFQANLIKKTY
HHCCCCCCCEEECCCEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QEQQQNWAATARALQLDTGNLHRLAKRLNLKE
HHHHHHHHHHHHEEEECCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA